WO2019098637A2 - Composition cosmétique de type eau dans silicone comprenant un agent d'écran solaire organique - Google Patents

Composition cosmétique de type eau dans silicone comprenant un agent d'écran solaire organique Download PDF

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WO2019098637A2
WO2019098637A2 PCT/KR2018/013778 KR2018013778W WO2019098637A2 WO 2019098637 A2 WO2019098637 A2 WO 2019098637A2 KR 2018013778 W KR2018013778 W KR 2018013778W WO 2019098637 A2 WO2019098637 A2 WO 2019098637A2
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composition
cosmetic composition
silicone
water
present
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Korean (ko)
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WO2019098637A3 (fr
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임형준
박정은
김선영
서병휘
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Amorepacific Corp
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Amorepacific Corp
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Priority claimed from KR1020180096027A external-priority patent/KR102587916B1/ko
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Priority to SG11202004334TA priority Critical patent/SG11202004334TA/en
Priority to CN201880073976.8A priority patent/CN111432789A/zh
Publication of WO2019098637A2 publication Critical patent/WO2019098637A2/fr
Publication of WO2019098637A3 publication Critical patent/WO2019098637A3/fr
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241—Containing particulates characterized by their shape and/or structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A61K8/064—Water-in-oil emulsions, e.g. Water-in-silicone emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4966—Triazines or their condensed derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/738—Cyclodextrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89—Polysiloxanes
    • A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • A61K8/894—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone modified by a polyoxyalkylene group, e.g. cetyl dimethicone copolyol

Definitions

  • the present invention relates to a cosmetic composition of the silicone water-repellent type comprising an organic UV-blocking agent.
  • UV-C ultraviolet-C
  • UV-B UV-B
  • UV-A UV-A
  • UV-C penetrates into the epidermis of the skin and causes erythema, freckles and edema
  • UV-A penetrates into the skin's dermis and forms wrinkles and melanin To promote skin aging and skin irritation, and to cause skin cancer.
  • the market for the UV ray-blocking product is growing year by year, and the consumer's needs for the cosmetic composition for protecting the UV ray over the entire wavelength range is increasing to be.
  • a cosmetic composition for ultraviolet ray shielding has been proposed as a water-in-oil type in which oil is traumatized or an oil-in-water type in which water is traumatized.
  • the W / O type has a longer persistence than the O / W type but has a disadvantage that the feeling of use is heavy and sticky, which is not related to the high viscosity of a general W / O type product.
  • the W / O type product has a disadvantage in that the emulsion stability is lower than that of the O / W type, since the product of the W / O type is made to have a high viscosity by raising the ratio of the internal phase water phase to lightly control the feeling.
  • W / O type products having a low viscosity have a problem that the stability of the product deteriorates due to the separation of the water phase from the internal phase and the external phase (oil phase) during long-term storage in a container during circulation. Therefore, the viscosity is increased to increase the stability and the viscosity is increased, so that the feeling of use becomes heavy and sticky.
  • organic UV blocking agents have poor stability to heat and light.
  • bis-ethylhexyloxyphenol methoxyphenyltriazine has poor solubility in solvents and dissolves in oil having high polarity such as alkyl benzoate. I had to apply it to my daily life.
  • composite particles containing an organic UV-blocking agent such as bis-ethylhexyloxyphenol methoxyphenyltriazine and the like have been proposed, but the problem of solubility has not been completely solved.
  • the present inventors have focused on the problems of the conventional cosmetic composition for ultraviolet ray shielding, proposed a cosmetic composition of silicone water-repellent type which has water resistance and can impart both light adhesion and silky feel as well as good adhesion strength Respectively.
  • a cosmetic composition of the silicone water-type type which can stably contain bis-ethylhexyloxyphenol methoxyphenyltriazine, which was not applicable to the silicone-based trauma due to the solubility problem, Completed.
  • an object of the present invention is to ensure a stable formulation comprising bis-ethylhexyloxyphenol methoxyphenyltriazine, which was not applicable to silicone-based trauma due to solubility problems. That is, an object of the present invention is to provide a stable silicone heavy type cosmetic composition comprising bis-ethylhexyloxyphenol methoxyphenyltriazine.
  • one aspect of the present invention provides a cosmetic composition of the silicone water-repellent type comprising microparticles comprising bis-ethylhexyloxyphenol methoxyphenyltriazine.
  • the cosmetic composition of the silicone water-repellent type is a cosmetic composition for blocking ultraviolet rays.
  • the microparticles contain bis-ethylhexyloxyphenol methoxyphenyltriazine in an amount of 20% by weight or more based on the total weight of the microparticles Lt; / RTI >
  • the microparticles may be hemispherical.
  • the microparticles may have an average diameter ranging from 1 to 10 mu m.
  • the cosmetic composition of the silicone water type according to an embodiment of the present invention may further include a phenylbenzimidazole-based compound and a cyclodextrin-based compound in the aqueous phase.
  • the phenylbenzimidazole-based compound and the cyclodextrin-based compound may be contained in a weight ratio of 1: 0.1 to 1:10.
  • the pH of the cosmetic composition of the silicone heavy water type according to an embodiment of the present invention may be at least 7.5, and in particular, the silicone heavy water type cosmetic composition comprising the phenylbenzimidazole compound and the cyclodextrin compound has a pH , It is possible to realize the boosting effect in the SPF as well as the improved formulation stability.
  • the cosmetic composition of the silicone water type according to an embodiment of the present invention may satisfy the following relational expression (1).
  • A is the amount (g) of bis-ethylhexyloxyphenol methoxyphenyltriazine used,
  • the cosmetic composition of the silicone water type comprises a polar oil containing at least one polar functional group selected from a carboxyl group (COO), a ketone group (CO) and a hydroxyl group (OH) , And 0 to 1% by weight, based on the total weight of the composition.
  • a polar oil containing at least one polar functional group selected from a carboxyl group (COO), a ketone group (CO) and a hydroxyl group (OH) , And 0 to 1% by weight, based on the total weight of the composition.
  • the composition may further comprise a PEG-containing silicone surfactant.
  • the cosmetic composition of the silicone water type according to an embodiment of the present invention may contain 0.1 to 10% by weight of the bis-ethylhexyloxyphenol methoxyphenyltriazine based on the total weight of the composition.
  • the cosmetic composition of the silicone water type according to an embodiment of the present invention contains 15 wt% or less of an organic UV-blocking agent including bis-ethylhexyloxyphenol methoxyphenyltriazine,
  • the ultraviolet barrier index of the composition may be at least 30.
  • UV cutoff index (minimum erythema amount of the skin part applied with the cosmetic composition of the silicone water type) / (minimum erythema amount of the skin part not coated with the silicone water type cosmetic composition)
  • an insoluble silicone water type formulation using bis-ethylhexyloxyphenol methoxyphenyltriazine which was not applicable to silicone formulation due to solubility problems, can be secured.
  • silicone water-type cosmetic composition which imparts a feeling of lightness and refreshing feeling at the same time, imparts excellent water resistance to the skin, and has high durability against skin, have.
  • a silicone water-type cosmetic composition for ultraviolet screening which is excellent in water resistance and has an improved ultraviolet shielding effect by solving the problem of solubility and formulation stability of bis-ethylhexyloxyphenol methoxyphenyltriazine have.
  • Fig. 1 (b) is a SEM photograph of the microparticles of the present invention (scale bar 2 m)
  • FIG. 2 (a) is a photograph (optical 200 times) of the microparticles of the present invention dispersed in butylene glycol (BG) by an optical microscope,
  • FIG. 2 (b) is a photograph (micrograph of polarized light 200 times) of the microparticles of the present invention dispersed in butylene glycol (BG) by an optical microscope,
  • FIG. 2 (c) is a photograph (optical 200 times) of the microparticles of the present invention dispersed in phenyltrimethicone observed with an optical microscope,
  • Example 3 (a) is a photograph (optical 200 times) of the cosmetic composition of Example 1 according to the present invention observed with an optical microscope
  • FIG. 3 (b) is a photograph (200-fold polarized light) of the cosmetic composition of Example 1 according to the present invention observed under an optical microscope,
  • Example 4 (a) is a photograph (optical 200 times) of the cosmetic composition of Example 2 according to the present invention observed with an optical microscope
  • Example 4 (b) is a photograph (200-fold polarized light) of the cosmetic composition of Example 2 according to the present invention observed under an optical microscope,
  • FIG. 5 (b) is a photograph (optical spectrum 200 times) of the cosmetic composition of Comparative Example 1 according to the present invention observed with an optical microscope,
  • FIG. 6 (b) is a photograph (200-fold polarized light) of the cosmetic composition of Comparative Example 2 according to the present invention observed under an optical microscope,
  • Example 7 (a) is a photograph (optical 200 times) of the cosmetic composition of Example 3 according to the present invention observed with an optical microscope
  • FIG. 7 (b) is a photograph (200-fold polarized light) of the cosmetic composition of Example 3 according to the present invention observed under an optical microscope,
  • Fig. 8 is a graph showing the result of evaluation of feeling on application of each sample of Example 3 and the w / s cream control group as a result of sensory evaluation according to the present invention
  • Fig. 10 shows a total sensory evaluation result according to the present invention.
  • silicone heavy water type means an emulsion having a continuous phase of an oil containing silicone oil as its main component and having a dispersed phase containing water therein. That is, the silicone heavy water type cosmetic composition means an emulsion in which an inner aqueous phase containing water is dispersed on an outer oil phase containing a silicone oil.
  • outer phase as used herein means a continuous phase containing silicone oil as a main component and may have the same meaning as a traumatic phase or a silicone phase
  • inner phase means a dispersed phase containing water , And can be synonymous with an award.
  • HLB Hydrophilic Lipophilic Balance
  • bis-ethylhexyloxyphenol methoxyphenyltriazine has to be dissolved in an oil having a high polarity such as an alkylbenzoate to be applied to an oil phase, and the solubility in a silicone oil is very low, Even if applied, the ultraviolet blocking effect was insignificant.
  • the present inventors have solved the problems of bis-ethylhexyloxyphenol methoxyphenyl triazine (BEMT), which has difficulty in application due to its solubility problem despite having a high ultraviolet shielding effect, And the methods applicable to the formulations of the embodiments have been deepened.
  • BEMT bis-ethylhexyloxyphenol methoxyphenyl triazine
  • silicone water-type cosmetic composition capable of uniformly dispersing bis-ethylhexyloxyphenol methoxyphenyltriazine in a formulation and effectively providing an SPF boosting effect by scattering ultraviolet rays have.
  • the cosmetic composition of the silicone water-repellent type according to the present invention is a formulation having an optimal formulation capable of simultaneously providing a feeling of use thereof, and provides a feeling of use different from that of a conventional emulsion formulation.
  • the present invention provides a new form of formulation in which bis-ethylhexyloxyphenol methoxyphenyltriazine can be used stably in various silicone formulations.
  • a cosmetic composition of the silicone water type according to one aspect of the present invention may comprise microparticles comprising bis-ethylhexyloxyphenol methoxyphenyltriazine.
  • the cosmetic composition of the silicone heavy water type uses bis-ethylhexyloxyphenol methoxyphenyltriazine having a very low solubility in silicone oil, the surface of the microparticles or the external surface of the composition
  • the problem of solubility of bis-ethylhexyloxyphenol methoxyphenyltriazine was solved by effectively suppressing the phenomenon of precipitation of bis-ethylhexyloxyphenol methoxyphenyltriazine into crystals.
  • the microparticles contain bis-ethylhexyloxyphenol methoxyphenyltriazine in an amount of 20% by weight or more based on the total weight of the microparticles It is possible that it is doing. At this time, the microparticles may contain only bis-ethylhexyloxyphenol methoxyphenyltriazine alone in the particles.
  • microparticles contain the above-mentioned content of bis-ethylhexyloxyphenol methoxyphenyltriazine, they have excellent optical stability and are stably dispersed in the silicone trauma to realize an excellent ultraviolet blocking effect.
  • microparticles may have a hemispherical particle shape.
  • the cosmetic composition of the silicone water type according to an embodiment of the present invention includes a microparticle having a hemispherical particle shape, thereby providing a feeling of use differentiated from the spherical microparticle, providing superior endurance with improved adhesion, And the total penetration volume is excellent in the ability to absorb sebum.
  • the average diameter of the microparticles may be in the range of 1 to 10 mu m, but is not limited thereto.
  • the spherical microparticles are provided with a distinctive feeling of use, and the ultraviolet ray shielding effect is enhanced by imparting excellent endurance with high adhesion.
  • the microparticles may be stably dispersed on the silicon surface, and the microparticles may preferably have an average diameter in the range of 1 to 8 mu m, more preferably in the range of 2 to 6 mu m But is not limited thereto.
  • the microparticles may contain bis-ethylhexyloxyphenol methoxyphenyltriazine homogeneously in the inner matrix of the polymer particles.
  • the homogeneity may mean that the bis-ethylhexyloxyphenol methoxyphenyltriazine is uniformly mixed in the polymer matrix in a molecular manner.
  • the microparticles may be prepared by dispersing and polymerizing using an oil phase simultaneously containing bis-ethylhexyloxyphenol methoxyphenyltriazine, a polymerizable monomer and a polyfunctional crosslinking monomer. That is, the microparticles may be such that bis-ethylhexyloxyphenol methoxyphenyl triazine is homogeneously contained in the internal matrix of the polymer particles.
  • the microparticles may be hemispherical particles.
  • a hemispherical shape can be specifically formed according to the use amount of bis-ethylhexyloxyphenol methoxyphenyltriazine, which is an organic UV-blocking agent, in the dispersion polymerization for producing microparticles alone .
  • the microparticles may contain 20 wt% or more of bis-ethylhexyloxyphenol methoxyphenyltriazine as described above.
  • the microparticles prepared by the dispersion polymerization may contain 24 to 30% by weight of the bis-ethylhexyloxyphenol methoxyphenyltriazine, more specifically 24.5 to 28.5% by weight have.
  • hemispherical microparticles can be formed to improve the desired effect, but the present invention is not limited thereto.
  • the microparticles prepared by the dispersion polymerization may be used in an amount of 0.1 to 100 parts by weight based on 100 parts by weight of the polymerizable monomer, and the amount of the microparticles may vary depending on the purpose. Needless to say, the amount of bis-ethylhexyloxyphenol methoxyphenyltriazine to be used can be appropriately adjusted for the particle shape to be implemented.
  • the polyfunctional crosslinking monomer may be used in an amount of 1 to 50 parts by weight, more specifically 1 to 25 parts by weight, based on 100 parts by weight of the polymerizable monomer, but is not limited thereto.
  • the polymerizable monomer is not limited as long as it is a radically polymerizable monomer capable of copolymerizing with a polyfunctional crosslinking monomer described later, and specifically, it may be a radically polymerizable monomer containing one ethylene group.
  • aromatic vinyl monomers such as styrene, methylstyrene, ethylstyrene, fluorostyrene, chlorostyrene, and vinyltoluene; Acrylates such as methyl (meth) acrylate, ethyl (meth) acrylate, butyl (meth) acrylate, octyl (meth) acrylate, stearyl Acrylate-based vinyl monomers; And the like.
  • the above-mentioned one or two or more radically polymerizable monomers may be used.
  • the multifunctional crosslinking monomer is not limited as long as it is a monomer capable of crosslinking the polymerizable monomer, specifically, it may be a crosslinking monomer containing at least two ethylene groups.
  • ethylene glycol dimethacrylate diethylene glycol dimethacrylate
  • triethylene glycol dimethacrylate trimethylene propane trimethacrylate
  • 1,3-butanediol dimethacrylate trimethylene propane trimethacrylate
  • 1,3-butanediol dimethacrylate 1,3-butanediol dimethacrylate
  • Hexanediol dimethacrylate tri (meth) acrylate, and the like.
  • one or more of the above-mentioned polyfunctional crosslinking monomers may be used.
  • the cosmetic composition of the silicone water type according to an embodiment of the present invention may contain the microparticles in an amount of 1 to 35% by weight, specifically 5 to 30% by weight, more specifically, By weight and 5 to 15% by weight.
  • the cosmetic composition of the silicone water type may include bis-ethylhexyloxyphenol methoxyphenyltriazine in a maximum amount of 10% by weight based on the total weight of the composition.
  • the cosmetic composition of the silicone water type according to one embodiment of the present invention may further comprise a phenylbenzimidazole-based compound and a cyclodextrin-based compound in the aqueous phase.
  • the phenylbenzimidazole-based compound is one of the organic UV-ray blocking agents contained in the water phase.
  • the pH of the formulation is adjusted to an appropriate range to inhibit crystal precipitation.
  • the W / S formulation based on silicon the phenylbenzimidazole-based compound precipitated and thus it was difficult to apply to the aqueous phase.
  • the cosmetic composition of the silicone water-repellent type according to one embodiment of the present invention effectively inhibits the problem (for example, crystal precipitation) by using the combination of the above-mentioned microparticles and the phenylbenzimidazole-based compound Respectively.
  • the simultaneous use of a cyclodextrin compound can more effectively inhibit crystal precipitation, and even if a phenylbenzimidazole-based compound is partially precipitated in an aqueous phase, it can be reliably reused in an aqueous phase.
  • the phenylbenzimidazole-based compound and the cyclodextrin-based compound may be contained in a weight ratio of 1: 0.1 to 1:10.
  • the phenylbenzimidazole-based compound and the cyclodextrin-based compound may be contained in a weight ratio of 1: 1 to 1: 2, more specifically, 1: 1.5 to 1: 2, It is preferable from the viewpoint that the formulation stability can be further improved as compared with the case where it is satisfied.
  • the pH of the composition may be at least 7.5, and more preferably 7.5 to 9, more specifically 7.5 to 8.5.
  • composition when the composition satisfies the above-mentioned weight ratio of the phenylbenzimidazole-based compound and the cyclodextrin-based compound and satisfies the pH range of 7.5 or more, it is possible to suppress the crystal precipitation of the phenylbenzimidazole- In view of being able to plan.
  • the phenylbenzimidazole-based compound is one of water-soluble organic UV-blocking agents, and examples thereof include phenylbenzimidazole sulfonic acid, potassium phenylbenzimidazole sulfonate, sodium phenylbenzimidazole sulfonate Sodium Phenylbenzimidazole Sulfonate) and TEA-Phenylbenzimidazole Sulfonate (TEA-Phenylbenzimidazole Sulfonate).
  • the above-mentioned one or two or more phenylbenzimidazole-based compounds may be used, but the present invention is not limited thereto.
  • the phenylbenzimidazole-based compound may be contained in an amount of 0.1 to 10 wt% based on the total weight of the composition, specifically 0.5 to 4.5 wt% %, More specifically 0.5 to 2.5% by weight, based on the total weight of the composition.
  • the cyclodextrin-based compound prevents crystallization of the phenylbenzimidazole-based compound and provides for improved formulation stability.
  • examples thereof include alpha-cyclodextrin, beta-cyclodextrin, gamma-cyclodextrin, hydroxypropyl beta-cyclodextrin , Carboxymethyl cyclodextrin, methyl carboxymethyl cyclodextrin, aminocyclodextrin, branched cyclodextrin with addition of glucose, and cyclodextrin polymers.
  • the above-mentioned one or more cyclodextrin-based compounds may be used, but the present invention is not limited thereto.
  • the phenylbenzimidazole-based compound and the cyclodextrin-based compound are included in the aqueous phase.
  • the cyclodextrin compound effectively inhibits crystal precipitation of the phenylbenzimidazole-based compound contained in the aqueous phase, and when satisfying a predetermined weight ratio and satisfying the optimum pH range of the composition, the phenylbenzimidazole-based compound It is possible to completely inhibit crystallization of the compound and provide a more stable formulation.
  • the amount of the bis-ethylhexyloxyphenol methoxyphenyltriazine and the phenylbenzimidazole-based compound used in the silicone-type water-based cosmetic composition according to an embodiment of the present invention may satisfy the following relational expression (1).
  • A is the amount (g) of bis-ethylhexyloxyphenol methoxyphenyltriazine used,
  • organic-based ultraviolet screening agents i.e., bis-ethylhexyloxyphenol methoxyphenyltriazine and phenylbenzimidazole-based compounds
  • UV A, UV B, and UV C can be realized by introducing the ultraviolet rays.
  • the cosmetic composition of the silicone water type according to an embodiment of the present invention is characterized in that it contains substantially no polar oil or a trace amount thereof for dissolving bis-ethylhexyloxyphenol methoxyphenyltriazine.
  • the polar oil includes at least one polar functional group selected from a carboxyl group (COO), a ketone group (CO) and a hydroxyl group (OH), and examples thereof include cetyl ethylhexanoate, octyldodecyl myristate, Di-C 12-13 alkyl maleate, pentaerythritol tetraisostearate, pentaerythritol tetraethyl hexanoate, diisostearyl maleate, isopropyl palmitate, C 12-15 alkyl benzoate, dicaprylic carbonate, Dicaprylyl ether, 2-octyldodecanol, and the like.
  • COO carboxyl group
  • CO ketone group
  • OH hydroxyl group
  • the polar oil may be included in an amount of 0 to 1% by weight based on the total weight of the composition, specifically 0 to 0.5% by weight, and more specifically 0 to 0.1% by weight. It is not.
  • the cosmetic composition of the silicone water type according to one embodiment of the present invention is characterized in that the microparticles containing bis-ethylhexyloxyphenol methoxyphenyltriazine are dispersed stably and at the same time, bis-ethylhexyl From the viewpoint of not generating oxyphenol methoxyphenyltriazine, it is preferable to use a PEG-containing silicone surfactant.
  • PEG-containing silicone surfactant examples include PEG / PPG-18/18 dimethicone, PEG-30Dipolyhydroxystearate, PEG-7Dimethicone, PEG-10 Dimethicone, PEG-10 Dimethicone, Cyclopentasiloxane / PEG.PPG-19.19 Dimecicone / PEG.PPG-19.19 Dimethicone, Sorbitan Isostearate ), Lauryl PEG.PPG-18.18 methicone, cetyl PEG.PPG-10.1 dimethicone, lauryl PEG-9 polydimethylsiloxy ethyl dimethicone And Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone.
  • one or more of the exemplified PEG-containing silicone surfactants may be used, but the present invention is not limited thereto.
  • the PEG-containing silicone surfactant may be a nonionic surfactant having a hydrophilic-lipophilic group balance (HLB) of 1 to 6.
  • HLB hydrophilic-lipophilic group balance
  • the amount of the PEG-containing silicone surfactant used in the silicone-type water-based cosmetic composition according to an embodiment of the present invention may be appropriately adjusted depending on the kind and content of the silicone oil.
  • a PEG-containing silicone surfactant may be used based on the total weight of the composition, specifically 1 to 8% by weight, more specifically 3 to 6% by weight of a PEG- But is not limited thereto.
  • the cosmetic composition of the silicone water type according to an embodiment of the present invention may contain 1 to 4.5% by weight of the bis-ethylhexyloxyphenol methoxyphenyltriazine based on the total weight of the composition, By weight, and 1 to 4% by weight, more specifically, 1.5 to 3.5% by weight.
  • the cosmetic composition of the silicone water type according to one embodiment of the present invention contains not more than 15% by weight of an organic UV-blocking agent comprising bis-ethylhexyloxyphenol methoxyphenyltriazine,
  • the UV blocking index of the composition may be at least 30.
  • UV cutoff index (minimum erythema amount of the skin part applied with the cosmetic composition of the silicone water type) / (minimum erythema amount of the skin part not coated with the silicone water type cosmetic composition)
  • the cosmetic composition of the silicone heavy water type according to the present invention comprises 4.5 wt% of the maximum bis-ethylhexyloxyphenol methoxyphenyltriazine, and the organic base including the bis-ethylhexyloxyphenol methoxyphenyltriazine
  • the ultraviolet screening index of the composition calculated by the formula 1 may be 10 to 50.
  • the ultraviolet screening index of the composition may be 20 to 50, more specifically,
  • the ultraviolet barrier index of the composition may be from 30 to 50.
  • the cosmetic composition of the silicone heavy water type may include at least one member selected from the group consisting of dimethicone, cyclomethicone, phenyltrimethicone, polydimethylsiloxane, methylphenylpolysiloxane, methylcyclopolysiloxane, octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, Dodecamethylcyclohexasiloxane, tetradecamethylhexasiloxane, octamethyltrisiloxane, and the like, and the like.
  • the silicone oil may be contained in an amount of 15 to 60% by weight based on the total weight of the composition, specifically 15 to 50% by weight, and more specifically 20 to 40% by weight. It is not.
  • the composition comprises a balance of water.
  • the cosmetic composition of the silicone water type according to an embodiment of the present invention may further include an organic UV-blocking agent and an inorganic UV-blocking agent, depending on the purpose, and may further contain a moisturizing component, an aging agent, a pH adjusting agent, Flavoring agents, preservatives, soothing accelerators, and the like.
  • the organic UV blocking agent, the inorganic UV blocking agent and the additives may be included in the range of 0.01 to 20% by weight based on the total weight of the composition, but the present invention is not limited thereto.
  • the cosmetic composition of the silicone water-repellent type including the organic ultraviolet screening agent according to an example of the present invention will be described in more detail with reference to examples. It should be understood, however, that the invention is not limited to the disclosed embodiments, but, on the contrary, is intended to cover various modifications and equivalent arrangements included within the spirit and scope of the invention.
  • the unit of the component not specifically described in the specification may be g or% by weight based on the total composition.
  • the amount of ultraviolet light radiated from the solar simulator lamp to the test site was adjusted to 20 to 100 mj / cm 2 and irradiated to the back region of the subject.
  • Minimal Erythema Dosa (MED) was confirmed after 24 hours of UV irradiation.
  • the test was conducted by irradiating the ultraviolet radiation dose to the subject's MED standard (SPF 50) and gradually increasing the dose of ultraviolet radiation.
  • the minimum erythema was determined after 24 hours of ultraviolet irradiation, and the ultraviolet blocking effect was calculated according to the following equation (1). The results are shown in Table 2 below.
  • UV cutoff index (minimum erythema amount of skin part applied with cosmetic composition of silicone heavy type) / (minimum erythema amount of skin part not applied silicone cosmetic type cosmetic composition, MED)
  • Example 2 The sensory evaluation of each sample (Example) was evaluated as feeling of use after application and application.
  • the sensory evaluation was carried out by a general questionnaire survey method of five men and women participating in the evaluation, and the results are shown in FIG. 8 to FIG. 10.
  • the w / s cream prepared using the ingredients shown in Table 3 below was used as a control.
  • the questionnaire was confirmed by a 10-point scale (-5 to 5 points).
  • each sample was a test for the application of each sample (Example) was carried out. Specifically, the right and left sides of each panel of each panel (male and female) were washed with soap, and the skin was adapted at a temperature of about 20 ° C and a humidity of about 40%. The test area was defined as 4 x 3 cm square on the left and right sides of the bottom of the hatchback. The hatching was applied after each application, and the first reading was performed 30 minutes later. After 96 hours Secondary reading was performed later. To determine the intensity of the skin irritation of each sample, weights were assigned according to the degree of positive reactions of the skin, and the skin irritation of each sample was visually determined. The results are shown in Table 5 below.
  • Skin reaction rate ( ⁇ grade ⁇ number of reaction ⁇ 100) / ⁇ 4 (maximum grade) ⁇ n (total number of people) ⁇ 2 (score of judgment) ⁇
  • MMA methyl methacrylate
  • ethylene glycol dimethacrylate ethylene glycol dimethacrylate
  • BEMT bis-ethylhexyloxyphenol methoxyphenyltriazine
  • aqueous phase was added to the emulsifier, dispersion polymerization was carried out for 30 minutes using an emulsifier, the temperature was elevated, and the reaction was carried out at 50 ° C for 15 hours.
  • the hemispherical microparticles obtained by the above method were used to measure the oil absorption (measured in a room controlled at room temperature (23 ⁇ ⁇ ) in accordance with the method of measuring the oil absorption amount described in JIS K 5101-13-1).
  • the hemispherical microparticles obtained by the above method had an oil absorption of 0.888 ml / g and a total intrusion volume of 1.37 ml / g. This corresponds to an oil absorption of 150% or more and a total penetration volume of 210% or more of conventional PMMA spherical particles.
  • hemispherical microparticles obtained by the above method can be stably dispersed in a polyol (e.g., butylene glycol) or a silicone oil (e.g., phenyltrimethicone), and even during storage, bis-ethylhexyloxyphenol methoxyphenyl tri Precipitation of azine was not found (see Fig. 2).
  • a polyol e.g., butylene glycol
  • silicone oil e.g., phenyltrimethicone
  • MMA methyl methacrylate
  • BEMT bis-ethylhexyloxyphenol methoxyphenyltriazine
  • a silicone water-type cosmetic composition was prepared with the composition shown in Table 1 below.
  • the components of the oily phase were mixed and uniformly dispersed and dissolved.
  • the components of the water phase were mixed and dissolved, and the solution was emulsified using a homogenizer while being added to warmed oily components to prepare a silicone water type cosmetic composition.
  • a silicone water-type cosmetic composition was prepared using the composition shown in Table 2 below and in the same manner as in the above example.
  • the cosmetic composition of the silicone water type according to the present invention is characterized in that when observing by optical and polarizing microscope, the phenylbenzimidazole-based bis-ethylhexyloxyphenol methoxyphenyltri It was confirmed that a very stable formulation can be maintained without precipitating crystals into crystals.
  • the silicone water-type cosmetic composition according to the present invention can be combined with a phenylbenzimidazole-based compound, which is one of the organic UV-
  • a phenylbenzimidazole-based compound which is one of the organic UV-
  • synergies can be added to the SPF index.
  • the phenylbenzimidazole-based compound applied to the water phase can be more stably applied to the formulation without the precipitation.
  • the cosmetic composition of the silicone heavy water type according to the present invention can simultaneously provide a feeling of feeling providing a feeling of residual and thickness with a feeling of use that is light and non-sticky and excellent adhesion.

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Abstract

La présente invention concerne une composition cosmétique de type eau dans silicone comprenant un agent d'écran solaire organique. La présente invention peut fournir une composition cosmétique de type eau dans silicone comprenant de la bis-éthylhexyloxyphénol méthoxyphényl triazine, qui n'était auparavant pas applicable à des formulations de silicone en raison de problèmes de solubilité.
PCT/KR2018/013778 2017-11-16 2018-11-13 Composition cosmétique de type eau dans silicone comprenant un agent d'écran solaire organique Ceased WO2019098637A2 (fr)

Priority Applications (2)

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SG11202004334TA SG11202004334TA (en) 2017-11-16 2018-11-13 Water-in-silicone type cosmetic composition comprising organic sunscreen agent
CN201880073976.8A CN111432789A (zh) 2017-11-16 2018-11-13 包含有机类防紫外线剂的硅包水型的化妆料组合物

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KR20170152721 2017-11-16
KR10-2017-0152721 2017-11-16
KR1020180096027A KR102587916B1 (ko) 2017-11-16 2018-08-17 유기계 자외선 차단제를 포함하는 실리콘중수 타입의 화장료 조성물
KR10-2018-0096027 2018-08-17

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JP3160398B2 (ja) * 1992-12-03 2001-04-25 松本油脂製薬株式会社 固型粉末化粧料
US7914772B2 (en) * 2008-06-30 2011-03-29 Conopco, Inc. Sunscreen composite particles dispersed in water-in-oil cosmetic compositions
KR101327826B1 (ko) * 2011-11-22 2013-11-11 주식회사 제닉 유중수 형태의 투명한 자외선 차단 조성물
WO2015195546A1 (fr) * 2014-06-17 2015-12-23 TopGeniX, Inc. Formulations topiques de protection contre les uv
KR101833612B1 (ko) * 2016-03-30 2018-02-28 선진뷰티사이언스(주) 다량의 유기계 자외선 차단제를 함유하는 고분자 복합입자 및 그의 제조방법

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