WO2019100903A1 - Ensemble micro-dispositif élastique et instrument d'amélioration de pénétration l'utilisant - Google Patents

Ensemble micro-dispositif élastique et instrument d'amélioration de pénétration l'utilisant Download PDF

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Publication number
WO2019100903A1
WO2019100903A1 PCT/CN2018/112011 CN2018112011W WO2019100903A1 WO 2019100903 A1 WO2019100903 A1 WO 2019100903A1 CN 2018112011 W CN2018112011 W CN 2018112011W WO 2019100903 A1 WO2019100903 A1 WO 2019100903A1
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WO
WIPO (PCT)
Prior art keywords
elastic
seat
assembly
permeation
motor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2018/112011
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English (en)
Chinese (zh)
Inventor
徐百
吴国林
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suzhou Nanomed Biomed Co Ltd
Original Assignee
Suzhou Nanomed Biomed Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suzhou Nanomed Biomed Co Ltd filed Critical Suzhou Nanomed Biomed Co Ltd
Publication of WO2019100903A1 publication Critical patent/WO2019100903A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests

Definitions

  • the present invention relates to the field of percutaneous delivery devices, and in particular, to an elastic micro device assembly and a permeation device using the same.
  • Nano-microneedle is a kind of micro-needle that opens the skin tube through nanotechnology.
  • the needle is similar to a small wafer square, which is covered with dense, small and invisible small needles. Press this small square on the skin. , the drug can enter the epidermis, and people have almost no feeling.
  • Nano-wafer is a special nano-infiltration tool developed according to human skin structure, which is carved from single crystal silicon through nanotechnology.
  • the surface of the nanochip is a series of microneedle arrays that open the outermost stratum corneum of the skin without damaging the dermis and greatly increasing the ability of the delivery medium to penetrate the skin's epidermis.
  • the biocompatibility of single crystal silicon also ensures the safety of nanocrystals during use.
  • Chinese patent 0X20469924611 uses a beauty instrument to drive nano-micro needles and nano-chips to move up and down the skin surface, but the force of such beauty instruments is difficult to control at a small force, thereby making nano-micro needles and nanochips and skin It is stressed when it comes into contact, and it is easy to sting the skin when used for a long time. Therefore, directly driving the nano-needle and nano-wafer through the beauty instrument can promote the penetration, but the pressure on the skin is large, and it is easy to cause a certain degree of damage.
  • the existing cosmetic permeation instrument generally adopts a column structure design, such as a luminous electric microneedle cosmetic permeation instrument disclosed in Chinese Patent No. 0204045141 II, including a piston needle and a driving piston needle.
  • the reciprocating driving device is disposed inside the body casing, and the piston needle comprises a fixing sleeve and a movable needle in the fixing sleeve, and the fixing sleeve is connected with the end of the body casing.
  • the working direction of the piston needle is in line with the drive unit and the body housing.
  • the cosmetic permeation device of such a structure is more suitable for use in a beauty salon or the like operated by another person, such as a user himself operating at home, holding a columnar beauty permeation instrument, and holding the direction and work.
  • the direction is on the straight line, the hand needs to pay a lot of grip, long-term operation will bring hand muscle fatigue ⁇ 0 2019/100903 ⁇ (: 170 ⁇ 2018/112011 labor, not conducive to the user experience.
  • An elastic micro device assembly includes a hollow pressure receiving member, a hollow inner portion of the pressure receiving member is provided with a vibration seat, and an upper surface of the vibration seat is provided with a micro device for penetrating only the stratum corneum of the skin.
  • the vibration seat is fixedly connected to the inner surface of the pressure receiving member by a plurality of elastic arms; the pressure receiving member is provided with a connecting portion connected to the penetration enhancer.
  • the micro device penetrates the stratum corneum of the skin to a length of between 4 micrometers and 2000 micrometers.
  • the micro device is a nano microneedle or a nanochip.
  • the elastic arm and the pressure receiving member and the vibration seat are integrally formed plastic parts.
  • the shape of the elastic arm includes a type II, a V shape, an M shape or a spiral shape.
  • the elastic arm has a thickness of 0.1 mm -1 mm.
  • a permeation device comprising the above described elastic micro device assembly, an outer casing detachably coupled to the elastic micro device assembly, a power supply assembly disposed inside the outer casing, and a motor electrically coupled to the power supply assembly
  • One end of the shaft is drivingly coupled to the motor, and the other end is pierced from the outside of the housing and abuts against the vibrating seat of the elastic micro device assembly.
  • the power component includes a power source body, a circuit board connected to the power source body, and a switch electrically connected to the circuit board; the motor is electrically connected to the circuit board.
  • the power source body is a rechargeable power source
  • the circuit board is electrically connected to the charging port.
  • the housing is provided with a switch hole and a charging port corresponding to the switch and the charging port.
  • the motor includes a motor body, and an eccentric mechanism connected to the motor body, and the motor body drives the shaft to reciprocate through the eccentric mechanism.
  • the upper end of the outer casing is an operating end, and the lower end is a handle end; the outer side of the operating end is provided with a groove seat, and the groove seat is provided with a shaft hole for inserting the shaft And at least one of the limiting card slots; the recessed seat is detachably coupled to the elastic micro device assembly, and the connecting portion provided on the pressure receiving member of the elastic micro device assembly is The buckle corresponding to the limit card slot is engaged with the limit card slot.
  • a sealing member is disposed at a position corresponding to the inner side of the operating end, and a through hole for inserting the shaft is disposed on the sealing member, and the sealing member further A protrusion is disposed, and the groove seat is provided with a groove that cooperates with the protrusion.
  • the outer casing includes an upper casing and a lower casing that are detachably fixedly coupled, and a joint of the upper casing and the lower casing is provided with an anti-slip ring and a hand strap.
  • the outstanding effect of the utility model is: an elastic micro-device assembly of the utility model, wherein the vibration seat is converted into the elastic deformation potential energy of the elastic arm after being subjected to the thrust, and the elastic deformation potential energy of the elastic arm is converted into the vibration of the vibration seat.
  • the kinetic energy causes the micro device to vibrate. Since the vibration of the micro device is driven by the elastic force of the elastic arm, the pressure generated by the beauty instrument directly in the prior art is small and easy to control, so that no damage is caused to the skin.
  • the elastic micro device assembly of the utility model is integrally formed, has a simple structure, simplifies the process flow, saves production cost, and is advantageous for industrial production.
  • the permeation enhancer of the utility model converts the vibration direction of the shaft into a direction perpendicular to the hand direction by adopting the eccentric mechanism of the motor, thereby improving the operation convenience and solving the problem of the user's hand fatigue.
  • Embodiment 1 is a schematic structural view of Embodiment 1 of the present invention.
  • Embodiment 1 of the present invention is a second schematic structural view of Embodiment 1 of the present invention.
  • Embodiment 3 is a third schematic structural view of Embodiment 1 of the present invention.
  • FIG. 4 is an exploded view of the structure of Embodiment 2 of the present invention.
  • an elastic micro device assembly 13 of the present embodiment includes a hollow pressure receiving member 131.
  • the hollow interior of the pressure receiving member 131 is provided with a vibration seat 132, and the vibration seat 132 is mounted thereon.
  • the surface is provided with a micro device 133 for penetrating only the stratum corneum of the skin, and the vibration seat 132 is fixedly connected with the inner surface of the pressure receiving member 131 through a plurality of elastic arms 134; the pressure receiving member 131 is provided with a permeation device.
  • the micro device 133 penetrates the stratum corneum of the skin to a length of between 4 micrometers and 2000 micrometers.
  • the micro device 133 is a nano microneedle or a nanochip.
  • the elastic arm 134 is integrally formed with the pressure receiving member 131 and the vibrating seat 132.
  • the shape of the resilient arm 134 includes a U-shape, a V-shape, an M-shape, or a spiral shape.
  • the elastic arm 134 has a thickness of 0.1 mm - 1 mm.
  • the vibration seat 132 is transformed into the elastic deformation potential energy of the elastic arm 134 after being thrusted, and the elastic deformation potential energy of the elastic arm 134 is converted into the dynamic vibration B that drives the vibration seat 132 to vibrate. Therefore, the micro device 133 generates vibration. Since the vibration of the micro device 133 is driven by the elastic force of the elastic arm 134, the pressure generated by the beauty instrument directly in the prior art is small and easy to control, so that no damage is caused to the skin.
  • the elastic micro device assembly 13 of the present embodiment is integrally formed, has a simple structure, simplifies the process flow, saves production costs, and is advantageous for industrial production.
  • a permeation device of the embodiment includes the elastic micro device assembly 13 of the embodiment 1, the outer casing detachably connected to the elastic micro device assembly 13, and the power component disposed inside the outer casing. And a motor electrically connected to the power supply assembly, one end of the shaft 1 is drivingly coupled to the motor, and the other end is pierced from the outside of the outer casing and abuts against the vibrating seat 132 of the elastic micro device assembly 13.
  • the power supply assembly comprises a power supply body 2, a circuit board 3 connected to the power supply body 2, and a switch 4 electrically connected to the circuit board 3; the motor is electrically connected to the circuit board 3.
  • the power body 2 is a rechargeable power source, on the circuit board 3 ⁇ 0 2019/100903 ⁇ (:170 ⁇ 2018/112011
  • the electrical connection has a charging port 5.
  • the housing has a switch hole 6 and a charging port 7 corresponding to the switch 4 and the charging port 5
  • the motor includes a motor body 8, and an eccentric mechanism 9 connected to the motor body 8, and the motor body 8 drives the shaft 1 to reciprocate by the eccentric mechanism 9.
  • the upper end of the outer casing is an operating end, and the lower end is a handle end; the outer side of the operating end is provided with a groove seat 10, and the groove seat 10 is provided with a shaft hole 11 for inserting the shaft 1 and two limit card slots
  • An elastic micro-device assembly 13 is detachably coupled to the recessed seat 10, and the connecting portion 135 of the pressure-receiving member 131 of the elastic micro-device assembly 13 is a buckle 14 corresponding to the limiting slot 12, The buckle 14 is engaged with the limit card slot 12.
  • the inner side of the operating end is provided with a sealing member 15 at a position corresponding to the groove holder 10.
  • the sealing member 15 is provided with a through hole 16 for penetrating the shaft 1, and the sealing member 15 is further provided with a protrusion 17 and a concave portion.
  • a groove 18 that cooperates with the projection 17 is formed in the housing 10.
  • the outer casing includes an upper casing 19 and a lower casing 20 that are detachably fixedly coupled, and an anti-slip ring 21 and a hand strap 22 are provided at the joint of the upper casing 19 and the lower casing 20.
  • the vibration direction of the shaft 1 is converted into a direction perpendicular to the hand-held direction by using the eccentric mechanism 9 of the motor, thereby improving the convenience of operation and solving the fatigue of the user.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Informatics (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Percussion Or Vibration Massage (AREA)

Abstract

L'invention concerne un ensemble micro-dispositif élastique (13), comprenant un élément de support de pression (131) creux, un bloc de vibration (132) étant disposé dans l'élément de support de pression (131), une unité de micro-aiguille (133) destinée à pénétrer uniquement dans la couche cornée de la peau est disposée sur une surface supérieure du bloc de vibration (132); le bloc de vibration (132) est relié de manière fixe à une surface interne de l'élément de support de pression (131) au moyen de plusieurs bras élastiques (134); et l'élément de support de pression (131) est pourvu d'une partie de liaison (135) reliée à l'instrument d'amélioration de pénétration. L'invention concerne en outre un instrument d'amélioration de pénétration ayant l'ensemble micro-dispositif élastique (13).
PCT/CN2018/112011 2017-11-27 2018-10-26 Ensemble micro-dispositif élastique et instrument d'amélioration de pénétration l'utilisant Ceased WO2019100903A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201721604028.1 2017-11-27
CN201721604028.1U CN209500517U (zh) 2017-11-27 2017-11-27 一种弹性微型装置组件以及应用该组件的促渗仪

Publications (1)

Publication Number Publication Date
WO2019100903A1 true WO2019100903A1 (fr) 2019-05-31

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2018/112011 Ceased WO2019100903A1 (fr) 2017-11-27 2018-10-26 Ensemble micro-dispositif élastique et instrument d'amélioration de pénétration l'utilisant

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CN (1) CN209500517U (fr)
WO (1) WO2019100903A1 (fr)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090198189A1 (en) * 2006-04-20 2009-08-06 3M Innovative Properties Company Device for applying a microneedle array
WO2014058746A1 (fr) * 2012-10-10 2014-04-17 3M Innovative Properties Company Applicateur régulé par une force pour appliquer un dispositif à micro-aiguille sur la peau
CN204017141U (zh) * 2014-08-15 2014-12-17 赵明知 一种发光的电动微针美容促渗仪
CN205127116U (zh) * 2015-09-15 2016-04-06 微邦科技股份有限公司 可替换式微针敷片的振动结构

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090198189A1 (en) * 2006-04-20 2009-08-06 3M Innovative Properties Company Device for applying a microneedle array
WO2014058746A1 (fr) * 2012-10-10 2014-04-17 3M Innovative Properties Company Applicateur régulé par une force pour appliquer un dispositif à micro-aiguille sur la peau
CN204017141U (zh) * 2014-08-15 2014-12-17 赵明知 一种发光的电动微针美容促渗仪
CN205127116U (zh) * 2015-09-15 2016-04-06 微邦科技股份有限公司 可替换式微针敷片的振动结构

Also Published As

Publication number Publication date
CN209500517U (zh) 2019-10-18

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