WO2019138433A1 - Procédé de fabrication d'un tube à essai destiné à être utilisé avec des pipettes d'aspiration ou de sédimentation et tube à essai ainsi obtenu - Google Patents

Procédé de fabrication d'un tube à essai destiné à être utilisé avec des pipettes d'aspiration ou de sédimentation et tube à essai ainsi obtenu Download PDF

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Publication number
WO2019138433A1
WO2019138433A1 PCT/IT2018/000002 IT2018000002W WO2019138433A1 WO 2019138433 A1 WO2019138433 A1 WO 2019138433A1 IT 2018000002 W IT2018000002 W IT 2018000002W WO 2019138433 A1 WO2019138433 A1 WO 2019138433A1
Authority
WO
WIPO (PCT)
Prior art keywords
test tube
wall
thickness variation
forming
tube
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IT2018/000002
Other languages
English (en)
Inventor
Roberto Guglielmo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to PCT/IT2018/000002 priority Critical patent/WO2019138433A1/fr
Publication of WO2019138433A1 publication Critical patent/WO2019138433A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5021—Test tubes specially adapted for centrifugation purposes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/02—Identification, exchange or storage of information
    • B01L2300/025—Displaying results or values with integrated means
    • B01L2300/028—Graduation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0848—Specific forms of parts of containers
    • B01L2300/0858—Side walls

Definitions

  • the present invention relates to a method of manufacturing a test tube for use with suction or sedimentation pipettes. Further, the invention relates to a test tube having an inner surface on which can safely rest the tip of a sampling pipette at a precise desired tube height.
  • test tube according to the invention is advantageously usable in stratification or sedimentation operations in liquids of different density or in suspensions.
  • the purpose of the stratifications is to separate the different components present in a solution or suspension under examination. Normally, this process is carried out after centrifugation of test tubes containing a liquid in which the different component phases are to be separated and for which a component of interest is to be taken.
  • the phases that can be observed through the transparent walls of the test tube have two visible interfaces which mark separation boundaries between the various liquid or solid components. These components or phases are subject to mixing and contamination when uncontrolled flows of liquid are created.
  • the position of the sedimentation pipette must not be too high to avoid mixing by excessive falling speed in the flow of liquid to be overlapped or so low as to get to cross an interface surface between two layers of liquid, and then inoculate the column of underlying liquids or solids.
  • the present invention aims to overcome the aforementioned drawbacks.
  • a main object of the present invention is to allow a stable and precise support of the tip of a suction or sedimentation pipette.
  • the present invention provides a method of manufacturing a test tube for use with suction or sedimentation pipettes, the test tube having a wall with an inner side, the method comprising a step of forming a spiral linear thickness variation of the tube wall on its inner side.
  • the invention provides a test tube so obtained.
  • FIG. 1 is a schematic side view of a test tube according to the invention.
  • FIG. 2 is a schematic side view of a micro test tube of the Eppendorf type according to the invention.
  • FIG. 3 is a partial schematic side view of the test tube of Figure 1, in which volumetric indications are added.
  • FIG. 1 is a schematic side view of a test tube 1 with a capacity between 15 ml and 50 ml
  • the test tube 1 has a longitudinal axis y and a wall 10 with an inner side 11 and an outer side 12.
  • the test tube 1 is closed with a cap 13. However, it may also be without a cap.
  • a spiral linear thickness variation 14 is formed in the wall 10, on its inner side 11, a spiral linear thickness variation 14 is formed.
  • longitudinal linear thickness variations are formed in the wall 10 on its inner side 11, and they identify intersection points 16 with the spiral linear thickness variation 14.
  • thickness variations in horizontal segments can be provided, generally indicated as 17, forming intersection points 18 with the spiral linear thickness variation 14.
  • the spiral linear thickness variation 14 and the longitudinal linear thickness variations 15 may be embossed or engraved, if the thickness of the test tube allows it.
  • a pipette not shown for suction or sedimentation can be supported in a stable manner at the desired height of the test tube.
  • FIG. 2 is a schematic side view of a micro test tube 2 of the Eppendorf type with a capacity between 1.5 ml and 2.0 ml
  • the micro test tube 2 has a longitudinal axis y and a wall 20 with an inner side 21 and an outer side 22.
  • the micro test tube 2 is closed with a plug 23.
  • a spiral linear thickness variation 24 is formed, which narrows downwards.
  • a longitudinal linear thickness variation 25 is formed in the wall 20, on its inner side 21, and identifies intersection points 26 with the spiral linear thickness variation 24.
  • FIG. 3 is a partial schematic side view of the test tube of Figure 1, of which the same reference numerals are used to mark equal or similar parts.
  • volumetric indications are applied, generally indicated as IV, which allow to provide information on the contents inside the test tube, possibly also in its various components.
  • the volumetric indications IV can be printed flat, embossed or engraved.
  • intersection of spiral linear longitudinal and possibly even horizontal thickness variations offers a safer support point for the tip of the suction or sedimentation pipette.
  • test tubes with a greater wall thickness
  • longitudinal, horizontal, and spiral linear thickness variations are made with deep engraving instead of with reliefs. This feature can help to modulate the velocity of fluids in deposition, sedimentation and stratification operations with greater precision.
  • test tubes can be made of the most varied materials and can also be sterile.
  • the reliefs or incisions to be produced must, except for extraordinary needs, present non-orthogona 1 angles with respect to the wall of the test piece, angles which may present component deposits after centrifugation.
  • the angles could ideally be between 45°/l35° and 225°/315° depending on the presence of spirals in relief or engraving in the test tube, but certainly also variable according to technical or operational needs.

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

L'invention concerne un procédé de fabrication d'un tube à essai destiné à être utilisé avec des pipettes d'aspiration ou de sédimentation. Le tube (1) présente une paroi (10) avec un côté intérieur (11). Le procédé comprend une étape de réalisation d'une variation d'épaisseur linéaire en spirale (14) en relief ou gravée, sur le côté interne (11) de la paroi (10) du tube à essai (1). De plus, le procédé comprend une étape de réalisation de variations d'épaisseur linéaire longitudinale (15) sur le côté interne (11) de la paroi (10) du tube à essai (1), formant des points d'intersection (16) avec la variation d'épaisseur linéaire en spirale (14). L'invention concerne également un tube à essai ainsi obtenu.
PCT/IT2018/000002 2018-01-12 2018-01-12 Procédé de fabrication d'un tube à essai destiné à être utilisé avec des pipettes d'aspiration ou de sédimentation et tube à essai ainsi obtenu Ceased WO2019138433A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/IT2018/000002 WO2019138433A1 (fr) 2018-01-12 2018-01-12 Procédé de fabrication d'un tube à essai destiné à être utilisé avec des pipettes d'aspiration ou de sédimentation et tube à essai ainsi obtenu

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IT2018/000002 WO2019138433A1 (fr) 2018-01-12 2018-01-12 Procédé de fabrication d'un tube à essai destiné à être utilisé avec des pipettes d'aspiration ou de sédimentation et tube à essai ainsi obtenu

Publications (1)

Publication Number Publication Date
WO2019138433A1 true WO2019138433A1 (fr) 2019-07-18

Family

ID=61837793

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IT2018/000002 Ceased WO2019138433A1 (fr) 2018-01-12 2018-01-12 Procédé de fabrication d'un tube à essai destiné à être utilisé avec des pipettes d'aspiration ou de sédimentation et tube à essai ainsi obtenu

Country Status (1)

Country Link
WO (1) WO2019138433A1 (fr)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997012679A1 (fr) * 1995-10-03 1997-04-10 Beckman Instruments, Inc. Systeme et procede de separation du sang par rotation axiale
WO1998051412A1 (fr) * 1997-05-16 1998-11-19 Roberto Guglielmo Centrifugation a equilibre de densite et tube de test du sperme surnageant
US20150238969A1 (en) * 2014-02-21 2015-08-27 ORIGIO Inc. Pipette Tip Containers
US20170182489A1 (en) * 2014-04-09 2017-06-29 Greiner Bio-One Gmbh Receiver container and receiver unit for receiving body fluid
WO2017123504A1 (fr) * 2016-01-15 2017-07-20 Biotix, Inc. Composants et ensembles de capuchon et tube de manipulation de fluide

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997012679A1 (fr) * 1995-10-03 1997-04-10 Beckman Instruments, Inc. Systeme et procede de separation du sang par rotation axiale
WO1998051412A1 (fr) * 1997-05-16 1998-11-19 Roberto Guglielmo Centrifugation a equilibre de densite et tube de test du sperme surnageant
US20150238969A1 (en) * 2014-02-21 2015-08-27 ORIGIO Inc. Pipette Tip Containers
US20170182489A1 (en) * 2014-04-09 2017-06-29 Greiner Bio-One Gmbh Receiver container and receiver unit for receiving body fluid
WO2017123504A1 (fr) * 2016-01-15 2017-07-20 Biotix, Inc. Composants et ensembles de capuchon et tube de manipulation de fluide

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