WO2019140572A1 - Pansement pour plaie et son procédé de fabrication - Google Patents

Pansement pour plaie et son procédé de fabrication Download PDF

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Publication number
WO2019140572A1
WO2019140572A1 PCT/CN2018/073026 CN2018073026W WO2019140572A1 WO 2019140572 A1 WO2019140572 A1 WO 2019140572A1 CN 2018073026 W CN2018073026 W CN 2018073026W WO 2019140572 A1 WO2019140572 A1 WO 2019140572A1
Authority
WO
WIPO (PCT)
Prior art keywords
fiber
wound dressing
fibers
gel
thermoplastic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2018/073026
Other languages
English (en)
Chinese (zh)
Inventor
张俊丰
董杰
莫晋文
陈伟伟
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Huizhou Foryou Medical Devices Co Ltd
Original Assignee
Huizhou Foryou Medical Devices Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Huizhou Foryou Medical Devices Co Ltd filed Critical Huizhou Foryou Medical Devices Co Ltd
Priority to PCT/CN2018/073026 priority Critical patent/WO2019140572A1/fr
Publication of WO2019140572A1 publication Critical patent/WO2019140572A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/24—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/26—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28—Polysaccharides or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/60—Liquid-swellable gel-forming materials, e.g. super-absorbents

Definitions

  • the present invention relates to a dressing, in particular a wound dressing and a method of making the same.
  • wound dressings based on wet healing theory, such as alginate dressings, carboxymethyl cellulose dressings and chitosan dressings, are widely used in acute and chronic wound care.
  • the wound dressing contacts the wound exudate, it forms a soft gel that provides an ideal moist environment for wound healing.
  • the dressing when the dressing is used after being removed from the wound, the dressing cannot be completely removed due to the structural problem of the nonwoven fabric itself. The collapse or rupture of the dressing causes a portion of the dressing to remain in the wound, posing a risk that the wound must be flushed.
  • the present invention overcomes the deficiencies of the prior art by providing a wound dressing composition capable of gelling after contact with human wound exudate, and a wound dressing capable of maintaining the integrity of the dressing after removal after use. And a preparation method.
  • a wound dressing consisting of two or more kinds of fibers containing gel fiber, textile fiber and thermoplastic fiber, the gel fiber content is 50% to 100%, and the textile fiber content is 0%. 50%, the thermoplastic fiber content is 0% to 20%; the wound dressing has a gram weight of 60-200 g/cm2, a thickness of 0.5-5.0 mm, and a 0.9% saline solution having a liquid absorption of not less than 10 g/100 cm2.
  • the gel fiber is sodium carboxymethyl cellulose, chemically modified cellulose fiber, pectin fiber, alginate fiber, chitosan fiber, hyaluronic acid fiber, polysaccharide fiber. Or one of the gum fibers.
  • the cellulose fibers are having a degree of substitution of at least 0.05 carboxymethyl groups per glucose unit.
  • the gel fiber is an absorbent having at least 2 g of a 0.9% saline solution per gram of fiber.
  • the textile fiber is one of a tencel fiber, a viscose fiber, a nylon fiber, a polyester fiber, a nylon fiber, and a cotton fiber.
  • thermoplastic fiber is one or more of PE fiber, PP fiber, PET fiber, PS fiber, ABS fiber, PE/PET fiber, PE/PP fiber.
  • a method of preparing a wound dressing comprising the above wound dressing, the method for preparing a wound dressing comprising the steps of:
  • the mixed fiber provided has a gel fiber content of 50% to 100%, a textile fiber content of 0% to 50%, a thermoplastic fiber content of 0% to 20%, and the gel fiber, textile fiber and thermoplastic Fiber blending;
  • the wound dressing after the needle punching is hot-rolled and set, and the temperature during hot rolling is not less than 110 °C.
  • the wound dressing is a composition, which is simple in preparation method, and the wound dressing composition can gel after contacting the human wound exudate, and can maintain the integrity of the dressing after being removed after use. Sex.
  • a wound dressing provided by an embodiment of the present invention comprises two or more kinds of fibers including gel fiber, textile fiber and thermoplastic fiber, wherein the gel fiber content is 50% to 100%, and the textile fiber content is 0%. ⁇ 50%, the thermoplastic fiber content is 0% to 20%; the wound dressing has a gram weight of 60-200 g/cm2, a thickness of 0.5-5.0 mm, and a 0.9% saline solution having a liquid absorption of not less than 10 g/100 cm2.
  • the gel fiber is sodium carboxymethyl cellulose, chemically modified cellulose fiber, pectin fiber, alginate fiber, chitosan fiber, hyaluronic acid fiber, polysaccharide fiber or gum.
  • pectin fiber sodium carboxymethyl cellulose
  • alginate fiber sodium carboxymethyl cellulose
  • chitosan fiber alginate fiber
  • hyaluronic acid fiber polysaccharide fiber or gum.
  • the cellulosic fibers are having a degree of substitution of at least 0.05 carboxymethyl groups per glucose unit.
  • the gel fiber is absorbent having at least 2 grams of 0.9% saline solution per gram of fiber.
  • the textile fiber is one of a tencel fiber, a viscose fiber, a nylon fiber, a polyester fiber, a nylon fiber, and a cotton fiber.
  • thermoplastic fiber is one or more of PE fiber, PP fiber, PET fiber, PS fiber, ABS fiber, PE/PET fiber, PE/PP fiber.
  • a method of preparing a wound dressing comprising the above wound dressing, the method for preparing a wound dressing comprising the steps of:
  • the mixed fiber provided has a gel fiber content of 50% to 100%, a textile fiber content of 0% to 50%, a thermoplastic fiber content of 0% to 20%, and the gel fiber, textile fiber and thermoplastic Fiber blending;
  • the wound dressing after the needle punching is hot-rolled and set, and the temperature during hot rolling is not less than 110 °C.
  • the wound dressing is a composition which is simple to prepare and which is capable of gelling upon contact with human wound exudate and which maintains the integrity of the dressing upon removal after use.
  • the present invention forms a wound dressing having a three-dimensional network structure by blending, acupuncture and hot rolling a gel fiber, a textile fiber and a thermoplastic fiber.
  • the three components of the dressing have their own functions, the gel fiber has high liquid absorption property, can form a soft gel, and provides an ideal moist environment for wound healing; the textile fiber can increase the wet strength of the dressing, improve the wicking effect; thermoplastic After the fiber is hot rolled, a three-dimensional network structure is formed, which increases the wet strength and reduces the fiber drop.
  • the wound dressing prepared by the method has the advantages of high liquid absorption, less fiber drop, less gel shrinkage, high wet strength, good compliance, and can be removed as a whole.
  • the technical effects brought by the invention have the advantages of high liquid absorption, less fiber drop, small shrinkage ratio, enhanced wet strength and good compliance.

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Materials For Medical Uses (AREA)

Abstract

La présente invention concerne un pansement pour plaie et son procédé de fabrication. Le pansement pour plaie comprend deux ou plusieurs parmi une fibre de gel, une fibre textile, et une fibre thermoplastique. La teneur en fibre de gel est de 50 à 100 %. La teneur en fibre textile est de 0 à 50 %. La teneur en fibre thermoplastique est de 0 à 20 %. Le poids en grammes du pansement pour plaie est de 60 à 200 g/cm2. L'épaisseur est de 0,5 à 5,0 mm. L'absorption de liquide est d'au moins 10 g/100 cm2 d'une solution saline à 0,9 %. Le procédé de fabrication comprend : la préparation d'un mélange de la fibre de gel, de la fibre textile, et de la fibre thermoplastique et leur mélange ; l'aiguilletage du pansement pour plaie mélangé ; et le thermodurcissage du pansement pour plaie aiguilleté par roulage à chaud. La composition de pansement pour plaie peut subir la gélification après mise en contact de l'exsudat de la plaie et est susceptible de maintenir l'intégrité du pansement lorsqu'elle est décollée après utilisation.
PCT/CN2018/073026 2018-01-17 2018-01-17 Pansement pour plaie et son procédé de fabrication Ceased WO2019140572A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/CN2018/073026 WO2019140572A1 (fr) 2018-01-17 2018-01-17 Pansement pour plaie et son procédé de fabrication

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2018/073026 WO2019140572A1 (fr) 2018-01-17 2018-01-17 Pansement pour plaie et son procédé de fabrication

Publications (1)

Publication Number Publication Date
WO2019140572A1 true WO2019140572A1 (fr) 2019-07-25

Family

ID=67301910

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2018/073026 Ceased WO2019140572A1 (fr) 2018-01-17 2018-01-17 Pansement pour plaie et son procédé de fabrication

Country Status (1)

Country Link
WO (1) WO2019140572A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102022003230A1 (de) 2022-09-02 2024-03-07 Giesecke+Devrient Currency Technology Gmbh Sicherheitselement mit farberzeugenden Nanostrukturen und Herstellverfahren dafür

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0740554B1 (fr) * 1994-01-20 2003-04-02 Bristol-Myers Squibb Company Pansement
US20030104204A1 (en) * 2001-05-10 2003-06-05 The Procter & Gamble Company Multicomponent fibers comprising starch and polymers
CN101348973A (zh) * 2007-07-20 2009-01-21 远东纺织股份有限公司 热可塑纤维/机能性纤维混纺织物及含该混纺织物的敷料
DE102007049430A1 (de) * 2007-10-14 2009-04-16 Birgit Riesinger Wundpflegeartikel, aufweisend mindestens einen Anteil an stützenden Fasern und einen Anteil an hydroaktiven Polymeren
CN103463670A (zh) * 2013-09-18 2013-12-25 佛山市优特医疗科技有限公司 一种含有低熔点纤维的伤口敷料及其制造方法
CN104024498A (zh) * 2011-11-01 2014-09-03 布莱特维克公司 伤口敷料以及可用于伤口敷料中的线
CN105233327A (zh) * 2015-11-09 2016-01-13 佛山市优特医疗科技有限公司 一种季铵化壳聚糖纤维及吸湿抗菌伤口敷料
CN105521519A (zh) * 2015-12-18 2016-04-27 厦门百美特生物材料科技有限公司 一种藻酸盐敷芯
CN106267303A (zh) * 2015-05-12 2017-01-04 3M创新有限公司 吸湿件、吸湿袋、及其制备方法和应用
CN108498840A (zh) * 2018-01-17 2018-09-07 惠州华阳医疗器械有限公司 一种伤口敷料及其制备方法

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0740554B1 (fr) * 1994-01-20 2003-04-02 Bristol-Myers Squibb Company Pansement
US20030104204A1 (en) * 2001-05-10 2003-06-05 The Procter & Gamble Company Multicomponent fibers comprising starch and polymers
CN101348973A (zh) * 2007-07-20 2009-01-21 远东纺织股份有限公司 热可塑纤维/机能性纤维混纺织物及含该混纺织物的敷料
DE102007049430A1 (de) * 2007-10-14 2009-04-16 Birgit Riesinger Wundpflegeartikel, aufweisend mindestens einen Anteil an stützenden Fasern und einen Anteil an hydroaktiven Polymeren
CN104024498A (zh) * 2011-11-01 2014-09-03 布莱特维克公司 伤口敷料以及可用于伤口敷料中的线
CN103463670A (zh) * 2013-09-18 2013-12-25 佛山市优特医疗科技有限公司 一种含有低熔点纤维的伤口敷料及其制造方法
CN106267303A (zh) * 2015-05-12 2017-01-04 3M创新有限公司 吸湿件、吸湿袋、及其制备方法和应用
CN105233327A (zh) * 2015-11-09 2016-01-13 佛山市优特医疗科技有限公司 一种季铵化壳聚糖纤维及吸湿抗菌伤口敷料
CN105521519A (zh) * 2015-12-18 2016-04-27 厦门百美特生物材料科技有限公司 一种藻酸盐敷芯
CN108498840A (zh) * 2018-01-17 2018-09-07 惠州华阳医疗器械有限公司 一种伤口敷料及其制备方法

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102022003230A1 (de) 2022-09-02 2024-03-07 Giesecke+Devrient Currency Technology Gmbh Sicherheitselement mit farberzeugenden Nanostrukturen und Herstellverfahren dafür
WO2024047258A1 (fr) 2022-09-02 2024-03-07 Giesecke+Devrient Currency Technology Gmbh Élément de sécurité doté de nanostructures de production de couleur et son procédé de production

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