WO2020002133A1 - Procédés et appareil d'administration de mesures à l'aide d'un timbre à électrodes multiples et à dérivation unique - Google Patents

Procédés et appareil d'administration de mesures à l'aide d'un timbre à électrodes multiples et à dérivation unique Download PDF

Info

Publication number
WO2020002133A1
WO2020002133A1 PCT/EP2019/066424 EP2019066424W WO2020002133A1 WO 2020002133 A1 WO2020002133 A1 WO 2020002133A1 EP 2019066424 W EP2019066424 W EP 2019066424W WO 2020002133 A1 WO2020002133 A1 WO 2020002133A1
Authority
WO
WIPO (PCT)
Prior art keywords
electrodes
patient
vector
differential signal
define
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2019/066424
Other languages
English (en)
Inventor
Joseph Alexander COVIELLO
Paul BRANCHE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koninklijke Philips NV
Original Assignee
Koninklijke Philips NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Philips NV filed Critical Koninklijke Philips NV
Publication of WO2020002133A1 publication Critical patent/WO2020002133A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0004—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by the type of physiological signal transmitted
    • A61B5/0006—ECG or EEG signals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/024—Measuring pulse rate or heart rate
    • A61B5/02438—Measuring pulse rate or heart rate with portable devices, e.g. worn by the patient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/024—Measuring pulse rate or heart rate
    • A61B5/0245—Measuring pulse rate or heart rate by using sensing means generating electric signals, i.e. ECG signals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/30—Input circuits therefor
    • A61B5/304—Switching circuits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/30—Input circuits therefor
    • A61B5/307—Input circuits therefor specially adapted for particular uses
    • A61B5/308—Input circuits therefor specially adapted for particular uses for electrocardiography [ECG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7221—Determining signal validity, reliability or quality
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/04—Arrangements of multiple sensors of the same type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6802—Sensor mounted on worn items
    • A61B5/681—Wristwatch-type devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6887—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient mounted on external non-worn devices, e.g. non-medical devices
    • A61B5/6898—Portable consumer electronic devices, e.g. music players, telephones, tablet computers

Definitions

  • Various embodiments described herein are directed generally to health care. More particularly, but not exclusively, various methods and apparatus disclosed herein relate to selecting electrodes that are then utilized to perform physiological measurements, such as electrocardiogram (“ECG”) measurements.
  • ECG electrocardiogram
  • Single-lead ECG measurement devices are highly dependent on lead vector orientation between a pair of electrodes to obtain a clean (low noise), discemable signal for measurement and analysis. This is largely affected by variations in the patient’s own anatomy such as the alignment of the heart in the chest, fat distribution and/or skin impedance. Conventional disposable single-lead ECG patches can be wasted by trying to locate the proper electrode orientation given patient-to-patient variability.
  • ECG measurement devices utilize multiple vectors across the heart and often default to the strongest signal when calculating heart rate and performing arrhythmia analyses. This is beneficial if an electrode dries (high impedance leading to a noisy or lost signal) or falls off, which may interrupt monitoring.
  • Devices, apparatus, and techniques are described herein relating to application of a patch with a plurality of electrodes that define multiple selectable vectors, such as ECG vectors, to choose from.
  • Being able to select from multiple different vectors greatly mitigates issues raised by anatomical differences from person-to-person, such as the need to search for proper placement, location, or orientation.
  • the patch can be applied by the patient or by an untrained family member without the requirement of a clinician applying the patch.
  • the redundancy of the multiple selectable vectors allows for flexibility when implementing accurate monitoring of various medical parameters, such as ECG. For example, if one of the electrodes of the patch dries out or lifts off the skin due to poor adhesion, it is still possible to perform ECG monitoring.
  • Various embodiments in this disclosure address this problem by facilitating selection from multiple different pairs of electrodes, with each electrode pair defining a selectable vector.
  • Apparatus described herein are further able to utilize lead redundancy by toggling from lead to lead to search for the strongest signal between electrodes and/or a most suitable vector for analysis using lead selection control logic. This is not an option for existing single lead ECGs. The more electrodes on the patch, the more redundancy possible due to the increased availability of selectable vectors between pairs of electrodes.
  • Apparatus and devices described herein are lower cost than conventional multiple lead ECG devices, while allowing for the flexibility of conventional multiple lead ECG devices. Additionally, cost and size savings in circuitry are achieved by only measuring one signal at a time, which is a beneficial characteristic for a disposable wearable.
  • a signal between each electrode pair of the plurality of electrodes on the patch may be measured through the use of a controlled switch, which enables any electrode pair to be selected for use in obtaining a physiological measurement.
  • a non-invasive electrocardiogram, (“ECG”) apparatus may include: a substrate affix-able to skin of a patient; at least three electrodes positioned on one side of the substrate to contact the skin of the patient, wherein the at least three electrodes define a plurality of vectors between them, each vector of the plurality of vectors defined by a respective candidate pair of the at least three electrodes; a logic device that performs a lead vector selection process based on one or more signal strengths between one or more candidate pairs of the at least three electrodes to select a suitable vector from the plurality of vectors for use with an ECG test; a controlled switch to receive a command from the logic device to select the candidate pair of electrodes that define the suitable vector and output a corresponding differential signal from the candidate pair of electrodes that define the suitable vector; and single lead ECG circuitry to receive as input the differential signal from the controlled switch and provide output to the logic device based on the received input.
  • the apparatus may further include a communication interface.
  • the logic device may be further configured to: determine a heart rate based on the provided output; and provide, via the communication interface, information indicative of the determined heart rate to a remote computing device.
  • the information may cause the remote computing device to display the heart rate.
  • the logic device may be further configured to provide information indicative of the provided output to a remote computing device, wherein the information indicative of the provided output causes the remote computing to display a heart rate of the patient.
  • the logic device may be further configured to perform analysis on the output provided by the single lead ECG circuitry to detect an arrhythmia.
  • the controlled switch may take the form of a multiplexer.
  • the received input may take the form of a voltage measured at a first of the pair of electrodes that together define the selected suitable vector and a voltage measured at a second of the pair of electrodes that together define the selected suitable vector.
  • a method of measuring electrical activity of the heart of a patient may include: affixing a substrate to skin of the patient, wherein the substrate includes at least three electrodes positioned on one side of the substrate to contact the skin of the patient, wherein the at least three electrodes define a plurality of vectors between them, each vector of the plurality of vectors defined by a respective candidate pair of the at least three electrodes;
  • FIG. 1 schematically illustrates one example of how apparatus configured with selected aspects of the present disclosure may be deployed on a patient, in accordance with various embodiments.
  • FIG. 2 schematically illustrates one example of components that may be employed in one of the embodiments of the present disclosure.
  • FIG. 3 illustrates an example method for performing selected aspects of the present disclosure, in accordance with various embodiments.
  • FIG. 4 illustrates another example method for performing selected aspects of the present disclosure, in accordance with various embodiments.
  • Electrodes of this disclosure facilitate lead selection from a plurality of electrodes on a patch or other similar substrate.
  • the electrodes may be isolated from each other electrically.
  • Each pair of electrodes also referred to herein as a“candidate pair” may form a vector through the patient’s body by which voltage is measured between the first electrode and the second electrode in the candidate pair.
  • electricity e.g., current, voltage
  • a bioimpedance signal may be measured through the use of current being applied to the patient through the isolated electrodes.
  • ECG ECG
  • bioimpedance signal a physiological measurement
  • This device can be applied in many scenarios where an ECG is used (hospital, ambulatory, home) by anyone (patient, family member, clinician) for wearable applications with improved confidence that a usable signal can be obtained without having to reapply the patch for the duration of use.
  • This design while geared for low-cost disposable applications, could be extended to reusable ECGs by allowing the electrodes to be removable.
  • animals dogs, cats, horses
  • any physiological signal requiring electrodes such an impedance based measurements also benefit from this disclosure.
  • a user 101 is depicted wearing an apparatus 200 configured with selected aspects of the present disclosure.
  • user 101 may wear apparatus 200 at various locations on her body, preferably on the user’s chest, but it can also be applied to her back, neck, etc.
  • apparatus 200 may be configured to communicate with one or more remote computing devices, e.g., using wired and/or wireless communication interface 211 that employs technologies such as Wi-Fi, Bluetooth, Ethernet, etc.
  • apparatus 200 is in wireless communication with a computing device taking the form of a smart phone 218 carried by user 101.
  • smart phone 218 receives, via the wireless communication channel, electrocardiogram (“ECG”) measurements from apparatus 200 and displays information indicative of those measurements on its display.
  • ECG electrocardiogram
  • FIG. 2 schematically depicts in more detail than Fig. 1 one example of components that may be included with apparatus 200, in accordance with various embodiments.
  • apparatus 200 includes a multi-electrode patient interface 204 on which a plurality of electrodes 202 I-4 are positioned, a controlled switch 206 (e.g., a multiplexor or“MUX”), single lead ECG circuitry 212 and a logic device 216. While four electrodes 202i- 4 are depicted in Fig. 2, this is not meant to be limiting. The number of electrodes is scalable to any number above two.
  • Each pair of electrodes ⁇ 202x, 202 g> defines a selectable vector 203X-Y between them. For example, one vector defined between first electrode 202i and third electrode 202 3 is designated as 2031-3. Another vector defined between third electrode 202 3 and second electrode 202 2 is designated as 203 2-3 . And so forth.
  • the logic device 216 may take various forms, such as one or more processors, a field- programmable gate array (“FPGA”), an application-specific integrated circuit (“ASIC”), and so forth.
  • logic device 216 may be configured to select one or more vectors 203 from the plurality of vectors using a lead selection control signal 220 to controlled switch 206, as part of what will be referred to herein as a“lead vector selection process.”
  • the selected vector 203 may include the pair of electrodes 202 that define endpoints to the selected vector 203.
  • the logic device 216 may send lead selection logic
  • sequence of differential signals 208/210 may cause single lead ECG circuitry 212 to output a corresponding sequence of ECG signals 214 that are received as input by logic device 216 as part of a feedback loop.
  • logic device 216 may identify a suitable ECG signal 214 associated with a particular vector 203 between particular pair of electrodes 202.
  • An ECG signal may be determined to be suitable in various ways. For example, in some embodiments, the strongest ECG signal 214 of the sequence of ECG signals received by logic device 216 may be selected.
  • the first ECG signal 214 of the sequence of ECG signals received by logic device 216 that satisfies some criterion may be selected, so that not necessarily every candidate pair of electrodes 202 need be tested.
  • single-lead ECG circuitry 212 may be configured to condition the differential raw signals 208/210, and hence may include one or more amplifiers and/or filters. In some embodiments, single-lead ECG circuitry 212 may be configured to protect a patient from leakage current and provide further protection to the device from electrostatic discharge (ESD) and defibrillation.
  • ESD electrostatic discharge
  • single-lead ECG circuitry 212 may additionally or alternatively include an analog-to-digital convertor, such that output of the single-lead ECG circuitry 212 takes the form of a single-ended ECG signal 214.
  • the ECG signal 214 may be sent from the single-lead ECG circuitry 212 to the logic device 216.
  • data indicative of the ECG signal 214 such as the raw signal, may be transmitted by the logic device 216 using wireless and/or wired
  • remote computing devices 218, such as a mobile phone, smart watch, medical device, etc.
  • These remote devices may be configured to provide audio and/or visual output indicative of the ECG signal or various information derived therefrom, such as a heart rate, one or more detected arrhythmias, etc.
  • patient/multi-electrode interface 204 represents the point at which the device 200 electrically couples to the patient’s skin.
  • patient/multi-electrode interface 204 may take the form of a substrate such as a patch with adhesive on one surface (e.g., on the same surface that hosts the electrodes 202) that is usable to affix patient/multi-electrode interface 204 to the patient’s skin.
  • a substrate such as a patch with adhesive on one surface (e.g., on the same surface that hosts the electrodes 202) that is usable to affix patient/multi-electrode interface 204 to the patient’s skin.
  • this is not meant to be limiting.
  • Patient/multi electrode interface 204 may take other forms in other embodiments, such as non-adhesive generally-planar devices (e.g., plates), a surface of a mobile computing device (e.g., a smart phone or smart watch) that includes a plurality of electrodes, etc.
  • Other components in Fig. 2 may or may not also be positioned on patient/multi-electrode interface 204.
  • measurements obtained from the electrodes 202 at each endpoint of the selected vector 203 are used.
  • the first selected electrode’s measurement 208 and the second selected electrode’s measurement 210 are transmitted by the controlled switch 206 to single lead ECG circuitry 212, as described previously.
  • the controlled switch 206 may take the form of a digitally controlled analog switch that allows for any electrode to pair with any other electrode to form the differential signal fed into the single-lead ECG circuit.
  • a dual 4:1 multiplexer (“mux”) is used as the controlled switch 206.
  • this is not meant to be limiting.
  • an embodiment with eight electrodes may use a dual 8: 1 mux.
  • Fig. 3 depicts an example method 300 for practicing selected aspects of the present disclosure, in accordance with various embodiments. While operations of method 300 are shown in a particular order, this is not meant to be limiting. One or more operations may be reordered, omitted or added.
  • a substrate such as a patch (e.g., 204) may be affixed to skin of a patient (e.g., 101) at various locations, such as on the patient’s chest, back, arm(s), leg(s), neck, etc.
  • the substrate is affixed by way of a biocompatible adhesive that is applied to one side of the substrate.
  • the substrate may include three or more electrodes, with each candidate pair of electrodes forming a vector by which voltage is measured between the first electrode and the second electrode in the candidate pair of electrodes using the internal body tissue of the patient as the method in which the voltage travels from the first electrode to the second electrode.
  • a bioimpedance signal may be measured through the use of current being applied to the patient through the isolated electrodes.
  • one or more components may perform a lead vector selection process.
  • a lead selection process is depicted in Fig. 4.
  • a suitable vector defined by a pair of the three or more electrodes is selected.
  • the controlled switch 206 may be operated to select (e.g., obtain voltage measurements from) the pair of electrodes that defines the suitable vector selected at block 306, such that controlled switch 206 outputs, e.g., to single-lead ECG circuitry 212, a differential signal.
  • logic device 216 may send a lead selection control logic command 220 to controlled switch 206 that causes controlled switch 206 to provide, as output to single-lead ECG circuitry 212, a differential signal (208/210) between the electrode pair defining the suitable vector selected at block 306.
  • electrical activity of the patient’s heart may be determined, e.g., by logic device 216 and/or by a remote computing device (e.g., 218) to which logic device 216 transmits data.
  • logic device 216 itself may determine a heart rate, detect an arrhythmia, etc., or may transmit raw data to a remote computing device that may determine heart rate, detect an arrhythmia, etc.
  • information indicative of the electrical activity of the patient’s heart may be output, e.g., as an ECG signal waveform, numerically, etc., in visual, audible, or even haptic form.
  • Fig. 4 depicts an example method 400/302 for performing a lead vector selection process (i.e., block 304 of Fig. 3. While operations of method 400/302 are shown in a particular order, this is not meant to be limiting. One or more operations may be reordered, omitted or added.
  • a determination may be made, e.g., by logic device 216, of whether there are any untested candidate pairs of electrodes (202).
  • a next candidate pair of electrodes may be set as the current candidate pair.
  • logic device 216 may instruct controlled switch 206 to allow signals from the current candidate pair of electrodes to pass through, and to block signals from other electrodes.
  • voltage may be measured across a vector defined by the current candidate pair of electrodes.
  • current may be applied to the patient through the electrodes.
  • it may be determined, e.g., by logic device 216 based on a signal received from single-lead ECG circuitry 212, whether one or more criteria are satisfied.
  • the criteria may include a minimum signal strength being satisfied, in which case any signal that satisfies the threshold may be sufficient to obtain a physiological measurement.
  • the criterion may be correlated to the Signal Quality Index (SQI), which is a measurement of ECG signal quality based on a signal-to-noise ratio.
  • SQL Signal Quality Index
  • method 400 may proceed back to block 402, and the loop defined by blocks 402-408 may repeat. However, if the answer at block 408 is yes, then at block 410 (which may correspond to block 306 of Fig. 3), the vector defined by the current pair of electrodes may be selected, e.g., by logic device 216, as the suitable vector. Method 400 may then pass control back to block 308 ofFig. 3.
  • suitable vectors may be selected differently. For example, in some embodiments, all possible vectors between all possible pairs of electrodes may be tested, and the vector having the strongest signal strength may be selected. Additionally or
  • a predetermined vector defined by a particular pair of electrodes may be selected based on the intended application. For example, if electrical activity through a particular vector of the patient’s body needs to be measured, then electrodes that define a corresponding vector may be selected.
  • inventive embodiments are presented by way of example only and that, within the scope of the appended claims and equivalents thereto, inventive embodiments may be practiced otherwise than as specifically described and claimed.
  • inventive embodiments of the present disclosure are directed to each individual feature, system, article, material, kit, and/or method described herein.
  • a reference to“A and/or B”, when used in conjunction with open-ended language such as“comprising” can refer, in one embodiment, to A only (optionally including elements other than B); in another embodiment, to B only (optionally including elements other than A); in yet another embodiment, to both A and B (optionally including other elements); etc.
  • “or” should be understood to have the same meaning as“and/or” as defined above.
  • “or” or“and/or” shall be interpreted as being inclusive, i.e., the inclusion of at least one, but also including more than one, of a number or list of elements, and, optionally, additional unlisted items. Only terms clearly indicated to the contrary, such as“only one of’ or“exactly one of,” or, when used in the claims,“consisting of,” will refer to the inclusion of exactly one element of a number or list of elements.
  • the phrase“at least one,” in reference to a list of one or more elements, should be understood to mean at least one element selected from any one or more of the elements in the list of elements, but not necessarily including at least one of each and every element specifically listed within the list of elements and not excluding any combinations of elements in the list of elements.
  • This definition also allows that elements may optionally be present other than the elements specifically identified within the list of elements to which the phrase“at least one” refers, whether related or unrelated to those elements specifically identified.
  • “at least one of A and B” can refer, in one embodiment, to at least one, optionally including more than one, A, with no B present (and optionally including elements other than B); in another embodiment, to at least one, optionally including more than one, B, with no A present (and optionally including elements other than A); in yet another embodiment, to at least one, optionally including more than one, A, and at least one, optionally including more than one, B (and optionally including other elements); etc.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Physiology (AREA)
  • Signal Processing (AREA)
  • Artificial Intelligence (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Psychiatry (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)

Abstract

L'invention concerne un appareil, des systèmes et des techniques permettant de mesurer l'activité électrique d'un patient. Dans divers modes de réalisation, un appareil d'électrocardiogramme (« ECG ») non invasif peut comprendre : un substrat (204) pouvant être fixé à la peau d'un patient ; au moins trois électrodes (202) positionnées sur le substrat pour entrer en contact avec la peau du patient, les électrodes définissant une pluralité de vecteurs (203) entre eux, chaque vecteur étant défini par une paire candidate respective des électrodes ; un dispositif logique (216) qui sélectionne un vecteur approprié pour une utilisation avec un test d'ECG ; un commutateur commandé (206) pour recevoir une commande provenant du dispositif logique pour sélectionner la paire candidate d'électrodes qui définissent le vecteur approprié et délivrer en sortie un signal différentiel correspondant (208/210) ; et un circuit d'ECG à dérivation unique (212) pour recevoir le signal différentiel provenant du commutateur commandé et fournir une sortie au dispositif logique sur la base d'un signal différentiel.
PCT/EP2019/066424 2018-06-27 2019-06-21 Procédés et appareil d'administration de mesures à l'aide d'un timbre à électrodes multiples et à dérivation unique Ceased WO2020002133A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862690457P 2018-06-27 2018-06-27
US62/690,457 2018-06-27

Publications (1)

Publication Number Publication Date
WO2020002133A1 true WO2020002133A1 (fr) 2020-01-02

Family

ID=67060393

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2019/066424 Ceased WO2020002133A1 (fr) 2018-06-27 2019-06-21 Procédés et appareil d'administration de mesures à l'aide d'un timbre à électrodes multiples et à dérivation unique

Country Status (1)

Country Link
WO (1) WO2020002133A1 (fr)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD917704S1 (en) 2019-08-16 2021-04-27 Masimo Corporation Patient monitor
USD919100S1 (en) 2019-08-16 2021-05-11 Masimo Corporation Holder for a patient monitor
USD919094S1 (en) 2019-08-16 2021-05-11 Masimo Corporation Blood pressure device
USD921202S1 (en) 2019-08-16 2021-06-01 Masimo Corporation Holder for a blood pressure device
USD927699S1 (en) 2019-10-18 2021-08-10 Masimo Corporation Electrode pad
USD933232S1 (en) 2020-05-11 2021-10-12 Masimo Corporation Blood pressure monitor
US20210369172A1 (en) * 2020-05-29 2021-12-02 Vuno Inc. Portable ecg measuring device
US11576582B2 (en) 2015-08-31 2023-02-14 Masimo Corporation Patient-worn wireless physiological sensor
USD979516S1 (en) 2020-05-11 2023-02-28 Masimo Corporation Connector
WO2023046323A1 (fr) * 2021-09-22 2023-03-30 National University Of Ireland, Galway Dispositif et système pour détecter des anomalies du rythme cardiaque
US11637437B2 (en) 2019-04-17 2023-04-25 Masimo Corporation Charging station for physiological monitoring device
USD985498S1 (en) 2019-08-16 2023-05-09 Masimo Corporation Connector

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110125002A1 (en) * 2009-10-27 2011-05-26 Ershov Sergey Signal detecting device for detecting a difference signal for an electrical measurement of a vital parameter of a living being, electrode arrangement and method
US20110288605A1 (en) * 2010-05-18 2011-11-24 Zoll Medical Corporation Wearable ambulatory medical device with multiple sensing electrodes
US20170113053A1 (en) * 2015-10-23 2017-04-27 Cardiac Pacemakers, Inc. Signal quality monitoring for multiple sense vectors in cardiac devices

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110125002A1 (en) * 2009-10-27 2011-05-26 Ershov Sergey Signal detecting device for detecting a difference signal for an electrical measurement of a vital parameter of a living being, electrode arrangement and method
US20110288605A1 (en) * 2010-05-18 2011-11-24 Zoll Medical Corporation Wearable ambulatory medical device with multiple sensing electrodes
US20170113053A1 (en) * 2015-10-23 2017-04-27 Cardiac Pacemakers, Inc. Signal quality monitoring for multiple sense vectors in cardiac devices

Cited By (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11576582B2 (en) 2015-08-31 2023-02-14 Masimo Corporation Patient-worn wireless physiological sensor
US12150739B2 (en) 2015-08-31 2024-11-26 Masimo Corporation Systems and methods for patient fall detection
US12133717B2 (en) 2015-08-31 2024-11-05 Masimo Corporation Systems and methods for patient fall detection
US12533068B2 (en) 2019-04-17 2026-01-27 Masimo Corporation Physiological monitoring device attachment assembly
US12433524B2 (en) 2019-04-17 2025-10-07 Masimo Corporation Electrocardiogram device
US12390140B2 (en) 2019-04-17 2025-08-19 Masimo Corporation Blood pressure cuff
US12178581B2 (en) 2019-04-17 2024-12-31 Masimo Corporation Patient monitoring systems, devices, and methods
US11986305B2 (en) 2019-04-17 2024-05-21 Masimo Corporation Liquid inhibiting air intake for blood pressure monitor
US11701043B2 (en) 2019-04-17 2023-07-18 Masimo Corporation Blood pressure monitor attachment assembly
US11678829B2 (en) 2019-04-17 2023-06-20 Masimo Corporation Physiological monitoring device attachment assembly
US11637437B2 (en) 2019-04-17 2023-04-25 Masimo Corporation Charging station for physiological monitoring device
USD1037462S1 (en) 2019-08-16 2024-07-30 Masimo Corporation Holder for a patient monitor
USD933234S1 (en) 2019-08-16 2021-10-12 Masimo Corporation Patient monitor
USD919100S1 (en) 2019-08-16 2021-05-11 Masimo Corporation Holder for a patient monitor
USD919094S1 (en) 2019-08-16 2021-05-11 Masimo Corporation Blood pressure device
USD921202S1 (en) 2019-08-16 2021-06-01 Masimo Corporation Holder for a blood pressure device
USD985498S1 (en) 2019-08-16 2023-05-09 Masimo Corporation Connector
USD1066672S1 (en) 2019-08-16 2025-03-11 Masimo Corporation Patient monitor and holder
USD933233S1 (en) 2019-08-16 2021-10-12 Masimo Corporation Blood pressure device
USD917704S1 (en) 2019-08-16 2021-04-27 Masimo Corporation Patient monitor
USD967433S1 (en) 2019-08-16 2022-10-18 Masimo Corporation Patient monitor
USD927699S1 (en) 2019-10-18 2021-08-10 Masimo Corporation Electrode pad
USD950738S1 (en) 2019-10-18 2022-05-03 Masimo Corporation Electrode pad
USD933232S1 (en) 2020-05-11 2021-10-12 Masimo Corporation Blood pressure monitor
USD1060680S1 (en) 2020-05-11 2025-02-04 Masimo Corporation Blood pressure monitor
USD965789S1 (en) 2020-05-11 2022-10-04 Masimo Corporation Blood pressure monitor
USD979516S1 (en) 2020-05-11 2023-02-28 Masimo Corporation Connector
US11980471B2 (en) * 2020-05-29 2024-05-14 Vuno Inc. Portable ECG measuring device
US20210369172A1 (en) * 2020-05-29 2021-12-02 Vuno Inc. Portable ecg measuring device
WO2023046323A1 (fr) * 2021-09-22 2023-03-30 National University Of Ireland, Galway Dispositif et système pour détecter des anomalies du rythme cardiaque

Similar Documents

Publication Publication Date Title
US12414724B2 (en) Electrocardiogram measurement apparatus
US9291654B2 (en) Patient electrode impedance measurement
US10939840B2 (en) Contactless electric cardiogram system
US10219719B2 (en) Head-mounted electrode array
EP3229665B1 (fr) Technologies de surveillance de contact d'électrode par rétroaction biologique
US20220054820A1 (en) Wearable devices
US20150374244A1 (en) Apparatus for continuously and automatically measuring pulse wave and method for measuring blood pressure
CN103239221B (zh) 测量生物电势的电极及其制造方法和测量生理信号的系统
JP3104991B2 (ja) 電極アッセンブリ
US11963777B2 (en) Quantification and of electrocardiogramag drive function system and method
CN108714027B (zh) 一种用于实时测量多路电极/头皮接触阻抗的装置及测量方法
EP3209197B1 (fr) Procédé et appareil d'essai d'impédance simultané
US12629076B2 (en) Screen printed electrodes for an electrocardiogram article
CN103860164A (zh) 一种心电驱动导联自动切换的方法和装置
WO2014051590A1 (fr) Système et procédé de détection du statut des électrodes d'un dispositif de surveillance d'un patient
Foster et al. 3D-printed electrocardiogram electrodes for heart rate detection in canines
KR101843083B1 (ko) 다중의 단위 측정기들을 포함하는 생체 신호 측정 장치 및 방법
KR101885320B1 (ko) 사용이 용이한 일회용 심전도 패드
KR101375443B1 (ko) 리드가 없는 무선 심전도 측정 시스템과 심장의 생체 활동 전위 측정 방법
Gaxiola-Sosa et al. A portable 12-lead ECG wireless medical system for continuous cardiac-activity monitoring
KR20160124400A (ko) 장갑형 생체신호 계측장치
KR20210013742A (ko) 심전도 측정 장치
US12233276B2 (en) Automatic lead switching
JP2026513501A (ja) 身体センサの最適な配置を検証するための方法及びシステム
HK40102772A (en) Electrocardiogram measurement apparatus

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 19733450

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 19733450

Country of ref document: EP

Kind code of ref document: A1