WO2020132494A3 - Procédés de pronostic, de diagnostic et de traitement du cancer gastrique - Google Patents

Procédés de pronostic, de diagnostic et de traitement du cancer gastrique Download PDF

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Publication number
WO2020132494A3
WO2020132494A3 PCT/US2019/067942 US2019067942W WO2020132494A3 WO 2020132494 A3 WO2020132494 A3 WO 2020132494A3 US 2019067942 W US2019067942 W US 2019067942W WO 2020132494 A3 WO2020132494 A3 WO 2020132494A3
Authority
WO
WIPO (PCT)
Prior art keywords
gastric cancer
prognosing
diagnosing
mir
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2019/067942
Other languages
English (en)
Other versions
WO2020132494A2 (fr
Inventor
Ajay Goel
Tadanobu SHIMURA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baylor Research Institute
Original Assignee
Baylor Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baylor Research Institute filed Critical Baylor Research Institute
Publication of WO2020132494A2 publication Critical patent/WO2020132494A2/fr
Publication of WO2020132494A3 publication Critical patent/WO2020132494A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La présente invention concerne une signature de miARN pour la détection du cancer gastrique. Des aspects de l'invention concernent un procédé de traitement, d'évaluation, de pronostic et/ou de diagnostic d'un patient pour traiter un patient atteint d'un cancer gastrique, le procédé comprenant le traitement du patient atteint d'un cancer gastrique après que le niveau d'expression de miR-30a-5p, miR-134-5p, miR-337-3p, miR-659-3p, et miR-3917 a été déterminé dans un échantillon provenant du patient.
PCT/US2019/067942 2018-12-21 2019-12-20 Procédés de pronostic, de diagnostic et de traitement du cancer gastrique Ceased WO2020132494A2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201862784240P 2018-12-21 2018-12-21
US62/784,240 2018-12-21
US201962811080P 2019-02-27 2019-02-27
US62/811,080 2019-02-27

Publications (2)

Publication Number Publication Date
WO2020132494A2 WO2020132494A2 (fr) 2020-06-25
WO2020132494A3 true WO2020132494A3 (fr) 2020-07-23

Family

ID=71101647

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2019/067942 Ceased WO2020132494A2 (fr) 2018-12-21 2019-12-20 Procédés de pronostic, de diagnostic et de traitement du cancer gastrique

Country Status (1)

Country Link
WO (1) WO2020132494A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116179691A (zh) * 2022-09-07 2023-05-30 苏州大学附属第一医院 一种胃癌组合标志物及标志物模型的建立方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120214690A1 (en) * 2006-01-05 2012-08-23 The Ohio State University Methods for Diagnosing Colon, Stomach, Prostate and Pancreas Cancer Using miR-223
US20170233822A1 (en) * 2014-08-07 2017-08-17 Agency For Science, Technology And Research MicroRNA Biomarker for the Diagnosis of Gastric Cancer
WO2018165532A1 (fr) * 2017-03-10 2018-09-13 Baylor Research Institute Procédés de diagnostic et de traitement du cancer gastrique au moyen d'expression de miarn

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120214690A1 (en) * 2006-01-05 2012-08-23 The Ohio State University Methods for Diagnosing Colon, Stomach, Prostate and Pancreas Cancer Using miR-223
US20170233822A1 (en) * 2014-08-07 2017-08-17 Agency For Science, Technology And Research MicroRNA Biomarker for the Diagnosis of Gastric Cancer
WO2018165532A1 (fr) * 2017-03-10 2018-09-13 Baylor Research Institute Procédés de diagnostic et de traitement du cancer gastrique au moyen d'expression de miarn

Also Published As

Publication number Publication date
WO2020132494A2 (fr) 2020-06-25

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