WO2021005247A1 - Dispositif d'étalonnage de concentration de gaz automatique, procédé d'étalonnage automatique d'un capteur de concentration de gaz et procédé de surveillance d'une concentration de gaz - Google Patents

Dispositif d'étalonnage de concentration de gaz automatique, procédé d'étalonnage automatique d'un capteur de concentration de gaz et procédé de surveillance d'une concentration de gaz Download PDF

Info

Publication number
WO2021005247A1
WO2021005247A1 PCT/ES2019/070482 ES2019070482W WO2021005247A1 WO 2021005247 A1 WO2021005247 A1 WO 2021005247A1 ES 2019070482 W ES2019070482 W ES 2019070482W WO 2021005247 A1 WO2021005247 A1 WO 2021005247A1
Authority
WO
WIPO (PCT)
Prior art keywords
gas
sensor
gas concentration
concentration
coefficient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/ES2019/070482
Other languages
English (en)
Spanish (es)
Inventor
Jesús MUÑOZ SANZ
Rigoberto Perez de Alejo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Noxtec Development SL
Original Assignee
Noxtec Development SL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Noxtec Development SL filed Critical Noxtec Development SL
Priority to PCT/ES2019/070482 priority Critical patent/WO2021005247A1/fr
Publication of WO2021005247A1 publication Critical patent/WO2021005247A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/0004Gaseous mixtures, e.g. polluted air
    • G01N33/0006Calibrating gas analysers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/021Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes operated by electrical means
    • A61M16/022Control means therefor
    • A61M16/024Control means therefor including calculation means, e.g. using a processor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/08Bellows; Connecting tubes ; Water traps; Patient circuits
    • A61M16/0816Joints or connectors
    • A61M16/0841Joints or connectors for sampling
    • A61M16/085Gas sampling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/08Bellows; Connecting tubes ; Water traps; Patient circuits
    • A61M16/0808Condensation traps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/12Preparation of respiratory gases or vapours by mixing different gases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/20Valves specially adapted to medical respiratory devices
    • A61M16/201Controlled valves
    • A61M16/202Controlled valves electrically actuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0027Accessories therefor, e.g. sensors, vibrators, negative pressure pressure meter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/003Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
    • A61M2016/0033Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/1005Preparation of respiratory gases or vapours with O2 features or with parameter measurement
    • A61M2016/102Measuring a parameter of the content of the delivered gas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/1005Preparation of respiratory gases or vapours with O2 features or with parameter measurement
    • A61M2016/102Measuring a parameter of the content of the delivered gas
    • A61M2016/1035Measuring a parameter of the content of the delivered gas the anaesthetic agent concentration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/02Gases
    • A61M2202/0208Oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/02Gases
    • A61M2202/0266Nitrogen (N)
    • A61M2202/0275Nitric oxide [NO]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3331Pressure; Flow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/70General characteristics of the apparatus with testing or calibration facilities
    • A61M2205/702General characteristics of the apparatus with testing or calibration facilities automatically during use

Definitions

  • the present invention relates to an automatic gas concentration calibration device, a method for automatically calibrating a gas concentration sensor and a method for monitoring a gas concentration.
  • Known gas concentration monitors use multiple sensors based on electrochemical cells to measure the concentration of the gas passing through the sensor. More specifically, a voltage is generated by a chemical reaction between the gas and the cell's electrodes, this voltage being proportional to the gas concentration.
  • Alternatives to electrochemical cell-based monitors include electro-fluorescence-based monitors.
  • Such gas concentration sensors are commonly used to determine the concentration of medical gases that are delivered from a medical device to a patient undergoing treatment.
  • a disadvantage of using such cells to measure gas concentration is that the electrochemical reaction breaks down the electrodes, resulting in a change in the electrical and chemical properties of the cell and therefore the measured concentration, which generally It can make an electrochemical cell lose more than 3% accuracy per month.
  • environmental conditions such as temperature, relative pressure and humidity can also affect the measured concentration. As a result, such gas sensors require periodic calibration to ensure that the measured gas concentration is accurate.
  • a method for automatically calibrating a gas concentration sensor that can function to produce a sensor output representing a gas concentration, comprising the steps of supplying a first reference gas, which has a known first reference gas concentration, to the gas concentration sensor, which measures the first sensor output of the gas concentration sensor, which supplies a second reference gas having the second gas concentration known reference to the gas concentration sensor, which measures a second sensor output from the gas concentration sensor and determines a sensor coefficient that defines the relationship between the gas concentration and the sensor output based on the first and second known reference gas concentrations and the first and second sensor outputs.
  • an automatic gas concentration calibration device comprising a first reference line, which can be operatively connected to a first reference gas of known gas concentration, and a second reference line. operably connected to a second reference gas of known gas concentration, a processor operable to measure a first sensor output of a first known reference gas supplied to the gas concentration sensor, measure a second sensor output of a second known reference gas supplied to the gas concentration sensor, and determining a sensor coefficient that defines the relationship between the gas concentration and the sensor output based on the first and second known reference gas concentrations and the first and second sensor outputs, and a valve assembly that can work to automatically switch Mainly supplying gas to the gas sensor between the first and second reference gas to allow the sensor output to be measured for the first and second reference gas.
  • Figure 1 reflects a schematic diagram showing a gas calibration device according to one aspect of the present invention.
  • Figure 2 reflects a pneumatic diagram showing the gas calibration device of Figure 1 with a sample gas of unknown concentration being supplied.
  • Figure 3 reflects a pneumatic diagram showing the gas calibration device of Figure 1 with a reference gas of known concentration from the supplied atmosphere.
  • Figure 4 reflects a pneumatic diagram showing the gas calibration device of Figure 1 with a reference gas of known concentration from a supplied calibration cylinder.
  • a gas concentration monitoring system 10 comprises a gas concentration measuring device 50 having a first reference conduit in the form of a calibration conduit 13, a sampling conduit 14 and a second sampling conduit. referenced in the form of a room duct 16, a first exhaust duct 37, and a second exhaust duct 42.
  • the gas concentration measuring device 50 further comprises a plurality of gas concentration sensors 18 in the form of three electrochemical sensors 18a, 18b, 18c, which can be connected to a gas calibration cylinder 12 through calibration conduit 13 and a pump conduit 15, to a ventilation circuit V, as is known in the art, through sampling conduit 14, a common connecting conduit 17 and pump conduit 15 , and to the atmosphere through the room duct 16, the common connection duct 17 and the pump duct 15.
  • Each sensor of the three gas concentration sensors 18a, 18b, 18c measures the concentration of supplied gases, for example oxygen (O2), nitric oxide (NO) and nitrogen dioxide (NO2) as will be described below. It will be understood that the number of sensors required corresponds to the number of gases whose concentration is being measured.
  • supplied gases for example oxygen (O2), nitric oxide (NO) and nitrogen dioxide (NO2)
  • a ventilator (not shown) is connected to a patient via an inspiratory limb and an expiratory limb (both not shown).
  • the inspiratory limb includes a connector to allow the injection of nitric oxide and another connector that allows the connection of the sampling line 14. Between the two connectors, the air mixes with the oxygen coming from the ventilator, which generates nitrogen dioxide so that the patient receives a homogeneous mixture.
  • Calibration gas cylinder 12 contains a first reference gas that can be connected to calibration conduit 13 to allow calibration of gas sensors 18.
  • Gas calibration cylinder 12 contains a mixture of gases chosen to represent the gases to be supplied to allow treatment of the patient.
  • the calibration gas cylinder 12 will comprise nitric oxide (NO) and nitrogen dioxide (NO2), as nitric oxide will react with oxygen in the inspiratory limb to form dioxide. nitrogen, and therefore its concentration needs to be measured.
  • Ambient conduit 16 is connected to atmosphere to allow calibration of gas sensors 18.
  • the sampling line 14 is gaseously connected to the ventilation circuit V, which contains a sample gas of unknown gas concentration.
  • the gas concentration measuring device 50 includes a valve assembly comprising a first solenoid valve 20 and a second solenoid valve 22.
  • the first solenoid valve 20 connects the ambient conduit 16 to the common connecting conduit 17, and connects the sampling conduit 14 to the common connecting conduit 17, to allow switching of the gas supply to the common connecting conduit 17, and ultimately , to the three sensors 18a, 18b, 18c, between the atmosphere and the ventilation circuit V for calibration and monitoring purposes as described below.
  • the second solenoid valve 22 connects the common connection conduit 17 and the calibration conduit 13 to the pump conduit 15, to allow the switching of the gas supply to the common connection conduit 17, and finally to the three electrochemical sensors 18a, 18b, 18c between one of the atmosphere and the ventilation circuit V selected by the first solenoid valve 20, and the calibration 13.
  • the pump 24 is positioned in the pump conduit 15 to pump gas from the ventilation circuit, the atmosphere or the calibration gas 12, as selected by the first 20 and the second 22 solenoid valves, to the concentration sensors of gas 18a, 18b, 18c.
  • An optional water trap 26 is provided in ambient conduit 16 and sampling conduit 14 to remove condensation from the conduits and prevent contamination of the gas sensors.
  • a first flow regulator 28 or proportional valve is provided in the calibration conduit 13 between the calibration gas 12 and the second solenoid valve 22, and a second flow regulator 32 or proportional valve is provided downstream of the gas sensors 18a, 18b, 18c to control the flow rate and pressure of the gas supplied to the sensors 18a, 18b, 18c to allow the calibration of the gas sensors 18 in the most accurate manner.
  • a flow sensor 36 and a pressure sensor 38 are provided downstream of the sensors 18a, 18b, 18c in the first exhaust conduit 37, which further includes a one-way valve 40.
  • a one-way valve 30 is provided between the second solenoid valve 22 and the pump 24, so that the second exhaust conduit 42 can release any excess calibration gas to ensure stable pressure and flow if the flow rate or pressure is too high.
  • the one-way valve can be replaced with a solenoid valve.
  • the second exhaust conduit 42 includes an optional flow sensor 34 positioned downstream of the one-way valve 30 for monitoring the flow rate of the calibration gas.
  • the one-way valve 30 could be an actuated solenoid valve in conjunction with the solenoid valves 20, 22.
  • the gas concentration measuring device 50 includes a processor 60 (shown schematically in Figure 1), which operates the switching of the first and second solenoid valves 20,22 in response to programmed instructions from both manual as well as automatic to allow calibration of gas sensors 18a, 18b, 18c and / or monitoring of gas concentration.
  • a processor 60 shown schematically in Figure 1
  • gas concentration calibration device 50 The operation of the gas concentration calibration device 50 is described below, which first requires calibration of the gas sensors 18a,
  • the processor 60 instructs the pump 24 to turn on, and switches the first solenoid valve 20 to supply gas from the atmosphere through the ambient conduit 16 to the common connection conduit 17 , and not gas from the sampling conduit 14.
  • the one-way valve 30 is closed and the second solenoid valve 22 is switched so that all supplied atmospheric gas passes through the common connecting conduit 17 and pump conduit 15, and flows past gas sensors 18a, 18b, 18c.
  • processor 60 records a first sensor output in the form of a first voltage measurement X1 for each gas sensor.
  • the voltage measurement X1 is measured by a voltmeter (not shown) connected to each of the sensors 18a, 18b, 18c.
  • the voltage can be measured by an analog-to-digital converter.
  • the processor 60 turns off the pump 24, switches the second solenoid valve 22 to supply gas from the calibration gas cylinder 12 to through the calibration line 13 to the common connection line 17, and switches the pump 24 again.
  • the one-way valve 30 and the first flow regulator 28 are controlled to ensure that any excess gas from released calibration is kept to a minimum. Control of the calibration gas is necessary to maintain a constant flow of gas to the sensors.
  • control is through the processor 60.
  • the gas from the calibration gas cylinder 12 flows through the gas sensors 18a, 18b, 18c, and once the pump 24 has been stabilized, processor 60 records a second sensor output in the form of a second voltage measurement X2 for each gas sensor.
  • the voltage measurement X2 is measured by the voltmeter connected to each of the sensors 18a, 18b, 18c.
  • the calibration phase is complete, and the processor 60 commands the first and second solenoid valves 20, 22 to switch the gas supply from atmosphere A and the calibration gas cylinder 12 to the gas sensors to supply the sample gas from the vent loop V.
  • Y is the gas concentration
  • X is the sensor output
  • n and n are parameters that define the sensor coefficient.
  • the sensor coefficients m and n are determined for each sensor 18a, 18b, 18c by solving Equation (1) above using the first and second voltage measurements X1, X2 that correspond to the known gas concentrations Y1, Y2, respectively.
  • Y1 from atmosphere is 21.9% and Y2 from calibration gas is 0%.
  • Y1 from atmosphere is 0% and Y2 from calibration gas is A%.
  • Y1 from atmosphere is 0% and Y2 from calibration gas is B%.
  • a relationship is then established between the sensor output X and the concentration of gas Y for each of sensors 18a, 18b, 18c, which can be used to determine an unknown gas concentration for O2, NO2, and NO when supplying gas to sensors 18a, 18b, 18c of sampling line 14 as shown described below.
  • the reference gases are the atmosphere and the calibration gas cylinder 12.
  • the reference gases could comprise two cylinders of calibration gas, without the need to use the atmosphere for calibration purposes.
  • the advantage of using the atmosphere as one of the reference gases is that the gas concentration is substantially constant and known, and secondly, it reduces the reliance on more expensive calibration gases.
  • Equation (1) defining the relationship between the measured voltage and the sensor output is a first order response.
  • the order of response is known either to the sensor manufacturer's specifications, from a previous study of the sensor during the design phase, or can be determined by plotting the sensor output for gases of different concentrations using the device of the present invention, with the curve of that graph indicating the order of the response.
  • the response may not be first order, and could, for example, be a second order relationship, in which case Equation (2) would be used below.
  • Y is the gas concentration
  • X is the sensor output
  • p, m and n are parameters that define the coefficient of the sensor.
  • the gas concentration measuring device 50 can be used to calculate the unknown concentration of the sample gas from the ventilation loop V using the measurement of the gas voltage of the gas. sample and determined sensor coefficient.
  • a known PID (proportional, integral, derivative) procedure is used to ensure that the flow rate and pressure of the sample gas are stable and that the flow and pressure conditions are the same for the calibration phase and when the concentration is measured sample gas.
  • the gas metering device 50 can be programmed such that, at periodic time intervals during the gas monitoring phase, for example every two days, the first solenoid valve 20 switches the gas supply of the normal gas monitoring. sampling line 16 (FIG. 2) to a reference gas, eg, atmospheric gas, to verify if the gas sensors require recalibration and a new sensor coefficient must be determined. More specifically, gas sensors are checked to see if the sensor output of a known reference gas corresponds to the known reference gas.
  • the reference gas is atmospheric gas, and the concentration of the atmospheric gas is determined as a function of sensor coefficients previously determined during the calibration phase and the measured sensor output.
  • the determined gas concentration of the atmospheric gas is then compared to the known atmospheric gas concentration to determine a difference of measured atmospheric gas concentration, and if the difference is below an acceptable predetermined threshold, for example 1% of the known atmospheric gas concentration, the sensor coefficient is considered to precisely define the relationship between sensor output and the gas concentration. That being the case, the gas supply to the sensors 18a, 18b, 18c is switched from atmospheric gas to the sample gas using the first solenoid valve 20, and the supply of the sample gas is monitored by the gas sensors.
  • an acceptable predetermined threshold for example 1% of the known atmospheric gas concentration
  • a new sensor coefficient is determined based on the calibration process described above. Once the new sensor coefficient is determined, the gas supply to the sensors 18a, 18b, 18c is switched from atmospheric gas to the sample gas using the first solenoid valve 20, and then the sample gas supply is monitored by the gas sensors with the gas concentration determined based on the new sensor coefficient and the sensor output.
  • the gas sensors can simply be recalibrated to a fixed time interval (equal to or different from the interval time used in the verification process described above). It will be understood that the verification process avoids unnecessary calibration if it is not required, however there may be circumstances where gas sensors require automatic calibration without the need for an additional verification phase, for example if there is a certain degree of certainty that the sensor coefficient will have changed.
  • the gas sensors can be recalibrated in response to a change. in environmental conditions that could impact the accuracy of the gas sensors, for example a change in temperature or pressure, or some other actuator, such as after the gas sensor has been moved or reassembled after maintenance. Therefore, it will be appreciated that the measurement device 50 of the present invention not only allows automatic calibration of gas sensors, but also allows the calibration to be verified during normal gas monitoring to determine if the calibration is correct. and, if not, perform a recalibration.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Emergency Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Pulmonology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Combustion & Propulsion (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)

Abstract

L'invention concerne un dispositif d'étalonnage de concentration de gaz automatique qui comprend un premier conduit de référence qui peut être connecté fonctionnellement à un premier gaz de référence de concentration de gaz connue, et un deuxième conduit de référence qui peut être connecté fonctionnellement à un deuxième gaz de référence de concentration de gaz connue, qui détermine un coefficient du capteur qui définit la relation entre la concentration de gaz et la sortie du capteur; un procédé pour étalonner automatiquement un capteur de concentration de gaz qui peut fonctionner pour produire une sortie de capteur qui représente une concentration de gaz; et un procédé de surveillance d'une concentration de gaz.
PCT/ES2019/070482 2019-07-10 2019-07-10 Dispositif d'étalonnage de concentration de gaz automatique, procédé d'étalonnage automatique d'un capteur de concentration de gaz et procédé de surveillance d'une concentration de gaz Ceased WO2021005247A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/ES2019/070482 WO2021005247A1 (fr) 2019-07-10 2019-07-10 Dispositif d'étalonnage de concentration de gaz automatique, procédé d'étalonnage automatique d'un capteur de concentration de gaz et procédé de surveillance d'une concentration de gaz

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/ES2019/070482 WO2021005247A1 (fr) 2019-07-10 2019-07-10 Dispositif d'étalonnage de concentration de gaz automatique, procédé d'étalonnage automatique d'un capteur de concentration de gaz et procédé de surveillance d'une concentration de gaz

Publications (1)

Publication Number Publication Date
WO2021005247A1 true WO2021005247A1 (fr) 2021-01-14

Family

ID=67956802

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/ES2019/070482 Ceased WO2021005247A1 (fr) 2019-07-10 2019-07-10 Dispositif d'étalonnage de concentration de gaz automatique, procédé d'étalonnage automatique d'un capteur de concentration de gaz et procédé de surveillance d'une concentration de gaz

Country Status (1)

Country Link
WO (1) WO2021005247A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112557606A (zh) * 2021-02-28 2021-03-26 中国工程物理研究院核物理与化学研究所 一种专用于气体探测器性能参数测定的辅助装置
CN113588883A (zh) * 2021-08-02 2021-11-02 中科三清科技有限公司 一种进行自动校准的环境空气质量监测装置
GB2631083A (en) * 2023-06-12 2024-12-25 Crowcon Detection Instruments Ltd Cross calibration by automatic gas detectors

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5329804A (en) * 1992-10-16 1994-07-19 Abbott Laboratories Calibration system and method for calibrating a blood gas sensor
US20110120206A1 (en) * 2008-02-19 2011-05-26 Gavin Troughton Methods of calibrating a sensor in a patient monitoring system

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5329804A (en) * 1992-10-16 1994-07-19 Abbott Laboratories Calibration system and method for calibrating a blood gas sensor
US20110120206A1 (en) * 2008-02-19 2011-05-26 Gavin Troughton Methods of calibrating a sensor in a patient monitoring system

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
GREG SHIRES: "Q & A: on Calibration & Bump/Response Testing of Gas Detection Instruments", 1 December 2017 (2017-12-01), XP055673605, Retrieved from the Internet <URL:https://www.cacgas.com.au/blog/q-a-on-calibration-bump/response-testing-of-gas-detection-instruments> [retrieved on 20200304] *
JOHN T. EVANS ET AL: "Automated Calibration of Electrochemical Oxygen Sensors for Use in Compost Bedded Pack Barns", TRANSACTIONS OF THE ASABE, vol. 60, no. 3, 2017, pages 957 - 962, XP055673706, DOI: 10.13031/trans.12099 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112557606A (zh) * 2021-02-28 2021-03-26 中国工程物理研究院核物理与化学研究所 一种专用于气体探测器性能参数测定的辅助装置
CN113588883A (zh) * 2021-08-02 2021-11-02 中科三清科技有限公司 一种进行自动校准的环境空气质量监测装置
GB2631083A (en) * 2023-06-12 2024-12-25 Crowcon Detection Instruments Ltd Cross calibration by automatic gas detectors

Similar Documents

Publication Publication Date Title
US11285280B2 (en) Intelligent gas source management
WO2021005247A1 (fr) Dispositif d&#39;étalonnage de concentration de gaz automatique, procédé d&#39;étalonnage automatique d&#39;un capteur de concentration de gaz et procédé de surveillance d&#39;une concentration de gaz
US8776791B2 (en) Respirator and method for calibrating flow rate measuring component thereof
EP2756279B1 (fr) Contrôle de fuites de gaz fondé sur la pression
US9494947B2 (en) Pressure type flow control system with flow monitoring
US9205211B2 (en) Respirator
WO2020123594A1 (fr) Procédés et systèmes destinés à un module de distribution de gaz médical
US20110132366A1 (en) Ventilator Respiratory Gas Accumulator With Purge Valve
CN118236595B (zh) 用于呼吸机的呼气压力检测方法、校准方法及装置、设备
JP2006017695A (ja) 校正方法およびこれを利用したジルコニア式酸素濃度計
CA3063026A1 (en) Apparatus for remote manual and automated testing and calibration of toxic gas sensors installed in the field
CN116059490B (zh) 压力传感器自校正方法、系统、呼吸机、控制器及存储器
CN113134149B (zh) 用于设定麻醉剂浓度的麻醉剂计量设备和方法
KR20100024674A (ko) 가스측정기 멀티 교정시스템
KR101647228B1 (ko) 습도 측정 장치 및 이의 측정 정도 향상 방법
CN117982773A (zh) 流量检测控制方法、系统、呼吸机、控制器及存储器
EP3711804B1 (fr) Machine d&#39;anesthésie et procédé d&#39;étalonnage
CN117347568A (zh) 一种呼吸机检测仪氧气浓度校准装置及方法
CN118566444B (zh) 光合速率检测设备和方法
EP3761147B1 (fr) Dispositif pour mesurer la composition de l&#39;air médicinal
CN113134150A (zh) 带有测量单元的麻醉剂计量装置
JP2006516412A (ja) 気体の供給を監視し患者へ気体を送出するためのシステムおよび方法
CN222364963U (zh) 一种呼吸机检测仪氧气浓度校准装置
CBET Multigas Monitors: Overview and Preventive Maintenance Essentials
Lacouture et al. A Compact, Data-Logging Breath-Gas Analyzer

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 19769194

Country of ref document: EP

Kind code of ref document: A1

DPE1 Request for preliminary examination filed after expiration of 19th month from priority date (pct application filed from 20040101)
122 Ep: pct application non-entry in european phase

Ref document number: 19769194

Country of ref document: EP

Kind code of ref document: A1