WO2022037007A1 - Tube d'échantillonnage - Google Patents
Tube d'échantillonnage Download PDFInfo
- Publication number
- WO2022037007A1 WO2022037007A1 PCT/CN2021/072195 CN2021072195W WO2022037007A1 WO 2022037007 A1 WO2022037007 A1 WO 2022037007A1 CN 2021072195 W CN2021072195 W CN 2021072195W WO 2022037007 A1 WO2022037007 A1 WO 2022037007A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- sampling
- tube
- tube body
- swab
- fixing member
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
Definitions
- the present disclosure relates to the field of medical devices, and in particular, to a sampling tube.
- the existing disposable virus sampler includes a sampling swab and a sampling tube, and the sampling tube is filled with a preservation solution.
- the medical staff uses the sampling swab for sampling, so that the sampling head of the sampling swab carries the sample, and then the end of the sampling swab with the sampling head is inserted into the sampling tube, and the sampling swab is broken according to the breaking point. Part of the sampling head falls freely into the preservation solution.
- the sampling swab is placed in the sampling tube at an irregular angle, and then the cap of the sampling tube is tightened to seal and store, so that the sample on the sampling head is fully dissolved in the preservation solution, and finally transported into the laboratory testing process.
- the existing laboratory testing processes mostly use automatic extractors and automatic sample adding devices to extract and add samples.
- Both the automatic extractor and the automatic sampler are high-precision and high-sensitivity instruments, and the sampling swabs are irregularly placed in the sampling tube.
- the previous process needs to increase the manpower.
- the sampling swab is manually taken out of the sampling tube to leave room for operation in the sampling tube. After that, the sampling tube without the sampling swab is used on the machine for automatic extraction. or sample addition.
- virus detection such as nucleic acid detection of new coronary pneumonia
- the operation of manually processing the sampling cotton tip increases the risk of infection, and also increases the cost of labor and protective equipment.
- the purpose of the embodiments of the present disclosure is to provide a sampling tube, which can effectively reduce the risk of infection, simplify the detection process, improve the detection efficiency, and reduce the labor cost and the cost of protective equipment.
- the present disclosure provides a sampling tube, the sampling tube includes a tube body and a fixing member, the fixing member is disposed in the tube body and configured to fix the sampling swab in a predetermined position in the tube body , so that the operating space is reserved in the tube.
- the medical and nursing testing personnel use the sampling swab for sampling, so that after the sampling head of the sampling swab carries the sample, the end of the sampling swab with the sampling head is inserted into the sampling tube, and The sampling swab is fixed by the fixing member in the sampling tube, and then the sampling swab is pressed laterally to be broken near the breaking point, so that the sampling swab left in the sampling tube can be fixed in a predetermined position, and the sampling swab in the predetermined position It is placed in the sampling tube according to the preset arrangement, and the operation space is reserved for the subsequent automatic extraction or automatic sample addition.
- the sampling tube with the sampling swab can be directly connected to the machine for automatic extraction and sample addition operations, omitting the need for manual processing of the sampling swab.
- the operation steps reduce the high-risk infection links, which can effectively reduce the infection risk, simplify the detection process, improve the automation rate, improve the detection efficiency, and reduce the labor cost and the cost of protective equipment.
- the fixing member is fixed on the inner wall of the tube body, and a clamping groove configured to hold the sampling swab is opened on the fixing member.
- the sampling swab is fixed by holding the sampling swab in the card slot, the structure is simple, and the sampling swab can be fixed.
- the operation of fixing the swab is also relatively simple. It is only necessary to snap the complete sampling swab into the card slot, and then break the sampling swab, and then the sampling swab part with the sampling head can be fixed in the predetermined position in the sampling tube.
- the fixing member includes an upper end surface facing the same direction as the nozzle of the pipe body, a lower end surface opposite to the nozzle opening of the pipe body, and an upper end surface opposite to the nozzle of the pipe body.
- the inner wall of the pipe body is opposite to the fixing surface, the upper end surface is located between the nozzle and the lower end surface, the clamping groove is opened on the fixing surface, and the clamping groove extends from the upper end surface.
- the lower end surface penetrates the fixing member and penetrates the fixing surface in the lateral direction.
- the card slot is opened on the fixed surface opposite to the inner wall of the tube body, and the two ends penetrate through the upper end surface and the lower end surface respectively, that is, the card slot is opened horizontally.
- the sampling swab is clamped into the card slot, and then the sampling swab is pressed laterally to be broken near the breaking point, the operation is convenient and the structure is simple.
- the sampling swab is provided with a breaking point, and the distance from the end face of the sampling swab close to one end of the sampling head to the breaking point is greater than or equal to the tube bottom of the tube body to the upper part of the fixing member.
- the distance between the end faces is less than or equal to the distance from the bottom of the tube body to the mouth of the tube, so that after the complete sampling swab is stuck in the slot, the breaking point of the sampling swab is located between the mouth of the tube body and the upper end face of the fixture , which can facilitate the breaking operation of the sampling swab.
- the clamping groove extends in a direction parallel to the axis of the pipe body.
- the card slot is set to extend parallel to the axis direction of the tube body, so that the sampling swab is placed in the tube body along the direction parallel to the axis direction of the tube body, that is, the sampling swab is placed vertically in the tube body, Furthermore, enough operating space for the automatic extraction machine or the automatic sample adding machine to operate can be reserved in the tube body.
- the cross-section of the card slot is a circle with a gap
- the diameter of the circle is equal to the diameter of the sampling swab
- the gap corresponds to the diameter of the sampling swab.
- the length of the chord is less than the diameter of the sampling swab.
- the inner diameter of the clamping slot is set equal to the diameter of the sampling swab, so that the sampling swab can be firmly clamped in the tube body, preventing the sampling swab from detaching from the fixing member due to external shaking and collision during transportation. , and leave the predetermined position.
- the ratio of the distance from the lower end surface of the fixing member to the bottom of the pipe body to the length of the pipe body is 1:2-3: 4.
- the ratio of the distance between the lower end face of the fixing piece and the bottom of the pipe body to the length of the pipe body is set to be 1:2-3:4, that is, the fixing piece is set close to the nozzle position of the pipe body, which is convenient Fixing and breaking of sampling swabs.
- the number of the fixing members is multiple.
- a plurality of fixing parts are arranged in the tube body, so that a plurality of sampling swabs can be accommodated and fixed in the tube body at the same time, that is, the sampling tube can be applied to the method of mixed sampling, and the manual collection of multiple swabs is saved.
- the operation of taking the sampling swabs in the sampling tube reduces the high-risk infection links, thereby effectively reducing the infection risk, simplifying the detection process, improving the automation rate, and cooperating with the mixed sampling method to effectively improve the detection efficiency and reduce labor costs and protective equipment costs.
- the fixing member is an annular body disposed along the inner wall of the pipe body, and the annular body is provided with a plurality of the snap grooves.
- the fixing member is set as an annular body arranged along the inner wall of the tube body, and a plurality of clamping grooves are opened on the annular body, and the plurality of clamping grooves can hold a plurality of sampling swabs, so that the sampling tube can be It is applied to the mixed sampling method, and the operation of manually taking the sampling swabs in the sampling tube for many times is omitted, which reduces the high-risk infection link, thereby effectively reducing the infection risk, simplifying the detection process, improving the automation rate, and matching the mixed sampling method. Effectively improve detection efficiency and reduce labor costs and protective equipment costs.
- annular protrusion is provided on the bottom of the pipe body, and the annular protrusion cooperates with the inner wall of the pipe body to form an annular groove, and the annular groove cooperates with the inner wall of the pipe body to form an annular groove.
- a sampling head configured to secure the sampling swab.
- an annular groove is set at the bottom of the tube to fix the sampling head of the sampling swab, and the sampling swab is placed to offset to the center, which further stabilizes the sampling swab and ensures the stability of the operating space.
- the sampling tube further includes a tube cover, and the tube cover is configured to cover the mouth of the tube body to seal the tube body.
- the tube mouth of the tube body is sealed with a tube cover, and the samples are uniformly sealed.
- the plurality of fixing members are arranged in a circumferential array along the inner wall of the pipe body.
- a plurality of card grooves on the fixing member are arranged in a circumferential array.
- a breaking point is set on the sampling swab, and the distance from the end face of the sampling swab close to one end of the sampling head to the breaking point is greater than or equal to all
- the distance from the bottom of the pipe of the pipe body to the upper end surface of the fixing member is less than or equal to the distance from the bottom of the pipe of the pipe body to the mouth of the pipe.
- the material of the fixing member is the same as the material of the pipe body.
- the material of the fixing member is different from the material of the pipe body.
- a method for using the sampling tube comprising the steps of:
- the whole sampling swab is pressed laterally so that the whole sampling swab breaks near the breaking point.
- the above-mentioned method for using the sampling tube according to any one of the above-mentioned implementation manners further includes: sealing the mouth of the tube body with a tube cover.
- FIG. 1 is a cross-sectional view of a sampling tube according to an embodiment of the present disclosure
- FIG. 2 is a structural diagram of a sampling tube according to an embodiment of the present disclosure
- FIG. 3 is a structural diagram of a fixing member according to an embodiment of the present disclosure.
- Icon 100-tube body; 110-tube mouth; 120-tube bottom; 200-sampling swab; 210-sampling head; 220-breaking point; 300-fixing part; Lower end face; 340-fixed surface; 400-annular protrusion; 500-annular groove; 600-pipe cover.
- FIG. 1 is a cross-sectional view of a sampling tube provided by an embodiment of the present disclosure
- FIG. 2 is a structural diagram of a sampling tube provided by an embodiment of the present disclosure
- FIG. 3 is an implementation of the present disclosure
- a structural diagram of a fixing member 300 is provided.
- the present disclosure provides a sampling tube.
- the sampling tube may include a tube body 100 and a fixing member 300.
- the fixing member 300 is disposed in the tube body 100 and is configured to fix the sampling swab 200 at a predetermined position in the tube body 100, so that the An operation space is reserved in the pipe body 100 .
- sampling swab 200 refers to the part of the complete sampling swab 200 with the sampling head 210 that falls freely into the sampling tube after being broken.
- the medical and nursing personnel use the sampling swab 200 for sampling, so that after the sampling head 210 of the sampling swab 200 carries the sample, the end of the sampling swab 200 with the sampling head 210 is inserted into the sampling tube, The sampling swab 200 is fixed by the fixing member 300 in the sampling tube, and then the sampling swab 200 is pressed laterally to be broken near the breaking point 220, so that the sampling swab 200 left in the sampling tube can be fixed in a predetermined position, The sampling swab 200 at a predetermined position is placed in the sampling tube according to a preset arrangement, so as to reserve an operating space for subsequent automatic extraction or automatic sample addition.
- sampling swab 200 when entering the laboratory testing process, there is no need to manually take out the sampling swab 200 from the sampling tube, and the sampling tube with the sampling swab 200 can be directly loaded into the machine for automatic extraction and sample addition operations, omitting manual processing of sampling swabs.
- the operation steps of the sub-200 reduce the high-risk infection links, which can effectively reduce the infection risk, simplify the detection process, improve the automation rate, improve the detection efficiency, and reduce the labor cost and the cost of protective equipment.
- the sampling tube may further include a tube cover 600 , and the tube cover 600 is configured to cover the nozzle 110 of the tube body 100 to seal the tube body 100 .
- the tube cover 600 is used to seal the mouth 110 of the tube body 100 to perform unified sealing management on the sample.
- the material of the above-mentioned tube body 100 and the tube cover 600 can be selected from food-grade PP (Polypropylene, polypropylene plastic) or other materials that meet medical requirements.
- the pipe cover 600 and the pipe body 100 are sealedly connected by screw fitting, and the pipe cover 600 and the pipe body 100 may also be sealedly connected by means of snap-fit, which is not limited in the embodiment of the present disclosure.
- the outer diameter of the above-mentioned pipe body 100 can be reasonably designed to meet the models of different extraction machines and sample loading machines.
- the fixing member 300 is fixed on the inner wall of the tube body 100, and the fixing member 300 is provided with a clamping groove 310 configured to hold the sampling swab.
- the sampling swab 200 is fixed by the clamping slot 310 clamping the sampling swab 200
- the structure is simple, and the operation of fixing the sampling swab 200 is also relatively simple. It is only necessary to snap the complete sampling swab 200 into the slot 310, and then break the sampling swab 200, and then the sampling head 210 can be collected.
- the swab 200 is partially fixed in a predetermined position within the sampling tube.
- the material of the fixing member 300 may be various, and the material of the fixing member 300 may be the same as the material of the tube body 100 , or may be different from the material of the tube body 100 .
- the fixing member 300 may include an upper end surface 320 facing the same direction as the nozzle 110 of the pipe body 100 , a lower end surface 330 opposite to the nozzle opening of the pipe body 100 , and opposite to the inner wall of the pipe body 100
- the upper end surface 320 is located between the nozzle 110 and the lower end surface 330, the clamping groove 310 is opened on the fixing surface 340, and the clamping groove 310 penetrates the fixing member 300 from the upper end surface 320 to the lower end surface 330 and penetrates in the transverse direction. the fixed surface 340 .
- the clamping slot 310 can be opened on the fixing surface 340 opposite to the inner wall of the pipe body 100 and penetrate the fixing member 300 from the upper end surface 320 to the lower end surface 330 and penetrate the fixing surface 340 in the lateral direction, that is, the clamping slot 310 is opened vertically through the fixing member 300 and horizontally through the fixing surface 340.
- the sampling swab 200 may be provided with a breaking point 220, and the distance from the end face of the sampling swab 200 close to one end of the sampling head 210 to the breaking point 220 is greater than or equal to the distance from the tube bottom 120 of the tube body 100 to the fixing member
- the distance from the upper end face 320 of the 300 is less than or equal to the distance from the bottom 120 of the tube body 100 to the mouth 110, insert the complete sampling swab into the tube body 100, so that the breaking point 220 of the complete sampling swab is located in the tube body
- the breaking operation of the sampling swab 200 can be facilitated.
- Swab 200 causes it to break near breaking point 220 .
- the clamping groove 310 extends in a direction parallel to the axis of the pipe body 100 .
- the clamping slot 310 is set to extend parallel to the axial direction of the tube body 100 , so that the sampling swab 200 is placed in the tube body 100 along the direction parallel to the axial direction of the tube body 100 , that is, the sampling swab 200 It is placed vertically in the tube body 100, so that enough operating space for the automatic extraction machine or the automatic sample adding machine to operate can be reserved in the tube body 100.
- the cross section of the clip slot 310 may be substantially a circle with a gap, the diameter of the circle is equal to the diameter of the sampling swab 200 , and the length of the chord corresponding to the gap is smaller than the diameter of the sampling swab 200 . diameter.
- the inner diameter of the clamping slot 310 is set equal to the diameter of the sampling swab 200, so that the sampling swab 200 can be stably clamped in the tube body 100 to prevent sampling due to external shaking and collision during transportation.
- the swab 200 is released from the fixing member 300 and is released from a predetermined position.
- the ratio of the distance from the lower end surface 330 of the fixing member 300 to the pipe bottom 120 of the pipe body 100 to the length of the pipe body 100 is 1:2-3:4.
- the ratio of the distance from the lower end surface 330 of the fixing member 300 to the tube bottom 120 of the tube body 100 to the length of the tube body 100 is set to be 1:2-3:4, that is, the fixing member 300 is limited to be close to the tube body 100
- the position of the nozzle 110 is set to facilitate operations such as fixing and breaking the sampling swab 200 .
- the mixed sampling set includes a plurality of sampling swabs 200, a sampling tube and a preservation solution.
- the specific mixed sampling process is as follows: medical staff take a single sampling swab 200 to sample separately, and after each sampling is completed, put it into a sampling tube and put it in the preservation solution for immersion, complete multiple sampling actions, and make corresponding collection records. , After the mixed sampling is completed, it is transported to the laboratory through the sample storage box to enter the testing process, and then the lid is opened for testing.
- sampling swabs 200 are placed in a storage tube irregularly, so that no extraction head or sample addition head of a subsequent automatic extractor or automatic sampler is reserved in the sampling tube to extend into the sampling tube.
- the tube is an operation space for extraction or sample addition, so the sampling swab 200 in the sampling tube needs to be manually taken out before automatic extraction or sample addition. Manually taking the sampling swab 200 in the sampling tube many times greatly increases the risk of infection, reduces the detection efficiency, and increases labor costs and protective equipment costs.
- the number of the fixing members 300 is multiple.
- a plurality of fixing parts 300 may be arranged in the tube body 100, so that the tube body 100 can simultaneously accommodate and fix a plurality of sampling swabs 200, that is, the sampling tube can be applied to the method of mixed sampling,
- the operation of manually taking the sampling swabs 200 in the sampling tube for many times is omitted, which reduces the high-risk infection link, thereby effectively reducing the infection risk, simplifying the detection process, improving the automation rate, and effectively improving the detection efficiency with the mixed sampling method. Small labor cost and protective equipment cost.
- a plurality of fixing members 300 may be arranged in a circumferential array along the inner wall of the tube body 100 , so that the plurality of fixing members are arranged at the same height in the tube body 100 .
- a plurality of sampling swabs 200 are vertically disposed in the tube body 100 close to the inner wall of the tube body 100, and an operation space is formed in the middle to facilitate subsequent automatic extraction or sample addition operations.
- the fixing member 300 is an annular body disposed along the inner wall of the pipe body 100 , and a plurality of clamping grooves 310 are formed on the annular body.
- the fixing member 300 can be set as an annular body arranged along the inner wall of the tube body 100, and a plurality of clamping grooves 310 are formed on the annular body, and the plurality of clamping grooves 310 can hold a plurality of sampling swabs 200 makes the sampling tube applicable to the mixed sampling method, and saves the operation of manually taking the sampling swab 200 in the sampling tube many times, reduces the high-risk infection link, thereby effectively reduces the infection risk, simplifies the detection process, and improves automation. It can effectively improve the detection efficiency and reduce the labor cost and the cost of protective equipment.
- the plurality of clamping grooves 310 on the fixing member 300 of the annular body may be arranged in a circumferential array, and the plurality of sampling swabs 200 clamped in the clamping grooves 310 are vertically disposed near the inner wall of the tube body 100 .
- an operation space is formed in the middle to facilitate subsequent automatic extraction or sample addition operations.
- the tube bottom 120 of the tube body 100 may be provided with an annular protrusion 400, the annular protrusion 400 cooperates with the inner wall of the tube body 100 to form an annular groove 500, and the annular groove 500 is configured to fix the sampling swab 200 of the sampling head 210.
- the annular groove 500 is set on the bottom of the tube 120 to fix the sampling head 210 of the sampling swab 200, and the sampling swab 200 is placed to offset to the center, which further stabilizes the sampling swab 200 and ensures the operation space. stability.
- the purpose of the embodiments of the present disclosure is to provide a sampling tube, which can effectively reduce the risk of infection, simplify the detection process, improve the detection efficiency, and reduce the labor cost and the cost of protective equipment.
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- Life Sciences & Earth Sciences (AREA)
- Medical Informatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Sampling And Sample Adjustment (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
L'invention concerne un tube d'échantillonnage, comprenant un corps de tube (100) et un élément de fixation (300), l'élément de fixation (300) est disposé à l'intérieur du corps de tube (100) et est configuré pour fixer un tampon d'échantillonnage (200) dans une position prédéterminée à l'intérieur du corps de tube (100), de telle sorte qu'un espace de fonctionnement est réservé à l'intérieur du corps de tube (100). Le tube d'échantillonnage peut réduire efficacement le risque d'infection, simplifier le processus de test, améliorer l'efficacité de test et réduire les coûts de main-d'oeuvre et le coût de l'équipement de protection.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010834512.3A CN111839607B (zh) | 2020-08-18 | 2020-08-18 | 一种采样管 |
| CN202010834512.3 | 2020-08-18 | ||
| CN202021729121.7 | 2020-08-18 | ||
| CN202021729121.7U CN212630804U (zh) | 2020-08-18 | 2020-08-18 | 一种采样管 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO2022037007A1 true WO2022037007A1 (fr) | 2022-02-24 |
Family
ID=80322536
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/CN2021/072195 Ceased WO2022037007A1 (fr) | 2020-08-18 | 2021-01-15 | Tube d'échantillonnage |
Country Status (1)
| Country | Link |
|---|---|
| WO (1) | WO2022037007A1 (fr) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114891613A (zh) * | 2022-05-26 | 2022-08-12 | 深圳市疾病预防控制中心(深圳市卫生检验中心、深圳市预防医学研究所) | 一种免开盖移液病毒采样管及其使用方法 |
| CN114933955A (zh) * | 2022-06-13 | 2022-08-23 | 迪力扎提·伊力哈木 | 核酸检测用混检盖及核酸混检管 |
| CN115044462A (zh) * | 2022-05-23 | 2022-09-13 | 浙江天科高新技术发展有限公司 | 一种不开盖实现核酸扩增和检测的采样管及应用方法 |
| CN115093945A (zh) * | 2022-08-25 | 2022-09-23 | 山东华博基因工程有限公司 | 一种电化学病毒检测用采样器 |
| CN115778440A (zh) * | 2022-12-23 | 2023-03-14 | 重庆威科贝科技有限公司 | 采样设备 |
| WO2023196265A1 (fr) * | 2022-04-04 | 2023-10-12 | Life Technologies Corporation | Systèmes et procédés de collecte d'écouvillon |
| WO2023212764A3 (fr) * | 2022-05-02 | 2023-12-28 | Greiner Bio-One Gmbh | Dispositif de prélèvement d'échantillon, insert de fixation et ensemble de prélèvement d'échantillon et procédé de prélèvement d'échantillon |
| CN120078451A (zh) * | 2025-03-14 | 2025-06-03 | 中国人民解放军总医院海南医院 | 一种具有防止交叉污染结构的肠道菌群检测装置 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023196265A1 (fr) * | 2022-04-04 | 2023-10-12 | Life Technologies Corporation | Systèmes et procédés de collecte d'écouvillon |
| WO2023212764A3 (fr) * | 2022-05-02 | 2023-12-28 | Greiner Bio-One Gmbh | Dispositif de prélèvement d'échantillon, insert de fixation et ensemble de prélèvement d'échantillon et procédé de prélèvement d'échantillon |
| CN115044462A (zh) * | 2022-05-23 | 2022-09-13 | 浙江天科高新技术发展有限公司 | 一种不开盖实现核酸扩增和检测的采样管及应用方法 |
| CN114891613A (zh) * | 2022-05-26 | 2022-08-12 | 深圳市疾病预防控制中心(深圳市卫生检验中心、深圳市预防医学研究所) | 一种免开盖移液病毒采样管及其使用方法 |
| CN114933955A (zh) * | 2022-06-13 | 2022-08-23 | 迪力扎提·伊力哈木 | 核酸检测用混检盖及核酸混检管 |
| CN115093945A (zh) * | 2022-08-25 | 2022-09-23 | 山东华博基因工程有限公司 | 一种电化学病毒检测用采样器 |
| CN115778440A (zh) * | 2022-12-23 | 2023-03-14 | 重庆威科贝科技有限公司 | 采样设备 |
| CN120078451A (zh) * | 2025-03-14 | 2025-06-03 | 中国人民解放军总医院海南医院 | 一种具有防止交叉污染结构的肠道菌群检测装置 |
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