WO2022089292A1 - 珠串状部件及其制造方法和应用 - Google Patents

珠串状部件及其制造方法和应用 Download PDF

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Publication number
WO2022089292A1
WO2022089292A1 PCT/CN2021/125205 CN2021125205W WO2022089292A1 WO 2022089292 A1 WO2022089292 A1 WO 2022089292A1 CN 2021125205 W CN2021125205 W CN 2021125205W WO 2022089292 A1 WO2022089292 A1 WO 2022089292A1
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WO
WIPO (PCT)
Prior art keywords
expandable body
component
bead
beaded
stent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2021/125205
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English (en)
French (fr)
Inventor
吕怡然
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Accumedical Inc
Original Assignee
Accumedical Beijing Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN202011195618.XA external-priority patent/CN114848247A/zh
Priority claimed from CN202022479731.2U external-priority patent/CN214285319U/zh
Application filed by Accumedical Beijing Ltd filed Critical Accumedical Beijing Ltd
Priority to US18/034,387 priority Critical patent/US20230293324A1/en
Priority to ES21885019T priority patent/ES3049300T3/es
Priority to EP21885019.6A priority patent/EP4238540B8/en
Publication of WO2022089292A1 publication Critical patent/WO2022089292A1/zh
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/958—Inflatable balloons for placing stents or stent-grafts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2002/9534—Instruments specially adapted for placement or removal of stents or stent-grafts for repositioning of stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/962—Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve
    • A61F2/966—Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve with relative longitudinal movement between outer sleeve and prosthesis, e.g. using a push rod
    • A61F2002/9665—Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve with relative longitudinal movement between outer sleeve and prosthesis, e.g. using a push rod with additional retaining means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0004—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof adjustable
    • A61F2250/001—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof adjustable for adjusting a diameter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
    • A61F2250/0037—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in height or in length
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
    • A61F2250/0039—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in diameter

Definitions

  • the present disclosure relates to the field of interventional therapy, and in particular, to beaded components and methods of manufacture and applications thereof.
  • Vascular stents can be implanted into blood vessels through vascular interventional procedures for the treatment of various vascular disorders, such as blood flow directing techniques for treating hemangiomas, and vascular reconstruction techniques for treating vascular lumen stenosis or occlusion.
  • vascular stent When delivering a vascular stent into a blood vessel, a number of problems can be encountered. For example, after reaching the treatment site, the stent in a compressed state is subject to torsional stress that restricts the self-expansion of the stent. For another example, during stent delivery, the delivery system has poor passability, poor blood vessel compliance, and poor rotational coaxiality, making it difficult for the operator to precisely control the shape and position of the stent implant in the blood vessel during interventional operations.
  • the poor controllability of the above-mentioned delivery system for the stent implant reduces the efficiency of stent delivery, reduces the success rate of the stent reaching the diseased site, prolongs the operation time, and keeps the risk of operation failure and postoperative complications high.
  • the technical problems to be solved by the present disclosure are: on the one hand, the stent cannot be automatically released due to the influence of torsional stress; on the other hand, the operation during stent delivery is laborious and difficult, which reduces the stent delivery efficiency.
  • a beaded component including an expandable body and at least two shape-setting assemblies, each of the shape-setting components including a first component and a second component;
  • the first part has a cylindrical lumen in which a partial section of the expandable body is constricted to form a constricted section of the beaded part; or the first part having a cylindrical outer surface to which the inner surface of the partial section of the expandable body is fixedly connected to form a constricted section of the beaded member;
  • the second part is a tubular part, and the shrinking section is sleeved in the second part;
  • An expansion section of the bead string component is formed between two adjacent contraction sections.
  • the end of the second component is provided with a chamfered structure
  • the first part has a cylindrical inner cavity, and the shape of the first part is selected from a cylinder, a prism, a sphere or a truncated cone;
  • the first part has a cylindrical outer surface
  • the cylindrical inner cavity is cylindrical, or the cylindrical outer surface is cylindrical.
  • the connecting manner of the partial section of the expandable body and the cylindrical inner cavity is selected from welding, gluing, hot melt connection or tight fitting;
  • connection between the inner surface of the partial section of the expandable body and the cylindrical outer surface is selected from welding, gluing or hot melt connection;
  • connection between the second component and the shrinking section is selected from welding, gluing, hot melt connection or tight fitting.
  • the inflatable body is a mesh tube, a solid wall tube or an inflatable balloon;
  • the second component is a metal material or a polymer material
  • the second component is a heat shrinkable tube
  • the material of the second part is selected from polyolefin material, fluorinated ethylene propylene copolymer, neoprene or fluororubber.
  • the distance L between two adjacent shaping components satisfies the formula (1):
  • D is the outer diameter of the second part
  • the expandable body includes a first expandable body and a second expandable body, the first expandable body is sheathed in the second expandable body, and a partial section of the second expandable body is contained in the cylindrical lumen.
  • a method of manufacturing a bead string-like component comprising:
  • the second part is fixedly connected to the first part or the expandable body to obtain the beaded part.
  • the second component is a heat-shrinkable tube; the fixing connection of the second component to the first component or the expandable body includes:
  • the second part is heated to thermally connect the second part to the first part or the expandable body.
  • a stent delivery system comprising a delivery catheter, a delivery guide wire, and the beaded component according to any embodiment of the first aspect of the present disclosure
  • the distal end of the delivery guide wire is fixedly connected with the proximal end of the bead-shaped member
  • the beaded member is located within the delivery catheter and is in a compressed state.
  • the stent delivery system further comprises a stent positioned between the delivery catheter and the beaded member and in a compressed state;
  • the stent delivery system further comprises a delivery clip
  • the conveying clip includes a base and at least two clip wings; the at least two clip wings are respectively rotatably connected to the base; when the at least two clip wings are in the first position, they together form a prismatic shape.
  • a retracting portion the retracting portion has an inner space for retracting at least part of the stent; when the at least two clamping wings are rotated from the first position state to the second position state, they are separated from each other so that the retracting portion expands;
  • the base of the delivery clip is fixedly sleeved outside the proximal end of the bead string-shaped component; the clip wings of the delivery clip are in a first position, and at least part of the stent is folded inside.
  • a part of the tube section of the expandable body is bundled in a cylindrical inner cavity or the inner surface of the part of the tube section of the expandable body is fixedly connected with the cylindrical outer surface, A portion of the tubular section of the expandable body is contracted to form a beaded member.
  • the bead-shaped component is used to deliver the stent (that is, the stent is sleeved outside the bead-shaped component for delivery), on the one hand, the expansion of the bead-shaped component is conducive to the smooth release of the stent, so that the stent can be completely adhered to the diseased blood vessel.
  • the shaping assembly shrinks part of the tube segment of the inflatable body, the contact area between the inflatable body and the inner wall of other devices or the inner wall of the blood vessel is reduced, thereby reducing accidental damage to the intima of the blood vessel, and at the same time the inflatable body can be inflated.
  • the expansion section of the body can be deformed correspondingly according to the direction and shape of the blood vessel, which is beneficial to reduce the resistance of stent delivery and improve the smoothness of stent delivery.
  • the bead-string in the bead-string provided by the present disclosure, and the manufacturing method and application thereof, the bead-string can be formed on the basis of existing inflatable bodies (eg, mesh tubes, solid-wall tubes, and inflatable balloons), There is no need to change the existing manufacturing method of the expandable body, and the structure of the bead string is simple, easy to manufacture, and high reliability.
  • existing inflatable bodies eg, mesh tubes, solid-wall tubes, and inflatable balloons
  • FIG. 1 is a schematic structural diagram of a bead string component from a perspective according to a first embodiment of the present disclosure
  • FIG. 2 is a schematic structural diagram of the bead string component from another perspective according to the first embodiment of the present disclosure
  • FIG. 3 is a schematic view of the structure of a bead string component according to a second embodiment of the present disclosure
  • FIG. 4 is a schematic structural diagram of a bead string component according to a third embodiment of the present disclosure from a perspective;
  • FIG. 5 is a schematic structural diagram of a bead string component from a perspective according to a fourth embodiment of the present disclosure
  • FIG. 6 is a schematic structural diagram of a stent delivery system from a perspective according to a sixth embodiment of the present disclosure
  • FIG. 7 is a schematic structural diagram of a transport clip according to a sixth embodiment of the present disclosure from a viewing angle.
  • FIG. 1 is a schematic view of the structure of a bead string component according to a first embodiment of the present disclosure.
  • the beaded part is divided into a contraction section A and an expansion section B.
  • the number of the contraction section A and the expansion section B are both multiple and staggered.
  • the shape of the expansion section B is spindle-shaped, that is, the middle is thicker and the ends are thinner.
  • the beaded part comprises an expandable body 1 and a plurality of shape-setting assemblies 2a, 2b and 2c.
  • a plurality of shaping assemblies 2a, 2b and 2c are used to form a contraction section A, and an expansion section B is formed between two adjacent contraction sections A.
  • FIG. 2 is a schematic structural diagram of the bead string component from another perspective according to the first embodiment of the present disclosure.
  • each shaping assembly includes a first part 201 .
  • the first part 201 has a cylindrical interior in which a partial section of the inflatable body 1 is constricted.
  • the first part 201 Since the first part 201 is cut in FIG. 2 , the first part 201 is shown as upper and lower halves in FIG. 2 . It is easy to understand that, in an actual structure, the upper and lower halves of the first component 201 are integrated.
  • the outer shape of the first component 201 is a cylinder.
  • the shape of the first part 201 may also be a prism, a sphere, a truncated cone, or the like.
  • the inner cavity of the first component 201 is cylindrical. That is, the first member 201 is a circular tubular member as a whole. In other embodiments, the inner cavity of the first part 201 may also be prismatic or other shapes.
  • the material of the first component is a metal material or a polymer material.
  • the shaping assembly 2 further includes a second component 202 .
  • the second member 202 is a tubular member.
  • the constricted section of the beaded part is sleeved within the second part 202 .
  • the second part 202 Since the second part 202 is cut in FIG. 2 , it is shown as upper and lower halves in FIG. 2 . It is easy to understand that in the actual structure, the upper and lower halves of the second component 202 are integrated.
  • the material of the second component 202 is a polymer material. More specifically, the second part 202 is a heat shrinkable tube, which has the property of shrinking under heat. In other embodiments, the material of the second component 202 may also be a metal material.
  • the material of the second component is selected from polyolefin materials, fluorinated ethylene propylene copolymers, neoprene or fluororubber.
  • connection between the second part 202 and the first part 201 or the expandable body 1 is a heat fusion connection. That is, the second part 202 is a heat-shrinkable tube, which is sheathed outside the shrinking section and then heated so as to be connected with the first part 201 and the expandable body 1 .
  • the connection between the second component and the first component or the expandable body may also be welding, bonding, tight fitting, or the like.
  • the diameter of the cylindrical inner cavity of the first part 201 is smaller than the outer diameter of the expandable body 1 in the expanded state.
  • a partial section of the inflatable body 1 is collapsed in the cylindrical inner cavity of the first part 201 in a compressed state.
  • a partial section of the expandable body is constricted within the cylindrical lumen, causing the partial section of the expandable body to contract, thereby forming a beaded member.
  • the expansion of the bead-shaped component is conducive to the smooth release of the stent, so that the stent can be completely fitted to the diseased blood vessel; Therefore, the contact area between the inflatable body and the inner wall of other devices or the inner wall of the blood vessel is reduced, thereby reducing the accidental damage to the intima of the blood vessel. It is beneficial to reduce the resistance of stent delivery and improve the smoothness of stent delivery.
  • the second part 202 that is, a shape-setting assembly with a double-layer structure, the stability and reliability of the bead-string-shaped part are further improved.
  • the shaping assembly can form a bead string component on the basis of the existing expandable body, without changing the existing manufacturing method of the expandable body, and the bead string component has a simple structure, is easy to manufacture, and has high reliability.
  • the heat-melting connection method does not involve the production particles in the welding or bonding method, so as to avoid the production particles falling off into the blood vessels and causing danger to human health.
  • the risk of the component material entering the blood vessel can be further reduced.
  • both ends of the second component 202 have chamfered structures 202a.
  • the chamfered structure 202a can smoothly transition between the outer surface of the second part 202 and the outer surface of the expandable body 1 in the form of a slope.
  • the chamfered structure in the present disclosure may be any beveled structure capable of achieving a smooth transition, and the chamfering structure may be formed in other ways besides cutting.
  • the chamfered structure can be formed by injection molding.
  • the chamfered structure such as the chamfered structure 202a in FIG. 2 , can be formed by a thermoplastic method.
  • the three-part sections of the expandable body 1 are successively bundled in the cylindrical inner cavities of the first shaping member 2a, the second shaping member 2b and the third shaping member 2c.
  • the inner surfaces of the segments of the expandable body may be fixedly connected to the cylindrical outer surfaces of the shape-setting components.
  • the expandable body 1 is a mesh tube.
  • the inflatable body 1 may also be a solid wall tube or an inflatable balloon.
  • the size of each segment of the bead string balloon can be limited by controlling the distance between the shaping components, and the bead string structure can also be controlled by controlling the pressure value filled into the balloon. , to improve the conveying capacity of the conveying system in the axial direction.
  • the distance L between two adjacent shaping components satisfies the formula (1):
  • D is the outer diameter of the second component.
  • the distance L between the two shaping components is the distance between the opposite end surfaces of the two shaping components.
  • FIG. 3 is a schematic view of the structure of a bead string component according to a second embodiment of the present disclosure.
  • This embodiment differs from the first embodiment in that the first part 201 has a cylindrical outer surface and a subsection of the expandable body 1 is fixedly connected to this cylindrical outer surface. That is, the first member in the first embodiment is positioned outside the inflatable body, while the first member in this embodiment is positioned within the inflatable body.
  • the second part 202 is provided on the outer surface of the expandable body 1 .
  • the first part 201 has a cylindrical outer surface.
  • the first part 201 also has a cylindrical through inner cavity, that is, the first part 201 is a round tubular part as a whole.
  • the inner surface of the partial section of the expandable body 1 and the cylindrical outer surface of the first component 201 are fixedly connected by means of adhesive bonding.
  • the inner surface of a partial section of the expandable body 1 is coated with an adhesive and pressed to the cylindrical outer surface of the first part 201, so that the two are fixedly connected.
  • an adhesive is applied to the cylindrical outer surface of the first part 201, and the inner surface of a part of the expandable body 1 is pressed to the cylindrical outer surface of the first part 201, so that the two are fixedly connected .
  • the inner surface of the partial section of the expandable body 1 and the cylindrical outer surface of the first component 201 can also be fixedly connected by welding, heat fusion connection or the like.
  • both ends of the second component 202 are also provided with chamfered structures 202a.
  • the inner surface of the partial section of the inflatable body is fixedly connected to the cylindrical outer surface of the first part, so that the partial section of the inflatable body is contracted to form a beaded part, and the second part is in the
  • the outermost layer wraps the connection area of the first component and the expandable body. Therefore, the bead-string-shaped component in this embodiment can achieve technical effects similar to those of the first embodiment, which will not be repeated here.
  • the first part in this embodiment is disposed in the inflatable body, the first part in this embodiment can prevent the inflatable body from further shrinking at the engagement position with the first part, which avoids the use of tight fitting connection Due to the shrinkage of the expandable body, it is separated from the shape-setting component, which improves the stability of the structure.
  • FIG. 4 is a schematic view of the structure of the bead string component according to the third embodiment of the present disclosure.
  • the difference between this embodiment and the second embodiment is that the first part 201 in the second embodiment has a through cavity, while the first part 201 in this embodiment is a solid structure.
  • the first component in this embodiment adopts a solid structure, which is beneficial to reduce the manufacturing difficulty and improve the structural strength of the bead string component.
  • FIG. 5 is a schematic view of the structure of the bead string component according to the fourth embodiment of the present disclosure.
  • the difference between the bead string component in this embodiment and the bead string component in the first embodiment is that the bead string component in this embodiment includes two expandable bodies, namely a first expandable body 1a and a second expandable body body 1b.
  • the first inflatable body 1a is sheathed outside the second inflatable body 1b, and a partial section of the second inflatable body 1b is bundled in the cylindrical inner cavity of the first component 201 . In this way, it is beneficial to improve the anti-bending and kink performance of the bead string part.
  • a fifth embodiment of the present disclosure provides a method of manufacturing a bead string part, comprising the following steps:
  • the inflatable body is tightened. For example, stretching the expandable body causes it to contract.
  • At least two first components are sheathed outside the expandable body, or at least two first components are placed inside the expandable body.
  • cylindrical inner cavity or cylindrical outer surface of the first part is fixedly connected to the expandable body.
  • the two are fixedly connected by welding, gluing, hot melt connection or tight fitting.
  • the at least two second components are placed over the junction of the first component and the expandable body.
  • the second part is fixedly connected to the first part or the expandable body to obtain a beaded part.
  • the first part and the expandable body are respectively fixedly connected to the second part by means of a hot melt connection.
  • the second component is a heat shrink tube.
  • the step of fixedly attaching the second part to the first part or the expandable body includes heating the second part to thermally fuse the second part to the first part or the expandable body.
  • the stent delivery system includes a delivery catheter 4 , a delivery guide wire 3 , and a beaded member 6 .
  • the bead-shaped component 6 includes an expandable body 1 and a plurality of shaping components 2 .
  • the distal end (ie, the left end in FIG. 6 ) of the delivery guide wire 3 is fixedly connected with the proximal end (ie, the right end in FIG. 6 ) of the bead-string member 6 .
  • the beaded member 6 is located within the delivery catheter 4 and is in a compressed state.
  • the stent delivery system further includes a stent 5 .
  • the stent 5 is located between the delivery catheter 4 and the beaded member 6 and is in a compressed state.
  • the delivery catheter 4 can be sent into the human body and its distal opening is located near the target position, and then the delivery guide wire 3 is pushed to deliver the bead-shaped member 6 connected to it to the distal end, and through the bead
  • the string-shaped member 6 drives the bracket 5 to move together.
  • the expansion section of the bead-shaped member 6 moving out of the catheter will expand and expand in the radial direction, and drive the stent 5 sheathed outside it to expand, so that the stent 5 is released smoothly.
  • the stent delivery system further includes a delivery clip 8 .
  • FIG. 7 is a schematic structural diagram of a transport clip according to a sixth embodiment of the present disclosure from a viewing angle.
  • the conveying clip 8 includes a base 801 and at least two clip wings 802; the at least two clip wings 802 are respectively rotatably connected to the base 801; when the at least two clip wings 802 are in the first position, they form together
  • the retractable portion has a prismatic shape, and the retracted portion has an inner space for retracting at least part of the stent; when the at least two clip wings 802 are rotated from the first position to the second position, they are separated from each other to expand the retractable portion.
  • the base 801 of the delivery clip 8 is fixedly sleeved outside the proximal end of the bead string member 6 .
  • the first clip wing 802a and the second clip wing 802b of the conveying clip 8 are in the first position, and part of the bracket 5 is closed.
  • the conveying clip 8 in FIG. 6 is in the first position state
  • the conveying clip 8 in FIG. 7 is in the second position state.
  • the at least two clamping wings when they are in the first position, they together form a constricting portion with a prismatic shape, and the condensing portion has an inner space for condensing at least part of the bracket, and in the second position, they are separated from each other so that the condensing portion is closed.
  • Ministry expansion. On the one hand, the stent can be recovered when the stent release position is wrong or the release position needs to be adjusted. Difficult to operate and improve conveying efficiency.

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Abstract

珠串状部件及其制造方法和应用，珠串状部件包括可膨胀体（1）和至少两个定形组件（2a，2b，2c），每个定形组件（2a，2b，2c）包括第一部件（201）和第二部件（202）；第一部件（201）具有柱形内腔，可膨胀体（1）的部分区段被收束在柱形内腔中，以形成珠串状部件的收缩段（A）；或者第一部件（201）具有柱形外表面，可膨胀体（1）的部分区段的内表面固定连接至柱形外表面，以形成珠串状部件的收缩段（A）；第二部件（202）为管状部件，收缩段（A）套接在第二部件（202）内；相邻两个收缩段（A）之间形成珠串状部件的膨胀段（B）。珠串状部件有利于支架（5）顺利释放，有利于提高支架（5）输送的顺滑性，结构简单、易于制造、可靠性高。

Description

珠串状部件及其制造方法和应用 技术领域
本公开涉及介入治疗学领域，具体涉及珠串状部件及其制造方法和应用。
背景技术
血管支架(或简称为“支架”)可通过血管介入手术植入血管，用于治疗多种血管病症，例如治疗血管瘤的血流导向技术、治疗血管管腔狭窄或闭塞的血管重建技术。
在将血管支架送入血管时，会遇到一些问题。例如，在到达治疗部位后，处于压缩状态的支架由于受到扭转应力的影响而制约支架自膨胀。又例如，在支架输送过程中，输送系统通过性差，血管顺应性差，旋转同轴性差，使术者难以在介入手术中精确操控支架植入物在血管内的形态和位置。
上述输送系统对于支架植入物的较差控制性，降低了支架输送的效率，降低了支架到达病变部位的成功率延长了手术时间，使得手术失败和术后并发症风险居高不下。
因此，有必要提出一种新的进行支架输送的技术方案。
发明内容
本公开要解决的技术问题是：一方面，支架由于受到扭转应力的影响而无法自动释放；另一方面，支架输送过程中的操作较为费力和困难，降低了支架输送效率。
本公开提出了如下技术方案：
第一方面，提供了一种珠串状部件，包括可膨胀体和至少两个定形组件，每个所述定形组件包括第一部件和第二部件；
所述第一部件具有柱形内腔，所述可膨胀体的部分区段被收束在所述柱形内腔中，以形成所述珠串状部件的收缩段；或者所述第一部件具有柱形外表面，所述可膨胀体的部分区段的内表面固定连接至所述柱形外表面，以形成所述珠串状部件的收缩段；
所述第二部件为管状部件，所述收缩段套接在所述第二部件内；
相邻两个所述收缩段之间形成所述珠串状部件的膨胀段。
优选地，所述第二部件的端部设置有倒角结构；
优选地，所述第一部件具有柱形内腔，所述第一部件的外形选自圆柱体、棱柱体、球体或圆台；
优选地，所述第一部件具有柱形外表面；
优选地，所述柱形内腔为圆柱形，或者所述柱形外表面为圆柱形。
优选地，所述可膨胀体的部分区段与所述柱形内腔的连接方式选自焊接、粘接、热熔连接或紧配合；
优选地，所述可膨胀体的部分区段的内表面与所述柱形外表面之间的连接方式选自焊接、粘接或热熔连接；
优选地，所述第二部件与所述收缩段之间的连接方式选自焊接、粘接、热熔连接或紧配合。
优选地，所述可膨胀体为网状管、实壁管或者膨胀式球囊；
优选地，所述第二部件为金属材料或高分子材料；
优选地，所述第二部件为热缩管；
优选地，所述第二部件的材料选自聚烯烃材料、氟化乙烯丙烯共聚物、氯丁橡胶或氟 橡胶。
优选地，相邻两个所述定形组件之间的距离L满足式(1)：
L＞D                   (1)
其中，D为所述第二部件的外径；
优选地，所述可膨胀体包括第一可膨胀体和第二可膨胀体，所述第一可膨胀体套设在所述第二可膨胀体内，所述第二可膨胀体的部分区段被收束在所述柱形内腔中。
第二方面，提供了一种制造如本公开第一方面任一实施方式所述的珠串状部件的方法，包括：
使所述可膨胀体收缩；
将至少两个所述第一部件套在所述可膨胀体外，或者将至少两个所述第一部件置于所述可膨胀体内；
将所述第一部件的柱形内腔或柱形外表面与所述可膨胀体固定连接；
将至少两个所述第二部件套在所述第一部件与所述可膨胀体的连接处之外；
将所述第二部件与所述第一部件或所述可膨胀体固定连接，得到所述珠串状部件。
优选地，所述第二部件为热缩管；所述将所述第二部件与所述第一部件或所述可膨胀体固定连接，包括：
对所述第二部件进行加热，以使所述第二部件与所述第一部件或所述可膨胀体热熔连接。
第三方面，提供了一种支架输送系统，包括输送导管、输送导丝和如本公开第一方面任一实施方式所述的珠串状部件；
所述输送导丝的远端与所述珠串状部件的近端固定连接；
所述珠串状部件位于所述输送导管内并处于压缩状态。
优选地，所述支架输送系统还包括支架，所述支架位于所述输送导管和所述珠串状部件之间并处于压缩状态；
优选地，所述支架输送系统还包括输送夹；
所述输送夹包括基座和至少两个夹翼；所述至少两个夹翼分别与所述基座转动连接；所述至少两个夹翼处于第一位置状态时，共同形成具有棱柱外形的收拢部，所述收拢部具有用于收拢至少部分支架的内部空间；所述至少两个夹翼由所述第一位置状态转动至第二位置状态时，相互分离使得所述收拢部扩张；
所述输送夹的所述基座固定套接在所述珠串状部件的近端外；所述输送夹的所述夹翼处于第一位置状态，并将至少部分所述支架收拢在内。
本发明的有益效果包括：
在本公开提供的珠串状部件及其制造方法和应用中，可膨胀体的部分管段被收束在柱形内腔中或者可膨胀体的部分管段的内表面与柱形外表面固定连接，使得可膨胀体的部分管段收缩，从而形成珠串状部件。在利用该珠串状部件输送支架(即，将支架套接于该珠串状部件外进行输送)时，一方面，珠串状部件的膨胀有利于支架顺利释放，使支架与病变血管完全贴合；另一方面，由于定形组件使可膨胀体的部分管段收缩，因此减小了可膨胀体与其他器械内壁或者血管内壁的接触面积，进而降低了意外的对于血管内膜损伤，同时可膨胀体的膨胀段，根据血管走向和形状可进行相应的形变，有利于降低支架输送的阻力、提高支架输送的顺滑性。
此外，在本公开提供的珠串状部件及其制造方法和应用中，可以在现有可膨胀体(例 如网状管、实壁管和膨胀式球囊)的基础上形成珠串状部件，无需改变现有的可膨胀体的制造方法，并且使珠串状部件结构简单、易于制造、可靠性高。
附图说明
为了更清楚地说明本公开实施例的技术方案，下面将对本公开实施例描述中所需要使用的附图作简单的介绍；此处所说明的附图用来提供对本公开的进一步理解，构成本公开的一部分，本公开的示意性实施例及其说明用于解释本公开，并不构成对本公开的不当限定。
图1是根据本公开第一实施例的珠串状部件的一种视角的结构示意图；
图2是根据本公开第一实施例的珠串状部件的另一种视角的结构示意图；
图3是根据本公开第二实施例的珠串状部件的一种视角的结构示意图；
图4是根据本公开第三实施例的珠串状部件的一种视角的结构示意图；
图5是根据本公开第四实施例的珠串状部件的一种视角的结构示意图；
图6是根据本公开第六实施例的支架输送系统的一种视角的结构示意图；
图7是根据本公开第六实施例的输送夹的一种视角的结构示意图。
附图标记说明：1-可膨胀体；1a-第一可膨胀体；1b-第二可膨胀体；2-定形组件；201-第一部件；202-第二部件；202a-倒角结构；2a-第一定形组件；2b-第二定形组件；2c-第三定形组件；3-输送导丝；4-输送导管；5-支架；6-珠串状部件；8-输送夹；801-基座；802-夹翼；802a-第一夹翼；802b-第二夹翼。
具体实施方式
下面结合附图和实施例对本公开作进一步的详细说明。可以理解的是，此处所描述的具体实施例仅仅用于解释相关发明，而非对该发明的限定。另外还需要说明的是，为了便于描述，附图中仅示出了与有关发明相关的部分。
在本发明的描述中，需要说明的是，术语“上”、“下”、“内”、“外”等指示的方位或位置关系，仅是为了便于描述本发明和简化描述，而不是指示或暗示所指的装置或元件必须具有特定的方位、以特定的方位构造和操作，因此不能理解为对本发明的限制。此外，术语“第一”、“第二”、“第三”仅用于描述目的，而不能理解为指示或暗示相对重要性。
在本发明的描述中，需要说明的是，除非另有明确的规定和限定，术语“安装”、“相连”、“连接”等应做广义理解，例如，可以是固定连接，也可以是可拆卸连接，或一体地连接；可以是机械连接，也可以是电连接；可以是直接相连，也可以通过中间媒介间接相连。对于本领域的普通技术人员而言，可以根据具体情况理解上述术语在本发明中的具体含义。
在本发明的描述中，需要说明的是，在不冲突的情况下，本公开中的实施例及实施例中的特征可以相互组合。
图1是根据本公开第一实施例的珠串状部件的一种视角的结构示意图。如图1所示，该珠串状部件分为收缩段A和膨胀段B。收缩段A和膨胀段B的数目均为多个并且交错排布。其中，膨胀段B的外形呈纺锤状，即中间较粗两端较细。
如图1所示，珠串状部件包括可膨胀体1和多个定形组件2a、2b和2c。其中，多个定形组件2a、2b和2c用于形成收缩段A，相邻两个收缩段A之间形成膨胀段B。
图2是根据本公开第一实施例的珠串状部件的另一种视角的结构示意图。如图2所示，每个定形组件包括第一部件201。第一部件201具有柱形内腔，可膨胀体1的部分区段被收束在柱形内腔中。
由于图2中对第一部件201进行了剖切，因此第一部件201在图2中体现为上下两半部分。容易理解，在实际结构中，第一部件201的上下两半部分为一整体。
在本实施例中，第一部件201的外形为圆柱体。在其他实施例中，第一部件201的外形还可以是棱柱体、球体或者圆台等。
在本实施例中，第一部件201的内腔为圆柱形。即，第一部件201整体上为圆管状部件。在其他实施例中，第一部件201的内腔也可以是棱柱形或者其他形状。
在本实施例中，第一部件的材料为金属材料或者高分子材料。
在本实施例中，定形组件2还包括第二部件202。第二部件202为管状部件。珠串状部件的收缩段套接在第二部件202内。
由于图2中对第二部件202进行了剖切，因此其在图2中体现为上下两半部分。容易理解，在实际结构中，第二部件202的上下两半部分为一整体。
在本实施例中，第二部件202的材料为高分子材料。更具体地，第二部件202为热缩管，具有受热收缩的特性。在其他实施例中，第二部件202的材料也可以是金属材料。
在一个例子中，第二部件的材料选自聚烯烃材料、氟化乙烯丙烯共聚物、氯丁橡胶或氟橡胶。
在本实施例中，第二部件202与第一部件201或者可膨胀体1之间的连接方式为热熔连接。即，第二部件202为热缩管，将其套接在收缩段外后进行加热，使其与第一部件201和可膨胀体1连接。在其他实施例中，第二部件与第一部件或者可膨胀体之间的连接方式还可以是焊接、粘接和紧配合等。
在本实施例中，第一部件201的柱形内腔的直径小于可膨胀体1在膨胀状态下的外径。因此，可膨胀体1的部分区段以压缩状态收束在第一部件201的柱形内腔中。
在本实施例中，可膨胀体的部分区段被收束在柱形内腔中，使得可膨胀体的部分区段 收缩，从而形成珠串状部件。在利用该珠串状部件输送支架时，一方面，珠串状部件的膨胀有利于支架顺利释放，使支架与病变血管完全贴合；另一方面，由于定形组件使可膨胀体的部分区段收缩，因此减小了可膨胀体与其他器械内壁或者血管内壁的接触面积，进而降低了意外的对于血管内膜损伤，同时可膨胀体的膨胀段，根据血管走向和形状可进行相应的形变，有利于降低支架输送的阻力、提高支架输送的顺滑性。通过设置第二部件202，即采用双层结构的定形组件，有利于进一步珠串状部件的稳固性和可靠性。
此外，利用上述定形组件可以在现有可膨胀体的基础上形成珠串状部件，无需改变现有的可膨胀体的制造方法，并且使珠串状部件结构简单、易于制造、可靠性高。
在第二部件采用热缩管的实施方式中，热熔连接方式不涉及焊接或粘接方式中的生产微粒，从而避免生产微粒脱落至血管内给人体健康带来危险。此外，由于第二部件在最外层的包裹，能够进一步降低部件材料进入血管的风险。
在本实施例中，第二部件202的两端均具有倒角结构202a。倒角结构202a可使第二部件202的外表面和可膨胀体1的外表面之间以斜面形式平滑过渡。需要说明的是，本公开中的倒角结构可以是任何能够实现平滑过渡的斜角结构，其形成除了采用切削方式外，还可以采用其他方式。例如，可以通过注塑方式形成倒角结构。又例如，可以通过热塑方式形成倒角结构，该倒角结构例如是图2中的倒角结构202a。
通过在第二部件的端部设置倒角结构，有利于进一步降低支架输送过程中的阻力。
在本实施例中，可膨胀体1的三部分区段依次被收束在第一定形组件2a、第二定形组件2b和第三定形组件2c的柱形内腔中。在其他实施例中，可膨胀体的多个区段的内表面可以固定连接至多个定形组件的柱形外表面。
在本实施例中，可膨胀体1为网状管。在其他实施例中，可膨胀体1还可以是实壁管或者膨胀式球囊。在可膨胀体为膨胀式球囊的情况下，可以通过控制定形组件之间的距离， 限制珠串球囊各段膨胀的大小，还可以通过控制充入球囊的压力值，结合珠串结构，提高输送系统在轴向方向上的输送能力。
在本实施例中，相邻两个定形组件之间的距离L满足式(1)：
L＞D               (1)
其中，D为所述第二部件的外径。其中，如图1所示，两个定形组件之间的距离L为两个定形组件的相对端面之间的距离。通过将相邻两个定形组件之间的距离L设计为满足式(1)，可以保证膨胀段的直径大于收缩段的直径，从而形成珠串状结构。
图3是根据本公开第二实施例的珠串状部件的一种视角的结构示意图。该实施例与第一实施例的区别在于，第一部件201具有柱形外表面并且可膨胀体1的部分区段与该柱形外表面固定连接。即，第一实施例中的第一部件设置在可膨胀体外，而本实施例中的第一部件设置在可膨胀体内。此外，本实施例中第二部件202设置在可膨胀体1的外表面。
在本实施例中，第一部件201具有圆柱形外表面。此外，与第一实施例类似，第一部件201还具有圆柱形的贯通内腔，即第一部件201整体上为圆管状部件。
在本实施例中，可膨胀体1的部分区段的内表面与第一部件201的柱形外表面之间通过粘接方式固定连接。例如，可膨胀体1的部分区段的内表面涂布粘接剂，并将其压合至第一部件201的柱形外表面，从而使二者固定连接。或者，在第一部件201的柱形外表面涂布粘接剂，并将可膨胀体1的部分区段的内表面压合至第一部件201的柱形外表面，从而使二者固定连接。在其他实施例中，可膨胀体1的部分区段的内表面与第一部件201的柱形外表面之间还可以通过焊接、热熔连接等方式固定连接。
在本实施例中，第二部件202的两端同样设置有倒角结构202a。
在本实施例中，可膨胀体的部分区段的内表面与第一部件的柱形外表面固定连接，使 得可膨胀体的部分区段收缩，从而形成珠串状部件，并且第二部件在最外层包裹第一部件和可膨胀体的连接区域。因此，本实施例中的珠串状部件能够实现与第一实施例类似的技术效果，这里不再赘述。
此外，由于本实施例中的第一部件设置在可膨胀体内，因此本实施例中的第一部件能够阻止可膨胀体在与第一部件的接合位置进一步收缩，避免了在采用紧配合连接时因可膨胀体收缩引起其与定形组件脱离，提高了结构的稳定性。
图4是根据本公开第三实施例的珠串状部件的一种视角的结构示意图。本实施例与第二实施例的区别在于，第二实施例中的第一部件201具有贯通的内腔，而本实施例中的第一部件201为实心结构。
本实施例中的第一部件采用实心结构，有利于降低其制造难度并提高珠串状部件的结构强度。
图5是根据本公开第四实施例的珠串状部件的一种视角的结构示意图。本实施例中珠串状部件与第一实施例中珠串状部件的区别在于，本实施例中的珠串状部件包括两个可膨胀体，即第一可膨胀体1a和第二可膨胀体1b。
在本实施例中，第一可膨胀体1a套设在第二可膨胀体1b外，第二可膨胀体1b的部分区段被收束在第一部件201的柱形内腔中。如此，有利于提高珠串状部件的抗弯曲、扭结性能。
本公开第五实施例提供一种制造珠串状部件的方法，包括以下步骤：
首先，使可膨胀体收紧。例如，拉伸可膨胀体使其收紧。
其次，将至少两个第一部件套在可膨胀体外，或者将至少两个第一部件置于可膨胀体内。
再次，将第一部件的柱形内腔或柱形外表面与可膨胀体固定连接。例如，通过焊接、粘接、热熔连接或紧配合方式使二者固定连接。
之后，将至少两个第二部件套在第一部件与可膨胀体的连接处之外。
最后，将第二部件与第一部件或可膨胀体固定连接，得到珠串状部件。例如，通过热熔连接使第一部件和可膨胀体分别与第二部件固定连接。
在一些可选的实施方式中，第二部件为热缩管。将第二部件与第一部件或可膨胀体固定连接的步骤包括：对第二部件进行加热，以使第二部件与第一部件或可膨胀体热熔连接。
图6是根据本公开第六实施例的支架输送系统的一种视角的结构示意图。如图6所示，该支架输送系统包括输送导管4、输送导丝3、和珠串状部件6。其中，珠串状部件6包括可膨胀体1和多个定形组件2。
在本实施例中，输送导丝3的远端(即图6中的左端)与珠串状部件6的近端(即图6中的右端)固定连接。珠串状部件6位于输送导管4内并处于压缩状态。
在一些可选的实施方式中，支架输送系统还包括支架5。支架5位于输送导管4和珠串状部件6之间并处于压缩状态。
在支架输送过程中，可以先将输送导管4送入人体内并使其远端开口位于目标位置附近，再推动输送导丝3将与其相连的珠串状部件6向远端输送，并通过珠串状部件6带动支架5共同运动。
在支架5到达输送导管4的远端开口处后，继续推动输送导丝3可将珠串状部件6和支架2逐渐移出输送导管4。由于可膨胀体1具有自膨胀的特性，珠串状部件6移出导管的膨胀段会沿径向膨胀展开，并带动套接在其外部的支架5展开，使得支架5顺利释放。
在一些可选的实施方式中，支架输送系统还包括输送夹8。
图7是根据本公开第六实施例的输送夹的一种视角的结构示意图。如图7所示，输送夹8包括基座801和至少两个夹翼802；至少两个夹翼802分别与基座801转动连接；至少两个夹翼802处于第一位置状态时，共同形成具有棱柱外形的收拢部，收拢部具有用于收拢至少部分支架的内部空间；至少两个夹翼802由第一位置状态转动至第二位置状态时，相互分离使得收拢部扩张。
如图6所示，输送夹8的基座801固定套接在珠串状部件6的近端外。输送夹8的第一夹翼802a和第二夹翼802b处于第一位置状态，并将支架5的部分区段收拢在内。在本实施例中，图6中的输送夹8处于第一位置状态，图7中的输送夹8处于第二位置状态。
在本实施例中，至少两个夹翼处于第一位置状态时，共同形成具有棱柱外形的收拢部，收拢部具有用于收拢至少部分支架的内部空间，在第二位置状态时相互分离使得收拢部扩张。一方面能够在支架释放位置错误或者释放位置需要调整等情况下对支架进行回收，另一方面使得支架输送部件与输送导管内壁保持线接触，降低了接触面积从而减小了摩擦阻力，有利于降低操作难度并提高输送效率。
以上描述仅为本公开的较佳实施例以及对所运用技术原理的说明。本领域技术人员应当理解，本公开中所涉及的发明范围，并不限于上述技术特征的特定组合而成的技术方案，同时也应涵盖在不脱离上述发明构思的情况下，由上述技术特征或其等同特征进行任意组合而形成的其它技术方案。例如上述特征与本公开中公开的(但不限于)具有类似功能的技术特征进行互相替换而形成的技术方案。

Claims (10)

  1. 一种珠串状部件，其特征在于，包括可膨胀体和至少两个定形组件，每个所述定形组件包括第一部件和第二部件；
    所述第一部件具有柱形内腔，所述可膨胀体的部分区段被收束在所述柱形内腔中，以形成所述珠串状部件的收缩段；或者所述第一部件具有柱形外表面，所述可膨胀体的部分区段的内表面固定连接至所述柱形外表面，以形成所述珠串状部件的收缩段；
    所述第二部件为管状部件，所述收缩段套接在所述第二部件内；
    相邻两个所述收缩段之间形成所述珠串状部件的膨胀段。
  2. 根据权利要求1所述的珠串状部件，其中，所述第二部件的端部设置有倒角结构；
    优选地，所述第一部件具有柱形内腔，所述第一部件的外形选自圆柱体、棱柱体、球体或圆台；
    优选地，所述第一部件具有柱形外表面；
    优选地，所述柱形内腔为圆柱形，或者所述柱形外表面为圆柱形。
  3. 根据权利要求1或2所述的珠串状部件，其中，所述可膨胀体的部分区段与所述柱形内腔的连接方式选自焊接、粘接、热熔连接或紧配合；
    优选地，所述可膨胀体的部分区段的内表面与所述柱形外表面之间的连接方式选自焊接、粘接或热熔连接；
    优选地，所述第二部件与所述收缩段之间的连接方式选自焊接、粘接、热熔连接或紧配合。
  4. 根据权利要求1-3中任一项所述的珠串状部件，其中，所述可膨胀体为网状管、实壁管或者膨胀式球囊；
    优选地，所述第二部件为金属材料或高分子材料；
    优选地，所述第二部件为热缩管；
    优选地，所述第二部件的材料选自聚烯烃材料、氟化乙烯丙烯共聚物、氯丁橡胶或氟橡胶。
  5. 根据权利要求1-4中任一项所述的珠串状部件，其中，相邻两个所述定形组件 之间的距离L满足式(1)：
    L＞D   (1)
    其中，D为所述第二部件的外径；
  6. 根据权利要求1-5中任一项所述的珠串状部件，其中，所述可膨胀体包括第一可膨胀体和第二可膨胀体，所述第一可膨胀体套设在所述第二可膨胀体内，所述第二可膨胀体的部分区段被收束在所述柱形内腔中。
  7. 一种制造如权利要求1-6中任一项所述的珠串状部件的方法，其特征在于，包括：
    使所述可膨胀体收缩；
    将至少两个所述第一部件套在所述可膨胀体外，或者将至少两个所述第一部件置于所述可膨胀体内；
    将所述第一部件的柱形内腔或柱形外表面与所述可膨胀体固定连接；
    将至少两个所述第二部件套在所述第一部件与所述可膨胀体的连接处之外；
    将所述第二部件与所述第一部件或所述可膨胀体固定连接，得到所述珠串状部件。
  8. 根据权利要求7所述的方法，其中，所述第二部件为热缩管；所述将所述第二部件与所述第一部件或所述可膨胀体固定连接，包括：
    对所述第二部件进行加热，以使所述第二部件与所述第一部件或所述可膨胀体热熔连接。
  9. 一种支架输送系统，其特征在于，包括输送导管、输送导丝和如权利要求1-6中任一项所述的珠串状部件；
    所述输送导丝的远端与所述珠串状部件的近端固定连接；
    所述珠串状部件位于所述输送导管内并处于压缩状态。
  10. 根据权利要求9所述的支架输送系统，其中，所述支架输送系统还包括支架，所述支架位于所述输送导管和所述珠串状部件之间并处于压缩状态；
    优选地，所述支架输送系统还包括输送夹；
    所述输送夹包括基座和至少两个夹翼；所述至少两个夹翼分别与所述基座转动连 接；所述至少两个夹翼处于第一位置状态时，共同形成具有棱柱外形的收拢部，所述收拢部具有用于收拢至少部分支架的内部空间；所述至少两个夹翼由所述第一位置状态转动至第二位置状态时，相互分离使得所述收拢部扩张；
    所述输送夹的所述基座固定套接在所述珠串状部件的近端外；所述输送夹的所述夹翼处于第一位置状态，并将至少部分所述支架收拢在内。
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