WO2024138024A3 - Identification de modèle avec des données d'entrée incomplètes de diabète de type i - Google Patents

Identification de modèle avec des données d'entrée incomplètes de diabète de type i Download PDF

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Publication number
WO2024138024A3
WO2024138024A3 PCT/US2023/085495 US2023085495W WO2024138024A3 WO 2024138024 A3 WO2024138024 A3 WO 2024138024A3 US 2023085495 W US2023085495 W US 2023085495W WO 2024138024 A3 WO2024138024 A3 WO 2024138024A3
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WO
WIPO (PCT)
Prior art keywords
correction value
parameters
time
glucose
dynamics model
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2023/085495
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English (en)
Other versions
WO2024138024A2 (fr
Inventor
Basak OZASLAN
Eleonora Maria AIELLO
III Francis J. Doyle
Eyal Dassau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Harvard University
Original Assignee
Harvard University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard University filed Critical Harvard University
Publication of WO2024138024A2 publication Critical patent/WO2024138024A2/fr
Publication of WO2024138024A3 publication Critical patent/WO2024138024A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/63—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/20—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G16H20/17—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/67—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/70—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Primary Health Care (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Data Mining & Analysis (AREA)
  • Business, Economics & Management (AREA)
  • Pathology (AREA)
  • Databases & Information Systems (AREA)
  • General Business, Economics & Management (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

L'invention concerne un système et un procédé pour identifier un modèle de dynamique de glucose personnalisé pour gérer le glucose d'un patient. Le procédé consiste à collecter des données de sortie de concentration de glucose du patient pendant une période. Les données d'entrée de taille des glucides et de perfusion d'insuline sont collectées à partir du patient pendant la période. Des paramètres d'un modèle de dynamique de glucose sont optimisés par résolution d'un problème d'optimisation itératif tel qu'un problème des moindres carrés non linéaire sur la base des données collectées parallèlement à l'établissement d'un temps et d'une quantité constants d'une valeur de correction. Le temps et la quantité d'une valeur de correction modifiée sont déterminés sur la base de l'exécution d'un programme quadratique entier mixte sur les données collectées parallèlement à l'établissement d'une valeur constante pour les paramètres du modèle de dynamique de glucose. Une valeur de correction finale et des paramètres optimisés finaux du modèle sont fournis sur la base de l'itération des paramètres d'optimisation et de la détermination de la valeur de correction modifiée.
PCT/US2023/085495 2022-12-22 2023-12-21 Identification de modèle avec des données d'entrée incomplètes de diabète de type i Ceased WO2024138024A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202263434833P 2022-12-22 2022-12-22
US63/434,833 2022-12-22

Publications (2)

Publication Number Publication Date
WO2024138024A2 WO2024138024A2 (fr) 2024-06-27
WO2024138024A3 true WO2024138024A3 (fr) 2024-07-25

Family

ID=91590129

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2023/085495 Ceased WO2024138024A2 (fr) 2022-12-22 2023-12-21 Identification de modèle avec des données d'entrée incomplètes de diabète de type i

Country Status (1)

Country Link
WO (1) WO2024138024A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN120044213B (zh) * 2025-04-24 2025-10-03 内蒙古黄河工贸集团千里山煤焦化有限责任公司 基于小焦炉的炼焦指标监测分析方法、系统、设备和介质

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140039823A1 (en) * 2010-11-12 2014-02-06 Nextnav, Llc Wide area positioning system
WO2015021441A1 (fr) * 2013-08-09 2015-02-12 Alere San Diego, Inc. Dosage et méthode de détermination d'insuline active
US20210369149A1 (en) * 2011-04-15 2021-12-02 Dexcom, Inc. Advanced analyte sensor calibration and error detection

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140039823A1 (en) * 2010-11-12 2014-02-06 Nextnav, Llc Wide area positioning system
US20210369149A1 (en) * 2011-04-15 2021-12-02 Dexcom, Inc. Advanced analyte sensor calibration and error detection
WO2015021441A1 (fr) * 2013-08-09 2015-02-12 Alere San Diego, Inc. Dosage et méthode de détermination d'insuline active

Also Published As

Publication number Publication date
WO2024138024A2 (fr) 2024-06-27

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