WO2024252040A1 - Complejo nutricional capilar - Google Patents

Complejo nutricional capilar Download PDF

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Publication number
WO2024252040A1
WO2024252040A1 PCT/ES2024/070302 ES2024070302W WO2024252040A1 WO 2024252040 A1 WO2024252040 A1 WO 2024252040A1 ES 2024070302 W ES2024070302 W ES 2024070302W WO 2024252040 A1 WO2024252040 A1 WO 2024252040A1
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Prior art keywords
hair
zinc
capillary
molybdenum
nutritional
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PCT/ES2024/070302
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English (en)
French (fr)
Inventor
Antero FERNÁNDEZ SÁNCHEZ
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Natural Folic SL
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Natural Folic SL
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16—Inorganic salts, minerals or trace elements
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/175—Amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
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    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A61K31/51—Thiamines, e.g. vitamin B1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135—Compounds containing heavy metals
    • A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/34—Copper; Compounds thereof
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/77—Sapindaceae (Soapberry family), e.g. lychee or soapberry
    • A—HUMAN NECESSITIES
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]

Definitions

  • the present invention relates to a hair nutritional complex whose obvious purpose is to combat poor hair nutrition.
  • the object of the invention is to provide a product based on the study of hair needs for its correct nutrition, and adapting the correlations between its various components so that its effectiveness is complete.
  • This compound has a specific characteristic which is that its entire formulation is a combination of natural products, without any type of drug.
  • the object of the invention is to provide a product that allows the stimulation of the follicular unit in humans using natural resources so that it can be used in seasonal or continuous effluvia in all types of people or in patients who do not wish to be treated with drugs, oncological, pre-menopausal and post-menopausal, operated on for morbid obesity, post-partum, stress and all types of diffuse and androgenic alopecia without the use of any type of drug.
  • the product stimulates the follicular unit at a central level from the medulla with its own nutritional needs to the promontory for correct formation of the external root epithelium.
  • Drugs have also been used for another specialty in which a slight improvement in hair has been observed but without a lasting clinical resolution.
  • the recommended nutritional hair complex fully satisfactorily resolves the problems described above, all based on a composition based on natural products, without any type of drug.
  • the product of the invention is made up of the following components:
  • Hair is made up of a fibrous protein: alpha keratin. These keratins also have a special structure with intermediate filaments. These are aligned in such a way that they create the hair fiber.
  • a characteristic feature of alpha keratin is its high sulfur content. This is due to the high content of the diamino acid cystine.
  • cysteine and methionine are the only naturally occurring amino acids that contain sulfur. The sulfur bonds can form disulfide bridges, whereby the two cysteine molecules ultimately form the diamino acid cystine.
  • antioxidant power is 800 times more powerful than coenzyme Q10 and 6000 times more powerful than vitamin C. It is an antioxidant explosion for all cells.
  • Melatonin the hormone universally known for its power to regulate circadian rhythms, is also involved in hair growth. Until now, popularly, it was linked to its ability to facilitate sleep, but science has been working on it for some time. researching its relationship with hair. And there is good news, since according to the study Melatonin and hair physiology by Dr. Massimo Milani, its antioxidant and anti-inflammatory activities on the skin have been demonstrated, as well as its involvement in hair growth by promoting its anagen phase and attenuating oxidative stress in the hair follicle.
  • Biotin improves the infrastructure of keratin, a basic protein that makes up hair, skin and nails, so it can improve hair health, including volume and coverage of the scalp.
  • Vitamin A and its derivatives are important for the development and maintenance of multiple epithelial tissues, including skin, hair and sebaceous glands, as serious adverse effects are observed in vitamin A deficiency or excess.
  • flavonoid compounds are known to act as a powerful antioxidant that can protect against cell damage. Furthermore, its anti-inflammatory, astringent and tonic properties are effective for the skin. That is why there are so many products with formulas to firm, tone the skin and help reduce expression lines. For example: body creams, lotions, cleansing and moisturizing tonics.
  • This plant also contributes to strengthening the scalp by improving capillary blood flow, promoting hair growth and reducing hair loss.
  • hemoglobin which are the proteins that transport oxygen to the rest of the body.
  • One of its benefits is that it allows oxygen to be transported to the hair roots, thus influencing healthier and stronger hair.
  • Selenium an anti-infective agent, relieves itching and flaking of the scalp and removes dry, flaky particles commonly called dandruff or seborrhea.
  • Collagen is a key ingredient for healthy, strong hair. This substance, which the body produces naturally, tends to disappear with age, making hair look dull, weak and brittle.
  • the main advantage of taking collagen is that it acts by regenerating the hair in depth.
  • Zinc deficiency is actually the main cause of the deterioration of the protein structure that makes up the hair follicle. This weakening of the follicle can in turn cause hair deterioration and hair alopecia.
  • Zinc has also been shown to play a crucial role in the production of DNA and RNA, being necessary for the division of hair follicle cells and for healthy hair growth. healthier hair.
  • Molybdenum is responsible for the metabolism of sulfurous amino acids, particularly methionine, essential for keratin synthesis.
  • Molybdenum is a mineral we need to stay healthy.
  • the body uses molybdenum to process proteins and genetic material such as DNA. Molybdenum also helps break down medications and toxic substances that enter the body.
  • composition by weight More specifically, these elements will participate in the following composition by weight:
  • these may contain plant or animal material on the outside, as well as glycerin for coating.
  • the compound can be manufactured in liquid form or in tablets, pills, hard or soft capsules, determining a compound for stimulation of the follicular unit in humans using natural resources.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Inorganic Chemistry (AREA)
  • Botany (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
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  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Complejo nutritional capilar que presenta la siguiente composición: Serenoa repens entre 100 y 200 mg, Pygeum africanum entre 50 y 100 mg, cistina entre 200 y 300 mg, metionina entre 50 y 125 mg, astaxantina entre 4 y 8 mg, melatonina entre 0,2 y 1 mg, castaño de Indias entre 10 y 50 mg, hierro entre 6 y 14 mg, colágeno entre 10 y 40 mg, zinc entre 5 y 10 mg, biotina entre 5 y 50 ng, retinol entre 300 y 800 ng, molibdeno entre 5 y 25 ng y selenio entre 10 y 55 ng.

Description

D E S C R I P C I Ó N
Complejo nutricional capilar
SECTOR DE LA TÉCNICA
La presente invención se refiere a un complejo nutricional capilar cuya evidente finalidad es la de combatir la mala nutrición capilar.
Es objeto de la invención proporcionar un producto basado en el estudio de las necesidades capilares para su correcta nutrición, y adaptando las correlaciones entre sus diversos componentes para que su eficacia sea completa.
Este compuesto posee una característica específica que es que toda su formulación es de combinación de productos naturales, sin ningún tipo de fármaco.
De forma más concreta, el objeto de la invención es proporcionar un producto que permita la estimulación de la unidad folicular en humanos mediante recursos naturales para poder utilizarlo en efluvios estacionales o de forma continua en todo tipo de personas o en pacientes que no deseen ser tratados por fármacos, oncológicos, pre-menopausia y post-menopausia, operados de obesidad mórbida, post-parto, stress y todo tipo de alopecias difusas y androgénicas sin la utilización de ningún tipo de fármaco.
El producto estimula la unidad folicular a nivel central desde la médula con sus propias necesidades alimenticias al promontorio para una correcta formación del epitelio radicular externo.
ANTECEDENTES DE LA INVENCIÓN
El mantenimiento del cabello humano ha estado en el centro de interés humano desde la antigüedad, siempre se ha optado por tratamientos capilares de diversa índole con el objeto de embellecerlo y/o mantenerlo, de manera que la lucha contra las alopecias nunca ha tenido fin.
Este tipo de tratamientos se aplican desde el exterior (donde no se encuentra la unidad folicular) con resultados deficientes en la mayoría de los casos.
También se han utilizado fármacos para otra especialidad en la que se ha observado una ligera mejoría en el cabello pero sin una resolución clínica perdurable.
Hasta ahora no existía un tratamiento verdaderamente eficaz y específico contra la caída del cabello.
EXPLICACIÓN DE LA INVENCIÓN
El complejo nutricional capilar que se preconiza resuelve de forma plenamente satisfactoria la problemática anteriormente expuesta, todo ello en base a una composición a base de productos naturales, sin ningún tipo de fármaco.
Para ello, y de forma más concreta, el producto de la invención está constituido a partir de los siguientes componentes:
Sabal (saw palmetto):
Frena la alopecia. Combate la caída del cabello, pues ayuda al crecimiento y al aumento de volumen. Esto se consigue gracias a la regulación hormonal y a la normalización de los niveles de DHT.
Pygeum afrícanunr.
Su mecanismo de acción es muy similar al Saw palmetto. Tanto la alopecia androgenética como la hiperplasia benigna de próstata comparten una misma causa: un exceso de dihidrotestosterona. Sus principales principios activos, el beta sitosterol y el n-docosanol, actúan inhibiendo la enzima 5 alfa reductasa de forma eficaz. De esta manera, evitan la conversión de testosterona en DHT, que es la causante de la caída del cabello en la alopecia androgénica.
Cistina:
Para comprender mejor su campo de acción, debemos introducirnos en el interior de la fibra capilar. El cabello está compuesto por una proteína fibrosa: la queratina alfa. Estas queratinas, así mismo, cuentan con una estructura especial con filamentos intermedios. Estos se encuentran alineados de tal forma que crean la fibra capilar.
Un rasgo característico de la queratina alfa es su alto valor en azufre. Este encuentra su origen en el alto contenido del di-aminoácido cistina. De hecho, la cisteína y la metionina son los únicos aminoácidos producidos de forma natural contenedores de azufre. Los enlaces de este pueden formar puentes disulfuro, en las que las dos moléculas de cisteína forman, finalmente, el diaminioácido cistina.
Conociendo estos valores de la cistina, comprendemos ahora que, con un aumento de la concentración de la cistina en los folículos pilosos, se obtiene directamente un aumento en la velocidad de crecimiento y del grosor de las fibras capilares.
Metionina:
Es un aminoácido esencial para el crecimiento del cabello. Es un potente antioxidante y un almacén de azufre, un ingrediente clave para contrarrestar los trastornos de pelo. Por su función lipotrópica aumenta el flujo sanguíneo en los folículos capilares, promoviendo un mayor crecimiento del cabello.
Astaxantina:
Su poder antioxidante es 800 veces más potente que la coenzima Q10 y 6000 veces más potente que la vitamina C. Es una explosión antioxidante para todas las células.
Renueva la piel y aumenta su salud, mejora la salud del tejido conectivo, interviene y mejora la salud de las membranas celulares sanas tras la exposición a la luz UV, Ayuda a mantener un equilibrio antioxidante.
Melatonina:
La melatonina, esa hormona universalmente conocida por su poder para regular los ritmos circadianos, también está implicada en el crecimiento del cabello. Hasta ahora, a nivel popular, se la vinculaba con su capacidad para facilitar el sueño, pero la ciencia lleva tiempo investigando su relación con el pelo. Y hay buenas noticias, ya que según el estudio Melatonin and hair physiology del doctor Massimo Milani, se han demostrado sus actividades antioxidantes y antiinflamatorias en la piel y su implicación en el crecimiento del pelo para promover su fase anágena y atenuar el estrés oxidativo del folículo piloso.
Biotina:
La biotina mejora la infraestructura de la queratina, una proteína básica que compone el cabello, la piel y las uñas, así que puede mejorar la salud del cabello, incluyendo el volumen y la cobertura del cuero cabelludo
Retinol:
La vitamina A y sus derivados (retinoides) son importantes para el desarrollo y mantenimiento de múltiples tejidos epiteliales, incluidos la piel, el cabello y las glándulas sebáceas, ya que se observan efectos adversos graves en la deficiencia o exceso de vitamina A.
Aumenta el flujo sanguíneo a los folículos capilares y estimula la formación de nuevos vasos sanguíneos.
Castaño de indias:
Sus compuestos flavonoides son reconocidos por actuar como un potente antioxidante que puede proteger del daño celular. Más aún, sus propiedades antiinflamatorias, astringentes y tónicas resultan efectivas para la piel. De allí que existan tantos productos con fórmulas para reafirmar, tonificar la piel y ayudar a reducir las líneas de expresión. Por ejemplo: cremas corporales, lociones, tónicos limpiadores e hidratantes.
Asimismo, esta planta contribuye al fortalecimiento del cuero cabelludo al mejorar el riego sanguíneo capilar, favoreciendo el crecimiento del pelo y disminuyendo su caída.
Hierro:
Es el mineral encargado de producir hemoglobina, que son las proteínas que transportan el oxígeno al resto del cuerpo. Uno de sus beneficios es que permite transportan oxígeno a las raíces del pelo, por lo que influye en un pelo más sano y fuerte.
Selenio:
El selenio, agente antiinfeccioso, alivia el prurito y la descamación del cuero cabelludo y remueve las partículas secas y escamosas que se denominan comúnmente caspa o seborrea.
Colágeno:
El colágeno representa un ingrediente fundamental para lucir un cabello sano y fuerte. Esta sustancia, que el cuerpo genera de forma natural, tienden a desaparecer con la edad, haciendo que el pelo se vea apagado, débil y quebradizo.
Mantiene el pelo fuerte y resistente: gracias a su aporte extra de aminoácidos, el cabello recibe los nutrientes que necesita para estar sano.
Contrarresta la caída: el colágeno aporta nutrientes a las células de la raíz, frenando la caída del cabello.
Ayuda a acelerar el crecimiento: al mejorar la circulación en la zona, el pelo crece con más velocidad.
En definitiva, la principal ventaja de asumir colágeno es que actúa regenerando el cabello en profundidad.
Zinc:
Para comprender el vínculo entre la salud del cabello y el zinc, primero es necesario entender la conexión entre la insuficiencia de zinc y la pérdida del cabello. La falta de zinc es, en realidad, la principal causante del deterioro de la estructura de la proteína que compone el folículo piloso. Este debilitamiento del folículo a su vez puede causar el deterioro del cabello y la alopecia capilar.
También se ha demostrado que el zinc juega un papel crucial en la producción de ADN y ARN, siendo necesario para la división de las células de los folículos pilosos y para un crecimiento capilar más saludable.
Al mismo tiempo, el zinc ayuda a mantener equilibrados los niveles hormonales, lo que hace que sea una de las razones esenciales por las que se considera tan efectivo para prevenir la caída del cabello y la aparición de canicie. El cabello envejecido y canoso puede volver a su color original cuando se nutre con dietas ricas en zinc o suplementos formulados con este elemento.
Molibdeno:
El molibdeno es responsable del metabolismo de los aminoácidos sulfurosos, en particular metionina, esenciales para la síntesis de queratina.
El molibdeno es un mineral que necesitamos para mantenernos sanos. El organismo usa el molibdeno para procesar las proteínas y el material genético como el ADN. El molibdeno también ayuda a descomponer los medicamentos y las sustancias tóxicas que entran al organismo.
De forma más concreta, estos elementos participarán en la siguiente composición en peso:
• Sabal entre 100 y 200mg.
• Pygeum afrícanum entre 50 y 100 mg.
• Cistina entre 200 y 300mg.
• Metionina entre 50 y 125 mg.
• Astaxantina entre 4 y 8mg.
• Melatonina entre 0,2 y 1mg.
• Castaño de indias entre 10 y 50mg.
• Hierro entre 6 y 14 mg.
• Colágeno entre 10 y 40mg.
• Zinc entre 5 y 10mg.
• Biotina entre 5 y 50ng (Nanogramos).
• Retinol entre 300 y 800ng (Nanogramos).
• Molibdeno entre 5 y 25ng (Nanogramos).
• Selenio entre 10 y 55ng (Nanogramos). El producto así descrito será de toma oral, con dosis diarias, ya sea en forma líquida o sólida en cualquier formato para ingestión oral, pudiéndose obtener en comprimidos, grageas, pastillas, cápsulas duras o blandas.
En el caso de obtenerse en cápsulas, estas pueden contener en su exterior material vegetal o animal, así como glicerina para su recubrimiento.
Se consigue de esta manera un complejo nutricional capilar sumamente efectivo para el tratamiento del cabello.
EJEMPLO DE REALIZACIÓN PRÁCTICA DE LA INVENCIÓN
A modo de ejemplo, para obtener 435,20032 mg de complejo nutricional capilar se emplean los siguientes componentes:
• Sabal 100 mg.
• Pygeum afrícanum ... 50 mg.
Cistina 200 mg.
• Metionina 50 mg.
• Astaxantina 4 mg.
• Melatonina 0,2 mg.
• Castaño de indias 10mg.
• Hierro 6 mg.
• Colágeno 10 mg.
• Zinc 5 mg.
• Biotina 5 ng (Nanogramos).
• Retinol 300 ng (Nanogramos).
• Molibdeno 5 ng (Nanogramos).
• Selenio 10 ng (Nanogramos).
Tal y como se ha dicho anteriormente, el compuesto puede fabricarse en formato líquido o en comprimidos, grageas, pastillas, cápsulas duras o blandas, determinando un compuesto para estimulación de la unidad folicular en humanos mediante recursos naturales.

Claims

REIVINDICACIONES a.- Complejo nutñcional capilar, caracterizado por que presenta la siguiente composición:
• Sabal ..entre 100 y 200mg.
• Pygeum africanum > entre 50 y 100 mg.
• Cistina> entre 200 y 300mg
• Metionina> entre 50 y 125 mg.
• Astaxantina> entre 4 y 8mg.
• Melatonina> entre 0,2 y 1mg.
• Castaño de indias> entre 10 y 50mg.
• Hierro> entre 6 y 14 mg.
• Colágeno > entre 10 y 40mg.
• Zinc> entre 5 y 10mg.
• Biotina> entre 5 y 50ng.
• Retinol> entre 300 y 800ng.
• Molibdeno> entre 5 y 25ng.
• Selenio... . entre 10 y 55ng.
PCT/ES2024/070302 2023-06-07 2024-05-21 Complejo nutricional capilar Ceased WO2024252040A1 (es)

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5972345A (en) * 1999-05-03 1999-10-26 Chizick; Stephen Natural preparation for treatment of male pattern hair loss
WO2010015556A1 (en) * 2008-08-04 2010-02-11 Polichem Sa Film-forming liquid formulations for drug release to hair and scalp
US20110287061A1 (en) * 2010-05-20 2011-11-24 Cathy Beggan Dietary composition and method for promoting healthy hair growth and melanogenesis
GB2484812A (en) * 2010-10-19 2012-04-25 Pangaea Lab Ltd Composition for reducing hair loss/improving hair condition
US8221746B2 (en) * 2008-05-02 2012-07-17 Elliot James Isaacs Antioxidant for use in cosmetic, medicated and pharmaceutical preparations
US10688037B1 (en) * 2015-12-31 2020-06-23 Nutraceutical Wellness Inc. Compositions and method for hair regrowth

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5972345A (en) * 1999-05-03 1999-10-26 Chizick; Stephen Natural preparation for treatment of male pattern hair loss
US8221746B2 (en) * 2008-05-02 2012-07-17 Elliot James Isaacs Antioxidant for use in cosmetic, medicated and pharmaceutical preparations
WO2010015556A1 (en) * 2008-08-04 2010-02-11 Polichem Sa Film-forming liquid formulations for drug release to hair and scalp
US20110287061A1 (en) * 2010-05-20 2011-11-24 Cathy Beggan Dietary composition and method for promoting healthy hair growth and melanogenesis
GB2484812A (en) * 2010-10-19 2012-04-25 Pangaea Lab Ltd Composition for reducing hair loss/improving hair condition
US10688037B1 (en) * 2015-12-31 2020-06-23 Nutraceutical Wellness Inc. Compositions and method for hair regrowth

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