WO2024254017A8 - Peptides agrafés et procédés associés - Google Patents

Peptides agrafés et procédés associés

Info

Publication number
WO2024254017A8
WO2024254017A8 PCT/US2024/032319 US2024032319W WO2024254017A8 WO 2024254017 A8 WO2024254017 A8 WO 2024254017A8 US 2024032319 W US2024032319 W US 2024032319W WO 2024254017 A8 WO2024254017 A8 WO 2024254017A8
Authority
WO
WIPO (PCT)
Prior art keywords
methods
stapled peptides
stapled
peptides
formulations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2024/032319
Other languages
English (en)
Other versions
WO2024254017A2 (fr
WO2024254017A3 (fr
Inventor
Keith William ORFORD
Lihua Yu
Theodore Anael MARTINOT
Jonathan Barry Hurov
Yaguang Si
Xinwei Han
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Parabilis Medicines Inc
Original Assignee
Parabilis Medicines Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Parabilis Medicines Inc filed Critical Parabilis Medicines Inc
Priority to CN202480050901.3A priority Critical patent/CN121620379A/zh
Priority to AU2024284126A priority patent/AU2024284126A1/en
Priority to KR1020257041985A priority patent/KR20260035134A/ko
Publication of WO2024254017A2 publication Critical patent/WO2024254017A2/fr
Publication of WO2024254017A3 publication Critical patent/WO2024254017A3/fr
Priority to IL325050A priority patent/IL325050A/en
Publication of WO2024254017A8 publication Critical patent/WO2024254017A8/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)

Abstract

Entre autres, la présente divulgation concerne des technologies comprenant de I à 66 formulations, des compositions, des procédés, etc. pour traiter divers cancers.
PCT/US2024/032319 2023-06-06 2024-06-03 Peptides agrafés et procédés associés Ceased WO2024254017A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CN202480050901.3A CN121620379A (zh) 2023-06-06 2024-06-03 订书钉化肽及其方法
AU2024284126A AU2024284126A1 (en) 2023-06-06 2024-06-03 Stapled peptides and methods thereof
KR1020257041985A KR20260035134A (ko) 2023-06-06 2024-06-03 스테이플화 펩티드 및 이의 방법
IL325050A IL325050A (en) 2023-06-06 2025-12-01 Clamped peptides and methods thereof

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US202363471492P 2023-06-06 2023-06-06
US63/471,492 2023-06-06
US202363510357P 2023-06-26 2023-06-26
US63/510,357 2023-06-26

Publications (3)

Publication Number Publication Date
WO2024254017A2 WO2024254017A2 (fr) 2024-12-12
WO2024254017A3 WO2024254017A3 (fr) 2025-04-24
WO2024254017A8 true WO2024254017A8 (fr) 2025-12-04

Family

ID=93794644

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2024/032319 Ceased WO2024254017A2 (fr) 2023-06-06 2024-06-03 Peptides agrafés et procédés associés

Country Status (5)

Country Link
KR (1) KR20260035134A (fr)
CN (1) CN121620379A (fr)
AU (1) AU2024284126A1 (fr)
IL (1) IL325050A (fr)
WO (1) WO2024254017A2 (fr)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012040459A2 (fr) * 2010-09-22 2012-03-29 President And Fellows Of Harvard College Peptides de ciblage de la béta-caténine et leurs utilisations
CN111372942A (zh) * 2017-09-07 2020-07-03 弗格制药有限公司 调节β-联蛋白功能的物质及其方法
MX2023014679A (es) * 2021-06-08 2024-01-15 Fog Pharmaceuticals Inc Peptidos grapados y metodos para su obtencion.

Also Published As

Publication number Publication date
WO2024254017A2 (fr) 2024-12-12
IL325050A (en) 2026-02-01
WO2024254017A3 (fr) 2025-04-24
AU2024284126A1 (en) 2025-12-11
KR20260035134A (ko) 2026-03-12
CN121620379A (zh) 2026-03-06

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