WO2024254483A3 - Génération de populations de sang humain et de progéniteurs de vaisseaux sanguins à partir de cellules souches pluripotentes - Google Patents

Génération de populations de sang humain et de progéniteurs de vaisseaux sanguins à partir de cellules souches pluripotentes Download PDF

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WO2024254483A3
WO2024254483A3 PCT/US2024/033057 US2024033057W WO2024254483A3 WO 2024254483 A3 WO2024254483 A3 WO 2024254483A3 US 2024033057 W US2024033057 W US 2024033057W WO 2024254483 A3 WO2024254483 A3 WO 2024254483A3
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stem cells
progenitors
pluripotent stem
blood
blood vessel
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WO2024254483A2 (fr
WO2024254483A9 (fr
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Kyle M. LOH
Jonas FOWLER
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Leland Stanford Junior University
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Leland Stanford Junior University
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Publication of WO2024254483A9 publication Critical patent/WO2024254483A9/fr
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    • C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells

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Abstract

Sont proposés des procédés pour la différenciation efficace de hPSC en cellules souches hématopoïétiques dans des conditions monocouche définies. La présente divulgation propose également des systèmes, des compositions et des kits pour mettre en œuvre les procédés de la divulgation.
PCT/US2024/033057 2023-06-08 2024-06-07 Génération de populations de sang humain et de progéniteurs de vaisseaux sanguins à partir de cellules souches pluripotentes Ceased WO2024254483A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363471931P 2023-06-08 2023-06-08
US63/471,931 2023-06-08

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WO2024254483A2 WO2024254483A2 (fr) 2024-12-12
WO2024254483A3 true WO2024254483A3 (fr) 2025-01-16
WO2024254483A9 WO2024254483A9 (fr) 2025-11-06

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PCT/US2024/033057 Ceased WO2024254483A2 (fr) 2023-06-08 2024-06-07 Génération de populations de sang humain et de progéniteurs de vaisseaux sanguins à partir de cellules souches pluripotentes

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190270967A1 (en) * 2016-06-16 2019-09-05 The Regents Of The University Of California Identification of factor that promotes human hsc self-renewal
US20230159894A1 (en) * 2020-04-06 2023-05-25 The Board Of Trustees Of The Leland Stanford Junior University Generating populations of human blood and blood vessel progenitors from pluripotent stem cells

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190270967A1 (en) * 2016-06-16 2019-09-05 The Regents Of The University Of California Identification of factor that promotes human hsc self-renewal
US20230159894A1 (en) * 2020-04-06 2023-05-25 The Board Of Trustees Of The Leland Stanford Junior University Generating populations of human blood and blood vessel progenitors from pluripotent stem cells

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
FOWLER JONAS L., ZHENG SHERRY LI, NGUYEN ALANA, CHEN ANGELA, XIONG XIAOCHEN, CHAI TIMOTHY, CHEN JULIE Y., KARIGANE DAIKI, BANUELOS: "Lineage-tracing hematopoietic stem cell origins in vivo to efficiently make human HLF+ HOXA+ hematopoietic progenitors from pluripotent stem cells", DEVELOPMENTAL CELL, CELL PRESS, US, vol. 59, no. 9, 1 May 2024 (2024-05-01), US , pages 1110 - 1131.e22, XP093266825, ISSN: 1534-5807, DOI: 10.1016/j.devcel.2024.03.003 *

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WO2024254483A9 (fr) 2025-11-06

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