WO2025000204A1 - 一种生物特征信息检测装置和电子设备 - Google Patents

一种生物特征信息检测装置和电子设备 Download PDF

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Publication number
WO2025000204A1
WO2025000204A1 PCT/CN2023/102523 CN2023102523W WO2025000204A1 WO 2025000204 A1 WO2025000204 A1 WO 2025000204A1 CN 2023102523 W CN2023102523 W CN 2023102523W WO 2025000204 A1 WO2025000204 A1 WO 2025000204A1
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WO
WIPO (PCT)
Prior art keywords
finger
connecting plate
analog front
blood pressure
biometric information
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2023/102523
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English (en)
French (fr)
Inventor
程树青
丘芳芳
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shenzhen Goodix Technology Co Ltd
Original Assignee
Shenzhen Goodix Technology Co Ltd
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Filing date
Publication date
Application filed by Shenzhen Goodix Technology Co Ltd filed Critical Shenzhen Goodix Technology Co Ltd
Priority to EP23822225.1A priority Critical patent/EP4512316A4/en
Priority to PCT/CN2023/102523 priority patent/WO2025000204A1/zh
Priority to US18/541,084 priority patent/US20240423488A1/en
Publication of WO2025000204A1 publication Critical patent/WO2025000204A1/zh
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/022—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
    • A61B5/02233—Occluders specially adapted therefor
    • A61B5/02241—Occluders specially adapted therefor of small dimensions, e.g. adapted to fingers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/02108—Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/02141—Details of apparatus construction, e.g. pump units or housings therefor, cuff pressurising systems, arrangements of fluid conduits or circuits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/024—Measuring pulse rate or heart rate
    • A61B5/02416—Measuring pulse rate or heart rate using photoplethysmograph signals, e.g. generated by infrared radiation
    • A61B5/02427—Details of sensor
    • A61B5/02433—Details of sensor for infrared radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/024—Measuring pulse rate or heart rate
    • A61B5/02438—Measuring pulse rate or heart rate with portable devices, e.g. worn by the patient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14552—Details of sensors specially adapted therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813—Specially adapted to be attached to a specific body part
    • A61B5/6825—Hand
    • A61B5/6826—Finger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/683—Means for maintaining contact with the body
    • A61B5/6838—Clamps or clips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/04—Constructional details of apparatus
    • A61B2560/0406—Constructional details of apparatus specially shaped apparatus housings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/04—Constructional details of apparatus
    • A61B2560/0462—Apparatus with built-in sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0247—Pressure sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/16—Details of sensor housings or probes; Details of structural supports for sensors
    • A61B2562/168—Fluid filled sensor housings

Definitions

  • the present application relates to the technical field of wearable devices, and more specifically, to a biometric information detection device and an electronic device.
  • the mercury sphygmomanometer is the gold standard in the field of blood pressure measurement. It requires users to have certain professional knowledge, and users can also make dynamic adjustments based on the actual situation of the tester, so the test results are accurate and applicable to a wide range of people.
  • the electronic sphygmomanometers on the market do not require professional personnel to use and operate, due to their large overall size, they are generally suitable for placement at home and cannot be carried around, so they cannot meet the real-time blood pressure management needs of people with hypertension.
  • a first aspect of an embodiment of the present application provides a biometric information detection device, comprising:
  • a finger cot comprising a mechanical structure or an air bag, the mechanical structure or the air bag being used to fix the finger cot on the user's finger;
  • a pulse wave sensor comprising a light emitter and a photodiode
  • the light emitter is used to emit a light signal
  • the light signal is reflected or transmitted by the object to be detected and reaches the photodiode
  • the photodiode is used to convert the received light signal into an electrical signal
  • An analog front end is electrically connected to the pulse wave sensor, and the analog front end is used to receive the electrical signal and output an analog front end signal;
  • a micro control unit is electrically connected to the analog front end, and is used to receive the analog front end signal and output biometric information, wherein the biometric information includes a blood pressure value.
  • the device further includes a pressure detector, and the pressure detector is electrically connected to the analog front end.
  • the finger sleeve is of a through-type at both ends, and the cross-section of the through-type finger sleeve is annular.
  • the finger sleeve is of a non-through type
  • the non-through finger cot is provided with an opening only at one end;
  • the cross section of the non-through type finger sleeve is one of a rectangular, circular, elliptical and polygonal shape, and the non-through type finger sleeve has an internal space, and the internal space is used to accommodate the user's finger.
  • the finger sleeve further includes an air conduit, and the air conduit is connected to the air bag.
  • the mechanical structure includes a spring structure, and the spring structure includes a spring body and a connecting plate;
  • the connecting plate is connected to one end of the spring body, the other end of the spring body is connected to the finger sleeve, and the spring structure is arranged on one side of the finger sleeve close to the opening.
  • the spring body includes a first spring body and a second spring body
  • the connecting plate includes a first connecting plate and a second connecting plate
  • the first connecting plate is connected to the first spring body
  • the second connecting plate is connected to the second spring body
  • the light emitter is arranged on the first connecting plate
  • the photodiode is arranged on the second connecting plate.
  • the mechanical structure or the airbag is disposed inside the finger sleeve on a side close to the opening.
  • the mechanical structure includes a motor structure
  • the motor structure includes a motor and a connecting plate
  • the connecting plate is connected to the motor
  • the motor is used to control the movement of the connecting plate
  • the motor structure is arranged on a side of the finger sleeve close to the opening.
  • the biometric information further includes at least one of a heart rate value and a blood oxygen value.
  • An electronic device provided in the second aspect of an embodiment of the present application includes any one of the biometric information detection devices provided in the first aspect of the embodiment of the present application, and a display screen, wherein the display screen is arranged on the outer surface of the device, and the display screen is used to display the biometric information.
  • the electronic device includes a smart ring, a finger-clip blood pressure meter, a finger-clip blood pressure oximeter, and a finger-clip multi-parameter meter.
  • the present invention provides a biometric information detection device that can measure blood pressure based on fingers. It can accurately measure blood pressure with a smaller volume, realizing the miniaturization of blood pressure measuring device, making it convenient for users to carry it with them.
  • the embodiments of the present application also provide an electronic device that can facilitate hypertensive users to quickly and conveniently monitor real-time blood pressure in a non-home environment, thereby improving the user experience.
  • FIG. 1 is a schematic diagram of a finger blood vessel changing from dilation to pressurization and then returning to dilation.
  • FIG. 2 is a schematic diagram of the structure of a biometric information detection device provided in an embodiment of the present application.
  • FIG. 3 is a schematic diagram of the structure of another biometric information detection device provided in an embodiment of the present application.
  • FIG. 4 is a schematic diagram of the structure of another biometric information detection device provided in an embodiment of the present application.
  • FIG. 5 is a PPG waveform amplitude curve diagram of a blood vessel during a process from complete contraction to recovery of relaxation.
  • FIG. 6 is a schematic diagram of calculating blood pressure using a double Gaussian fitting method.
  • FIG. 7 is a schematic diagram of blood pressure detection results of a biometric information detection device at the third joint of a finger provided in an embodiment of the present application.
  • FIG8 is a schematic diagram of blood pressure detection results of a biometric information detection device at the second joint of a finger provided in an embodiment of the present application.
  • FIG. 9 is a structural block diagram of an electronic device provided in an embodiment of the present application.
  • FIG. 10 is a schematic diagram of an electronic device provided in an embodiment of the present application.
  • first”, “second”, etc. are only used to distinguish similar objects, and cannot be understood as indicating or implying relative importance, or implicitly indicating the number of technical features indicated. Therefore, a feature defined as “first”, “second”, etc. may explicitly or implicitly include one or more of the features.
  • FIG. 1 shows a schematic diagram of a finger blood vessel changing from dilation to pressurization and then returning to dilation.
  • the finger 10 includes bones 101 and blood vessels 102.
  • the blood vessels 102 are in a dilated state.
  • the blood vessels 102 on both sides of the finger 10 gradually change from a dilated state to a compressed state, as shown in FIG1(b), at which time the blood flow in the blood vessels 102 decreases to a state that is almost cut off.
  • the pressure applied to the finger 10 is gradually released, as shown in FIG1(c)
  • the blood vessels 102 gradually return from a compressed state to a dilated state.
  • the pressure value at that time and the pressure pulse wave or photoelectric pulse wave of the blood vessel 102 are synchronously recorded.
  • the waveforms of pressure pulse wave and photoelectric pulse wave have similar morphological characteristics, because pressure pulse wave and photoelectric pulse wave are actually two different manifestations of the same arterial periodic pulsation process, and essentially reflect the functional state of the cardiovascular system. Therefore, by analyzing and studying the characteristics of pressure pulse wave or photoelectric pulse wave signals, the physiological and pathological information contained therein can be extracted to provide assistance for the early diagnosis and prevention of cardiovascular system-related diseases.
  • the pressure pulse wave is usually detected and obtained at the superficial arteries such as the radial artery, carotid artery or femoral artery.
  • the pressure detector is used to record the curve of the change of arterial pressure over time to obtain the pressure pulse wave waveform.
  • the photoelectric pulse wave is generally detected and obtained using a photoelectric sensor, so it is often called a photoelectric volumetric pulse wave. It is usually detected by photoelectric volumetric pulse wave recording (PPG).
  • PPG photoelectric volumetric pulse wave recording
  • the curve of blood volume change over time recorded by this method is the photoelectric pulse wave waveform.
  • the photoelectric pulse wave waveform is also written as the PPG waveform below.
  • the waveform of the pressure pulse wave or the photoelectric pulse wave during the pressurization or recovery process relevant features are extracted, such as the peak value of the PPG waveform, and drawn into an envelope curve.
  • the point with the maximum amplitude is the mean blood pressure (MBP)
  • MBP mean blood pressure
  • DBP diastolic blood pressure
  • SBP systolic blood pressure
  • DBP diastolic blood pressure
  • Figure 2 shows a structural schematic diagram of a biometric information detection device provided in an embodiment of the present application
  • Figure 3 shows a structural schematic diagram of another biometric information detection device provided in an embodiment of the present application
  • Figure 4 shows a structural schematic diagram of yet another biometric information detection device provided in an embodiment of the present application.
  • the embodiment of the present application provides a biometric information detection device 20, and the device 20 includes:
  • the finger sleeve 200 includes a mechanical structure 24 or an air bag 25 .
  • the mechanical structure 24 or the air bag 25 is used to fix the finger sleeve 200 on the finger 10 of the user.
  • the finger sleeve 200 is a through-type finger sleeve.
  • the cross section of the finger sleeve 202 is annular, and the annular shape includes a circular ring, a triangular ring, a square ring, an elliptical ring, and a wavy ring.
  • the finger sleeve 202 in FIG4 is similar to a ring, and the user can wear the two-end through-type finger sleeve 202 on the third knuckle (as shown in FIG4 (a)) or the second knuckle (as shown in FIG4 (b)) of the finger 10 to conveniently and quickly perform blood pressure detection.
  • the finger sleeve 200 is a non-through type, that is, the non-through type finger sleeve 201 is only provided with an opening at one end, the cross section of the non-through type finger sleeve 201 is one of a rectangular, circular, elliptical and polygonal shape, and the non-through type finger sleeve 201 has an internal space, and the internal space is used to accommodate the user's finger 10.
  • the non-through type finger sleeve 201 is less affected by ambient light, and can achieve high-accuracy blood pressure detection while meeting the requirements of convenience and speed.
  • both the two-end through-type finger sleeve 202 and the non-through-type finger sleeve 201 may include the mechanical structure 24 or the airbag 25 .
  • the mechanical structure 24 or the airbag 25 is disposed inside the finger sleeve 200 at a side close to the opening.
  • the opening side of the non-through type finger cover 201 is close to the third knuckle of the finger 10, and the mechanical structure 24 or the airbag 25 is arranged on the side close to the opening inside the non-through type finger cover 201, so that the waveform of the pressure pulse wave or the photoelectric pulse wave of the third knuckle can be collected.
  • the finger sleeve 200 includes the airbag 25 and an air duct 270 , wherein the air duct 270 is connected to the airbag 25 , and the air duct 270 can inflate and deflate the airbag 25 .
  • the finger cot 200 includes the mechanical structure 24, and the mechanical structure 24 is used to fix the finger cot 200 on the user's finger 10.
  • the mechanical structure 24 includes a spring structure 240, and the spring structure 240 includes a spring body 241 and a connecting plate 242.
  • the connecting plate 242 is connected to one end of the spring body 241, and the other end of the spring body 241 is connected to the finger cot 200, and the spring structure 240 is arranged on one side of the finger cot 200 near the opening.
  • the spring body 241 includes a first spring body 2411 and a second spring body 2412
  • the connecting plate 242 includes a first connecting plate 2421 and a second connecting plate 2422 ;
  • the first connecting plate 2421 is connected to the first spring body 2411, and the second connecting plate 2422 is connected to the second spring body 2412 , the first connecting plate 2421 is provided with a light emitter 211 , and the second connecting plate 2422 is provided with a photodiode 212 .
  • the mechanical structure 24 includes a motor structure, the motor structure includes a motor and a connecting plate, the connecting plate is connected to the motor, the motor is used to control the movement of the connecting plate, and the motor structure is arranged on a side of the finger sleeve 200 near the opening.
  • the motor can control the connecting plate to pressurize and release the blood vessel 102.
  • the pulse wave sensor 210 includes the light emitter 211 and the photodiode 212.
  • the light emitter 211 is used to emit a light signal.
  • the light signal is reflected or transmitted by the object to be detected and reaches the photodiode 212.
  • the photodiode 212 is used to convert the received light signal into an electrical signal.
  • the light signal emitted by the light emitter 211 passes through the muscles, bones, veins and other connecting tissues of the finger 10 and is received by the photodiode 212 .
  • the light signal emitted by the light emitter 211 passes through the skin tissue of the finger 10 and then reflects to the photodiode 212 .
  • An analog front end (Analog Front End, AFE) 220 wherein the analog front end 220 is electrically connected to the pulse wave sensor 210, and the analog front end 220 is used to receive the electrical signal and output an analog front end signal.
  • the analog front end 220 can amplify, filter, and perform analog-to-digital (AD) conversion on the electrical signal sensed by the pulse wave sensor 210, and the processed signal is the analog front end signal.
  • AD analog-to-digital
  • a microcontroller unit (MCU) 230 is electrically connected to the analog front end 220, and the microcontroller unit 230 is used to receive the analog front end signal and output biometric information, wherein the biometric information includes a blood pressure value.
  • the microcontroller unit MCU can process the analog front-end signal through the traditional double Gaussian fitting method or envelope inflection point method or deep learning algorithm, and then obtain the blood pressure values including systolic pressure SBP and diastolic pressure DBP.
  • the biometric information also includes at least one of a heart rate value and a blood oxygen value.
  • the pulse wave sensor 210 can be used for blood pressure detection and heart rate and blood oxygen detection at the same time, realizing the reuse of the pulse wave sensor 210, thereby simplifying the structure of the device 20 and saving energy. Approx. cost.
  • the device 20 further includes a pressure detector 260 , and the pressure detector 260 is electrically connected to the analog front end 220 .
  • the pressure detector 260 can be used to measure the pressure pulse wave, and then the blood pressure value is calculated based on the pressure pulse wave, while the pulse wave sensor 210 will be used to measure the heart rate value and the blood oxygen value.
  • the pressure detector 260 and the pulse wave sensor 210 can be combined to measure the blood pressure value, and two initial blood pressure values can be calculated according to the pressure pulse wave measured by the pressure detector 260 and the photoelectric pulse wave measured by the pulse wave sensor 210, respectively, and then the two initial blood pressure values are processed, for example, an average value is taken, to obtain the target blood pressure value.
  • the pressure detector 260 and the pulse wave sensor 210 are used to calculate the blood pressure value at the same time, which can improve the accuracy of the blood pressure value calculation result.
  • the pressure detector 260 can also be used in the device 20 including FIG. 2 , and the embodiment of the present application does not limit the application scope of the pressure detector 260 .
  • FIG. 5 is a PPG waveform amplitude curve diagram of a blood vessel during a process from complete contraction to recovery of relaxation.
  • the photoelectric pulse wave amplitude curve is obtained by applying pressure to the finger 10 to achieve the blocking process of the blood vessel 102.
  • the curve characteristics are obtained in multiple dimensions through curve fitting.
  • the curve fitting parameters Parameter 1, Parameter 2, Parameter 3, etc. in FIG. 5
  • the final blood pressure result is obtained, i.e., the systolic pressure SBP and the diastolic pressure DBP in FIG. 5 .
  • the PPG waveform amplitude curve is shown in FIG. 5 , with the abscissa being the pressure and the ordinate being the PPG waveform amplitude.
  • the general calculation method of the oscillometric method is: the pressure corresponding to the point where the vascular volume changes the most is the mean blood pressure MBP, and then the intrinsic relationship between the systolic pressure SBP, diastolic pressure DBP and mean blood pressure MBP is determined based on the characteristics of the envelope curve, and finally the blood pressure result is obtained.
  • Figure 6 is a schematic diagram of calculating blood pressure using a double Gaussian fitting method. Combining Figures 5 and 6, the method for calculating the blood pressure result is as follows:
  • A1 and B1 are the ordinate and abscissa of the peak point of the envelope curve respectively
  • A2 is the ordinate of the intersection of the envelope curve and the y-axis
  • B2 is the difference between the abscissa of the peak point and the point on the envelope curve that is located on the left side of the peak point and is half the height of the peak point (which can be called the left half-width point)
  • B3 is the difference between the abscissa of the peak point and the point on the envelope curve that is located on the right side of the peak point and is half the height of the peak point (which can be called the right half-width point).
  • the principle of the envelope inflection point method is: the elasticity of the artery is the largest under the condition of zero transmural pressure, and there are two inflection points on the left and right sides of the peak point of the pressure pulse wave envelope curve.
  • the cuff pressures corresponding to these two inflection points are systolic pressure SBP and diastolic pressure DBP, respectively.
  • the pressure change corresponding to the inflection point is the largest, so the absolute value of the first-order derivative of the corresponding envelope curve is the maximum value, and the value of the second-order derivative of the corresponding envelope curve should be 0.
  • the two inflection points on the left and right sides of the peak point of the envelope curve can be found, thereby calculating the systolic pressure SBP and the diastolic pressure DBP respectively.
  • FIG. 7 and FIG. 8 are schematic diagrams of blood pressure detection results at the third and second joints of a finger by a biometric information detection device provided in an embodiment of the present application.
  • the horizontal axis represents different measured objects
  • the vertical axis represents the blood pressure value
  • the unit of the blood pressure value is millimeter of mercury (mmHg).
  • SBP0 and DBP0 represent the true values of systolic and diastolic blood pressure recorded using a mercury stethoscope
  • SBP1 and DBP1 represent the values of systolic and diastolic blood pressure calculated by collecting pressure pulse waves at the knuckles.
  • Table 2 gives the accuracy evaluation results of the blood pressure data measured at the third knuckle and the second knuckle, respectively.
  • MD median deviation
  • SD standard deviation
  • the accuracy evaluation results of blood pressure data measured at the third and second knuckles can be seen in Table 2.
  • the absolute values of the median difference SBP_MD of systolic blood pressure SBP and the median difference DBP_MD of diastolic blood pressure DBP are both less than 5
  • the absolute values of the standard deviation SBP_SD of systolic blood pressure SBP and the standard deviation DBP_SD of diastolic blood pressure DBP are both less than 8, which meets the ISO medical standards.
  • the biometric information detection device 20 provided in the embodiment of the present application measures blood pressure at the third knuckle and the second knuckle, and the accuracy of the blood pressure data obtained meets the standard.
  • FIG. 9 is a structural block diagram of an electronic device provided in an embodiment of the present application.
  • an embodiment of the present application also provides an electronic device 40, which includes the biometric information detection device 20 provided in the above-mentioned embodiment of the present application, and a display screen 30, wherein the display screen 30 is arranged on the outer surface of the device 20, and the display screen 30 is used to display the biometric information.
  • the biometric information displayed on the display screen 30 includes blood pressure value, blood oxygen value and heart rate value.
  • the display screen 30 can display the blood pressure value alone or simultaneously.
  • the wearable device also includes a smart ring, a finger-clip blood pressure meter, a finger-clip blood pressure oximeter, a finger-clip multi-parameter meter, and other portable blood pressure measuring devices that can be used on the finger.
  • FIG. 10 is a schematic diagram of an electronic device provided in an embodiment of the present application.
  • the electronic device 40 is a multifunctional finger-clip blood pressure and blood oximeter, which can measure biometric information including heart rate value, blood oxygen value, heart rate variability (HRV) and blood pressure value.
  • biometric information including heart rate value, blood oxygen value, heart rate variability (HRV) and blood pressure value.
  • the electronic device 40 in the embodiment of the present application can facilitate hypertensive users to quickly and conveniently monitor real-time blood pressure in a non-home environment, thereby improving the user experience.

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  • Optics & Photonics (AREA)
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Abstract

一种生物特征信息检测装置，包括手指套、脉搏波传感器、模拟前端、微控制单元。所述手指套包括机械结构或气囊。所述脉搏波传感器包括光发射器和光电二极管。所述模拟前端与所述脉搏波传感器电连接，且所述模拟前端用于接收所述电信号，并输出模拟前端信号。所述微控制单元与所述模拟前端电连接，且所述微控制单元用于接收所述模拟前端信号，并输出生物特征信息，所述生物特征信息包括血压值。所述生物特征信息检测装置可以实现血压测量装置的小型化，方便用户随身携带，实现用户非居家环境下的血压监测。

Description

一种生物特征信息检测装置和电子设备 技术领域
本申请涉及可穿戴设备技术领域，并且更具体地，涉及一种生物特征信息检测装置和电子设备。
背景技术
目前水银血压计是血压测量领域的金标准，要求使用者要有一定专业知识的，使用者也可以根据测试者实际情况进行动态调整，所以测试结果准确，适用人群范围广。虽然目前市场上的电子血压计可以不需要专业人员进行使用操作，但由于其整体体积较大，一般适用于放置在家庭中，不能随身携带，故无法满足高血压人群进行实时的血压管理。
因此，如何实现血压测量装置的小型化，方便用户随身携带，实现用户非居家环境下的血压监测，是一项亟待解决的技术问题。
发明内容
本申请实施例第一方面提供的一种生物特征信息检测装置，包括：
手指套，所述手指套包括机械结构或气囊，所述机械结构或所述气囊用于将所述手指套固定在用户的手指上；
脉搏波传感器，所述脉搏波传感器包括光发射器和光电二极管，所述光发射器用于发射光信号，所述光信号被待检测物体反射或透射后到达所述光电二极管，所述光电二极管用于将接收到的光信号转换成电信号；
模拟前端，所述模拟前端与所述脉搏波传感器电连接，且所述模拟前端用于接收所述电信号，并输出模拟前端信号；
微控制单元，所述微控制单元与所述模拟前端电连接，且所述微控制单元用于接收所述模拟前端信号，并输出生物特征信息，所述生物特征信息包括血压值。
在一种可能的实施方式中，所述装置还包括压力检测器，所述压力检测器与所述模拟前端电连接。
在一种可能的实施方式中，所述手指套为两端贯通型，所述两端贯通型手指套的横截面为环形。
在一种可能的实施方式中，所述手指套为非贯通型；
所述非贯通型手指套仅在一端设置有开口；
所述非贯通型手指套的截面为矩形、圆形、椭圆形和多边形中的一种，且所述非贯通型手指套具有内部空间，所述内部空间用于容纳所述用户的手指。
在一种可能的实施方式中，所述手指套还包括空气导管，所述空气导管和所述气囊连接。
在一种可能的实施方式中，所述机械结构包括弹簧结构，所述弹簧结构包括弹簧本体和连接板；
所述连接板和所述弹簧本体的一端连接，所述弹簧本体的另一端和所述手指套连接，且所述弹簧结构设置在所述手指套内部靠近所述开口的一侧。
在一种可能的实施方式中，所述弹簧本体包括第一弹簧本体和第二弹簧本体，所述连接板包括第一连接板和第二连接板；
所述第一连接板和所述第一弹簧本体连接，所述第二连接板和所述第二弹簧本体连接，所述第一连接板上设置有所述光发射器，所述第二连接板上设置有所述光电二极管。
在一种可能的实施方式中，所述机械结构或所述气囊设置在所述手指套内部靠近所述开口的一侧。
在一种可能的实施方式中，所述机械结构包括电机结构，所述电机结构包括电机和连接板，所述连接板和所述电机连接，所述电机用于控制所述连接板活动，且所述电机结构设置在所述手指套内部靠近所述开口的一侧。
在一种可能的实施方式中，所述生物特征信息还包括心率值和血氧值中的至少一个。
本申请实施例第二方面提供的一种电子设备，包括本申请实施例第一方面提供的任一项生物特征信息检测装置，以及显示屏，所述显示屏设置在所述装置的外表面，所述显示屏用于显示所述生物特征信息。
在一种可能的实施方式中，所述电子设备包括智能戒指，指夹式血压测量仪，指夹式血压血氧测量仪，指夹式多参数测量仪。
本申请实施例提供了生物特征信息检测装置，可以基于手指进行血压测 量，并以较小的体积完成血压的准确测量，实现了血压测量装置的小型化，方便用户随身携带。
本申请实施例还提供了电子设备，可以方便高血压用户在非居家环境下快速便捷的监测实时血压，提升用户体验。
附图说明
图1是一种手指血管从舒张到加压再回到舒张状态的示意图。
图2是本申请实施例提供的一种生物特征信息检测装置的结构示意图。
图3是本申请实施例提供的另一种生物特征信息检测装置的结构示意图。
图4是本申请实施例提供的又一种生物特征信息检测装置的结构示意图。
图5是一种血管从完全收缩到恢复舒张过程中的PPG波形幅值曲线图。
图6是一种双高斯拟合法计算血压的示意图。
图7是本申请实施例提供的一种生物特征信息检测装置在手指第三指节的血压检测结果示意图。
图8是本申请实施例提供的一种生物特征信息检测装置在手指第二指节的血压检测结果示意图。
图9是本申请实施例提供的一种电子设备的结构框图。
图10是本申请实施例提供的一种电子设备的示意图。
具体实施方式
下面将结合附图对本申请实施例中的技术方案进行清楚、完整地描述。
本申请使用的术语是仅仅出于描述特定实施例的目的，而非旨在限制本申请。在本申请和所附权利要求书中所使用的单数形式的“一种”、“所述”和“该”也旨在包括多数形式，除非上下文清楚地表示其他含义。
另外，“第一”、“第二”等术语仅用于区别类似的对象，而不能理解为指示或暗示相对重要性，或者隐含指明所指示的技术特征的数量。由此，限定有“第一”、“第二”等的特征可以明示或者隐含地包括一个或者更多个该特征。
图1展示了一种手指血管从舒张到加压再回到舒张状态的示意图。
如图1(a)所示，手指10包括骨头101和血管102，当所述手指10处于正常的静息状态时，此时所述血管102处于舒张状态。当对所述手指10施加 压力时，所述手指10两侧的所述血管102会从舒张状态逐步变成压缩状态，如图1(b)所示，此时所述血管102的血流变小到几乎截断的状态。随后当施加在所述手指10的压力逐步释放时，如图1(c)所示，此时所述血管102会逐步从压缩状态恢复到舒张状态。
在对所述血管102进行加压或者所述血管102恢复过程中，同步记录此时的压力值和所述血管102的压力脉搏波或光电脉搏波。
压力脉搏波和光电脉搏波的波形图具有相似的形态特征，因为压力脉搏波和光电脉搏波实际上是同一动脉周期性搏动过程的两种不同表现形式，本质上都反映了心血管系统的功能状态。因此，可以通过分析研究压力脉搏波或者光电脉搏波信号的特征，提取其中包含的生理病理信息，为心血管系统相关疾病的早期诊断和预防提供帮助。
压力脉搏波通常在桡动脉、颈动脉或股动脉等浅表动脉处检测获取，利用压力检测器描记动脉压力随时间的变化曲线，得到压力脉搏波波形图。光电脉搏波一般是利用光电传感器检测获取，所以又常称为光电容积脉搏波，通常采用光电容积脉搏波描记(Photo Plethysmography，PPG)法检测得到，采用该方法描记得到的血液容积随时间的变化曲线，即为光电脉搏波波形图，下文将光电脉搏波波形也写为PPG波形。
根据加压或恢复过程中的压力脉搏波或光电脉搏波的波形，提取相关特征，如PPG波形峰值，绘制成包络曲线，根据示波法原理，幅值最大处即为平均血压(Mean Blood Pressure，MBP)，进而可通过传统的双高斯拟合法或包络拐点法或深度学习算法得到收缩压(Systolic Blood Pressure，SBP)和舒张压(Diastolic Blood Pressure，DBP)。
具体的，图2展示了本申请实施例提供的一种生物特征信息检测装置的结构示意图，图3展示了本申请实施例提供的另一种生物特征信息检测装置的结构示意图，图4展示了本申请实施例提供的又一种生物特征信息检测装置的结构示意图。
如图2、图3和图4所示，本申请实施例提供一种生物特征信息检测装置20，所述装置20包括：
手指套200，所述手指套200包括机械结构24或气囊25，所述机械结构24或所述气囊25用于将所述手指套200固定在用户的手指10上。
可选的，请参见图4，所述手指套200为两端贯通型，所述两端贯通型手 指套202的横截面为环形，所述环形包括圆环形、三角环形、方环形、椭圆环形、波浪环形。图4中的手指套202类似戒指，用户可以将所述两端贯通型手指套202戴在所述手指10的第三指节(如图4(a)所示)或第二指节(如图4(b)所示)上，方便快捷的实现血压检测。
可选的，请参见图2和图3，所述手指套200为非贯通型，也就是说所述非贯通型手指套201仅在一端设置有开口，所述非贯通型手指套201的截面为矩形、圆形、椭圆形和多边形中的一种，且所述非贯通型手指套201具有内部空间，所述内部空间用于容纳用户的所述手指10。在日常使用时，所述非贯通型手指套201受到环境光影响比较小，可以实现较高准确度的血压检测，同时又能满足方便快捷的要求。
在本申请实施例中，所述两端贯通型手指套202和所述非贯通型手指套201都可以包括所述机械结构24或所述气囊25。
可选的，所述机械结构24或所述气囊25设置在所述手指套200内部靠近所述开口的一侧。
当所述非贯通型手指套201戴在用户的所述手指10上时，所述非贯通型手指套201开口一侧靠近所述手指10的第三指节部位，所述机械结构24或所述气囊25设置在所述非贯通型手指套201内部靠近所述开口的一侧，可以采集到所述第三指节部位的压力脉搏波或光电脉搏波的波形。
作为一种可选的实施例，请参见图3和图4，所述手指套200包括所述气囊25和空气导管270，所述空气导管270和所述气囊25连接，所述空气导管270可以实现给所述气囊25充气和放气。
作为另一种可选的实施例，所述手指套200包括所述机械结构24，所述机械结构24用于将所述手指套200固定在用户的所述手指10上。所述机械结构24包括弹簧结构240，所述弹簧结构240包括弹簧本体241和连接板242。所述连接板242和所述弹簧本体241的一端连接，所述弹簧本体241的另一端和所述手指套200连接，且所述弹簧结构240设置在所述手指套200内部靠近所述开口的一侧。
具体的，作为一种可选的实施例，请参见图2，所述弹簧本体241包括第一弹簧本体2411和第二弹簧本体2412，所述连接板242包括第一连接板2421和第二连接板2422；
所述第一连接板2421和所述第一弹簧本体2411连接，所述第二连接板 2422和所述第二弹簧本体2412连接，所述第一连接板2421上设置有光发射器211，所述第二连接板2422上设置有光电二极管212。
作为又一种可选的实施例，所述机械结构24包括电机结构，所述电机结构包括电机和连接板，所述连接板和所述电机连接，所述电机用于控制所述连接板活动，且所述电机结构设置在所述手指套200内部靠近所述开口的一侧。所述电机可以控制所述连接板，对所述血管102进行加压和放压操作。
脉搏波传感器210，所述脉搏波传感器210包括所述光发射器211和所述光电二极管212，所述光发射器211用于发射光信号，所述光信号被待检测物体反射或透射后到达所述光电二极管212，所述光电二极管212用于将接收到的光信号转换成电信号。
具体的，请参见图2中所述脉搏波传感器210，在透射型脉搏波传感器210中，所述光发射器211发射的光信号通过所述手指10的肌肉、骨骼、静脉和其他连接组织，被所述光电二极管212接收。
具体的，请参见图4中所述脉搏波传感器210，在反射型脉搏波传感器210中，所述光发射器211发射的光信号透过所述手指10的皮肤组织然后再反射到所述光电二极管212。
模拟前端(Analog Front End，AFE)220，所述模拟前端220与所述脉搏波传感器210电连接，且所述模拟前端220用于接收所述电信号，并输出模拟前端信号。
具体的，所述模拟前端220可以对所述脉搏波传感器210感测的所述电信号进行放大、滤波和模数(Analog-to-Digital，AD)转换等处理，处理后的信号就是所述模拟前端信号。
微控制单元(Microcontroller Unit，MCU)230，所述微控制单元230与所述模拟前端220电连接，且所述微控制单元230用于接收所述模拟前端信号，并输出生物特征信息，所述生物特征信息包括血压值。
可选的，在进行血压检测时，所述微控制单元MCU可通过传统的双高斯拟合法或包络拐点法或深度学习算法对所述模拟前端信号进行处理，然后得到包括收缩压SBP和舒张压DBP的血压值。
作为一种可选的实施例，所述生物特征信息还包括心率值和血氧值中的至少一个。所述脉搏波传感器210可以同时被用于血压检测和心率血氧检测，实现了所述脉搏波传感器210的复用，从而可以简化所述装置20的结构，节 约成本。
可选的，请参见图3和图4，所述装置20还包括压力检测器260，所述压力检测器260与所述模拟前端220电连接。
作为一种可选的实施例，所述压力检测器260可以被用来测量压力脉搏波，然后再根据所述压力脉搏波计算得到血压值，而所述脉搏波传感器210将用来测量心率值和血氧值。
作为另一种可选的实施例，可以将所述压力检测器260和所述脉搏波传感器210结合起来测量血压值，分别根据所述压力检测器260测量出的压力脉搏波和所述脉搏波传感器210测量出的光电脉搏波计算出两个初始血压值，然后再对这两个初始血压值进行处理，例如取平均值，得到目标血压值。在本实施例中，同时用所述压力检测器260和所述脉搏波传感器210来计算血压值，可以提高血压值计算结果的准确度。
值得说明的是，所述压力检测器260除了应用在图3和图4的装置中，还可以应用在包括图2的所述装置20中，本申请实施例没有限定所述压力检测器260的应用范围。
图5是一种血管从完全收缩到恢复舒张过程中的PPG波形幅值曲线图。
具体的，请一并参见图1和图5，以示波法测量血压为例，通过给所述手指10施加压力实现所述血管102阻断过程获取光电脉搏波幅值曲线，通过曲线拟合方式，多维度获取曲线特征，根据曲线拟合参数(图5中的Parameter1、Parameter2、Parameter3....)，获取最终血压结果，即图5中的收缩压SBP和舒张压DBP。PPG波形幅值曲线如图5所示，横坐标为压力，纵坐标为PPG波形幅值。
示波法的一般计算方法为：血管容积变化最大处对应的压力即为平均血压MBP，然后根据包络曲线特征确定收缩压SBP、舒张压DBP和平均血压MBP之间的内在关系，最终得到血压结果。
图6是一种双高斯拟合法计算血压的示意图。结合图5和图6，计算血压结果的方法如下：
首先，通过双高斯函数拟合包络曲线：

其中，A1、B1分别为包络曲线的峰值点的纵坐标和横坐标，A2为包络曲线与y轴交点的纵坐标，B2为包络曲线上位于峰值点左侧且为峰值点高度一半的点(可以称为左半高宽点)与峰值点的横坐标之差，B3为包络曲线上位于峰值点右侧且为峰值点高度一半的点(可以称为右半高宽点)与峰值点的横坐标之差。
然后，得到包络曲线的参数后，由以下公式计算得到舒张压DBP、收缩压SBP、平均血压MBP：


SBP＝2.5*MBP-1.6*DBP
除了用上述的双高斯拟合法计算血压外，还可以选择用包络拐点法计算血压。
具体的，包络拐点法的原理为：动脉在零跨壁压条件下的弹性最大，压力脉搏波包络曲线峰值点左右两侧存在两个拐点，这两个拐点对应的袖套压力分别为收缩压SBP和舒张压DBP，所述拐点对应的压力变化量最大，因此对应包络曲线的一阶导的绝对值为最大值，此时对应的包络曲线的二阶导的值应为0。因此，通过计算压力脉搏波包络曲线的一阶导或者二阶导的值，就可以找到包络曲线峰值点左右两侧的两个拐点，从而分别计算出收缩压SBP和舒张压DBP。
图7和图8分别是本申请实施例提供的一种生物特征信息检测装置在手指第三指节和第二指节的血压检测结果示意图。
在图7和图8中，横坐标代表不同的被测对象，纵坐标代表血压值大小，血压值单位是毫米汞柱(mmHg)。
其中SBP0和DBP0表示使用水银听诊器记录的收缩压和舒张压的真值，SBP1和DBP1表示在指节处采集压力脉搏波计算得到的收缩压和舒张压的值。
从图7和图8中可以看到，在第三指节和第二指节的血压检测结果和使用水银听诊器记录的血压检测结果非常接近，在第三指节和第二指节处进行血压检测具备可行性。
在下面的表1中，在手臂、手腕、第三指节和第二指节等不同部位分别对25个被测对象进行了血压测量，均使用示波法采集压力脉搏波，通过提取 压力脉搏波的波峰进行包络拟合，最后计算出包络峰(Envelope Peak，EP)与收缩压SBP、舒张压DBP和平均动脉压(Mean Arterial Pressure，MAP)的相关系数。
表1
从表1中可以看到在手臂、手腕、第三指节和第二指节测量出的收缩压SBP、舒张压DBP和平均动脉压MAP与包络峰EP的相关系数，不论是对正常血压的被测对象，还是对高血压的被测对象，第三指节和第二指节都与血压有强相关的关系。
在下面的表2中分别给出了在第三指节和第二指节测量血压数据的准确度评估结果。
表2
其中MD表示中位数差(Median Deviation，MD)，SD表示标准差(Standard Deviation，SD)。
从表2中可以看到在第三指节和第二指节测量血压数据的准确度评估结果。具体来看，收缩压SBP的中位数差SBP_MD和舒张压DBP的中位数差DBP_MD的绝对值都小于5，以及收缩压SBP的标准差SBP_SD和舒张压DBP标准差DBP_SD的绝对值都小于8，符合ISO医疗标准。
通过本申请实施例提供的所述生物特征信息检测装置20在第三指节和第二指节测量血压，得到的血压数据准确度均符合标准。
图9是本申请实施例提供的一种电子设备的结构框图。
如图9所示，本申请实施例还提供一种电子设备40，所述电子设备40包括上述本申请实施例提供的所述生物特征信息检测装置20，以及显示屏30，所述显示屏30设置在所述装置20的外表面，所述显示屏30用于显示所述生物特征信息。
具体的，所述显示屏30显示的所述生物特征信息包括血压值、血氧值和心率值。所述显示屏30可以单独显示血压值，也可以同时显示血压值、血氧值和心率值。
可选的，所述可穿戴设备还包括智能戒指，指夹式血压测量仪，指夹式血压血氧测量仪，指夹式多参数测量仪等可以应用在手指上的便携式血压测量设备。
图10是本申请实施例提供的一种电子设备的示意图。
如图10所示，所述电子设备40是一个多功能的指夹式血压血氧测量仪，可以测量的生物特征信息包括：心率值、血氧值、心率变异性(HRV)和血压值等。
本申请实施例中的所述电子设备40，可以方便高血压用户在非居家环境下快速便捷的监测实时血压，提升用户体验。
以上结合附图详细描述了本申请的优选实施方式，但是，本申请并不限于上述实施方式中的具体细节，在本申请的技术构思范围内，可以对本申请的技术方案进行多种简单变型，这些简单变型均属于本申请的保护范围。

Claims (12)

  1. 一种生物特征信息检测装置，所述装置包括：
    手指套，所述手指套包括机械结构或气囊，所述机械结构或所述气囊用于将所述手指套固定在用户的手指上；
    脉搏波传感器，所述脉搏波传感器包括光发射器和光电二极管，所述光发射器用于发射光信号，所述光信号被待检测物体反射或透射后到达所述光电二极管，所述光电二极管用于将接收到的光信号转换成电信号；
    模拟前端，所述模拟前端与所述脉搏波传感器电连接，且所述模拟前端用于接收所述电信号，并输出模拟前端信号；
    微控制单元，所述微控制单元与所述模拟前端电连接，且所述微控制单元用于接收所述模拟前端信号，并输出生物特征信息，所述生物特征信息包括血压值。
  2. 如权利要求1所述的装置，所述装置还包括压力检测器，所述压力检测器与所述模拟前端电连接。
  3. 如权利要求1或2所述的装置，所述手指套为两端贯通型手指套，所述两端贯通型手指套的横截面为环形。
  4. 如权利要求1或2所述的装置，所述手指套为非贯通型；
    所述非贯通型手指套仅在一端设置有开口；
    所述非贯通型手指套的截面为矩形、圆形、椭圆形和多边形中的一种，且所述非贯通型手指套具有内部空间，所述内部空间用于容纳所述用户的手指。
  5. 如权利要求3所述的装置，所述手指套还包括空气导管，所述空气导管和所述气囊连接。
  6. 如权利要求4所述的装置，所述机械结构包括弹簧结构，所述弹簧结构包括弹簧本体和连接板；
    所述连接板和所述弹簧本体的一端连接，所述弹簧本体的另一端和所述手指套连接，且所述弹簧结构设置在所述手指套内部靠近所述开口的一侧。
  7. 如权利要求6所述的装置，所述弹簧本体包括第一弹簧本体和第二弹簧本体，所述连接板包括第一连接板和第二连接板；
    所述第一连接板和所述第一弹簧本体连接，所述第二连接板和所述第二 弹簧本体连接，所述第一连接板上设置有所述光发射器，所述第二连接板上设置有所述光电二极管。
  8. 如权利要求4所述的装置，所述机械结构或所述气囊设置在所述手指套内部靠近所述开口的一侧。
  9. 如权利要求4所述的装置，所述机械结构包括电机结构，所述电机结构包括电机和连接板，所述连接板和所述电机连接，所述电机用于控制所述连接板活动，且所述电机结构设置在所述手指套内部靠近所述开口的一侧。
  10. 如权利要求1所述的装置，所述生物特征信息还包括心率值和血氧值中的至少一个。
  11. 一种电子设备，所述电子设备包括如权利要求1至10中任一项所述的装置，以及显示屏，所述显示屏设置在所述装置的外表面，所述显示屏用于显示所述生物特征信息。
  12. 如权利要求11所述的电子设备，所述电子设备包括智能戒指，指夹式血压测量仪，指夹式血压血氧测量仪，指夹式多参数测量仪。
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