WO2025005478A1 - Implant oculaire - Google Patents

Implant oculaire Download PDF

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Publication number
WO2025005478A1
WO2025005478A1 PCT/KR2024/006877 KR2024006877W WO2025005478A1 WO 2025005478 A1 WO2025005478 A1 WO 2025005478A1 KR 2024006877 W KR2024006877 W KR 2024006877W WO 2025005478 A1 WO2025005478 A1 WO 2025005478A1
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WO
WIPO (PCT)
Prior art keywords
annular edge
ocular implant
inner annular
pupil
relatively
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/KR2024/006877
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English (en)
Korean (ko)
Inventor
이동호
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beaueyevision Co Ltd
Original Assignee
Beaueyevision Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1020240028125A external-priority patent/KR20250000849A/ko
Application filed by Beaueyevision Co Ltd filed Critical Beaueyevision Co Ltd
Priority to CN202480029467.0A priority Critical patent/CN121038751A/zh
Publication of WO2025005478A1 publication Critical patent/WO2025005478A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/16—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for measuring intraocular pressure, e.g. tonometers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/04—Metals or alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds

Definitions

  • the present invention relates to an ocular implant.
  • Circle lenses which are plastic lenses intended to enlarge the appearance of the pupil, are formed by inserting a dye between two different lenses, and, compared to contact lenses for vision correction, have problems such as reduced oxygen permeability and an uneven surface.
  • the contact area and opportunity of bacteria and the circle lens increase, which may cause side effects such as neovascularization, keratitis, corneal ulcers, and corneal edema.
  • neovascularization may reduce the appearance of the pupil, which is contrary to the plastic purpose of circle lenses, which is to enlarge the appearance of the pupil
  • corneal hypoxia may cause a side effect in which neovascularization causes the peripheral cornea to turn white and opaque.
  • One embodiment of the present invention comprises an ocular implant that is permanently implanted on an eyeball without the hassle of attachment/detachment, and that can form a beautiful appearance integrated with the pupil without blocking an entrance aperture of light.
  • One embodiment of the present invention includes an ocular implant that adheres closely to a discontinuous edge of an eyeball, thereby minimizing side effects while improving handling convenience.
  • One embodiment of the present invention comprises an ocular implant that can be adaptively deformed into a shape optimized for the shape and size of the pupil of each recipient of the ocular implant, while reducing manufacturing costs through a single design mold to provide versatility.
  • One embodiment of the present invention includes an ocular implant in which the convenience of the procedure of the ocular implant is improved while side effects resulting from a structure that takes the convenience of the procedure into consideration are blocked.
  • An ocular implant that is permanently implanted on the recipient's eye to provide an enlarged appearance to the recipient's pupil
  • It may include a pupil expansion portion formed with a variable thickness that changes from the inner annular edge to the outer annular edge between the inner annular edge and the outer annular edge.
  • An ocular implant that is permanently implanted on the recipient's eye to provide an enlarged appearance to the recipient's pupil
  • It may include an adaptive elastic member that adaptively provides length expansion along at least one of the inner annular edge and the outer annular edge.
  • An ocular implant that is permanently implanted on the recipient's eye to provide an enlarged appearance to the recipient's pupil
  • It may include a pupil expansion portion formed between the inner annular edge and the outer annular edge, including first and second ends separated from each other through an incision and joined toward each other through a surgical hole formed in each.
  • An ocular implant that is permanently implanted on the recipient's eye to provide an enlarged appearance to the recipient's pupil
  • It may include a pupil expansion portion formed between the inner annular edge and the outer annular edge, and including first and second ends separated from each other through the cut portion and forming a catch joint or hook joint with respect to each other.
  • an ocular implant can be provided that is permanently implanted on the eyeball without the hassle of attachment/detachment, and that can form a beautiful appearance integrated with the pupil without blocking the light entrance aperture.
  • the present invention it is possible to provide an ocular implant that adheres closely to a discontinuous edge of the eyeball, thereby minimizing side effects and improving handling convenience.
  • an ocular implant can be provided that can be adaptively transformed into a shape optimized for the shape and size of the pupil of each recipient while reducing the manufacturing cost through a single design mold to provide versatility.
  • an ocular implant in which the convenience of the procedure of the ocular implant is improved, while side effects resulting from a structure that takes the convenience of the procedure into consideration are prevented.
  • FIG. 1 is a drawing illustrating a schematic structure of an eye into which an ocular implant according to one embodiment of the present invention is permanently implanted.
  • FIG. 2 is a drawing for explaining a procedure for an ocular implant according to one embodiment of the present invention, showing an incision formed at a certain location along the outer ring of the pupil.
  • FIG. 3 is a perspective view of an ocular implant according to one embodiment of the present invention.
  • FIG. 4 is a plan view illustrating the ocular implant illustrated in FIG. 3 from a frontal direction.
  • Figure 5 shows a cross-sectional view taken along line V-V ⁇ of Figure 3.
  • FIG. 6 is a perspective view illustrating an adaptive elastic member applied to an ocular implant according to one embodiment of the present invention.
  • FIG. 7 is a perspective view for explaining an adaptive elastic member applied to an ocular implant according to one embodiment of the present invention, and is a perspective view for explaining a modified example of FIG. 6.
  • FIGS. 8A and 8B are cross-sectional views of an ocular implant taken along the circumferential direction of the pupillary dilatation portion, illustrating cross-sectional views for explaining different roughness processing surfaces having isotropic rotational resistance and anisotropic rotational resistance, respectively.
  • FIG. 9 is a drawing for explaining a surgical hole applied to an ocular implant according to one embodiment of the present invention, and is a plan view of the ocular implant as viewed from the front.
  • FIGS. 10A to 10C are perspective views of different ocular implants, illustrating the engagement of the first and second slits with the catch or the hook, applied to the ocular implants according to different embodiments of the present invention.
  • FIGS. 11A and 11B illustrate different drawings for explaining the engagement of a catch or hook of an assembly slit and an assembly ball applied to an ocular implant according to one embodiment of the present invention.
  • FIG. 12 is a drawing showing a modified embodiment of the ocular implant illustrated in FIG. 4.
  • FIG. 13 is a drawing showing a modified embodiment of the ocular implant illustrated in FIG. 6.
  • FIG. 14 is a drawing illustrating a configuration in which different mechanisms are combined to bind first and second ends separated from each other through a cut portion toward each other in one embodiment of the present invention.
  • FIG. 15 is a drawing showing a modified embodiment of the ocular implant illustrated in FIG. 9.
  • An ocular implant that is permanently implanted on the recipient's eye to provide an enlarged appearance to the recipient's pupil
  • It may include a pupil expansion portion formed with a variable thickness that changes from the inner annular edge to the outer annular edge between the inner annular edge and the outer annular edge.
  • the inner annular edge and the outer annular edge may surround the opening along different shapes.
  • the inner annular edge is formed in an oval shape following the shape of the pupil so as not to obscure the pupil (or pupil) forming the light entrance opening, but to provide an appearance integrated with the pupil, and surrounds the outer ring of the pupil at an adjacent position,
  • the above outer annular edge may be formed into a circle to provide an attractive circular appearance.
  • the inner annular edge is formed into an oval shape having different major and minor axis lengths
  • the above longitudinal length is formed along the direction in which a pair of eyes of the transplanter face each other,
  • the above-mentioned short-axis length can be formed along a direction perpendicular to the above-mentioned long-axis length.
  • the pupil expansion portion between the inner annular edge and the outer annular edge is formed such that one of the two positions along the short axis of the inner annular edge has a wider width than the other position.
  • the oval of the inner annular edge may be formed at a biased position that is offset from the other end within the circular shape of the outer annular edge.
  • a posterior slope positioned toward the eyeball so as to adhere closely to the eyeball
  • It may include an anterior surface that is positioned toward the outside world, opposite the eyeball;
  • the inner annular edge and the outer annular edge, which form the front of the eyeball, are observed as oval and circular, respectively, along the frontal direction from the front of the eyeball toward the back of the eyeball, where the crystalline lens performing the lens function and the pupil (or pupil) forming the light entrance opening are placed.
  • the above rear inclined surface can be formed as a surface inclined at a constant tilting angle from a vertical plane perpendicular to the front direction so that the inner annular edge and the outer annular edge form a forward position and a rearward position, respectively.
  • the posterior slope may provide a support surface that supports on an inclined surface formed on the packaging container of the ocular implant.
  • the front curved surface may be formed along a spline curve in which the curvature or radius of curvature changes along the slope direction of the rear sloped surface.
  • the pupillary expansion member may have a variable thickness, where the thickness between the posterior slope and the anterior curve is variable.
  • the thickness of the pupillary dilatation portion can be measured along a direction perpendicular to the posterior slope from the posterior slope to the anterior curve.
  • the inner annular edge may be formed such that the anterior curved surface and the posterior sloped surface, which form the thickness of the pupillary expansion portion, are in contact with each other at a location where they contact the opening.
  • the outer annular edge may be formed such that the anterior curved surface and the posterior sloped surface, which form the thickness of the pupillary expansion portion, abut against each other on opposite sides of the inner annular edge, which defines the opening.
  • the front curved surface and the rear inclined surface forming the thickness of the pupil expansion portion may abut against each other while forming an inner annular edge and an outer annular edge of a rounded corner shape, respectively.
  • the inner annular edge is formed into a relatively gently rounded corner shape
  • the above outer annular edge can be formed into a relatively sharply rounded corner shape.
  • the thickness of the edge of the inner annular edge may be formed thinner than the thickness of the edge of the outer annular edge.
  • the inner annular edge extending from the cornea which is a convex portion protruding toward the front among the membrane tissues that entirely surround the eyeball to maintain the shape of the eyeball, to the discontinuous edge between the sclera, which is a small curvature portion extending posteriorly from the cornea, can be finished on one side of the ocular implant with a relatively gently rounded corner shape.
  • the outer annular edge that adheres closely to the cornea of the above-mentioned large curvature portion can be finished on the other side of the ocular implant with a relatively sharply rounded corner shape so as not to lift off from the cornea or to prevent a gap from being formed between the cornea and the implant.
  • the above pupil expansion portion has a maximum thickness portion having a maximum thickness between the inner annular edge and the outer annular edge;
  • It may be formed relatively far from the above opening and may include an outer portion between the maximum thickness portion and the outer annular edge.
  • the inner and outer parts arranged on either side based on the maximum thickness part may have an asymmetrical shape or an asymmetrical thickness profile.
  • the inner portion is formed relatively softly so as to adaptively deform to the pupil of each transplant recipient.
  • the outer portion may be formed to be relatively rigid so as to maintain a neat circular appearance against deformation of the inner portion and to reinforce the ductility of the inner portion to provide supporting rigidity of the ocular implant.
  • the inner portion may be formed with a thinner thickness than the outer portion so that it is inserted into the discontinuous edge between the cornea, which is a large curvature portion that protrudes convexly toward the front among the membrane tissues that entirely surround the eyeball to maintain the shape of the eyeball, and the sclera, which is a small curvature portion that extends posteriorly from the cornea, and adheres closely to the discontinuous edge without forming a gap between the discontinuous edge and the inner portion.
  • the inner and outer parts are formed of the same material
  • the thickness of the inner portion can be formed relatively thinner than the thickness of the outer portion.
  • the pupil expansion portion includes a front curved surface and a rear inclined surface forming the thickness of the pupil expansion portion
  • the first average thickness of the inner portion formed by the rear inclined surface and the front curved surface and the second average thickness of the outer portion can be formed such that the first average thickness ⁇ the second average thickness.
  • the front curved surface forming the inner portion may extend along a trajectory that is relatively close to the rear inclined surface, and the front curved surface forming the outer portion may extend along a trajectory that is relatively far from the rear inclined surface, thereby forming a difference in thickness between the inner portion and the outer portion formed on both sides based on the maximum thickness portion.
  • the front curve forming the inner portion forms a relatively thin thickness while extending along a relatively adjacent trajectory to the rear inclined surface, and then forms a gently rounded corner at the inner annular edge while following a relatively gentle downward curve toward the rear inclined surface.
  • the front curve forming the above outer portion can form a relatively thick thickness while extending along a relatively distant trajectory with respect to the rear inclined surface, and then form a sharply rounded corner at the outer annular edge while following a relatively steep downward curve toward the rear inclined surface.
  • the front curve forming the inner portion follows a downward curve from the maximum thickness portion toward the inner annular edge, and then follows a more steep downward curve through the inner inflection point to form a gently rounded inner annular edge so as to finish one side of the ocular implant.
  • the front curve forming the outer portion can form a sharply rounded outer annular edge by following a downward curve from the maximum thickness portion toward the outer annular edge and then following a more steep downward curve through the outer inflection point to finish the other side of the ocular implant.
  • the distance from the outer annular edge to the outer inflection point may be formed to be relatively longer than the distance from the inner annular edge to the inner inflection point.
  • the inner and outer inflection points may form points with the greatest change in curvature along the profile of the front surface forming the inner and outer portions, respectively.
  • An ocular implant that is permanently implanted on the recipient's eye to provide an enlarged appearance to the recipient's pupil
  • It may include an adaptive elastic member that adaptively provides length expansion along at least one of the perimeter of the inner annular edge and the perimeter of the outer annular edge.
  • the adaptive elastic member may provide longitudinal elasticity along the perimeter of the inner annular edge to adaptively deform to the shape and size of the pupil of each recipient.
  • the inner annular edge is formed into an oval shape having different major and minor axis lengths
  • the adaptive elastic member may provide a length extension along the major axis direction and/or the minor axis direction to adaptively provide an inner annular edge of a slip-shaped ellipse with a relatively long axis length extension and/or a short axis length extension and a root-shaped ellipse with a relatively short axis length extension and/or a short axis length extension to suit the pupil of the recipient.
  • the adaptive elastic member may include at least one slit formed around the perimeter of the inner annular edge.
  • the adaptive elastic member may include a plurality of slits formed spaced apart from one another along the perimeter of the inner annular edge.
  • the plurality of slits may be formed spaced apart from one another at even intervals along the perimeter of the inner annular edge.
  • the adaptive elastic member may include a group of slits formed at opposite positions along the longitudinal direction and/or at opposite positions along the short-axis direction.
  • the adaptive elastic member For example, the adaptive elastic member, the adaptive elastic member, the adaptive elastic member, and
  • the pieces divided into the first and second groups are overlapped with each other through the slits formed at both sides along the above-mentioned shortened direction, thereby shortening the long-axis length while extending the short-axis length.
  • the pieces divided into the third and fourth groups formed at opposite positions along the longitudinal direction can be overlapped to extend the longitudinal length and shorten the short-axis length.
  • the slits can be formed at positions spaced apart by a constant angle about the center of the opening where the major axis and the minor axis of the inner annular edge intersect each other as the center of rotation.
  • It may include third and fourth groups of slits formed at 90 degree angle positions and 270 degree angle positions corresponding to both sides along the longitudinal direction.
  • the slit may extend into the interior of the pupillary dilatation portion along a depth direction from the inner annular edge toward the outer annular edge.
  • the slit can be introduced into the interior of the pupil dilatation section in a radial direction in the depth direction from the center of the opening where the major axis length and the minor axis length intersect.
  • the adaptive elastic member may be configured to stretch the length of the inner annular edge by overlapping the pieces separated from each other through the slits along the perimeter of the inner annular edge.
  • a posterior slope positioned toward the eyeball so as to adhere closely to the eyeball
  • a front curved surface is disposed toward the outside opposite to the eyeball and forms a thickness profile based on the rear slope, such that an inner annular edge is formed while contacting the rear slope at a position in contact with the opening, an outer annular edge is formed while contacting the rear slope at a position opposite to the opening, and a maximum thickness portion forming a maximum thickness between the inner annular edge and the outer annular edge is formed, such that a relatively thin inner portion and a relatively thick outer portion are formed based on the rear slope,
  • the pieces divided through the slits forming the above adaptive elastic portion can be overlapped with each other to increase the thickness of the inner portion where the slits introduced from the inner annular edge are formed while stretching the length of the inner annular edge, thereby forming extra thickness.
  • the adaptive elastic portion is formed on the inner annular edge surrounding the outer ring of the pupil at a position relatively closer to the outer annular edge so as to adaptively deform to the shape and size of the pupil of each transplant recipient.
  • the outer annular edge may not be formed.
  • the inner annular edge where the pieces divided through the slit forming the adaptive elastic portion are arranged to overlap each other, is formed in a relatively gently rounded corner shape
  • the above outer annular edge can be formed into a relatively sharply rounded corner shape.
  • An ocular implant that is permanently implanted on the recipient's eye to provide an enlarged appearance to the recipient's pupil
  • It may include a pupil expansion portion formed between the inner annular edge and the outer annular edge, including first and second ends separated from each other through an incision and joined toward each other through a surgical hole formed in each.
  • the oval of the inner annular edge is formed inside the circle of the outer annular edge so that the positions on both sides along the short axis of the inner annular edge are formed with a relatively wider width than the positions on both sides along the long axis of the inner annular edge.
  • the above-mentioned incision, the first and second ends separated from each other through the above-mentioned incision, and the surgical hole formed on the first and second ends can be formed at any one of the two positions along the short-axis direction formed with a relatively wide width.
  • the positions on both sides along the short axis direction of the inner annular edge are formed with a relatively smaller curvature than the positions on both sides along the long axis direction of the inner annular edge.
  • the above-mentioned surgical hole can be formed at either one of the two positions along the short-axis direction formed with a relatively small curvature.
  • the cut is formed along the short axis direction of the inner annular edge
  • the first and second ends separated from each other through the above-mentioned cutting portion are joined to each other along the longitudinal direction of the inner annular edge
  • Each of the first and second ends may have a plurality of surgical holes formed along the longitudinal direction of the inner annular edge.
  • the ocular implant may include a second surgical hole through which an implantation insertion device passes to tract the ocular implant so that the ocular implant can be guided along the outer ring of the surgeon's pupil through an incision in the conjunctiva on the cornea.
  • the first treatment hole is formed with a relatively small diameter
  • the above second treatment hole can be formed with a relatively large diameter.
  • the first surgical hole is formed at a location relatively close to the incision
  • the above second surgical hole can be formed at a location relatively far from the incision site.
  • An ocular implant that is permanently implanted on the recipient's eye to provide an enlarged appearance to the recipient's pupil
  • It may include a pupil expansion portion formed between the inner annular edge and the outer annular edge, and including first and second ends separated from each other through the cut portion and forming a catch joint or hook joint with respect to each other.
  • the oval of the inner annular edge is formed inside the circle of the outer annular edge so that the positions on both sides along the short axis of the inner annular edge are formed with a relatively wider width than the positions on both sides along the long axis of the inner annular edge.
  • the above-mentioned cut portion, the first and second ends separated from each other through the above-mentioned cut portion, and the catch joint or hook joint between the first and second ends can be formed at any one of the two positions along the short-axis direction formed with a relatively wide width.
  • It may include first and second slits formed on the first and second ends, respectively.
  • first and second slits may be formed in complementary shapes to form a catch-joint or hook-joint with each other and may be fitted into each other.
  • It may include a second portion extending from the first portion toward the inner annular edge or the outer annular edge along a diagonal direction that simultaneously follows the short-axis direction of the inner annular edge or the short-axis direction and the long-axis direction, and opening to the outside of the ocular implant;
  • the first part of the first and second slits extends parallel to the longitudinal direction of the inner annular edge
  • the second portions of the first and second slits may be formed in complementary shapes, such that one of the first and second slits and the second portion of the other slit may extend in opposite directions toward the outer annular edge and the inner annular edge, respectively, and may be opened toward the exterior of the ocular implant.
  • the incision is formed along the short axis direction of the inner annular edge
  • first and second ends are adjacent to each other along the longitudinal direction of the inner annular edge
  • one of the slits may include an array of slits formed in multiple numbers on the first end or the second end along the longitudinal direction, and the remaining other slits may be formed as a single slit.
  • It may include an assembly hole formed in the second end and into which the assembly slit is fitted.
  • an assembly guide portion may be formed on the first end portion and positioned in a forward position of the assembly slit along the assembly direction between the first and second ends.
  • It includes a protrusion of the front end formed with a relatively narrow width at the front end of the first end along the assembly direction of the first and second ends, and a rear end formed with a relatively wider width than the bottleneck of the assembly slit while being located behind the protrusion of the front end and in front of the assembly slit.
  • variable width portion may further include a shape that converges toward the protrusion along a diagonal direction that simultaneously follows the major axis direction corresponding to the assembly direction and the minor axis direction intersecting the major axis direction to connect the protrusion of the front end formed with a relatively narrow width and the protrusion of the rear end formed with a relatively wide width with differential widths.
  • the rear end of the assembly induction member may be connected to the full width of the first end interposed between the assembly induction member and the assembly slit.
  • a cut line including an array of perforations formed in a plurality may be formed between the assembly guide portion and the full width of the first end portion.
  • the assembly slit is introduced from the inner annular edge and the outer annular edge on both sides along the shortened direction of the inner annular edge to form a bottleneck of minimum width
  • the separation between the first and second ends can be prevented through the relatively wide width of the first end formed before and after the assembly slit.
  • FIG. 1 is a drawing illustrating a schematic structure of an eye into which an ocular implant according to one embodiment of the present invention is permanently implanted.
  • FIG. 2 is a drawing for explaining a procedure for an ocular implant according to one embodiment of the present invention, and illustrates an incision formed at a certain location along the outer ring of the pupil.
  • FIG. 3 is a perspective view of an ocular implant according to one embodiment of the present invention.
  • FIG. 4 is a plan view illustrating the ocular implant illustrated in FIG. 3 from a frontal direction.
  • Figure 5 shows a cross-sectional view taken along line V-V ⁇ of Figure 3.
  • FIG. 6 is a perspective view illustrating an adaptive elastic member applied to an ocular implant according to one embodiment of the present invention.
  • FIG. 7 is a perspective view for explaining an adaptive elastic member applied to an ocular implant according to one embodiment of the present invention, and is a perspective view for explaining a modified example of FIG. 6.
  • FIGS. 8A and 8B are cross-sectional views of an ocular implant taken along the circumferential direction of the pupillary dilatation portion, illustrating cross-sectional views for explaining different roughness processing surfaces having isotropic rotational resistance and anisotropic rotational resistance, respectively.
  • FIG. 9 is a drawing for explaining a surgical hole applied to an ocular implant according to one embodiment of the present invention, and is a plan view of the ocular implant as viewed from the front.
  • FIGS. 10A to 10C are perspective views of different ocular implants, illustrating the engagement of the first and second slits with the catch or the hook, applied to the ocular implants according to different embodiments of the present invention.
  • FIGS. 11A and 11B illustrate different drawings for explaining the engagement of a catch or hook of an assembly slit and an assembly ball applied to an ocular implant according to one embodiment of the present invention.
  • an ocular implant (100) including a pupil expansion portion (105) formed with variable thickness between an inner annular edge (101) and an outer annular edge (102), a shape of a front curved surface (120) forming a profile with variable thickness on a rear slope (110) of the pupil expansion portion (105), and circular and elliptical profiles formed by the inner annular edge (101) and the outer annular edge (102), respectively.
  • FIG. 1 is a drawing illustrating a schematic structure of an eye into which an ocular implant according to one embodiment of the present invention is permanently implanted.
  • FIG. 2 is a drawing for explaining a procedure for an ocular implant according to one embodiment of the present invention, and illustrates an incision formed at a certain location along the outer ring of the pupil.
  • FIG. 3 is a perspective view of an ocular implant according to one embodiment of the present invention.
  • FIG. 4 is a plan view illustrating the ocular implant illustrated in FIG. 3 from a frontal direction.
  • Figure 5 shows a cross-sectional view taken along line V-V ⁇ of Figure 3.
  • An ocular implant (100) according to one embodiment of the present invention is
  • It may include a pupil expansion portion (105) formed with a variable thickness that changes from the inner annular edge (101) to the outer annular edge (102) between the inner annular edge (101) and the outer annular edge (102).
  • the inner annular edge (101) and the outer annular edge (102) may surround the opening (OP) along different shapes.
  • the inner annular edge (101) is formed in an oval shape along the shape of the pupil so as not to cover the pupil (or pupil) forming the light entrance opening, but to provide an appearance integrated with the pupil, and surrounds the outer ring of the pupil at an adjacent position.
  • the above outer annular edge (102) may be formed into a circle to provide an attractive circular appearance.
  • the inner annular edge (101) is formed in an oval shape having different major axis lengths (L1) and minor axis lengths (L2).
  • the above longitudinal length (L1) is formed along the direction in which a pair of eyes of the transplanter face each other,
  • the above-mentioned short-axis length (L2) can be formed along a direction perpendicular to the above-mentioned long-axis length (L1).
  • the pupil expansion portion (105) between the inner annular edge (101) and the outer annular edge (102) is formed so that one of the two positions along the short axis direction (Z2) of the inner annular edge (101) has a wider width than the other position.
  • the oval shape of the inner annular edge (101) within the circular shape of the outer annular edge (102) may be formed at a biased position that is offset from the other side.
  • the pupil expansion part (105) is the pupil expansion part (105)
  • a rear inclined surface (110) positioned toward the eyeball (EB) so as to adhere closely to the eyeball (EB);
  • It may include a front curve (120) positioned toward the outer world (OS) opposite to the eyeball (EB).
  • OS outer world
  • EB eyeball
  • the inner annular edge (101) and the outer annular edge (102) form the front of the eyeball (EB), respectively, and are observed as oval and circular in the frontal direction (Z3) from the front of the eyeball (EB) toward the back of the eyeball (EB) where the crystalline lens performing the lens function and the pupil (or pupil) forming the light entrance opening are arranged.
  • the above rear inclined surface (110) can be formed as a surface inclined at a constant tilting angle ( ⁇ ) from a vertical plane (G) perpendicular to the front direction (Z3) so that the inner annular edge (101) and the outer annular edge (102) form a forward position and a rearward position, respectively.
  • the rear slope (110) can provide a support surface supported on an inclined surface formed on the packaging container of the ocular implant (100).
  • the front curved surface (120) may be formed along a spline curve in which the curvature or radius of curvature changes along the inclination direction of the rear inclined surface (110).
  • the pupil expansion portion (105) may have a variable thickness that varies from the rear slope (110) to the front curved surface (120).
  • the thickness of the pupil expansion portion (105) may be measured along a direction perpendicular to the rear slope (110) from the rear slope (110) to the front curved surface (120).
  • the inner annular edge (101) may be formed by the front curved surface (120) and the rear inclined surface (110) forming the thickness of the pupil expansion portion (105) contacting each other at a position where they are in contact with the opening (OP).
  • the outer annular edge (102) may be formed such that the front curved surface (120) and the rear inclined surface (110), which form the thickness of the pupil expansion portion (105), contact each other on opposite sides of the inner annular edge (101) that defines the opening (OP).
  • the front curved surface (120) and the rear inclined surface (110) forming the thickness of the pupil expansion portion (105) may contact each other while forming an inner annular edge (101) and an outer annular edge (102) of a rounded corner shape, respectively.
  • the inner annular edge (101) may be formed as a relatively gently rounded corner shape
  • the outer annular edge (102) may be formed as a relatively sharply rounded corner shape.
  • the thickness of the edge of the inner annular edge (101) may be formed thinner than the thickness of the edge of the outer annular edge (102).
  • the inner annular edge (101) that extends to the discontinuous edge (DE) between the cornea in the large curvature portion that protrudes convexly toward the front and the sclera in the small curvature portion extending posteriorly from the cornea among the membrane tissues that entirely surround the eyeball (EB) to maintain the shape of the eyeball (EB) can be finished on one side of the ocular implant (100) with a relatively gently rounded corner shape.
  • the outer annular edge (102) that adheres closely to the cornea of the above-mentioned large curvature portion can be finished on the other side of the ocular implant (100) with a relatively sharply rounded corner shape so as not to lift off from the cornea or to prevent a gap from being formed between the cornea and the cornea.
  • the pupil expansion part (105) is the pupil expansion part (105)
  • a maximum thickness portion (t5) having a maximum thickness between the inner annular edge (101) and the outer annular edge (102);
  • It may include an outer portion (OA) formed relatively far from the above opening (OP) and between the maximum thickness portion (t5) and the outer annular edge (102).
  • the inner part (IA) and the outer part (OA) arranged on both sides based on the maximum thickness part (t5) may have an asymmetrical shape or an asymmetrical thickness profile.
  • the medial aspect (IA) is formed relatively ductile to adaptively deform to the pupil of each recipient.
  • the above outer portion (OA) can be formed to be relatively rigid so as to maintain a neat circular appearance against deformation of the inner portion (IA) and to reinforce the ductility of the inner portion (IA) to provide support rigidity of the ocular implant (100).
  • the inner portion (IA) may be formed with a thinner thickness than the outer portion (OA) so that it is introduced up to the discontinuous edge (DE) between the cornea, which is a large curvature portion that protrudes convexly toward the front among the membrane tissues that entirely surround the eyeball (EB) to maintain the shape of the eyeball (EB), and the sclera, which is a small curvature portion that extends posteriorly from the cornea, and adheres closely to the discontinuous edge (DE) without forming a gap between the discontinuous edge (DE).
  • DE discontinuous edge
  • the inner part (IA) and the outer part (OA) are formed of the same material,
  • the thickness of the inner portion (IA) can be formed relatively thinner than the thickness of the outer portion (OA).
  • the first average thickness of the inner portion (IA) formed by the rear slope (110) and the front curved surface (120) and the second average thickness of the outer portion (OA) can be formed as the first average thickness ⁇ the second average thickness.
  • the front curved surface (120) forming the inner portion (IA) extends along a trajectory that is relatively close to the rear inclined surface (110), and the front curved surface (120) forming the outer portion (OA) extends along a trajectory that is relatively far from the rear inclined surface (110), thereby forming a difference in thickness between the inner portion (IA) and the outer portion (OA) formed on both sides based on the maximum thickness portion (t5).
  • the front curved surface (120) forming the inner portion (IA) forms a relatively thin thickness while extending along a relatively adjacent trajectory to the rear inclined surface (110), and then forms a gently rounded corner at the inner annular edge (101) while following a relatively gentle downward curve toward the rear inclined surface (110).
  • the front curved surface (120) forming the above outer portion (OA) may form a relatively thick thickness while extending along a relatively distant trajectory with respect to the rear inclined surface (110) and then form a sharply rounded corner at the outer annular edge (102) while following a relatively steep downward curve toward the rear inclined surface (110).
  • the front curve (120) forming the inner portion (IA) follows a downward curve from the maximum thickness portion (t5) toward the inner annular edge (101) and then forms a gently rounded inner annular edge (101) while following a more steep downward curve through the inner inflection point (101 ⁇ ) to finish one side of the ocular implant (100).
  • the front curve (120) forming the outer portion (OA) can form a sharply rounded outer annular edge (102) by following a downward curve from the maximum thickness portion (t5) toward the outer annular edge (102) and then following a more steep downward curve through the outer inflection point (102 ⁇ ) to finish the other side of the ocular implant (100).
  • the distance from the outer annular edge (102) to the outer inflection point (102 ⁇ ) may be formed to be relatively longer than the distance from the inner annular edge (101) to the inner inflection point (101 ⁇ ).
  • the inner inflection point (101 ⁇ ) and the outer inflection point (102 ⁇ ) may form points at which the curvature change is the greatest along the profile of the front curved surface (120) forming the inner portion (IA) and the outer portion (OA), respectively.
  • the ocular implant (100) of the present invention may be provided as a roughly ring-shaped member having an opening (OP) formed in the center so that light may be incident toward the crystalline lens (or pupil) that performs the lens function of the eyeball (EB) or the pupil that forms the opening of the eyeball (EB).
  • OP opening
  • EB crystalline lens
  • EB lens function of the eyeball
  • EB pupil
  • the above ocular implant (100) can be formed as a ring-shaped member that surrounds the outer ring of the pupil of the implant recipient to enlarge the size of the pupil, and has an opening (OP) formed in the center to allow light to enter the pupil while surrounding the outer ring of the pupil of the implant recipient.
  • OP opening
  • the ocular implant (100) may include an inner annular edge (101) surrounding the outer ring of the pupil of the implant recipient, an outer annular edge (102) surrounding the outer ring of the pupil together with the inner annular edge (101) on the opposite side of the inner annular edge (101), and a pupil expansion portion (105) formed between the inner annular edge (101) and the outer annular edge (102) with a variable thickness that changes from the inner annular edge (101) to the outer annular edge (102).
  • the above pupil expansion portion (105) may be defined between an inner annular edge (101) and an outer annular edge (102) that surround the pupil outer ring together at the inner and outer positions, respectively, and may provide an expansion area of the pupil in the ocular implant (100) according to one embodiment of the present invention.
  • the inner annular edge (101) and the outer annular edge (102) may define a shape of the pupil expansion portion (105) forming the ocular implant (100) or the body of the ocular implant (100), and may define at least a part of a shape of the ocular implant (100).
  • an ocular implant (100) can be formed into a three-dimensional shape so as to be closely attached to an approximately spherical eyeball (EB), and considering that a main function of the ocular implant (100) according to one embodiment of the present invention is to beautifully improve the shape of the pupil or iris observed in the frontal direction (Z3) of the recipient's face, and that the shape of the pupil or iris observed in the frontal direction (Z3) of the recipient's face can be defined by an inner annular edge (101) and an outer annular edge (102) defining a shape observed in the frontal direction (Z3) of the pupil dilatation portion (105), the shapes of the inner annular edge (101) and the outer annular edge (102) hereinafter may mean a two-dimensional line shape observed in the frontal direction (Z3) of the recipient's face.
  • EB approximately spherical eyeball
  • the ocular implant (100) since the ocular implant (100) according to one embodiment of the present invention is to be permanently implanted on the recipient's eyeball (EB), it can be formed into an appropriate three-dimensional shape so that it can adhere closely to the approximately spherical eyeball (EB), and for example, the cross-sectional shape of the pupil expansion portion (105) cut in the frontal direction (Z3) can be formed with a variable thickness that changes from the inner expansion edge to the outer expansion edge so that it can adhere closely to the approximately spherical eyeball (EB).
  • the pupil expansion portion (105) may be formed in a three-dimensional shape so as to be closely fitted onto an eyeball (EB) formed in a roughly spherical shape, and may include a posterior inclined surface (110) that is inclined at a constant tilting angle ( ⁇ ) from a vertical plane (G) perpendicular to the frontal direction (Z3) so as to be closely fitted onto the eyeball (EB), and a front curved surface (120) that is arranged toward the outside (OS) opposite to the eyeball (EB), in a cross-sectional shape cut along the frontal direction (Z3).
  • a posterior inclined surface (110) that is inclined at a constant tilting angle ( ⁇ ) from a vertical plane (G) perpendicular to the frontal direction (Z3) so as to be closely fitted onto the eyeball (EB), and a front curved surface (120) that is arranged toward the outside (OS) opposite to the eyeball (EB), in a cross-sectional shape cut along the frontal direction (Z3).
  • the eyeball (EB) is protected by a strong and tough membrane tissue that entirely surrounds the eyeball (EB), and the overall shape of the eyeball (EB) can be maintained, and the membrane tissue can include a cornea on the anterior side where light is incident, and a sclera extending posteriorly from the cornea.
  • the cornea can be formed at an anterior position of an anterior chamber formed in front of the pupil, a lens that performs the function of a lens and focuses the light on the retina at the posterior side of the eyeball (EB), and a pupil that forms an opening through which light is incident in front of the lens, and the lens, the pupil, and the anterior chamber can surround the anterior of the eyeball (EB) formed by these lens, the pupil, and the anterior chamber, and form a large curvature portion of the membrane tissue formed with a relatively large curvature.
  • the sclera extends posteriorly from the cornea, and can form a small curvature portion of the membrane tissue formed with a relatively small curvature.
  • the cornea and sclera respectively, surround the eyeball (EB) and form large and small curvatures that maintain the shape of the eyeball (EB), while also forming geometrical singularities such as discontinuous edges (DE) between them.
  • the cornea and the sclera can form large curvatures and small curvatures of the membrane tissue, respectively, which surround the entire eyeball (EB) and maintain the shape of the eyeball (EB), and substantially the same membrane tissue can be formed in a convex shape protruding toward the outside world (OS) opposite the eyeball (EB) while containing the lens, etc., at the anterior position, and the sclera extending posteriorly from the cornea at the anterior position can be formed with a reduced curvature compared to the cornea, and substantially formed in a shape closer to an inclined plane than a curved surface from the sclera beyond the discontinuous edge (DE) between the cornea and the sclera to the curved portion (AC) of the sclera.
  • OS outside world
  • AC discontinuous edge
  • An ocular implant (100) can be implanted on the sclera, for example, on the cornea positioned in front of the lens or the like, for example, on the sclera away from the cornea onto which light is incident, and in one embodiment of the present invention, the ocular implant (100) can be introduced forward to the discontinuous edge (DE) between the sclera and the cornea.
  • DE discontinuous edge
  • the cornea in the anterior position is formed with a relatively large curvature in the anterior position of the lens, etc.
  • the sclera extending posteriorly from the cornea is formed with a relatively small curvature, so that a discontinuous edge (DE) is formed between the cornea and the sclera, and the ocular implant (100) that can be introduced up to this discontinuous edge (DE) can accommodate the discontinuous edge (DE) between the cornea and the sclera and, so as not to form a gap between the tissue of the eyeball (EB) and the transplanted ocular implant (100), the inner part (IA) in contact with the opening (OP) can be formed with a relatively thinner thickness than the outer part (OA) that is relatively far from the opening (OP).
  • the pupil dilatation portion (105) may include a posterior slope (110) arranged toward the eyeball (EB) so as to be in close contact with the eyeball (EB), and an anterior curved surface (120) arranged toward the outer world (OS) opposite the eyeball (EB) so as to be opposite to the posterior slope (110), and may be formed with a variable thickness that changes between the posterior slope (110) and the anterior curved surface (120).
  • the thickness of the pupil dilatation portion (105) may correspond to a dimension along a direction perpendicular from the posterior slope (110) among the posterior slope (110) and the anterior curved surface (120) defining a portion of the pupil dilatation portion (105).
  • the pupil expansion portion (105) may be formed with a variable thickness that changes as it goes from the inner annular edge (101) to the outer annular edge (102), and more specifically, with the maximum thickness portion (t5) having the maximum thickness between the inner annular edge (101) and the outer annular edge (102) as a reference, the thickness may be gradually reduced as it goes to both sides of the inner annular edge (101) and the outer annular edge (102), so that both sides of the pupil expansion portion (105) may be finished at the inner annular edge (101) and the outer annular edge (102).
  • the thickness of the pupil expansion portion (105) can be defined along a direction perpendicular to the posterior slope (110) between the posterior slope (110) and the anterior curved surface (120), and the posterior slope (110) and the anterior curved surface (120) can contact each other at an inner annular edge (101) relatively in contact with the opening (OP) and an outer annular edge (102) far from the opening (OP), respectively, to form rounded corners at the inner annular edge (101) and the inner annular edge (101).
  • the front curved surface (120) can form a thickness profile of the pupil expansion portion (105) on the rear inclined surface (110), and can form a trajectory that is the farthest from the rear inclined surface (110) to form a maximum thickness portion (t5) between the inner annular edge (101) and the outer annular edge (102), and can form a downward trajectory gradually toward the rear inclined surface (110) while going to both sides of the maximum thickness portion (t5) to form the inner annular edge (101) and the outer annular edge (102) from both sides of the maximum thickness portion (t5), and can form the inner annular edge (101) and the outer annular edge (102) of rounded corners while coming into contact with the rear inclined surface (110).
  • the maximum thickness portion (t5) of the pupil expansion portion (105) may be formed at a central position between the inner annular edge (101) and the outer annular edge (102), and the pupil expansion portion (105) may include an inner portion (IA) between the maximum thickness portion (t5) and the inner annular edge (101), that is, an inner portion (IA) relatively adjacent to the central opening (OP), and an outer portion (OA) between the maximum thickness portion (t5) opposite to the inner portion (IA) and the outer annular edge (102), that is, an outer portion (OA) relatively far from the relatively central opening (OP).
  • the pupil dilatation part (105) may include an inner portion (IA) that is relatively close to the opening (OP) and an outer portion (OA) that is relatively far from the opening (OP), and may include the inner portion (IA) and the outer portion (OA) that have different thickness deviations.
  • the fact that the inner portion (IA) and the outer portion (OA) of the pupil dilatation part (105) have different thickness deviations may mean that, in one embodiment of the present invention, the pupil dilatation part (105) including the inner portion (IA) and the outer portion (OA) has an asymmetrical thickness profile or an asymmetrical shape based on the maximum thickness portion (t5) that forms the boundary between the inner portion (IA) and the outer portion (OA).
  • the front curved surface (120) forming the inner portion (IA) can form a trajectory that is relatively close to the rear inclined surface (110), and the front curved surface (120) forming the outer portion (OA) can form a trajectory that is relatively far from the rear inclined surface (110), while forming a difference in thickness between the inner portion (IA) and the outer portion (OA) formed on both sides based on the maximum thickness portion (t5) of the pupil dilation portion (105).
  • the fact that the inner part (IA) and the outer part (OA) of the pupil expansion part (105) have different thickness deviations may mean that, between the thickness integral of the inner part (IA) calculated along the slope direction over the entire length of the inner part (IA) from the rear inclined surface (110) to the front curved surface (120), which provides a thickness reference, and the thickness integral of the outer part (OA) calculated along the slope direction over the entire length of the outer part (OA) from the rear inclined surface (110) to the front curved surface (120), which provides a thickness reference, the thickness integral of the outer part (OA) has a relatively larger value than the thickness integral of the inner part (IA).
  • the thickness integral of the inner portion (IA) per unit length is obtained by dividing the thickness integral of the inner portion (IA) by the length of the inner portion (IA) following the slope direction and the thickness integral of the outer portion (OA) per unit length is obtained by dividing the thickness integral of the outer portion (OA) by the length of the outer portion (OA) following the slope direction
  • the thickness integral of the outer portion (OA) per unit length has a relatively larger value than the thickness integral of the inner portion (IA) per unit length.
  • the average thickness of the inner portion (IA) and the average thickness of the outer portion (OA) may mean the thickness integral of the inner portion (IA) per unit length and the thickness integral of the outer portion (OA) per unit length, respectively.
  • the pupil expansion portion (105) may form a maximum thickness portion (t5) at a central position between the inner annular edge (101) and the outer annular edge (102), while forming an inner portion (IA) and an outer portion (OA) having differential average thicknesses on both sides of the maximum thickness portion (t5), and at this time, the inner portion (IA) formed with a relatively low average thickness may be introduced to a discontinuous edge (DE) between the cornea of a large curvature portion formed in a convex shape protruding forward to include a lens, etc., among the sclera, and the sclera of a small curvature portion extending backward from the cornea, and by forming the average thickness of the inner portion (IA) introduced to the discontinuous edge (DE) relatively low, a gap is not formed between the discontinuous edge (DE) and the inner portion (IA) between the cornea and the sclera of the eyeball (EB).
  • a discontinuous edge (DE) between the cornea of a large curva
  • the average thickness can be formed relatively low.
  • the medial portion (IA) can be transplanted in a form inserted into a part of the eyeball (EB), and the medial portion (IA) can be inserted between the sclera and the conjunctiva through an incision (EBC) formed in the conjunctiva covering the sclera, and can be inserted to a discontinuous edge (DE) between the sclera and the cornea toward the front.
  • the medial portion (IA) can be formed with a relatively low average thickness compared to the outer portion (OA), and can be inserted into a narrow transplant space between the sclera and the conjunctiva secured through the procedure, and can be inserted to a sufficient depth to the discontinuous edge (DE) between the sclera and the cornea.
  • OA outer portion
  • DE discontinuous edge
  • a gap may be formed between the inner part (IA) and the discontinuous edge (DE) between the sclera and the cornea, and the gap between the inner part (IA) and the discontinuous edge (DE) that is not sufficiently adhered to the discontinuous edge (DE) of the eyeball (EB) may cause adverse effects such as bacteria or inflammation (e.g., corneal ulcer due to infection by bacteria, viruses, fungi, etc.).
  • the discontinuous edge (DE) between the sclera and the cornea and the inner side (IA) of the pupillary expansion portion (105) are not closely adhered to each other, the shape of the pupil or the pupil hole observed from the frontal direction (Z3) of the recipient's face may be distorted or dented, thereby failing to provide a pleasing appearance (causing cosmetic problems).
  • the inner side (IA) of the pupillary expansion portion (105) is not formed with a sufficiently thin thickness but is formed thick, a corneal ulcer may occur due to infection as tears do not sufficiently wet the cornea.
  • the outer portion (OA) can be formed with a relatively high average thickness compared to the inner portion (IA), and the outer portion (OA) can provide support rigidity of the entire ocular implant (100) through the relatively high average thickness.
  • the ocular implant (100) may be formed of a soft material, such as silicone, that is harmless to the human body and can flexibly adhere to the eyeball (EB). Even if formed of a soft material, considering ease of handling, such as production, packaging, and distribution, and ease of procedure for the procedure of the ocular implant (100), a certain degree of support rigidity may need to be secured.
  • the outer portion (OA) may be formed with a relatively high average thickness in consideration of the support rigidity of the entire ocular implant (100), unlike the inner portion (IA) that has a relatively low average thickness so as to be advantageous in adherence to the eyeball (EB) or a part of the tissue of the eyeball (EB).
  • the ocular implant (100) may be formed of a flexible, soft material, as it is permanently implanted on the eye (EB), but may include an inner part (IA) with relatively excellent softness and an outer part (OA) with relatively excellent rigidity through differences in shape while being formed of a single material.
  • IA inner part
  • OA outer part
  • the inner portion (IA) may be formed relatively ductile so as to be adaptively deformed to the pupil of each recipient, and the outer portion (OA) may be formed relatively rigidly so as to maintain a circular appearance prepared to counter deformation of the inner portion (IA) and to reinforce the ductility of the inner portion (IA) to provide support rigidity of the ocular implant (100).
  • the inner portion (IA) needs to adhere closely to a geometrical singularity, such as a discontinuous edge (DE) formed by the sclera and the cornea, and, for example, can be finely adjusted according to the size of the cornea so as to adhere as closely as possible to the cornea, and the inner portion (IA) can provide relatively excellent ductility and can be formed with a relatively low average thickness.
  • a geometrical singularity such as a discontinuous edge (DE) formed by the sclera and the cornea
  • the outer portion (OA) can be placed on the sclera with a relatively small curvature at a position relatively far from a geometric singularity, such as a discontinuous edge (DE) between the cornea and the sclera, for example, it can be placed on the sclera with a relatively small curvature closer to a slope than a curve from the sclera away from the discontinuous edge (DE) between the cornea and the sclera to the curvature (AC) of the sclera (less ductility for adhesion on the sclera is required), and in particular, it can be formed with a relatively high average thickness so as to supplement the rigidity of the inner portion (IA) with a relatively low average thickness and provide the supporting rigidity of the overall ocular implant (100).
  • a geometric singularity such as a discontinuous edge (DE) between the cornea and the sclera
  • the first average thickness of the inner portion (IA) formed by the posterior slope (110) and the anterior curved surface (120) and the second average thickness of the outer portion (OA) can satisfy a size relationship of the first average thickness ⁇ the second average thickness.
  • the opening (OP) may be formed in an open shape so as not to obstruct the incidence of light, for example, so as not to obstruct the incidence of light toward the pupil (or iris) providing the opening of the eyeball (EB), and the ductility of the inner part (IA) of the pupil dilatation part (105) may be increased through the opening (OP).
  • the inner part (IA) is preferably observed integrally with the pupil (or pupil) forming the opening of the eyeball (EB) for receiving light, while surrounding the outer ring of the pupil adjacent to the pupil so as not to cover the pupil, and in particular, considering the shape and size of the pupil which are different from each other depending on the physical condition of the recipient, sufficient flexibility can be provided so that the length can be adaptively expanded so as to surround the outer ring of each differential pupil, and for this purpose, in one embodiment of the present invention, unlike the comparative example which covers the central position with a transparent material so as not to obstruct the incidence of light, sufficient flexibility can be provided to the inner part (IA) through the opening (OP) at the central position which is in contact with the inner part (IA) so that it can be permanently transplanted in a manner customized to the physical condition of the recipient, for example, the shape and size of the pupil, without obstructing the incidence of light.
  • the inner portion (IA) may include an adaptive elastic portion (151) that can adaptively provide elasticity in length so that the pupils of different shapes and sizes can be surrounded by the outer ring of the pupils at the closest positions despite the individual physical conditions of each recipient, and this adaptive elastic portion (151) may be formed at a position adjacent to the inner portion (IA) of the pupil expansion portion (105), for example, the inner annular edge (101) forming the end of the inner portion (IA).
  • a certain degree of elasticity in length may be possible, for example, through the ductility of the inner portion (IA) itself formed with a relatively low average thickness, and deformation may be permitted to be customized to the shape and size of each individual pupil.
  • the pupil expansion portion (105) may include an inner portion (IA) having a relatively low average thickness and an outer portion (OA) having a relatively high average thickness, and may have an asymmetrical shape through the inner portions (IA) and the outer portions (OA) on both sides having different average thicknesses based on a maximum thickness portion (t5) formed at a central position between the inner annular edge (101) and the outer annular edge (102) of the pupil expansion portion (105).
  • the inner portion (IA) and the outer portion (OA) may have an asymmetrical shape based on the maximum thickness portion (t5), and the inner annular edge (101) and the outer annular edge (102) forming the ends of each of the inner portions (IA) and the outer portion (OA) may also have asymmetrical shapes with respect to each other.
  • the pupil expansion portion (105) includes a posterior slope (110) arranged toward the eyeball (EB) so as to be mounted on the eyeball (EB), and a front curved surface (120) formed with a thickness profile based on the posterior slope (110) arranged toward the outside (OS) opposite to the eyeball (EB), such that the inner annular edge (101) is formed while contacting the posterior slope (110) at a position in contact with the opening (OP), and the outer annular edge (102) is formed while contacting the posterior slope (110) at the opposite side of the opening (OP), and the front curved surface (120) formed with a thickness profile based on the posterior slope (110) so as to form a relatively thin inner portion (IA) and a relatively thick outer portion (OA) based on a maximum thickness portion (t5) that forms a maximum thickness between the inner annular edge (101) and the outer annular edge (102).
  • the front curved surface (120) forming a thickness profile on the rear inclined surface (110) can form a profile having a height and depth in the thickness direction along the inclination direction of the rear inclined surface (110) so as to form a variable thickness from the rear inclined surface (110).
  • the front curved surface (120) forming such a thickness profile can be formed along a spline curve in which the curvature or radius of curvature changes along the inclination direction of the rear inclined surface (110).
  • the inner annular edge (101) and the outer annular edge (102) may be formed in a rounded corner shape in which the front curved surface (120) and the rear inclined surface (110) forming the thickness of the pupil expansion portion (105) are in contact with each other. That is, in one embodiment of the present invention, both the inner annular edge (101) and the outer annular edge (102) may be formed in a rounded corner shape, and for example, may not be formed in an angular corner shape.
  • the curvature formed by the corner of the inner annular edge (101) and the curvature formed by the corner of the outer annular edge (102) may be set differentially from each other.
  • the curvature formed by the edge of the inner annular edge (101) may be formed smaller than the curvature formed by the edge of the outer annular edge (102), or in other words, the radius of curvature formed by the edge of the inner annular edge (101) may be formed larger than the radius of curvature formed by the edge of the outer annular edge (102).
  • an inner annular edge (101) that extends to a discontinuous edge (DE) between the cornea in the large curvature portion that protrudes convexly toward the front and the sclera in the small curvature portion extending posteriorly from the cornea among the membrane tissues that entirely surround the eyeball (EB) so as to maintain the shape of the eyeball (EB) can finish one side of the ocular implant (100) with a relatively gently rounded edge shape, and an outer annular edge (102) that adheres closely to the sclera in the large curvature portion can finish the other side of the ocular implant (100) with a relatively sharply rounded edge shape so as not to lift off from the sclera or to prevent a gap from being formed between the sclera and the cornea.
  • the inner portion (IA) needs to be in close contact with a geometrically singular point, such as a discontinuous edge (DE) formed by the sclera and the cornea, and, for example, the inner portion (IA) can be formed with a relatively low average thickness so as to be in close contact with the cornea as closely as possible, finely adjusted according to the size of the cornea.
  • a geometrically singular point such as a discontinuous edge (DE) formed by the sclera and the cornea
  • the inner portion (IA) may be formed with a relatively low average thickness in consideration of close contact with the discontinuous edge (DE) of the eyeball (EB), while being finished with a relatively gently rounded inner annular edge (101) in consideration of the possibility of damage to the internal tissue of the eyeball (EB).
  • the inner annular edge (101) which is inserted into the interior of the eyeball (EB) or into a relatively complex transplant space, such as a narrow transplant space or the discontinuous edge (DE) of the eyeball (EB), and forms contact with the internal tissue of the eyeball (EB), is formed in a relatively gently rounded shape, thereby preventing stimulation or damage to the internal tissue of the eyeball (EB) through the permanent procedure of the ocular implant (100).
  • the inner annular edge (101) can prevent stimulation or damage to the internal tissue of the eye (EB) through a relatively gently rounded shape, and in contrast, the outer annular edge (102) can block adverse effects such as the penetration of foreign substances or bacteria through a relatively sharply rounded shape.
  • the ocular implant (100) according to one embodiment of the present invention can be transplanted onto the sclera in a state that is relatively lifted from the surface of the sclera through the rounded edge of the outer annular edge (102), and for example, a gap can be provided between the ocular implant (100) and the sclera through the rounded edge of the outer annular edge (102).
  • the edge of the outer annular edge (102) relatively sharply, in other words, the front curved surface (120) forming the thickness of the outer portion (OA) forms a relatively high average thickness while forming a trajectory that is relatively far from the rear inclined surface (110), and then forms a sharply rounded edge at the outer annular edge (102) while following a relatively steep downward curve.
  • the front curve (120) forming the thickness of the outer portion (OA) follows a steep downward curve as it approaches the outer annular edge (102) to form a sharply rounded outer annular edge (102) with the rear slope (110), thereby closing the pupil expansion portion (105) through the sharply rounded outer annular edge (102) to form a gentle round, thereby blocking the penetration and adverse effects of foreign substances, bacteria, viruses, etc. that may be caused by lifting from the surface of the cornea.
  • the specific cross-section of the pupil expansion portion (105) including the front curved surface (120) and the rear inclined surface (110), and the inner annular edge (101) and the outer annular edge (102) where the front curved surface (120) and the rear inclined surface (110) contact each other can be designed in various numbers and shapes according to the specific design, but for example, in one embodiment of the present invention, the maximum thickness portion (t5) of the pupil expansion portion (105) can be set to a thickness of 50 ⁇ m to 200 ⁇ m (for example, 120 ⁇ m), the edge of the inner annular edge (101) can be set to a thickness of 20 ⁇ m to 100 ⁇ m (for example, 40 ⁇ m), and the edge of the outer annular edge (102) can be set to a thickness of 60 ⁇ m to 200 ⁇ m (for example, The thickness can be set to 80 ⁇ m.
  • the thickness (t1) formed by the edge of the inner annular edge (101) may refer to the thickness between the inner inflection point (101 ⁇ ) of the front curved surface (120), which forms a thickness profile on the rear inclined surface (110), and the rear inclined surface (110) while following a more downward curve through the inner inflection point (101 ⁇ ) to contact the rear inclined surface (110) to form the edge of the inner annular edge (101).
  • the thickness (t2) formed by the edge of the outer annular edge (102) may mean the thickness between the outer inflection point (102 ⁇ ) of the front curved surface (120), which forms a thickness profile on the rear inclined surface (110), and the rear inclined surface (110) while following a more downward curve through the outer inflection point (102 ⁇ ) to contact the rear inclined surface (110) to form the edge of the outer annular edge (102).
  • the pupil expansion portion (105) may include a profile of a front curved surface (120) approaching a rearward slope (110) from a maximum thickness portion (t5) on both sides, and the profile of the front curved surface (120) may form an inner annular edge (101) and an outer annular edge (102) while contacting the rearward slope (110) while following a more steeply downward profile through an inner inflection point (101 ⁇ ) and an outer inflection point (102 ⁇ ).
  • the distance from the outer annular edge (102) to the outer inflection point (102 ⁇ ) may be formed longer than the distance from the inner annular edge (101) to the inner inflection point (101 ⁇ ) along the slope direction.
  • the outer inflection point (102 ⁇ ) may be formed with a relatively deeper thickness moving downward to form a relatively sharply rounded outer annular edge (102) from a front curved surface (120) having a relatively high average thickness, and in other words, the inner inflection point (101 ⁇ ) may be formed with a relatively thinner thickness moving downward to form a relatively gently rounded inner annular edge (101) from a front curved surface (120) having a relatively low average thickness.
  • the distance from the outer inflection point (102 ⁇ ) to the outer annular edge (102) may be formed longer than the distance from the inner inflection point (101 ⁇ ) to the inner annular edge (101).
  • the outer inflection point (102 ⁇ ) and the inner inflection point (101 ⁇ ) may mean points that are bent downward relatively sharply to form an outer annular edge (102) and an inner annular edge (101) along the profile of the front curved surface (120), and for example, may mean two points that are bent downward at positions adjacent to the outer annular edge (102) and the inner annular edge (101), respectively, as two points having the greatest change in curvature through the profile of the front curved surface (120).
  • the thickness (t2) of the edge of the outer annular edge (102) may be formed to be higher than the thickness (t1) of the edge of the inner annular edge (101), and the thickness of the edge of the outer annular edge (102) corresponding to the distance moving downward from the outer inflection point (102 ⁇ ) may be formed to be relatively higher so as to form a sharply rounded outer annular edge (102) from the outer portion (OA) having a relatively high average thickness.
  • the thickness of the outer portion (OA) and the inner portion (IA), their average thickness, or the thickness (t2) of the edge of the outer annular edge (102), the thickness (t1) of the edge of the inner annular edge (101), etc. may correspond to the dimension of thickness that follows the vertical direction from the rear inclined surface (110), and while expressing the relationship of the size of the dimension of thickness, it is expressed as being high or low similarly to the dimension of height, but this is for the convenience of understanding, and may mean being thick or thin, respectively, in the dimension of thickness.
  • the posterior inclined surface (110) may be formed as a surface inclined at a constant tilting angle ( ⁇ ) from a vertical plane (G) perpendicular to the frontal direction (Z3) along the frontal direction (Z3) facing backward from the front where the pupil (or pupil) forming the receptor performing the function of the lens or the opening receiving light is formed, and the posterior inclined surface (110) may be formed to be inclined at a tilting angle ( ⁇ ) of approximately 20 degrees to 40 degrees on the vertical plane (G).
  • the posterior inclined surface (110) may be in close contact with the sclera, and for example, may be in close contact with the sclera having a relatively smaller curvature closer to the inclined surface than to the curved surface from the discontinuous edge (DE) between the cornea and the sclera to the curved portion (AC) of the sclera.
  • the section from the sclera beyond the discontinuous edge (DE) between the cornea and the sclera to the curvature (AC) of the sclera can be viewed as an approximately inclined plane rather than a curved surface, and the rear inclined plane (110) can be formed as an inclined plane inclined at a constant tilting angle ( ⁇ ) on the vertical plane (G) so as to adhere closely to the sclera having a small curvature close to the inclined plane.
  • the posterior slope (110) can be closely attached to a surface of the cornea that is formed approximately as an inclined surface or close to an inclined surface, and depending on the flexibility of the ocular implant (100) including the posterior slope (110) or the posterior slope (110), the posterior slope (110) can be closely attached to the cornea.
  • the posterior slope (110) can be formed as an inclined surface inclined at a constant tilting angle ( ⁇ ) from a vertical plane (G), thereby forming a support surface of the entire ocular implant (100).
  • the packaging container of the ocular implant (100) may include an inclined support surface formed to support a rear inclined surface (110), and considering the ease of manufacturing the ocular implant (100) and the packaging container of the ocular implant (100), the rear supporting surface of the ocular implant (100) and the supporting surface of the packaging container may be formed to follow the same constant inclined profile so as to provide a firm supporting force therebetween.
  • the inner annular edge (101) and the outer annular edge (102) form the front of the eyeball (EB), and can be observed as having an elliptical and circular shape, respectively, along a frontal direction (Z3) from the front of the eyeball (EB) toward the back of the eyeball (EB) where a crystalline lens performing a lens function and a pupil (or pupil) forming an entrance opening for light are arranged, and the rearward inclined surface (110) can be formed as a surface inclined at a constant tilting angle ( ⁇ ) from a vertical plane (G) perpendicular to the frontal direction (Z3) so that the inner annular edge (101) and the outer annular edge (102) form a front position and a rear position, respectively.
  • the ocular implant (100) may take a form in which, when observed from the frontal direction (Z3), the inner annular edge (101) at the front position and the outer annular edge (102) at the rear position overlap each other according to the slope of the rear inclined surface (110) that provides the thickness as a reference, and the oval of the inner annular edge (101) is included within the circular interior of the outer annular edge (102).
  • the pupil expansion portion (105) between the inner annular edge (101) and the outer annular edge (102) is formed so that one of the two positions along the short axis direction (Z2) of the inner annular edge (101) has a wider width than the other other position, and the oval of the inner annular edge (101) is biased toward the other position within the circular interior of the outer annular edge (102). can be formed at a location.
  • one side of the pupil expansion portion (105) formed with a relatively wide width among the two sides along the elliptical short axis direction (Z2) of the inner annular edge (101) may correspond to the central position (S) of the procedure, and at one side of the pupil expansion portion (105), a first end (E1, E2) separated from each other through an incision (C) and the incision (C), and a hole (10) for the procedure, a catch joint, a hook joint, etc. for connecting the first end (E1, E2) toward each other may be formed.
  • the inner annular edge (101) and the outer annular edge (102) can surround the opening (OP) along different shapes, for example, the inner annular edge (101) can be formed in an oval shape along the shape of the pupil so as to provide an appearance integrated with the pupil without covering the pupil (or pupil) forming the light entrance opening, and can surround the outer ring of the pupil at an adjacent position, and the outer annular edge (102) can be formed in a circular shape so as to provide an appearance of an attractive circle.
  • the inner annular edge (101) may be formed into an oval shape having different major axis lengths (L1) and minor axis lengths (L2), wherein the major axis length (L1) may be formed along a direction in which a pair of eyes of the transplanter face each other, and the minor axis length (L2) may be formed along a direction perpendicular to the major axis length (L1).
  • the inner annular edge (101) surrounding the outer ring of the pupil of the recipient may be formed into an elliptical shape according to the shape of the pupil of the recipient, and may be deformed into an elliptical shape optimized for the shape and size of the pupil that are differentially formed for each recipient, for example, the individual physical condition of the recipient.
  • the major axis length (L1) of the pupil may be formed to be 9 mm to 15 mm (ex. 12 mm)
  • the minor axis length (L2) may be formed to be 8 mm to 14 mm (ex.
  • the shape of the pupil may be formed into a slip-shaped ellipse in which the major axis length (L1) is relatively longer than the average shape, or a root-shaped ellipse in which the minor axis length (L2) is relatively longer than the average shape, depending on the shape ratio between the major axis length (L1) and the minor axis length (L2).
  • an ocular implant (100) which comprises an adaptive elastic portion (151) that adaptively provides length expansion along the perimeter of an inner annular edge (101), and a roughened surface (152, 153) for generating rotational resistance in the direction of rotation along the perimeter of a pupil expansion portion (105) formed between the inner annular edge (101) and the outer annular edge (102).
  • FIG. 6 is a perspective view illustrating an adaptive elastic member (151) applied to an ocular implant (100) according to one embodiment of the present invention.
  • FIG. 7 is a perspective view for explaining an adaptive elastic member (151) applied to an ocular implant (100) according to one embodiment of the present invention, and is a perspective view for explaining a modified example of FIG. 6.
  • FIGS. 8A and 8B are cross-sectional views of an ocular implant (100) taken along the circumferential direction of a pupil dilatation portion (105), illustrating different roughness-processed surfaces (152, 153) having isotropic rotational resistance and anisotropic rotational resistance, respectively.
  • It may include an adaptive elastic member (151) that adaptively provides length expansion along the perimeter of the inner annular edge (101).
  • the adaptive elastic member (151) may provide longitudinal elasticity along the perimeter of the inner annular edge (101) so as to adaptively change to the shape and size of the pupil of each recipient.
  • the inner annular edge (101) is formed in an oval shape having different major axis lengths (L1) and minor axis lengths (L2).
  • the adaptive elastic member (151) can provide length expansion along the major axis direction (Z1) and/or the minor axis direction (Z2) to adaptively provide an inner annular edge (101) of a slip-shaped ellipse with a relatively long axis length (L1) elongated and/or a short axis length (L2) shortened, and a root-shaped ellipse with a relatively long axis length (L1) shortened and/or a short axis length (L2) elongated, suitable for the pupil of the recipient.
  • the adaptive elastic member (151) may include at least one slit (151s) formed around the perimeter of the inner annular edge (101).
  • the adaptive elastic member (151) may include a plurality of slits (151s) formed spaced apart from each other along the perimeter of the inner annular edge (101).
  • the plurality of slits (151s) may be formed spaced apart from each other at equal intervals along the perimeter of the inner annular edge (101).
  • the adaptive elastic member (151) may include a group of slits (151s) formed at both ends along the longitudinal direction (Z1) and/or at both ends along the short-axis direction (Z2).
  • the adaptive elastic member (151) is the adaptive elastic member.
  • the pieces divided through the third and fourth groups of slits (151s) formed at both sides along the longitudinal direction (Z1) can overlap each other to extend the longitudinal length (L1) and shorten the short-axis length (L2).
  • the slit (151s) can be formed at positions spaced apart by a constant angle with the center (O) of the opening (OP) where the major axis length (L1) and the minor axis length (L2) of the inner annular edge (101) intersect each other as the rotation center.
  • It may include third and fourth groups of slits (151s) formed at 90 degree angle positions (A3) and 270 degree angle positions (A4) corresponding to opposite sides along the longitudinal direction (Z1), respectively.
  • the slit (151s) may be introduced into the interior of the pupil expansion portion (105) along a depth direction from the inner annular edge (101) toward the outer annular edge (102).
  • the slit (151s) can be introduced into the interior of the pupil expansion portion (105) in a radial direction in the depth direction from the center (O) of the opening (OP) where the major axis length (L1) and the minor axis length (L2) intersect.
  • the adaptive elastic member (151) can stretch the length of the inner annular edge (101) by overlapping pieces divided from each other through the slits (151s) along the perimeter of the inner annular edge (101).
  • the pupil expansion part (105) is the pupil expansion part (105)
  • the front curved surface (120) is arranged toward the outer world (OS) opposite to the above-mentioned eye (EB), and forms a thickness profile based on the rear slope (110), forming an inner annular edge (101) while contacting the rear slope (110) at a position in contact with the above-mentioned opening (OP), forming an outer annular edge (102) while contacting the rear slope (110) on the opposite side of the above-mentioned opening (OP), and forming a relatively thin inner portion (IA) and a relatively thick outer portion (OA) based on the maximum thickness portion (t5) forming the maximum thickness between the inner annular edge (101) and the outer annular edge (102), and forming a thickness profile based on the rear slope (110).
  • OS outer world
  • EB above-mentioned eye
  • the pieces divided through the slits (151s) forming the above-described adaptive elastic portion (151) can form an extra thickness by overlapping each other while stretching the length of the inner annular edge (101) and increasing the thickness of the inner portion (IA) where the slits (151s) introduced from the inner annular edge (101) are formed.
  • the adaptive elastic portion (151) is formed on the inner annular edge (101) surrounding the outer ring of the pupil at a position relatively closer to the outer annular edge (102) so as to adaptively change to the shape and size of the pupil of each transplant recipient.
  • the outer annular edge (102) may not be formed.
  • the inner annular edge (101) in which the pieces divided through the slit (151s) forming the adaptive elastic portion (151) are arranged to overlap each other is formed in a relatively gently rounded corner shape
  • the above outer annular edge (102) can be formed into a relatively sharply rounded corner shape.
  • the shape and size of the pupil corresponding to the enlargement target can be differentially formed according to the physical condition of the recipient, and the inner annular edge (101) can form an enlarged pupil that is integrated with the pupil without blocking the pupil (or pupil) forming the light entrance aperture, so that the ocular implant (100) can absorb the shape and size of the pupil according to the individual physical condition of the recipient, and can include an adaptive elastic portion (151) that can adaptively expand in length along the circumferential direction of the inner annular edge (101).
  • the adaptive elastic portion (151) can provide expansion in length along the circumference of the inner annular edge (101) so as to be adaptively deformed to the shape and size of the pupil of each recipient.
  • the adaptive elastic member (151) adaptively providing length expansion along the circumferential direction of the inner annular edge (101) may include providing length expansion along one of the elliptical major axis direction (Z1) and minor axis direction (Z2) of the inner annular edge (101), or providing length expansion along the other other direction, and may include expanding or shortening the circumference of the inner annular edge (101) as a whole without being restricted to a specific direction.
  • the adaptive elastic portion (151) may include a plurality of slits (151s) formed in the inner annular edge (101) or the pupil dilatation portion (105) adjacent to the inner annular edge (101).
  • the adaptive elastic portion (151) may include at least one slit (151s) formed around the inner annular edge (101), and in one embodiment of the present invention, the adaptive elastic portion (151) may include a plurality of slits (151s) spaced apart from each other along the circumferential direction of the inner annular edge (101) and introduced from the inner annular edge (101) toward the pupil dilatation portion (105).
  • an ocular implant (100) that can be performed universally but is designed to be adaptively stretchable to the shape and size of each individual pupil is manufactured, and then, during the surgery, the implant is adapted to the shape and size of each recipient's pupil, thereby performing an ocular implant (100) optimized for the shape and size of the pupil that is differentially formed.
  • each individually individualized ocular implant (100) rather than introducing individually formed molds to manufacture each individually individualized ocular implant (100), forming a plurality of ocular implants (100) through a mold with a universal single design can reduce the manufacturing cost, thereby promoting an economical product design.
  • the adaptive elastic portion (151) may include a plurality of slits (151s) formed to be spaced apart from each other along the periphery of the inner annular edge (101), and the slits (151s) may be introduced from the inner annular edge (101) toward the pupil expansion portion (105) from each position along the periphery of the inner annular edge (101).
  • the inner annular edge (101) may correspond to an innermost configuration surrounding the outer ring of the pupil in the ocular implant (100), for example, a configuration directly surrounding the outer ring of the pupil, or a configuration in which an elastic deformation is induced for a design optimized for the shape and size of the pupil of each implant operator.
  • the inner annular edge (101) can be deformed with a high degree of freedom according to the optimized shape or size of the pupil of each implant operator, for example, shape deformation such as distortion and deformation such as overall length elongation, through the adaptive expansion portion (151), so as to be optimized for the shape and size of the pupil of each implant operator, that is, so as to surround pupils of various shapes and sizes at the closest positions without covering the pupil (or pupil) corresponding to the light entrance aperture.
  • the length elongation of the inner annular edge (101) can comprehensively mean both shape deformation such as distortion of the inner annular edge (101) as described above and elongation of the overall length of the inner annular edge (101).
  • the adaptive elastic member (151) may include a plurality of slits (151s) spaced apart from each other along the perimeter of the inner annular edge (101), for example, the plurality of slits (151s) may be formed at equal intervals along the perimeter of the inner annular edge (101), for example, may be formed at equal angular positions spaced apart at a constant angle with respect to the center (O) of the opening (OP) as the rotation center.
  • the slits (151s) forming the adaptive elastic portion (151) can be introduced into the interior of the pupil expansion portion (105) along a depth direction from the inner annular edge (101) toward the outer annular edge (102). More specifically, each slit (151s) forming the adaptive elastic portion (151) can be formed in a form introduced from the inner annular edge (101) toward the interior of the pupil expansion portion (105), for example, each slit (151s) can be introduced toward the interior of the pupil expansion portion (105) along a direction perpendicular to the inner annular edge (101) from each location of the inner annular edge (101).
  • the slit (151s) may be introduced from the inner annular edge (101) in a direction perpendicular to the inner annular edge (101) or may be introduced radially from the inner annular edge (101).
  • the slit (151s) may be introduced radially in a depth direction toward the center (O) of the opening (OP) surrounded by the inner annular edge (101) into the interior of the pupil dilatation portion (105) adjacent to the inner annular edge (101).
  • the center (O) of the opening (OP) surrounded by the inner annular edge (101) may mean the center (O) of the opening (OP) where the major axis length (L1) and the minor axis length (L2) of the elliptical inner annular edge (101) or the elliptical opening (OP) intersect each other.
  • the slit (151s) may be introduced into the interior of the pupil expansion portion (105) along various directions from the inner annular edge (101), and the depth direction in which the slit (151s) is introduced may be variously set according to a shape formed by the inner annular edge (101), for example, an elliptical shape formed by the inner annular edge (101), and, as described below, according to a deformation of the inner annular edge (101) induced according to an individual physical condition of an implant recipient.
  • the slits (151s) forming the adaptive elastic portion (151) may be formed in a range of 30 to 360 along the periphery of the inner annular edge (101), and for example, when they are evenly spaced apart at a constant angle, they may be formed in a range of about 30 at an angle of about 12 degrees, or in a range of about 360 at an angle of about 1 degree.
  • the width (d) of the slits (151s) forming the adaptive elastic portion (151) may be formed to be about 1/4 to 1/2 of the width of the pupil expansion portion (105) between the inner annular edge (101) and the outer annular edge (102) along the depth direction from the inner annular edge (101) toward the outer annular edge (102).
  • the inner annular edge (101) may be formed into an oval shape having different major axis lengths (L1) and minor axis lengths (L2), and the adaptive elastic portion (151) may provide a length extension along the major axis direction (Z1) and/or the minor axis direction (Z2) to adaptively provide an inner annular edge (101) of a slip-type oval shape in which the major axis length (L1) is relatively elongated and/or the minor axis length (L2) is relatively shortened, and a root-type oval shape in which the major axis length (L1) is relatively shortened and/or the minor axis length (L2) is elongated, suitable for the pupil of the recipient.
  • the inner annular edge (101) or the pupillary expansion portion (105) adjacent to the inner annular edge (101) may be divided into a plurality of pieces along the circumferential direction of the inner annular edge (101) through each of the slits (151s), and the length of the inner annular edge (101) may be expanded as the plurality of pieces divided into both sides of each of the slits (151s) along the circumferential direction of the inner annular edge (101) overlap each other.
  • the adaptive expansion portion (151) including an array of a plurality of slits (151s) may be deformed so that the shape and length of the entire inner annular edge (101) may be expanded as the pieces divided through each of the slits (151s) overlap each other so as to be close to each other through the slits (151s).
  • the inner annular edge (101) to which the adaptive elastic portion (151) is applied or the inner portion (IA) having the inner annular edge (101) as an end portion can be relatively freely deformed while being formed with a relatively low average thickness.
  • the inner portion (IA) with a relatively low average thickness can provide a free space along the thickness direction so as to accommodate overlapping of pieces divided through the slit (151s).
  • the adaptive elastic portion (151) formed on the inner annular edge (101) and the inner portion (IA) formed with a relatively low average thickness and having the inner annular edge (101) as an end can cooperate with each other to adaptively deform the inner annular edge (101) into a shape and size optimized according to the physical condition of the implant surgeon, and for example, the inner annular edge (101) formed with a relatively low average thickness can provide ductility that is advantageous for deforming so that the pieces divided through the slit (151s) approach each other and overlap each other, and further, the inner portion (IA) formed with a relatively low average thickness can provide a space that can accommodate extra thickness formed when the pieces divided through the slit (151s) overlap each other.
  • the pupil expansion portion (105) has a posterior slope (110) arranged toward the eyeball (EB) so as to be in close contact with the eyeball (EB), and is arranged toward the outside (OS) opposite the eyeball (EB) and forms a thickness profile based on the posterior slope (110), so as to form an inner annular edge (101) while contacting the posterior slope (110) at a position in contact with the opening (OP), and an outer annular edge (102) while contacting the posterior slope (110) at the opposite side of the opening (OP), and forms a maximum thickness portion (t5) between the inner annular edge (101) and the outer annular edge (102), and forms a thickness profile based on the posterior slope (110) to form a relatively thin inner portion (IA) and a relatively thick outer portion (OA).
  • a posterior slope (110) arranged toward the eyeball (EB) so as to be in close contact with the eyeball (EB), and is arranged toward the outside (OS) opposite the eyeball (EB) and forms a thickness profile based on the posterior slope (110), so as to
  • the pieces which may include a curved surface (120), are divided into pieces through the slits (151s) forming the adaptive elastic portion (151) and overlap each other to increase the thickness of the inner portion (IA) where the slits (151s) introduced from the inner annular edge (101) are formed while stretching the length of the inner annular edge (101), thereby forming extra thickness.
  • the pupil surrounded by the inner annular edge (101) may be formed in an oval shape having different major axis lengths (L1) and minor axis lengths (L2) when observed in a frontal direction (Z3), and the major axis length (L1) of the oval formed by the pupil may be formed along a direction in which a pair of eyes face each other, and the minor axis length (L2) of the oval formed by the pupil may be formed along a direction perpendicular to the major axis length (L1).
  • the major axis length (L1) formed by the pupil may be formed to be 9 mm to 15 mm
  • the minor axis length (L2) formed by the pupil may be formed to be 8 mm to 14 mm.
  • the shape and size of the pupil to be enlarged by the ocular implant (100) may have the deviation as described above, and for example, even if the pupil has different shapes of the minor axis length (L2) and the major axis length (L1), it may be formed into different elliptical shapes and different sizes due to the dispersion of the lengths as described above.
  • the shape and size of the inner annular edge (101) may need to be transformed into a slip-shaped ellipse having a relatively longer major axis length (L1) and/or a relatively shorter minor axis length (L2) compared to the average shape and size, or may need to be transformed into a proto-ellipse having a relatively longer minor axis length (L2) and/or a relatively shorter major axis length (L1) and approaching a circle, depending on the physical condition of each individual implant recipient.
  • ovals such as a slip-shaped oval or a root-shaped oval
  • L1 and L2 the relative shape ratio between the major axis length (L1) and the minor axis length (L2), and may not mean individual lengths or absolute lengths of the major axis length (L1) and the minor axis length (L2).
  • the fact that the major axis length (L1) is relatively elongated or the minor axis length (L2) is relatively elongated to optimize the shape and size of the differential pupil of the recipient may mean that the deformation of the adaptive elastic member (151) is induced so that the relative shape ratio of the major axis length (L1) and the minor axis length (L2) defining the oval shape of the inner annular edge (101) surrounding the outer ring of the pupil of the recipient is changed.
  • the inner annular edge (101) surrounding the pupil can be designed to fit the shape and size of an average pupil that does not require deformation of a separate adaptive elastic portion (151) or the inner portion (IA), and a single-design ocular implant (100) that can be universally operated can be manufactured to fit the pupil of the average shape and size without deformation.
  • the shape of the opening (OP) surrounded by the inner annular edge (101) can be formed as an oval having a relatively long major axis length (L1) and a relatively short minor axis length (L2), and for example, the major axis length (L1) and the minor axis length (L2) of the oval formed by the opening (OP) at the center can be formed to be 12 mm and 11 mm to fit the average pupil.
  • a plurality of slits (151s) may be formed along the perimeter of the inner annular edge (101), and the plurality of slits (151s) may be formed evenly along the entire perimeter of the inner annular edge (101).
  • the plurality of slits (151s) formed evenly along the perimeter of the inner annular edge (101) may induce different deformations according to the individual physical conditions of each implant recipient.
  • the divided pieces in order to optimize the slip-shaped oval pupil which needs to further extend the major axis length (L1) according to the shape of the pupil of the implant recipient having each different physical condition from the inner annular edge (101) of the oval shape in which no deformation is induced, can be overlapped with each other through slits (151s) formed at both sides along the major axis length (L1) of the inner annular edge (101) to extend the major axis length (L1) instead of shortening the minor axis length (L2).
  • the divided pieces can be overlapped with each other through slits (151s) formed at both sides along the minor axis length (L2) of the inner annular edge (101) to extend the minor axis length (L2) instead of shortening the major axis length (L1).
  • the inner annular edge (101) which is deformed into an optimized shape at each location where each slot is formed through slots which are evenly formed along the circumference of the inner annular edge (101)
  • deformation can be flexibly absorbed according to deformation induced in the inner annular edge (101), and depending on the degree and direction of deformation induced in the inner annular edge (101), damage to the ocular implant (100) including the inner annular edge (101) due to distortion caused by failure to maintain coplanarity due to an excess inner annular edge (101) or excessive stress and stress accumulation due to an insufficient inner annular edge (101) can be prevented.
  • the adaptive elastic portion (151) may include a plurality of slits (151s) formed concentratedly at both sides along the major axis length (L1) and a plurality of slits (151s) formed concentratedly at both sides along the minor axis length (L2), and, for example, when observed in the frontal direction (Z3), along the perimeter of the inner annular edge (101), at a 0 degree angle position (A1), a 90 degree
  • the adaptive elastic portion (151) may include a first group of slits (151s) formed at 0-degree angle positions (A1) corresponding to opposite positions along the short-axis direction (Z2) along the perimeter of the inner annular edge (101) and a second group of slits (151s) formed at 180-degree angle positions (A2), and the first and second groups of slits (151s) formed at 0-degree angle positions (A1) and 180-degree angle positions (A2), respectively, may be formed at opposite positions along the short-axis direction (Z2) to provide elongation of the short-axis length (L2) or shortening of the long-axis length (L1), and further, the adaptive elastic portion (151) may include a third group of slits (151s) formed at 90-degree angle positions (A3) corresponding to opposite positions along the long-axis direction (Z1) along the perimeter of the inner annular edge (101).
  • It may include a slit (151s) of the third group formed at a 90 degree angle position (A3) and a 270 degree angle position (A4) and a slit (151s) of the fourth group formed at the 90 degree angle position (A3) and the 270 degree angle position (A4), and the slits (151s) of the third and fourth groups formed at the 90 degree angle position (A3) and the 270 degree angle position (A4) are formed at opposite positions along the major axis direction (Z1), thereby providing an extension of the major axis length (L1) or a shortening of the minor axis length (L2).
  • a plurality of slits (151s) forming the adaptive elastic portion (151) may be formed at equal intervals with a constant angle between them along the perimeter of the inner annular edge (101), but the first to fourth groups of slits (151s) arranged with a 90-degree angle between them, which contributes relatively greatly to the elasticity of the major axis length (L1) and the elasticity of the minor axis length (L2), or arranged at opposite positions in the major axis direction (Z1) and the minor axis direction (Z2), may be formed intensively around the 0-degree angle position (A1), the 90-degree angle position (A3), the 180-degree angle position (A2), and the 270-degree angle position (A4), for example, the first to fourth groups of slits (151s) may be formed at an outer angle from the inner annular edge (101) than the other slits (151s). It can be formed at a deeper depth along the depth direction toward the annular edge (102) or
  • the adaptive elastic member (151) may include a first group of slits (151s) concentratedly arranged around a 0 degree angle position (A1), a second group of slits (151s) concentratedly formed around a 180 degree angle position (A2), a third group of slits (151s) concentratedly arranged around a 90 degree angle position (A3), and a fourth group of slits (151s) concentratedly arranged around a 270 degree angle position (A4), and each of the first to fourth groups of slits (151s) may be formed in a different number, for example, may include at least one slit (151s).
  • the first to fourth groups of slits (151s) may each include one slit (151s), and may include a single slit (151s) formed at a 0 degree angular position (A1), a 90 degree angular position (A3), a 180 degree angular position (A2), and a 270 degree angular position (A4), respectively.
  • slits (151s) introduced at a relatively deep depth or slits (151s) arranged with a relatively tight angle may be formed, and at the remaining angular positions, slits (151s) introduced at a relatively thin depth or slits (151s) arranged with a relatively tight angle may be formed.
  • the adaptive elastic portion (151) may not be formed on the outer annular edge (102).
  • the adaptive elastic portion (151) formed on the inner annular edge (101) is formed in consideration of the shape and size of the pupil, which are formed differentially for each individual, and is configured to induce deformation so that a single-design ocular implant (100) that can be universally operated or a single-design mold can be used to drastically reduce the manufacturing cost while enabling permanent implantation in a form optimized for the individual physical condition of each implant recipient.
  • the outer annular edge (102) may not be formed with a structure that induces deformation or is advantageous to deformation.
  • the deformation induced in the inner annular edge (101) is followed while unintended deformation of the outer annular edge (102) occurs. Accordingly, the originally designed circular appearance can be prevented from being damaged, thereby preventing the beautiful appearance imparted to the outer annular edge (102) from being damaged, and the beautiful circular appearance as originally designed can be maintained.
  • the outer annular edge (102) is formed in a circular shape, thereby increasing the satisfaction with the appearance, and a structure (adaptive elastic portion 151) that is advantageous to deformation, such as a slit (151s), may not be formed on the outer annular edge (102) so as to maintain the circular appearance of the outer annular edge (102) despite deformation induced in the inner annular edge (101), for example, excessive deformation induced in the inner annular edge (101) to match a slip-type elliptical pupil or a root-type elliptical pupil.
  • the outer annular edge (102) can be formed with relatively higher rigidity than the inner annular edge (101), and can be formed with a relatively higher average thickness than the inner annular edge (101) so as to form a difference in rigidity through different shape designs while being formed with the same material, and thus, in one embodiment of the present invention, the outer annular edge (102) can have higher shape stability or shape maintaining power than the inner annular edge (101), and can maintain a beautiful circular shape despite deformation induced in the inner annular edge (101).
  • the pupil expansion portion (105) forming the ocular implant (100) or the body of the ocular implant (100) may include a posterior slope (110) facing the eyeball (EB) and a front curved surface (120) facing the outer world (OS) opposite the eyeball (EB).
  • the outer world (OS) opposite the eyeball (EB) may mean the outer world of the eyeball (EB) itself rather than the outer world of the body, and for example, a body tissue such as an eyelid covering the front of the eyeball (EB) may also correspond to the outer world (OS) of the eyeball (EB).
  • the above ocular implant (100) can be transplanted onto the sclera so that the posterior slope (110) adheres closely to the sclera, and can be formed with a roughened surface (152, 153) having an appropriate roughness so as to generate appropriate friction with the sclera.
  • the posterior slope (110) and the anterior curved surface (120) can be formed with different roughnesses or different roughnesses, and the posterior slope (110) can be formed with a roughened surface (152, 153) so as to have an appropriate roughness or roughness that can induce friction, and the anterior curved surface (120) can be formed with a smooth surface so as to form an attractive appearance.
  • the ocular implant (100) may be formed in a rotationally asymmetric shape rather than being formed in a rotationally symmetric shape.
  • the inner annular edge (101) surrounding the pupil of the ocular implant (100) may be formed in an oval shape having different major axis lengths (L1) and minor axis lengths (L2).
  • the ocular implant (100) formed in a rotationally asymmetric shape in this way may be arbitrarily rotated on the eyeball (EB) formed in a spherical shape.
  • the posterior slope (110) facing the eyeball (EB) may be formed as a roughened surface (152, 153) formed with an appropriate roughness to induce friction.
  • the rear inclined surface (110) may be formed in any shape capable of inducing friction, and may be formed in any concave-convex shape capable of forming a roughness.
  • the rear inclined surface (110) may include a roughening surface (152, 153) in which continuous concave-convex shapes are repeatedly formed, such as a wave shape, and in various embodiments of the present invention, the roughening surface (152) may be formed to have an isotropic rotational resistance to induce the same friction along one rotational direction and an opposite rotational direction, or the roughening surface (153) may be formed to have an anisotropic rotational resistance to induce different friction along one rotational direction and an opposite rotational direction.
  • the roughened surface (153) providing the anisotropic rotational resistance may be formed as a waveform having anisotropy along the rotational direction, and for example, it may be formed as a waveform having a relatively lying shape along one rotational direction corresponding to the transplantation direction, and a relatively low rotational resistance is formed through a waveform having a gentle slope along one rotational direction corresponding to the transplantation direction, and a relatively low rotational resistance is formed through a waveform having a gentle slope along one rotational direction opposite to the transplantation direction.
  • a relatively high rotational resistance can be formed through a steeply inclined waveform along the rotational direction.
  • the roughened surface (152, 153) formed on the rear inclined surface (110) can be formed along the periphery of the pupil expansion portion (105), and, for example, can be implanted along one rotational direction to surround the outer ring of the pupil, thereby forming a relatively small rotational resistance along one rotational direction and forming a relatively large rotational resistance along an opposite rotational direction different from one rotational direction, thereby providing a position fixing force for the surgical position of the ocular implant (100).
  • the inner annular edge (101) is configured to surround the pupil of the recipient at the closest position, and is located at a position that does not overlap with the pupil so as not to interfere with the incidence of light toward the pupil, that is, while surrounding the outer ring of the pupil, considering that if it is excessively spaced from the pupil, which forms a dark area with a relatively low brightness, it may not provide an appearance that is integrated with the pupil and the satisfaction with the appearance of the enlarged pupil may decrease, it may be preferable to form it to reflect the shape of the pupil at a position as close to the pupil as possible.
  • the inner annular edge (101) may be formed in an elliptical shape reflecting the shape of the pupil, and may surround the outer ring of the pupil in an elliptical shape optimized for the pupil of the recipient that is differentially formed through the adaptive elastic portion (151) formed on the inner annular edge (101).
  • the outer annular edge (102) can be formed in a circular shape so that the outer shape of the expanded pupil can be observed as a circle, and unlike the inner annular edge (101), instead of the problem of obstructing the incidence of light toward the pupil, it can be formed in a circular shape so that the outer shape of the expanded pupil can be substantially determined and a more beautiful appearance can be provided.
  • a plurality of slits (151s) forming the adaptive elastic portion (151) may be formed along the periphery of the inner annular edge (101), and the pieces divided through the plurality of slits (151s) formed along the periphery of the inner annular edge (101) may overlap each other to provide an elongation along the periphery of the inner annular edge (101).
  • the inner annular edge (101) where the slits (151s) are formed may be formed in a relatively gently rounded corner shape, for example, may be formed in a relatively gently rounded corner shape rather than the outer annular edge (102) which is formed in a relatively sharply rounded corner shape.
  • a piece of the inner annular edge (101) or the inner annular edge (101) divided through a slit (151s) with a relatively gently rounded edge shape can provide a gap lifted from the bottom through the gently rounded edge shape, and can easily enter the lower part of another adjacent piece through the gap lifted from the bottom and overlap with another piece, and the length of the inner annular edge (101) can be easily expanded.
  • an ocular implant (100) according to another aspect of the present invention, a surgical hole (10), a catch joint, or a hook joint that connects the first and second ends (E1, E2) separated from each other through an incision (C) toward each other will be described.
  • FIG. 9 is a drawing for explaining a surgical hole (10) applied to an ocular implant according to one embodiment of the present invention, and is a plan view of an ocular implant (100) viewed from the front.
  • FIGS. 10A to 10C are perspective views of different ocular implants (100) illustrating the engagement of the first and second slits (154a, 154b, 155a, 155b) with the catch or the hook according to different embodiments of the present invention.
  • FIGS. 11a and 11b illustrate different drawings for explaining the catch joint or hook joint of the assembly slit (156a) and the assembly hole (156b) applied to the ocular implant (100) according to one embodiment of the present invention.
  • It may include a pupil expansion portion (105) formed between the inner annular edge (101) and the outer annular edge (102), including first and second ends (E1, E2) separated from each other through an incision (C) and connected toward each other through a surgical hole (10) formed therein.
  • the pupil expansion portion (105) between the inner annular edge (101) and the outer annular edge (102) is formed so that one of the two positions along the short axis direction (Z2) of the inner annular edge (101) is formed with a wider width than the other position, and the oval of the inner annular edge (101) is formed at a biased position that is biased toward the other position within the circular shape of the outer annular edge (102).
  • the above-mentioned incision (C), the first and second ends (E1, E2) separated from each other through the above-mentioned incision (C), and the surgical hole (10) formed on the first and second ends (E1, E2) can be formed at the one-sided position formed with a relatively wide width along the short-axis direction (Z2).
  • the positions on both sides along the short axis direction (Z2) of the inner annular edge (101) are formed with a relatively smaller curvature than the positions on both sides along the long axis direction (Z1) of the inner annular edge (101).
  • the above-mentioned treatment hole (10) can be formed at either one of the two sides along the short-axis direction (Z2) formed with a relatively small curvature.
  • the above-mentioned incision (C) is formed along the short-axis direction (Z2) of the inner annular edge (101),
  • the first and second ends (E1, E2) separated from each other through the above-mentioned cutting portion (C) are connected to each other along the longitudinal direction (Z1) of the inner annular edge (101).
  • a plurality of surgical holes (10) arranged along the longitudinal direction (Z1) of the inner annular edge (101) may be formed in each of the first and second ends (E1, E2).
  • the above treatment hole (10) is
  • the first treatment hole (11) is formed with a relatively small diameter
  • the above second treatment hole (12) can be formed with a relatively large diameter.
  • the first treatment hole (11) is formed at a location relatively close to the incision (C),
  • the above second surgical hole (12) can be formed at a location relatively far from the incision (C).
  • an ocular implant (100) according to another aspect of the above-mentioned aspect is
  • It may include a pupil expansion portion (105) formed between the inner annular edge (101) and the outer annular edge (102), and including first and second ends (E1, E2) separated from each other through a cut portion (C) and forming a catch joint or hook joint with respect to each other.
  • a pupil expansion portion (105) formed between the inner annular edge (101) and the outer annular edge (102), and including first and second ends (E1, E2) separated from each other through a cut portion (C) and forming a catch joint or hook joint with respect to each other.
  • the pupil expansion portion (105) between the inner annular edge (101) and the outer annular edge (102) is formed so that one of the two positions along the short axis direction (Z2) of the inner annular edge (101) is formed with a wider width than the other position, and the oval of the inner annular edge (101) is formed at a biased position that is biased toward the other position within the circular shape of the outer annular edge (102).
  • the above-mentioned cut portion (C), the first and second ends (E1, E2) separated from each other through the above-mentioned cut portion (C), and the catch joint or hook joint between the first and second ends (E1, E2) can be formed at the one-piece position formed with a relatively wide width along the short-axis direction (Z2).
  • first and second slits (154a, 154b, 155a, 155b) respectively formed on the first and second ends (E1, E2).
  • the first and second slits (154a, 154b, 155a, 155b)
  • It may include a second portion (1542, 1552) extending from the first portion (1541, 1551) toward the inner annular edge (101) or the outer annular edge (102) along a diagonal direction that simultaneously follows the short axis direction (Z2) of the inner annular edge (101) or the short axis direction (Z2) and the long axis direction (Z1) and opens to the outside of the ocular implant (100).
  • first and second slits may be formed in complementary shapes to form a catch joint or a hook joint with respect to each other and may be fitted into each other.
  • the first part (1541, 1551) of the first and second slits (154a, 154b, 155a, 155b) extends parallel to the longitudinal direction (Z1) of the inner annular edge (101),
  • the second portions (1542, 1552) of the first and second slits (154a, 154b, 155a, 155b) may be formed in complementary shapes, such that one of the first and second slits (154a, 154b, 155a, 155b) and the second portions (1542, 1552) of the other one may extend in opposite directions toward the outer annular edge (102) and the inner annular edge (101), respectively, and may be opened toward the outside of the ocular implant (100).
  • the above-mentioned incision (C) is formed along the short-axis direction (Z2) of the inner annular edge (101),
  • first and second ends (E1, E2) are adjacent to each other along the longitudinal direction (Z1) of the inner annular edge (101),
  • first and second slits (154a, 154b, 155a, 155b)
  • one of them may include an array of first slits (154a, 155a) or an array of second slits (154b, 155b) formed in a plurality on the first end (E1) or the second end (E2) along the longitudinal direction (Z1), and the other may be formed as a single second slit (154b, 155b) or a single first slit (154a, 155a).
  • It may include an assembly hole (156b) formed in the second end (E2) above and into which an assembly slit (156a) is fitted.
  • an assembly guide portion (158) may be formed at a forward position of the assembly slit (156a) along the assembly direction between the first and second ends (E1, E2).
  • It includes a projection (158a) of the front end formed with a relatively narrow width at the front end of the first end (E1) along the assembly direction of the first and second ends (E1, E2), and a rear end (158c) formed at the rear of the projection (158a) of the front end and in front of the assembly slit (156a) and with a relatively wider width than the bottleneck (W1) of the assembly slit (156a).
  • a variable width portion (158b) may further be included in a shape that converges toward the projection (158a) of the front end along a diagonal direction that simultaneously follows the major axis direction (Z1) corresponding to the assembly direction and the minor axis direction (Z2) intersecting the major axis direction (Z1) to connect the differential widths between the projection (158a) of the front end formed with a relatively narrow width and the rear end (158c) formed with a relatively wide width.
  • the rear end (158c) of the assembly induction part (158) can be connected to the full width (W0) of the first end (E1) interposed between the assembly induction part (158) and the assembly slit (156a).
  • a cutting line (CL) including an array of perforations formed in multiple numbers may be formed between the assembly induction member (158) and the full width (W0) of the first end (E1).
  • the assembly slit (156a) is introduced on both sides from the inner annular edge (101) and the outer annular edge (102) along the shortening direction (Z2) of the inner annular edge (101) to form a bottleneck (W1) of minimum width.
  • An ocular implant (100) may be inserted between the sclera and the conjunctiva by forming an incision (EBC) in the conjunctiva surrounding the sclera and inserting the implant between the sclera and the conjunctiva through the incision (EBC) of the conjunctiva so as to surround the outer ring of the pupil along the sclera and the conjunctiva corresponding to the outer ring of the pupil.
  • the ocular implant (100) can be inserted along the rotational direction so as to circle the outer ring of the pupil.
  • the ocular implant (100) may be formed in a form that is disconnected from each other through a cut portion (C) formed along a certain angular position (0 degree angular position A1) with the center (O) of the opening (OP) as the rotational center, rather than being formed continuously along the rotational direction that circles the outer ring of the pupil, and first and second ends (E1, E2) that are disconnected from each other through the cut portion (C) may be formed.
  • the ocular implant (100) may include an opening (OP) that is open to the outside through the cut portion (C).
  • the ocular implant (100) may include first and second ends (E1, E2) that are separated from each other with the cut portion (C) therebetween.
  • the cut portion (C) can be formed along the short axis direction (Z2) of the inner annular edge (101) or the opening (OP) surrounded by the inner annular edge (101), and the first and second ends (E1, E2) separated from each other through the cut portion (C) can be joined toward each other along the long axis direction (Z1).
  • the first and second ends (E1, E2) separated through the cut portion (C) can be joined toward each other along the longitudinal direction (Z1) through a surgical hole (10) formed on the first and second ends (E1, E2) or a catch joint or hook joint as described below.
  • the first and second slits (154a, 154b, 155a, 155b) or the assembly slits (156a) forming the surgical hole (10) or the catch joint or hook joint can be arranged in multiple numbers along the longitudinal direction (Z1) along which the first and second ends (E1, E2) extend.
  • the pupil expansion part (105) in which the above-mentioned cut part (C) and the first and second ends (E1, E2) are formed is a structure in which the front curved surface (120) forms a thickness profile on the rear slope (110) based on the rear slope (110) inclined at a constant tilting angle ( ⁇ ) from the vertical plane (G) perpendicular to the front direction (Z3) (the pupil expansion part 105 is not a flat structure parallel to the vertical plane G perpendicular to the front direction Z3).
  • the major axis direction (Z1) and the minor axis direction (Z2) can be defined in the front direction (Z3), but in this specification, for the convenience of understanding, for example, the rear slope (110) is formed as a surface inclined at a constant tilting angle ( ⁇ ) so that the inner annular edge (101) is arranged in a forward position and the outer annular edge (102) is arranged in a backward position, and the inner annular edge (101) is arranged in a relatively forward position.
  • the pupil expansion portion (105) formed between the annular edge (101) and the outer annular edge (102) positioned relatively posteriorly may have a thickness profile so as to form a thickness that varies toward the front curved surface (120) formed on the posterior slope (110), but may generally have a shape that is inclined from the front to the back, and accordingly, the incision portion (C) may be formed along the short axis direction (Z2) so as to coincide with the long axis direction (Z1) and the short axis direction (Z2) defined in the frontal direction (Z3) on the pupil expansion portion (105), or the first and second ends (E1, E2) separated from each other through the incision portion (C) may not be joined along the long axis direction (Z1) through the surgical hole (10) or the catch joint or the hook joint, but the posterior slope (110) may be approximately perpendicular to the frontal direction (Z3) from the vertical plane (G).
  • the pupil expansion part (105) in which the incision part (C), the surgical hole (10), the catch joint or the hook joint, etc. are formed is projected onto a vertical plane (G) approximately perpendicular to the frontal direction (Z3) because it is inclined at a small angle of about 20 to 40 degrees
  • the directionality of the incision part (C), the surgical hole (10), the catch joint or the hook joint, etc. formed on the pupil expansion part (105) can be sufficiently described by the major axis direction (Z1) and the minor axis direction (Z2) defined in the frontal direction (Z3).
  • the major axis direction (Z1) and the minor axis direction (Z2) may mean the length direction and the width direction of the first and second ends (E1, E2) in relation to forming the first and second ends (E1, E2) or forming the incision (C), the surgical hole (10), the catch joint, or the hook joint on the first and second ends (E1, E2).
  • the pupil expansion portion (105) between the inner annular edge (101) and the outer annular edge (102) is formed in a biased position, with the oval of the inner annular edge (101) being biased toward the other side position, within the circular shape of the outer annular edge (102), so that one of the two sides along the short axis direction (Z2) of the inner annular edge (101) is formed with a wider width than the other side position.
  • the above-mentioned incision (C), the first and second ends (E1, E2) separated from each other through the above-mentioned incision (C), and the surgical hole (10) or the catch joint or the hook joint for connecting the first and second ends (E1, E2) to each other can be formed at the one-sided position formed with a relatively wide width along the short-axis direction (Z2), and for example, the one-sided position formed with a relatively wide width along the short-axis direction (Z2) can correspond to the center position (S) of the surgical procedure in the surgical procedure of the ocular implant (100).
  • the cut portion (C) and the first and second ends (E1, E2) separated from each other by the cut portion (C) can be formed across the pupil expansion portion (105) and the inner annular edge (101) defining one end of the pupil expansion portion (105) and the outer annular edge (102) defining the other end of the pupil expansion portion (105), and in this sense, it can be said that the cut portion (C) forms the first and second ends (E1, E2) separating the ocular implant (100) from each other.
  • positions on both sides along the short-axis direction (Z2) of the inner annular edge (101) can be formed with a relatively smaller curvature than positions on both sides along the long-axis direction (Z1) of the inner annular edge (101), and among the two positions, one position having a wider width can be selectively set as the center position (S) of the procedure, and at the center position (S) of the procedure corresponding to the one position formed with the relatively smaller curvature and wider width, a configuration such as the incision (C), the first and second ends (E1, E2), the procedure hole (10), the catch joint or the hook joint can be formed.
  • a first end (E1) of the ocular implant (100) is inserted through an incision (EBC) formed on the conjunctiva, and the first end (E1) is made to circle around the outer ring of the pupil while circling around the circumference of the outer ring of the pupil, and then returns to connect the first end (E1) drawn out through the incision (C) to the second end (E2) that remains and is not inserted through the incision (C), thereby permanently transplanting the ocular implant (100) that has circled around the outer ring of the pupil.
  • EBC incision
  • the first and second ends (E1, E2) can be fastened to each other by inserting a suture so as to pass through the surgical hole (10) formed in the first and second ends (E1, E2) and fastening the surgical holes (10) of the first and second ends (E1, E2) to each other through the knot of the suture.
  • at least one surgical hole (10) may be formed in each of the first and second ends (E1, E2), and in various embodiments of the present invention, a plurality of surgical holes (10) may be formed in each of the first and second ends (E1, E2).
  • a plurality of surgical holes (10) may be formed in the first and second ends (E1, E2) of the eye implant (100) or the pupil expansion part (105) forming the body of the eye implant (100), and a plurality of surgical holes (10) may be formed at regular intervals along the longitudinal direction (Z1) in each of the first and second ends (E1, E2).
  • the connection between the first and second ends (E1, E2) can be made through the optimized position of the hole for use (10) formed in the first and second ends (E1, E2), and for example, the recipient of the ocular implant (100) can selectively select the hole for use (10) at a position suitable for the shape and size of the individualized pupil of each recipient, and connect the first and second ends (E1, E2) to each other through the hole for use (10) at a position optimized for surrounding the outer ring of the pupil along the circumference of the pupil of each recipient.
  • the surgeon may select a surgical hole (10) at an optimized position to surround the outer ring of the pupil of the recipient, insert a suture through the selected surgical hole (10), and bind them to each other. If the distance between the surgical holes (10) on both sides that bind the first and second ends (E1, E2) to each other as the suture penetrates is set too far, the pupil dilatation (105) between the surgical holes (10) on both sides that bind the first and second ends (E1, E2) to each other may be distorted, which may adversely affect the coplanarity of the entire pupil dilatation (105), and the entire ocular implant (100) including the pupil dilatation (105) may not adhere to the sclera and an empty space may be formed, which may cause side effects.
  • an ocular implant (100) having the same specifications is formed through the same mold design, but a binding position optimized for surrounding the outer ring of the pupil of the recipient is selected from among a plurality of surgical holes (10) formed in the first and second ends (E1, E2) of the ocular implant (100) that go around the outer ring of the pupil so as to be optimized for the shape and size of the pupil that are differentially formed depending on the physical condition of each recipient, and a suture is passed through the surgical hole (10) of the selected binding position, and the first and second ends (E1, E2) of the pupil expansion part (105) that form the ocular implant (100) that goes around the pupil of the recipient or the body of the ocular implant (100) are bound to each other.
  • the surgeon can cut and remove the extra pupil dilatation portion (105) that remains excessively between the surgical holes (10) on both sides selected as the binding positions among the plurality of surgical holes (10) formed at the first and second ends (E1, E2) of the ocular implant (100).
  • the extra pupil dilatation portion (105) that remains between the surgical holes (10) on both sides selected as the binding positions tends to be distorted and deformed in response to the stress that tends to reduce the length according to the tensile stress of the suture inserted to penetrate the surgical holes (10) selected as the binding positions
  • the surgeon can remove the extra pupil dilatation portion (105) between the surgical holes (10) on both sides selected as the binding positions at the first and second ends (E1, E2).
  • the surgeon can refer to the plurality of surgical holes (10) formed at regular intervals at the first and second ends (E1, E2) and remove the plurality of surgical holes (10).
  • the cutting position can be set based on the position of the hole (10).
  • the circumferential length of the pupillary expansion part (105) forming the ocular implant (100) or the body of the ocular implant (100) may be preferably set to a size optimized for surrounding the outer ring of the pupil so that the transplanted pupillary expansion part (105) forms an appearance integrated with the individualized pupil of each recipient while not covering the pupil (or pupil) that provides the light entrance aperture, and for example, by cutting the pupillary expansion part (105) formed in a standardized size or a single size so as to form a circumferential length optimized for surrounding the outer ring of the individualized pupil of each recipient, the circumferential length optimized for surrounding the outer ring of the individualized pupil of each recipient, for example, the circumferential length optimized for circling the outer ring of the
  • the surgeon may refer to the positions of the surgical holes (10) formed at regular intervals in the first and second ends (E1, E2) of the eye implant (100) or the pupil expansion portion (105) forming the body of the eye implant (100), and cut at least a part of one end among the first and second ends (E1, E2) to provide an optimized circumferential length for each implant.
  • the circumference of the ocular implant (100) or pupillary expansion portion (105) optimized to surround the pupil of the recipient can be set through examination or measurement of the eye (EB), and the cutting position can be set from the end of at least one of the first and second ends (E1, E2) to form the set circumference of the pupillary expansion portion (105).
  • the cutting position can be set based on the positions of a plurality of surgical holes (10) formed at regular intervals along the longitudinal direction (Z1) in the first and second ends (E1, E2).
  • the plurality of surgical holes (10) formed in each of the first and second ends (E1, E2) can be formed at 0.5 mm intervals along the longitudinal direction (Z1).
  • the plurality of surgical holes (10) formed along the length of the longitudinal direction (Z1) or the first and second ends (E1, E2) can provide a binding position optimized for surrounding the outer ring of the pupil of each transplant recipient with an individualized shape and size, and can provide a reference or standard for setting a cutting position to form a circumference optimized for surrounding the outer ring of the pupil of the transplant recipient, for example, a circumference optimized for circling the outer ring of the pupil of the transplant recipient.
  • the surgical hole (10) forms an incision (EBC) in the conjunctiva on the sclera
  • a space securing device (not shown) can be inserted to secure a transplantation space for the ocular implant (100) between the sclera and the conjunctiva along the incision (EBC), and the ocular implant (100) can be pulled toward the transplantation space secured by the space securing device, so that the ocular implant (100) can be pulled into the transplantation space through the transplantation insertion device so that the ocular implant (100) goes around the outer ring of the pupil of the recipient.
  • the implant insertion device inserts the first end (E1) of the ocular implant (100) through the surgical hole (10) formed in the first end (E1) of the ocular implant (100) toward the implantation space secured along the outer ring of the pupil of the recipient, and the ocular implant (100) is inserted from the first end (E1) to which the implant insertion device is fitted along the circular motion forced by the implant insertion device (not shown) into the implantation space secured along the outer ring of the pupil, thereby being able to make a circular motion along the outer ring of the pupil.
  • the surgical hole (10) formed in the first end (E1) or the second end (E2) can provide physical interference with the implantation insertion device (not shown) for pulling the entire ocular implant (100), that is, a position through which the implantation insertion device (not shown) for pulling the ocular implant (100) passes, and for example, the implantation insertion device (not shown) fitted into the surgical hole (10) can follow the implantation insertion device (not shown) fitted into the surgical hole (10) and follow the implantation insertion device (not shown) from the surgical hole (10) fitted into the surgical hole (10) or the first end (E1) where the surgical hole (10) is formed so as to surround the outer ring of the pupil.
  • the surgical hole (10) may include a first surgical hole (11) for penetration of a suture and a second surgical hole (12) for physical interference with an implantation insertion device or penetration of an implantation insertion device, which provides a binding position between the first and second ends (E1, E2).
  • the first and second surgical holes (11, 12) can be formed with substantially the same shape and size, and depending on the selection of the surgeon, some of the surgical holes (10) can function as first surgical holes (11) for penetration of a suture, and some of the surgical holes (10) can function as second surgical holes (12) for penetration of an implantation insertion device (not shown), and a plurality of surgical holes (10) formed with the same shape along the length of the longitudinal direction (Z1) or the first and second ends (E1, E2) can provide relatively free position selection, and can function as the first and second surgical holes (11, 12) depending on the selection of the surgeon.
  • the surgical hole (10) may include a first surgical hole (11) formed with a relatively small diameter to accommodate a relatively thin strand of suture, and a second surgical hole (12) formed with a relatively large diameter to accommodate a relatively thick implantation insertion tool (not shown) for traction of the entire ocular implant (100).
  • the first and second surgical holes (11, 12) may be formed at different positions along the first and second ends (E1, E2), and the first surgical hole (11) for penetration of the suture may be formed at a position relatively close to the ends of the first and second ends (E1, E2) along the longitudinal direction (Z1) to provide a binding position for binding the first and second ends (E1, E2) to each other, so that no excessive extra ocular implant (100) or pupil expansion part (105) may be interposed between the first surgical holes (11) on both sides, and the second surgical hole (12) may be formed at a position relatively far from the ends of the first and second ends (E1, E2) along the longitudinal direction (Z1) to allow the ocular implant (100) to be pulled through an implantation insertion device (not shown) fitted into the second surgical hole (12), thereby preventing the first and second surgical holes (11) from intervening. It is possible to prevent damage to the second section (E1, E2).
  • the ocular implant (100) can be formed in a symmetrical shape with respect to the center (O) of the opening (OP), and for example, in one embodiment of the present invention, the pupil expansion part (105) forming the ocular implant (100) or the body of the ocular implant (100) can be formed in a symmetrical shape along the major axis direction (Z1) and the minor axis direction (Z2) crossing the center (O) of the opening (OP).
  • the pupil expansion part (105) forming the ocular implant (100) or the body of the ocular implant (100) can have a cut portion (C) formed along the minor axis direction (Z2), and a plurality of surgical holes (10) can be formed in the first and second ends (E1, E2) separated by the cut portion (C).
  • the plurality of treatment holes (10) may be arranged along the major axis direction (Z1) and may be symmetrically formed along the minor axis direction (Z2).
  • the plurality of treatment holes (10) formed in the first and second ends (E1, E2) separated from each other through the incision (C) along the minor axis direction (Z2) followed by the incision (C) may be symmetrically formed.
  • first and second surgical holes (11, 12) of different sizes can be formed symmetrically in the first and second ends (E1, E2), and the second surgical hole (12) fitted into the implantation insertion device is formed symmetrically in the first and second ends (E1, E2), so that the surgeon can perform the implantation of the ocular implant (100) through the implantation insertion device fitted into the second surgical hole (12) of either of the first and second ends (E1, E2).
  • the incision (C) may be formed along the short axis direction (Z2) of the opening (OP), and may be formed at any one position along the short axis direction (Z2) of the opening (OP), and a plurality of surgical holes (10) may be formed in the first and second ends (E1, E2) divided by the incision (C) formed at any one position along the short axis direction (Z2).
  • the position at which the incision (C) dividing the first and second ends (E1, E2) or the first and second ends (E1, E2) is formed may correspond to any one position along the short axis direction (Z2) of the opening (OP), and may correspond to a part of the ocular implant (100) extending parallel to the long axis direction (Z1) or a part of the pupil expansion part (105) forming the body of the ocular implant (100).
  • the inner annular edge (101) defining the opening (OP) or the opening (OP) formed at the center position of the ocular implant (100) may be formed in an elliptical shape having different major axis lengths (L1) and minor axis lengths (L2), and the outer annular edge (102) formed on the opposite side to the inner annular edge (101) may be formed in a circular shape to provide an attractive appearance, and thus, in one embodiment of the present invention, the pupil expansion portion (105) formed between the inner annular edge (101) and the outer annular edge (102) may be formed in a shape in which the elliptical inner annular edge (101) is formed inside the circular outer annular edge (102), and the pupil defined by the outer annular edge (102) and the inner annular edge (101) of different shapes
  • the expansion portion (105) can be formed with different widths at different angular positions with the central opening (OP) as the rotation center.
  • the pupil expansion portion (105) can be formed with the widest width at the 0 degree angular position (A1) where the incision portion (C) is formed, and can be formed with widths of the same degree at the remaining 90 degree angular positions (A3), 180 degree angular positions (A2), and 270 degree angular positions (A4).
  • the first and second ends (E1, E2) divided by the incision (C) or the incision (C) may correspond to the center position (S) of the procedure of the ocular implant (100), and for example, the first and second ends (E1, E2) may be joined toward each other by inserting a suture so as to pass through a plurality of procedure holes (10, for example, the first procedure hole 11) formed in the first and second ends (E1, E2), and the ocular implant (100) may be implanted along the outer ring of the pupil of the recipient by inserting a transplantation insertion device so as to pass through the procedure holes (10, for example, the second procedure hole 12) formed in the first and second ends (E1, E2).
  • a transplantation insertion device so as to pass through the procedure holes (10, for example, the second procedure hole 12) formed in the first and second ends (E1, E2).
  • the pupil expansion portion (105) forming the ocular implant (100) or the body of the ocular implant (100) so as to be formed with the widest width at any one position along the short axis direction (Z2) of the ellipse surrounded by the inner annular edge (101) or the inner annular edge (101), in other words, at any one position among the 0 degree angle position (A1) and the 180 degree angle position (A2) forming both sides along the short axis direction (Z2) with the center (O) of the opening (OP) as the rotation center, the position corresponding to the center position (S) of the procedure (for example, the 0 degree angle position A1) is formed with a relatively wide width, thereby providing ease of procedure.
  • the elliptical inner annular edge (101) is arranged inside the circular outer annular edge (102) so as to form the widest pupil dilatation portion (105) at a position corresponding to the center position (S) of the procedure (for example, 0 degree angle position A1).
  • the elliptical inner annular edge (101) may be arranged at a position offset toward the other side position so that a relatively wide width is secured at one of the two sides along the short axis direction (Z2).
  • the elliptical inner annular edge (101) defining the opening (OP) may be positioned at a biased position that is offset from the center position of the circular outer annular edge (102) along the short-axis direction (Z2) toward the other side position so that the width of one side position increases among the two sides.
  • a position corresponding to the center position (S) of the procedure may correspond to any one of the two positions along the short axis direction (Z2), and may correspond to one position having a relatively wide width among the two positions along the short axis direction (Z2), and an incision (C) and a hole (10) for the procedure may be formed at the one position corresponding to the center position (S) of the procedure, and a catch joint and a hook joint, etc. described below may also be formed at one position of the pupil expansion portion (105) along the short axis direction (Z2).
  • one side position can be formed with a relatively wide width and can form a portion with a relatively small curvature while extending approximately along the long axis direction (Z1), and in contrast, among the positions on both sides along the long axis direction (Z1) can be formed with a relatively narrow width and can form a portion with a relatively large curvature while extending approximately along the short axis direction (Z2).
  • the first and second ends (E1, E2) can be fastened to each other through a suture that is inserted so as to pass through a surgical hole (10) formed in the first and second ends (E1, E2), but in various embodiments of the present invention, the first and second ends (E1, E2) can form a hook connection or a hook connection in which one of the first and second ends (E1, E2) is inserted into the other to form a hook for each other, thereby preventing the first and second ends (E1, E2) from being separated from each other.
  • first and second ends (E1, E2) may be formed with first and second slits (154a, 154b, 155a, 155b) for fitting the second and first ends (E1, E2) corresponding to the opposite ends of the coupling, respectively, and the first and second ends (E1, E2) may be fitted to each other through the first and second slits (154a, 154b, 155a, 155b) formed in a complementary shape to each other, and once fitted, the first and second ends (E1, E2) may be prevented from being separated through the first and second slits (154a, 154b, 155a, 155b) formed complementarily, and the first and second ends (E1, E2) may be prevented from being separated through the first and second slits (154a, 154b, 155a, 155b) formed in a complementary shape to each other.
  • first and second ends (E1, E2) may be formed with first and second slits (154a, 154b, 155a, 155b) for
  • the first and second slits (154a, 154b, 155a, 155b) formed in the first and second ends (E1, E2), respectively may include a first portion (1541, 1551) extending along a major axis direction (Z1) in which the first and second ends (E1, E2) face each other with a cut portion (C) therebetween or a major axis direction (Z1) intersecting a minor axis direction (Z2) in which the cut portion (C) extends, and a second portion (1542, 1552) extending from the first portion (1541, 1551) along the minor axis direction (Z2) to the outside of the ocular implant (100) or the pupil expansion portion (105) of the ocular implant (100).
  • the second portions (1542, 1552) may be formed in complementary shapes, for example, the second portions (1542, 1552) of the first and second slits (154a, 154b, 155a, 155b) formed in the first and second ends (E1, E2) respectively may extend from the first portion (1541, 1551) along the major axis direction (Z1) in opposite directions along the minor axis direction (Z2), that is, may extend from the first portion (1541, 1551) toward the inner annular edge (101) and the outer annular edge (102) formed on opposite sides, and may open toward the outside of the pupil expansion portion (105).
  • first and second slits (154a, 154b, 155a, 155b) of the first and second ends (E1, E2) fitted to each other can prevent separation from each other while the second portions (1542, 1552) formed in a complementary shape among the first and second slits (154a, 154b, 155a, 155b) function as a catch or hook against separation from each other.
  • the first and second slits (154a, 154b, 155a, 155b) may extend from a first portion (1541, 1551) extending along the major axis direction (Z1) toward the outside of the pupil dilatation portion (105) while being perpendicular to the first portion (1541, 1551) along the minor axis direction (Z2) so as to open toward the outside of the pupil dilatation portion (105), or may extend from the first portion (1541, 1551) extending along the major axis direction (Z1) toward the outside of the pupil dilatation portion (105) along an oblique direction simultaneously following the major axis direction (Z1) and the minor axis direction (Z2) so as to open toward the outside of the pupil dilatation portion (105).
  • At least one of the first and second slits (154a, 154b, 155a, 155b) formed in the first and second ends (E1, E2) may be arranged in a plurality along the longitudinal direction (Z1) or the length of the first and second ends (E1, E2).
  • the longitudinal direction of the first and second ends (E1, E2) in which the plurality of first and second slits (154a, 154b, 155a, 155b) or the plurality of surgical holes (10) are arranged may correspond to the longitudinal direction (Z1) that is perpendicular to the short-axis direction (Z2) in which the cut portion (C) separating the first and second ends (E1, E2) extends.
  • At least one of the first and second slits (154a, 154b, 155a, 155b) arranged in a plurality of positions can be adjusted to form a circumferential length of the ocular implant (100) or the pupil expansion portion (105) of the ocular implant (100) optimized for surrounding the pupil of the eye by adjusting the binding position between the first and second slits (154a, 154b, 155a, 155b), thereby binding the first and second ends (E1, E2) to each other through the first and second slits (154a, 154b, 155a, 155b) selected from among the plurality of first and second slits (154a, 154b, 155a, 155b) arranged along the length of the first and second ends (E1, E2).
  • the cut portion (C) may be formed along the short-axis direction (Z2) of the inner annular edge (101), the first and second ends (E1, E2) may be adjacent to each other along the long-axis direction (Z1) of the inner annular edge (101), and one of the first and second slits (154a, 154b, 155a, 155b) may include an array of first slits (154a, 155a) or an array of second slits (154b, 155b) formed in multiple numbers on the first end (E1) or the second end (E2) along the long-axis direction (Z1), and the other may be formed as a single second slit (154b, 155b) or first slit (154a, 155a).
  • an assembly slit (156a) in order to form a catch joint or a hook joint that connects the first and second ends (E1, E2), an assembly slit (156a) may be formed in one of the first and second ends (E1, E2), and an assembly hole (156b) into which the assembly slit (156a) is fitted may be formed in the other end.
  • an assembly slit (156a) may be formed in the first end (E1), and an assembly hole (156b) into which the assembly slit (156a) is fitted may be formed in the second end (E2).
  • the second end (E2) side assembly hole (156b) into which the first end (E1) side assembly slit (156a) is fitted is formed in a closed form that is isolated from the outside of the second end (E2) without being opened toward the outside of the second end (E2), so that in consideration of the assembling property of the fitting of the first end (E1) side assembly slit (156a), an assembly guide portion (158) may be formed at the end of the first end (E1), and the assembly guide portion (158) includes a rear end (158c) with a relatively wide width and a front end protrusion (158a) formed with a relatively narrow width along the assembly direction or the major axis direction (Z1), and simultaneously follows the major axis direction (Z1) and the minor axis direction (Z2) so as to connect the differential widths of the rear end (158c) with a wide width and the front end protrusion (158a) with a narrow width.
  • the rear end (158c) forming the boundary of the assembly guide portion (158) may mean the boundary of the assembly guide portion (158) having a wide width corresponding to the full width (W0) of the pupil expansion portion (105), and at this time, the full width (W0) of the pupil expansion portion (105) means the width of the complete pupil expansion portion (105) in which the assembly slit (156a) introduced from the inner annular edge (101) and/or the outer annular edge (102) such as the assembly slit (156a) is not formed, and may mean, for example, the pupil expansion portion (105) having a wider width than the bottleneck (W1) having a narrow width limited by the assembly slit (156a).
  • an assembly guide portion (158) may be formed on the front side of the first end (E1) along the assembly direction or longitudinal direction (Z1) of the first and second ends (E1, E2), and an assembly slit (156a) may be formed on the rear side of the first end (E1).
  • a first end (E1) having a relatively wide width may be interposed between the front-side assembly guide portion (158) and the rear-side assembly slit (156a).
  • the relatively wide first end (E1) interposed between the assembly induction member (158) and the assembly slit (156a) may mean the full width (W0) of the pupil expansion member (105) having a relatively wide complete width in which the assembly slit (156a) introduced from the inner annular edge (101) and/or the outer annular edge (102) is not formed.
  • the assembly slit (156a) may be formed in a shape that is introduced toward the inside of the pupil expansion portion (105) between the inner annular edge (101) and the outer annular edge (102) along the short-axis direction (Z2), and in this way, the width of the bottleneck (W1) that forms the minimum width while being introduced from the inner annular edge (101) and the outer annular edge (102) on both sides defining the pupil expansion portion (105) may be equal to or smaller than the width (W2) of the assembly hole (156b) on the second end (E2) side.
  • the assembly slits (156a) on the first end (E1) side can be arranged in multiple numbers along the longitudinal direction (Z1) or the length of the first end (E1), and for example, in one embodiment of the present invention, through the arrangement of the assembly slits (156a) formed along the longitudinal direction (Z1) or the length of the first end (E1), the fastening position between the first and second ends (E1, E2) can be varied to form a circumferential length optimized for surrounding the pupil of the recipient.
  • the assembly guide member (158) on the first end (E1) side can align the fastening positions between the first and second ends (E1, E2) with each other, while guiding the assembly slit (156a) formed at the rear of the assembly guide member (158) on the first end (E1) side toward the assembly hole (156b) on the second end (E2) side.
  • the width of the projection (158a) of the front end formed on the assembly guide portion (158) of the first end (E1) side can be formed to be narrower than the width (W2) of the assembly hole (156b) of the second end (E2) side, and when the projection (158a) of the front end of the first end (E1) side is fitted into the assembly hole (156b) of the second end (E2) side, the fastening positions of the first and second ends (E1, E2) can be aligned with respect to each other, and when the operator of the ocular implant (100) pulls the projection (158a) of the front end of the first end (E1) side fitted into the assembly hole (156b) of the second end (E2) side toward the second end (E2), the first end (E1) side assembly guide portion (158) of the first end (E1) side having a relatively wide width is connected to the variable width portion (158b) of the first end (E1) side assembly guide portion.
  • the end portion (E1, the full width W0 of the first end portion E1) can be guided toward the assembly hole (156b) on the second end portion (E2) side, and when the assembly hole (156b) on the second end portion (E2) side is fitted into the bottleneck (W1) of the assembly slit (156a) connected to the first end portion (E1, the full width W0 of the first end portion E1) with a wide width, the first and second ends (E1, E2) can be prevented from moving away from each other, and for example, when the first end portion (E1, the full width W0 of the first end portion E1) with a relatively wide width functions as a catch or hook before and after the bottleneck (W1) of the assembly slit (156a) on the first end (E1) side fitted into the assembly hole (156b) on the second end (E2) side, the first and second ends (E1, E2) can be prevented from moving away from each other. there is.
  • the assembly guide part (158) is configured to induce a catch joint or hook joint between the bottle neck (W1) of the assembly slit (156a) and the assembly hole (156b) at the rear by passing through the assembly guide part (158) at the front along the assembly direction or the longitudinal direction (Z1) and the assembly hole (156b) in which the relatively thick first end (E1, the overall width W0 of the first end E1) is formed with a relatively narrow width.
  • the assembly guide part (158) is configured to induce a catch joint or hook joint between the bottle neck (W1) of the assembly slit (156a) at the rear and the assembly hole (156b) after the first and second ends (E1, E2) are connected to each other through the catch joint or hook joint, that is, after the bottle neck (W1) of the assembly slit (156a) of the first end (E1) is fitted into the assembly hole (156b) of the second end (E2), by removing the assembly guide part (158) that has served its usefulness, for example, the second By removing the assembly guide member (158) that overlaps and forms additional thickness on the end portion (E2), adverse effects on the surrounding ocular (EB) tissue can be eliminated and deformation of the ocular implant (100) can be prevented.
  • EB ocular
  • a cutting line (CL) may be formed along a rear boundary corresponding to the rear end (158c) of the assembly guide portion (158) along the assembly direction or the longitudinal direction (Z1), and after the first and second ends (E1, E2) are fastened to each other through a catch joint or a hook joint, the assembly guide portion (158) may be separated and removed along the cutting line (CL).
  • the cutting line (CL) may be formed between the front assembly guide portion (158) and the rear assembly slit (156a), and more specifically, may be formed along the boundary (the rear boundary of the assembly guide portion 158 forming the rear end 158c of the assembly guide portion 158) between the front assembly guide portion (158) and the relatively wide first end portion (E1, the overall width W0 of the first end portion E1) formed between the front assembly guide portion (158) and the rear assembly slit (156a).
  • the cutting line (CL) may include a plurality of perforations formed along the cutting line (CL) or may include an indicator line indicating a cutting position in a form other than perforations.
  • the cutting line (CL) may be formed along the short axis direction (Z2) parallel to the cut portion (C).
  • the first and second ends (E1, E2) separated from each other with the incision (C) therebetween are connected to each other by using a surgical hole (10) formed in the first and second ends (E1, E2) and a suture thread passing through the first and second ends (E1, E2), or by using a first and second slit (154a, 154b, 155a, 155b) formed in the first and second ends (E1, E2) and fitting the first and second ends (E1, E2) to each other through the first and second slits (154a, 154b, 155a, 155b), or by using an assembly slit (156a) and an assembly hole (156b) formed in the first and second ends (E1, E2).
  • the first and second ends (E1, E2) can be connected to each other by the assembly slit (156a) on the end (E1) side being fitted into the assembly hole (156b) on the second end (E2) side.
  • the first and second ends (E1, E2) corresponding to the fastening targets may be fastened to each other while facing each other along the assembly direction or the longitudinal direction (Z1) without overlapping each other, or the fastening may be formed while the first and second ends (E1, E2) overlap each other. As shown in FIGS.
  • first and second slits (154a, 154b, 155a, 155b) are formed in the first and second ends (E1, E2) and are fitted to each other, or in a structure where the assembly slits (156a) and the assembly holes (156b) are formed in the first and second ends (E1, E2) and are fitted to each other, the first and second ends (E1, E2) overlap each other to form an extra thickness.
  • the extra thickness formed in this way can locally form extra thickness along the circumferential direction of the eye implant (100) or the pupil expansion portion (105) forming the body of the eye implant (100) to force stress or deformation, etc., from this consideration, among the first and second ends (E1, E2), the first and second slits (154a, 154b, 155a, 155b) that are fitted against each other to bind the first and second ends (E1, E2) toward each other and the cut portion (C) are overlapped at a position where the first and second ends (E1, E2) overlap each other, or between the bottleneck (W1) of the assembly slit (156a) and the assembly hole (156b) and the cut portion (C) that are fitted against each other to bind the first and second ends (E1, E2) toward each other, the first and second ends (E1, E2) overlap each other.
  • the first and second ends (E1, E2) that overlap each other are formed with a relatively thin thickness, so that a uniform thickness can be formed over the entire circumference surrounding the outer ring of the pupil of the recipient in the ocular implant (100) in which the transplantation is completed or in the ocular implant (100) in which the fastening between the first and second ends (E1, E2) is completed.
  • a thin section formed with a relatively thin thickness can be formed around the first and second slits (154a, 154b, 155a, 155b) on the first and second ends (E1, E2) so as not to form additional excess thickness from overlapping the first and second ends (E1, E2), and the thin sections of the first and second ends (E1, E2) can form a normal thickness of the ocular implant (100) by overlapping each other.
  • the catch joint or hook joint that connects the first and second ends (E1, E2) separated from each other through the cut portion (C) toward each other can be formed at a position of one end formed with a relatively wide width among the positions on both sides along the short-axis direction (Z2), and can be formed at a position of one end extending along the generally long-axis direction (Z1) with a relatively small curvature, thereby making it relatively easy to connect the first and second ends (E1, E2) in the procedure of the ocular implant (100), and this position of one end can form a central position (S) of the procedure in the procedure of the implant.
  • the center position (S) of the implant procedure is described as a one-sided position formed with a relatively wide width while the elliptical profile of the inner annular edge (101) is deflected to the other side within the circular profile of the outer annular edge (102) among the one-sided position and the other side position of the pupil expansion portion (105) forming the two-sided positions along the short-axis direction (Z2), but in the embodiment illustrated in the drawings attached to this specification, the center position (S) of the procedure may be selectively formed at any one of the one-sided position (0 degree angle position A1) and the other side position (180 degree angle position A2) that are formed at a position symmetrical to each other without the elliptical profile of the inner annular edge (101) being deflected to either one side position or the other side position along the short-axis direction (Z2) and have substantially the same width, and in one embodiment of the present invention, the one-sided position forming the center position (S) of the procedure is By selecting from the two positions along the direction (Z
  • the arrangement of these configurations may be arranged along the length of the first and second ends (E1, E2), and for example, may be arranged along the length of the first and second ends (E1, E2) forming a part of the circumference along the circumference direction of the pupil dilatation part (105), so that through this specification, it is meant that these arrangements are arranged along the longitudinal direction (Z1) of the pupil dilatation part (105). This could mean that they are arranged along the circumferential direction.
  • FIG. 12 is a drawing showing a modified embodiment of the ocular implant illustrated in FIG. 4.
  • the outer annular edge (102) may be formed with a circular profile, and an inner annular edge (101) of a circular profile may be formed inside the circular profile of the outer annular edge (102).
  • the inner annular edge (101) and the outer annular edge (102) may surround the opening (OP) with the same circular profile, for example, may surround the opening (OP) in a concentric shape with the center (O) of the opening (OP) as the centrifugal point.
  • the inner annular edge (101) may be formed as a circle having a major axis length (L1) along the direction in which a pair of eyes of the recipient face each other and a minor axis length (L2) perpendicularly intersecting the major axis length (L1) and the minor axis length (L2) which are equal to each other, and the convenience of the procedure may be improved by forming a circular profile having the major axis length (L1) and the minor axis length (L2) as equal lengths so that alignment with the pupil of the recipient is not required, and the convenience of the processing process for forming the ocular implant (100) may be improved by forming the outer annular edge (102) and the inner annular edge (101) in a concentric shape with the center (O) of the opening (OP) as the centrifuge.
  • FIG. 13 is a drawing showing a modified embodiment of the ocular implant illustrated in FIG. 6.
  • the adaptive stretching portions (1511, 1512) can provide longitudinal stretching along the perimeter of the inner annular edge (101) and the outer annular edge (102) so as to adaptively change to the shape and size of the pupil of each recipient.
  • the adaptive stretching portion (1511) of the inner annular edge (101) can include a plurality of slits (1511s) formed spaced apart from each other along the perimeter of the inner annular edge (101)
  • the adaptive stretching portion (1512) of the outer annular edge (102) can include a plurality of slits (1512s) formed spaced apart from each other along the perimeter of the outer annular edge (102).
  • the width (d1) of the slit (1511s) forming the adaptive stretching portion (1511) of the inner annular edge (101) can be formed along the depth direction from the inner annular edge (101) toward the outer annular edge (102), and the width (d2) of the slit (1512s) forming the adaptive stretching portion (1512) of the outer annular edge (102) can be formed along the depth direction from the outer annular edge (102) toward the inner annular edge (101).
  • the width (d2) of the slit (1152s) forming the adaptive stretching portion (1152) of the outer annular edge (102) may be formed smaller than the width (d1) of the slit (1151s) forming the adaptive stretching portion (1151) of the inner annular edge (101).
  • the size of the width (d1, d2) of the slits (1151s, 1152s) forming each of the adaptive stretching portions (1151, 1152) may be adjusted so that the range of length elongation provided by the adaptive stretching portion (1151) of the inner annular edge (101) is wider than the range of length elongation provided by the adaptive stretching portion (1152) of the outer annular edge (102).
  • the adaptive elastic portions (1511, 1512) can be adjusted in size of the width (d1, d2) of the slits (1151s, 1152s) forming each adaptive elastic portion (1151, 1152) so that the range of longitudinal expansion of the inner annular edge (101) surrounding the pupil at a relatively close position is wider than the range of longitudinal expansion of the outer annular edge (102) surrounding the pupil at a relatively far position, so that the adaptive elastic portions (1511, 1512) can be adaptively deformed to the shape and size of the pupil of each recipient.
  • the adaptive elastic portion (1511, 1512) may be formed along the perimeter of either the inner annular edge (101) or the outer annular edge (102), or may be formed on both sides along the perimeters of the inner annular edge (101) and the outer annular edge (102).
  • FIG. 14 is a drawing for explaining a configuration in which different mechanisms are combined to connect first and second ends (E1, E2) separated from each other through a cut portion (C) toward each other in one embodiment of the present invention.
  • an ocular implant (100) illustrated in the drawing may be formed in a composite manner with a surgical hole (10) and a catch joint or a hook joint.
  • an ocular implant (100) according to one embodiment of the present invention may have first and second slits (154a, 154b) formed on the sides of each of the first and second ends (E1, E2) as a hook connection or a slit joint, together with a surgical hole (10), and referring to FIG. 14 and FIG.
  • an ocular implant (100) may have an assembly slit (156a) and an assembly hole (156b) formed on the sides of the first and second ends (E1, E2) as a hook connection or a slit joint, together with a surgical hole (10).
  • the binding force between the first and second ends (E1, E2) can be increased, and for example, if it is determined by the surgeon's judgment that sufficient binding force between the first and second ends (E1, E2) can be formed only with the catch-joint or the hook-joint, the suture passing through the surgical hole (10) can be omitted, and in contrast, the first and second ends (E1, E2) temporarily fixed by the catch-joint or the hook-joint
  • the bonding force between the first and second ends (E1, E2) can be reinforced and the first and second ends (E1, E2) can be
  • the surgical hole (10) formed in combination with a catch joint or a hook joint provides a bonding position between the first and second ends (E1, E2), and may include a first surgical hole (11) for the penetration of a suture and a second surgical hole (12) for physical interference with an implantation insertion device or the penetration of an implantation insertion device.
  • the first and second ends (E1, E2) may be arranged to overlap each other and a bioadhesive may be applied between the first and second ends (E1, E2), or the first and second ends (E1, E2) may be arranged to overlap each other and one of the first and second ends (E1, E2) may be welded to the other end by heat melting, and in the fusion bonding of the first and second ends (E1, E2), the first and second ends (E1, E2) that have become adhesive through high heat input may be pressed toward each other to bond these first and second ends (E1, E2) to each other.
  • various mechanisms for fastening the first and second ends (E1, E2) to each other may be formed alone or in combinations of different mechanisms, and for example, if a bonding method such as a bioadhesive or heat fusion is applied as described above, the surgical hole (10) or the first and second slits (154a, 154b) for hook coupling or hook coupling, the assembly slit (156a) or the assembly hole (156b) may not be formed on the first and second ends (E1, E2).
  • an ocular implant (100) is configured such that a pupil dilation (105) between an inner annular edge (101) and an outer annular edge (102) is formed with a wider width at one of the two positions along the short axis of the inner annular edge (101) than at the other position, such that an elliptical or circular profile of the inner annular edge (101) can be formed at a biased position that is biased toward the other position within the circular profile of the outer annular edge (102), and accordingly, one position of the pupil dilation (105) formed with a relatively wider width at one of the two positions along the short axis of the elliptical or circular shape of the inner annular edge (101) can provide a central position (O) of the procedure.
  • the elliptical or circular profile of the inner annular edge (101) within the circular profile of the outer annular edge (102) may be formed with equal widths without being biased toward either one or the other of the two positions along the short axis direction, and this may cause inconvenience in the procedure as the practitioner must confirm a position with a relatively wide width along the short axis direction in order to take the center position (O) of the procedure of the ocular implant (100), and in the molding of the ocular implant (100), this may cause inconvenience in handling due to lack of rigidity at one or the other position with a relatively thin width in a shape biased toward either one or the other position.
  • the ocular implant (100) may be formed so that the one-sided position or the other-sided position has an equal width without being biased toward either one-sided position or the other-sided position along the short-axis direction, and in other words, in one embodiment of the present invention, the inner annular edge (101) may be formed at a symmetrical position so that the two-sided positions are formed evenly along the short-axis direction within the circular profile of the outer annular edge (102).
  • the inner annular edge (101) may be formed as an oval or circular profile, and the major axis or minor axis of the inner annular edge (101) may be defined in a structure where the major axis length (L1) and the minor axis length (L2) are different from each other, as in an oval, and in a circle where the major axis length (L1) and the minor axis length (L2) are equal to each other, the major axis may mean a direction in which a pair of eyes of the implanter face each other, and the minor axis may mean a direction intersecting the major axis.
  • FIG. 15 is a drawing showing a modified embodiment of the ocular implant (100) illustrated in FIG. 9.
  • the surgical holes (10) formed on the sides of the first and second ends (E1, E2) separated from each other through the incision (C) can be formed in an asymmetrical number, and accordingly, a surgeon performing the ocular implant (100) can confirm the orientation of the ocular implant (100).
  • the ocular implant (100) in the procedure of the ocular implant (100), may be pulled along the outer ring of the pupil through a second procedure hole (12) fitted into a transplant insertion tool for inserting the ocular implant (100) so as to travel along the outer ring of the pupil of the recipient.
  • the direction in which the ocular implant (100) is pulled along the outer ring of the pupil through the transplant insertion tool may be set in advance from the shape design of the transplant insertion tool.
  • the orientation of the ocular implant (100) of the present invention is aligned to the correct orientation by a surgeon who recognizes the orientation of the ocular implant (100), it is necessary to insert the transplant insertion tool into the second procedure hole (12) and operate the transplant insertion tool so as to travel along the outer ring of the pupil of the recipient.
  • the ocular implant (100) can be formed of a soft material such as silicone that can be flexibly and adaptively deformed on the ocular (EB) tissue and is harmless to the ocular (EB) tissue, the anterior curved surface (120) and the posterior sloped surface (110) of the ocular implant (100) can be flipped over to each other, and even if the anterior curved surface (120) and the posterior sloped surface (110) of the ocular implant (100) are flipped over in this way, for example, even if the ocular implant (100) is flipped over so that the anterior curved surface (120) and the posterior sloped surface (110) of the ocular implant (100) are flipped over to each other, the anterior curved surface (120), not the posterior sloped surface (110), is arranged toward the eye (EB), and the posterior sloped surface (110) is arranged toward the outside world opposite to the eye (EB), the ocular implant (100) can be Orientation errors may be difficult for
  • the ocular implant (100) is formed with a number of operation holes (10) that are asymmetrical to each other on the first and second ends (E1, E2) that are separated from each other through the incision (C), for example, the number of operation holes (10) formed on the first and second ends (E1, E2) is formed differently from each other, or the number of operation holes (10) formed on the first and second ends (E1, E2) is formed as an even number on one end side and as an odd number on the other end side, so that when a surgeon performing the ocular implant (100) confirms which end side the implantation insertion device is inserted into among the first and second ends (E1, E2) from the shape design of the implantation insertion device, if a normal number of operation holes (10) or a normal odd number or a normal even number of operation holes (10) are not confirmed, the corresponding It can be recognized that the ocular implant (100) has an anterior curve (120) formed to face the outer world (OS) opposite to the eyeball (EB
  • the orientation of the ocular implant (100) can be confirmed through an asymmetrical design in which the number of holes (10) for surgery formed on the first and second ends (E1, E2) separated from each other through the incision (C) is different, or the number of holes (10) for surgery formed on the first and second ends (E1, E2) is formed as an even or odd number.
  • the present invention can be applied to the medical industry related to the manufacture of ocular implants for the treatment of transplant patients and the production of instruments for the treatment.

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  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
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  • Ophthalmology & Optometry (AREA)
  • Transplantation (AREA)
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  • Surgery (AREA)
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  • Inorganic Chemistry (AREA)
  • Prostheses (AREA)

Abstract

La présente invention concerne un implant oculaire. La présente invention peut fournir un implant oculaire qui doit être implanté de manière permanente dans le globe oculaire pour éliminer l'inconvénient de la fixation et du détachement. L'implant oculaire peut former un bel aspect intégré à la pupille sans bloquer une ouverture d'entrée de lumière.
PCT/KR2024/006877 2023-06-27 2024-05-21 Implant oculaire Ceased WO2025005478A1 (fr)

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CN202480029467.0A CN121038751A (zh) 2023-06-27 2024-05-21 一种眼球植入体

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KR20230082264 2023-06-27
KR20230082261 2023-06-27
KR10-2023-0082260 2023-06-27
KR20230082262 2023-06-27
KR20230082260 2023-06-27
KR10-2023-0082261 2023-06-27
KR10-2023-0082262 2023-06-27
KR20230082263 2023-06-27
KR10-2023-0082263 2023-06-27
KR10-2023-0082264 2023-06-27
KR1020240028125A KR20250000849A (ko) 2023-06-27 2024-02-27 안구용 임플란트
KR10-2024-0028125 2024-02-27
KR10-2024-0028124 2024-02-27
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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6565584B1 (en) * 1992-04-10 2003-05-20 Addition Technology, Inc. Device and method for inserting a biocompatible material into the corneal stroma
KR100541058B1 (ko) * 1997-10-08 2006-01-10 라스 홀딩 코포레이션 노안 및 다른 시각 장애의 치료를 위해 분할된 공막밴드
JP2008517671A (ja) * 2004-10-22 2008-05-29 アキュフォーカス・インコーポレーテッド 光学装置を目の軸に位置合わせするためのシステム及び方法
KR20160085870A (ko) * 2013-11-14 2016-07-18 아이드 파마 안과용 장치
WO2016160456A1 (fr) * 2015-04-03 2016-10-06 The Regents Of The University Of Colorado, A Body Corporate Dispositifs et procédés de stabilisation d'une capsule de lentille oculaire et de prévention de rotation d'implant de lentille intraoculaire artificielle suite à une chirurgie de la cataracte
US20170000644A1 (en) * 2008-11-20 2017-01-05 Insight Innovations, Llc Biocompatible Biodegradable Intraocular Implant System
KR101713055B1 (ko) * 2016-10-27 2017-03-07 이동호 안구의 미용을 위한 눈동자 확대부재 및 그 확대부재를 사용한 미용성형시술방법 및 그 시술기구

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6565584B1 (en) * 1992-04-10 2003-05-20 Addition Technology, Inc. Device and method for inserting a biocompatible material into the corneal stroma
KR100541058B1 (ko) * 1997-10-08 2006-01-10 라스 홀딩 코포레이션 노안 및 다른 시각 장애의 치료를 위해 분할된 공막밴드
JP2008517671A (ja) * 2004-10-22 2008-05-29 アキュフォーカス・インコーポレーテッド 光学装置を目の軸に位置合わせするためのシステム及び方法
US20170000644A1 (en) * 2008-11-20 2017-01-05 Insight Innovations, Llc Biocompatible Biodegradable Intraocular Implant System
KR20160085870A (ko) * 2013-11-14 2016-07-18 아이드 파마 안과용 장치
WO2016160456A1 (fr) * 2015-04-03 2016-10-06 The Regents Of The University Of Colorado, A Body Corporate Dispositifs et procédés de stabilisation d'une capsule de lentille oculaire et de prévention de rotation d'implant de lentille intraoculaire artificielle suite à une chirurgie de la cataracte
KR101713055B1 (ko) * 2016-10-27 2017-03-07 이동호 안구의 미용을 위한 눈동자 확대부재 및 그 확대부재를 사용한 미용성형시술방법 및 그 시술기구

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