WO2025174896A1 - Profondeur de champ étendue et haute définition obtenue par modification subsurfacique in vivo d'une lentille intraoculaire - Google Patents

Profondeur de champ étendue et haute définition obtenue par modification subsurfacique in vivo d'une lentille intraoculaire

Info

Publication number
WO2025174896A1
WO2025174896A1 PCT/US2025/015604 US2025015604W WO2025174896A1 WO 2025174896 A1 WO2025174896 A1 WO 2025174896A1 US 2025015604 W US2025015604 W US 2025015604W WO 2025174896 A1 WO2025174896 A1 WO 2025174896A1
Authority
WO
WIPO (PCT)
Prior art keywords
lens
iol
laser
modification
eye
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
PCT/US2025/015604
Other languages
English (en)
Inventor
Matthew SCHUSTER
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Z Optics Inc
Original Assignee
Z Optics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Z Optics Inc filed Critical Z Optics Inc
Publication of WO2025174896A1 publication Critical patent/WO2025174896A1/fr
Pending legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/107—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for determining the shape or measuring the curvature of the cornea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/103—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for determining refraction, e.g. refractometers, skiascopes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/103—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for determining refraction, e.g. refractometers, skiascopes
    • A61B3/1035—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for determining refraction, e.g. refractometers, skiascopes for measuring astigmatism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/11—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for measuring interpupillary distance or diameter of pupils
    • A61B3/112—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for measuring interpupillary distance or diameter of pupils for measuring diameter of pupils
    • G—PHYSICS
    • G02—OPTICS
    • G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
    • G02C7/00—Optical parts
    • G02C7/02—Lenses; Lens systems ; Methods of designing lenses
    • G02C7/04—Contact lenses for the eyes
    • G—PHYSICS
    • G02—OPTICS
    • G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
    • G02C7/00—Optical parts
    • G02C7/16—Shades; shields; Obturators, e.g. with pinhole, with slot
    • G02C7/165—Shades; shields; Obturators, e.g. with pinhole, with slot with stenopaeic apertures

Definitions

  • Conventional optical lens solutions for extending depth of focus while eliminating common drawbacks include diffractive and refractive multifocal lenses having discrete zones.
  • Other conventional solutions include aspheric lenses with a power profile that varies over the radius of the lens and small aperture (e.g., pinhole) lenses.
  • a lens such as an IOL, that includes at least one subsurface modification (comprising a modification to at least a portion of the internal structure of the IOL such as a modification to a plane or volume of the IOL) wherein the modification is achieved in vivo.
  • the lens can include such a subsurface modification as well as an optional external surface feature (such as a shape change or contour on the external surface) on an anterior and/or posterior external surface of the lens.
  • the subsurface modification is configured to achieve a desired optical effect on light that passes therethrough or otherwise interacts with the subsurface modification, such as to diffuse light, homogenize light, or redirect light for example.
  • a method of forming a customized lens comprising: measuring at least one optical characteristic of a patient including: obtaining a biometry of an eye of the patient; obtaining an emmetropic power of the eye and an emmetropic power correction; obtaining a pupillary mobility of the eye; obtaining a pupil size of the eye; obtaining a low contrast sensitivity of the eye; obtaining a corneal aberration and a corneal topography of the eye; identifying at least one target specification of the lens based on the at least one optical characteristic; providing a lens; and using a laser to modify an aspect of the lens to achieve the at least one target specification.
  • the laser forms a virtual aperture in the lens, wherein the virtual aperture surrounds an optical zone of the lens.
  • Figures 1A, IB, and 1C illustrates an overall structure of an example
  • Figure 2 shows a schematic representation of a laser system that is configured to interact with a lens such as in vivo.
  • Figure 3 shows a schematic representation of a portion of the IOL.
  • Figure 4 shows a schematic representation of a portion of the IOL.
  • Figure 5-7 each show a side, schematic representations of a lens having a front surface and a back or rear surface.
  • Figures 1A-1C illustrate a non-limiting example of an example lens comprising an intraocular lens (IOL.)
  • the lens can vary in configuration and type and can be, for example, an intraocular lens, a contact lens, or any other type of lens.
  • Figure 1 A shows a front view of the IOL wherein the front view may be an anterior view.
  • Figure IB shows a back view of the IOL wherein the back view may be a posterior view.
  • Figure 1C shows a side view of the IOL.
  • the IOL includes a central optical zone 46 (with back side 46b) that provides correction of defocus, astigmatism, and any other correction required of the lens such as spherical aberration.
  • the central optical zone diameter is smaller than that of a traditional IOL. This leads to a smaller central thickness which in turn makes the IOL easier to implant and allows a smaller corneal incision during surgery, such as an incision on the order of 2.2 mm.
  • the central optical zone can achieve variable transmissivity of light.
  • the IOL optionally includes a virtual aperture 48 that is positioned further peripherally outward relative to the center location of the central optical zone 46.
  • the construction and arrangement of the virtual aperture enable optical rays which intersect the virtual aperture to be widely scattered across a location such as a retina, causing the light to be virtually prevented from reaching detectable levels on the retina.
  • the virtual aperture helps remove monochromatic and chromatic aberrations, yielding high-definition retinal images.
  • the virtual aperture is not necessarily an aperture that blocks rays, but the optical effect is nearly the same on central vision.
  • the virtual aperture can be achieved via a surface modification, subsurface modification, or structure added to or positioned relative to the IOL, such as a mask structure.
  • the mask structure can be a ring-shaped structure or any ring-shaped mask that occludes at least a portion of light from passing through the IOL.
  • a modification of the lens (such as the subsurface modification) can occur at least partially pursuant to an in vivo process such as while the lens is implanted in an eye.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • General Physics & Mathematics (AREA)
  • Prostheses (AREA)

Abstract

L'invention concerne une lentille, telle qu'une LIO, comprenant au moins une modification subsurfacique (comprenant une modification d'au moins une partie de la structure interne de la LIO telle qu'une modification d'un plan ou d'un volume de la LIO), la modification étant obtenue in vivo. La lentille peut comprendre une caractéristique de surface externe (telle qu'un changement de forme ou un contour sur la surface externe) sur une surface externe antérieure et/ou postérieure de la lentille. La modification subsurfacique permet d'obtenir un effet optique souhaité sur la lumière qui la traverse, de manière à diffuser la lumière, homogénéiser la lumière ou rediriger la lumière.
PCT/US2025/015604 2024-02-14 2025-02-12 Profondeur de champ étendue et haute définition obtenue par modification subsurfacique in vivo d'une lentille intraoculaire Pending WO2025174896A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US202463553491P 2024-02-14 2024-02-14
US63/553,491 2024-02-14
US202463655212P 2024-06-03 2024-06-03
US63/655,212 2024-06-03

Publications (1)

Publication Number Publication Date
WO2025174896A1 true WO2025174896A1 (fr) 2025-08-21

Family

ID=96773467

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2025/015604 Pending WO2025174896A1 (fr) 2024-02-14 2025-02-12 Profondeur de champ étendue et haute définition obtenue par modification subsurfacique in vivo d'une lentille intraoculaire

Country Status (1)

Country Link
WO (1) WO2025174896A1 (fr)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150297343A1 (en) * 2012-01-24 2015-10-22 Frederic Hehn Improved intraocular lens and corresponding manufacturing method
WO2018060319A1 (fr) * 2016-09-30 2018-04-05 Sav-Iol Sa Procédé de fabrication d'une lentille ophtalmique intraoculaire et lentille ophtalmique obtenue par la mise en œuvre de ce procédé
US10456026B2 (en) * 2010-12-15 2019-10-29 Amo Wavefront Sciences, Llc Apparatus, system, and method for intraocular lens power calculation using a regression formula incorporating corneal spherical aberration
US10667682B2 (en) * 2015-04-17 2020-06-02 The Cleveland Clinic Foundation Assessment of low contrast visual sensitivity
US10898073B2 (en) * 2016-08-12 2021-01-26 Universidad De Murcia Optoelectronic binocular instrument for the correction of presbyopia and method for the binocular correction of presbyopia

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10456026B2 (en) * 2010-12-15 2019-10-29 Amo Wavefront Sciences, Llc Apparatus, system, and method for intraocular lens power calculation using a regression formula incorporating corneal spherical aberration
US20150297343A1 (en) * 2012-01-24 2015-10-22 Frederic Hehn Improved intraocular lens and corresponding manufacturing method
US10667682B2 (en) * 2015-04-17 2020-06-02 The Cleveland Clinic Foundation Assessment of low contrast visual sensitivity
US10898073B2 (en) * 2016-08-12 2021-01-26 Universidad De Murcia Optoelectronic binocular instrument for the correction of presbyopia and method for the binocular correction of presbyopia
WO2018060319A1 (fr) * 2016-09-30 2018-04-05 Sav-Iol Sa Procédé de fabrication d'une lentille ophtalmique intraoculaire et lentille ophtalmique obtenue par la mise en œuvre de ce procédé

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