WO2026041815A1 - Composition solide comprenant des particules porteuses - Google Patents

Composition solide comprenant des particules porteuses

Info

Publication number
WO2026041815A1
WO2026041815A1 PCT/EP2025/074178 EP2025074178W WO2026041815A1 WO 2026041815 A1 WO2026041815 A1 WO 2026041815A1 EP 2025074178 W EP2025074178 W EP 2025074178W WO 2026041815 A1 WO2026041815 A1 WO 2026041815A1
Authority
WO
WIPO (PCT)
Prior art keywords
carrier
calcium
template material
phosphate
particle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
PCT/EP2025/074178
Other languages
English (en)
Inventor
Maxim Puchkov
Roland Haag
Jonas KOST
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Galvita Ag
Original Assignee
Galvita Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galvita Ag filed Critical Galvita Ag
Publication of WO2026041815A1 publication Critical patent/WO2026041815A1/fr
Pending legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/501—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention concerne le domaine des particules porteuses. Plus particulièrement, l'invention concerne une particule porteuse structurée ayant une structure primaire et une structure interne secondaire, une matière de support compactée comprenant la particule de support, et une composition pharmaceutique solide comprenant la matière de support compactée de l'invention, ainsi que leurs procédés de production. De plus, l'invention concerne l'utilisation des particules de support, de la matière de support compactée ou de la composition pharmaceutique solide en thérapie, en diagnostic ou dans des produits alimentaires.
PCT/EP2025/074178 2024-08-23 2025-08-25 Composition solide comprenant des particules porteuses Pending WO2026041815A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP24196282.8 2024-08-23
EP24196282 2024-08-23

Publications (1)

Publication Number Publication Date
WO2026041815A1 true WO2026041815A1 (fr) 2026-02-26

Family

ID=92538614

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2025/074178 Pending WO2026041815A1 (fr) 2024-08-23 2025-08-25 Composition solide comprenant des particules porteuses

Country Status (1)

Country Link
WO (1) WO2026041815A1 (fr)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07196314A (ja) * 1993-12-28 1995-08-01 Maruo Calcium Co Ltd チューブ状合成無機微粒子
WO1999047253A1 (fr) 1998-03-19 1999-09-23 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Fabrication de particules et de coques creuses enduites multicouches par assemblage automatique de multicouches de nanocomposites sur des gabarits colloidaux decomposables
US6419954B1 (en) 2000-05-19 2002-07-16 Yamanouchi Pharmaceutical Co., Ltd. Tablets and methods for modified release of hydrophilic and other active agents
WO2022162023A1 (fr) 2021-01-28 2022-08-04 Galvita Ag Compositions pharmaceutiques solides et leurs procédés de production

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07196314A (ja) * 1993-12-28 1995-08-01 Maruo Calcium Co Ltd チューブ状合成無機微粒子
WO1999047253A1 (fr) 1998-03-19 1999-09-23 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Fabrication de particules et de coques creuses enduites multicouches par assemblage automatique de multicouches de nanocomposites sur des gabarits colloidaux decomposables
US6419954B1 (en) 2000-05-19 2002-07-16 Yamanouchi Pharmaceutical Co., Ltd. Tablets and methods for modified release of hydrophilic and other active agents
WO2022162023A1 (fr) 2021-01-28 2022-08-04 Galvita Ag Compositions pharmaceutiques solides et leurs procédés de production

Non-Patent Citations (27)

* Cited by examiner, † Cited by third party
Title
"CRC Handbook of Chemistry and Physics", 2014, NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY
"European Pharmacopeia", PHARMATRON AG, article "Resistance to Crushing of Tablets"
"IUPAC Compendium of Chemical Terminology", 2006, INTERNATIONAL UNION OF PURE AND APPLIED CHEMISTRY
AKASHKINA, L.V.EZERSKII, M.L., PHARM CHEM J, vol. 34, 2000, pages 324 - 326
BAUER, J. F., JOURNAL OF VALIDATION TECHNOLOGY, vol. 15, no. 1, 2009, pages 37 - 45
CARUSO, F ET AL., SCIENCE, vol. 282, no. 5391, 1998, pages 1111 - 1114
CHANDRAN, R.PANDA, S.K.MALLIK, A.: "A short review on the advancements in electroplating of CulnGaSe2 thin films", MATER RENEW SUSTAIN ENERGY, vol. 7, 2018, pages 6
COSKUN ELIF ET AL: "Synthesis strategies for core-shell and hollow-core hydroxyapatite particles and their applications", CERAMICS INTERNATIONAL, ELSEVIER, AMSTERDAM, NL, vol. 50, no. 20, 21 July 2024 (2024-07-21), pages 38851 - 38859, XP087601217, ISSN: 0272-8842, [retrieved on 20240721], DOI: 10.1016/J.CERAMINT.2024.07.301 *
DE SOUSA RODRIGUES, L. A. ET AL., COLLOIDS AND SURFACES B: BIOINTERFACES, vol. 103, 2013, pages 642 - 651
DECHER, G. H. J. D. ET AL., THIN SOLID FILMS, vol. 210, 1992, pages 831 - 835
GUO YA-JUN ET AL: "Hollow carbonated hydroxyapatite microspheres with mesoporous structure: Hydrothermal fabrication and drug delivery property", MATERIALS SCIENCE AND ENGINEERING C, ELSEVIER SCIENCE S.A, CH, vol. 33, no. 6, 1 April 2013 (2013-04-01), pages 3166 - 3172, XP028553329, ISSN: 0928-4931, DOI: 10.1016/J.MSEC.2013.03.040 *
KEMPKES, M.EGGERS, J.MAZZOTTI, M., CHEMICAL ENGINEERING SCIENCE, vol. 63, no. 19, 2008, pages 4656 - 4675
KITAZAWA, S. ET AL., THE JOURNAL OF PHARMACY AND PHARMACOLOGY, vol. 27, no. 10, 1975, pages 765 - 770
KOST ET AL., ADV. FUNCT. MATER., vol. 11, 2023
M. PELEG: "J. of Food Process Engineering", 1977, article "Flowability of food powders and methods for its evaluation - A review", pages: 303 - 328
MARKL, D. ET AL., INTERNATIONAL JOURNAL OF PHARMACEUTICS, vol. 538, no. 1-2, 2018, pages 188 - 214
ODEKU, O. A. ET AL., PHARMACEUTICAL REVIEWS, vol. 5, 2007, pages 2
PIETRZAK, K. ET AL., EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, vol. 96, 2015, pages 380 - 387
PITT ET AL.: "Tensile fracture of doubly-convex cylindrical discs under diametral loading", J. MATER. SCI., vol. 23, 1988, pages 2723 - 2728
ROSENHOLM, J. M. ET AL., NANOSCALE, vol. 2, no. 10, 2010, pages 1870 - 1883
SERIZAWA, T.KAMIMURA, S. ET AL., LANGMUIR, vol. 18, no. 22, 2002, pages 8381 - 8385
SHAFIQ FARISHTA ET AL: "Adsorption mechanism and synthesis of adjustable hollow hydroxyapatite spheres for efficient wastewater cationic dyes adsorption", COLLOIDS AND SURFACES A : PHYSIOCHEMICAL AND ENGINEERINGS ASPECTS, vol. 672, 1 September 2023 (2023-09-01), AMSTERDAM, NL, pages 131713, XP093240722, ISSN: 0927-7757, DOI: 10.1016/j.colsurfa.2023.131713 *
STANLEY ET AL.: "The tensile fracture stress of capsule-shaped tablets", J. PHARM. PHARMACOL., vol. 32, no. 12, 1980, pages 852 - 854
STIRNIMANN ET AL., PHARM. RES., vol. 30, 2013, pages 1915
SUCH, G. K. ET AL., CHEMICAL SOCIETY REVIEWS, vol. 40, no. 1, 2010, pages 19 - 29
WEI JING ET AL: "Hollow hydroxyapatite/polyelectrolyte hybrid microparticles with controllable size, wall thickness and drug delivery properties", JOURNAL OF MATERIALS CHEMISTRY. B, vol. 3, no. 41, 1 January 2015 (2015-01-01), GB, pages 8162 - 8169, XP093240714, ISSN: 2050-750X, DOI: 10.1039/C5TB01268F *
ZHANG, Y. ET AL., MACROMOLECULES, vol. 36, no. 11, 2003, pages 4238 - 4240

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