WO2026076344A1 - Méthode de traitement d'un patient ayant une insuffisance cardiaque et procédé de sélection d'un patient pour une procédure de splanchnicectomie - Google Patents

Méthode de traitement d'un patient ayant une insuffisance cardiaque et procédé de sélection d'un patient pour une procédure de splanchnicectomie

Info

Publication number
WO2026076344A1
WO2026076344A1 PCT/US2025/049409 US2025049409W WO2026076344A1 WO 2026076344 A1 WO2026076344 A1 WO 2026076344A1 US 2025049409 W US2025049409 W US 2025049409W WO 2026076344 A1 WO2026076344 A1 WO 2026076344A1
Authority
WO
WIPO (PCT)
Prior art keywords
patient
dpp
preload
computer executable
dhr
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
PCT/US2025/049409
Other languages
English (en)
Inventor
Pajhand Iranitalab
Horace Chesley HOSKINS
Matthew Allan STARK
Sami Isaac SOMO
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Axon Vascular Inc
Original Assignee
Axon Vascular Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Axon Vascular Inc filed Critical Axon Vascular Inc
Publication of WO2026076344A1 publication Critical patent/WO2026076344A1/fr
Pending legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00577—Ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/024—Measuring pulse rate or heart rate

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Otolaryngology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Vascular Medicine (AREA)
  • Physiology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)

Abstract

L'invention concerne des techniques de sélection et/ou de traitement de patients atteints d'insuffisance cardiaque, telle qu'une insuffisance cardiaque à fraction d'éjection préservée (ICFEP). Des tests de diagnostic sont utilisés pour déterminer si un patient est sensible à la précharge ou dépendant de la précharge sur la base de mesures telles que la pression d'impulsion delta (dPP) et la fréquence cardiaque delta (dHR). Les patients peuvent être sélectionnés en vue d'un traitement sur la base d'une telle détermination.
PCT/US2025/049409 2024-10-04 2025-10-03 Méthode de traitement d'un patient ayant une insuffisance cardiaque et procédé de sélection d'un patient pour une procédure de splanchnicectomie Pending WO2026076344A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202463703530P 2024-10-04 2024-10-04
US63/703,530 2024-10-04

Publications (1)

Publication Number Publication Date
WO2026076344A1 true WO2026076344A1 (fr) 2026-04-09

Family

ID=97677071

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2025/049409 Pending WO2026076344A1 (fr) 2024-10-04 2025-10-03 Méthode de traitement d'un patient ayant une insuffisance cardiaque et procédé de sélection d'un patient pour une procédure de splanchnicectomie

Country Status (1)

Country Link
WO (1) WO2026076344A1 (fr)

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018023132A1 (fr) 2016-07-29 2018-02-01 Axon Therepies, Inc. Dispositifs, systèmes et procédés pour le traitement de l'insuffisance cardiaque par ablation du nerf splanchnique
US20180110561A1 (en) * 2015-02-05 2018-04-26 Axon Therapies, Inc. Devices and methods for treatment of heart failure by splanchnic nerve ablation
US10207110B1 (en) 2015-10-13 2019-02-19 Axon Therapies, Inc. Devices and methods for treatment of heart failure via electrical modulation of a splanchnic nerve
US20190183569A1 (en) 2017-12-17 2019-06-20 Dorin Panescu Methods and devices for endovascular ablation of a splanchnic nerve
WO2020257763A1 (fr) 2019-06-20 2020-12-24 Axon Therapies, Inc. Méthodes et dispositifs pour l'ablation endovasculaire d'un nerf splanchnique
US20210220043A1 (en) 2020-01-17 2021-07-22 Pajhand Iranitalab Methods and devices for endovascular ablation of a splanchnic nerve
WO2022261022A1 (fr) 2021-06-07 2022-12-15 Axon Therapies, Inc. Procédés, dispositifs et systèmes pour traiter un patient par ablation de gsn
US11672595B1 (en) 2022-06-15 2023-06-13 Corveus Medical, Inc. Systems and methods for interrupting nerve activity to treat a medical condition

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180110561A1 (en) * 2015-02-05 2018-04-26 Axon Therapies, Inc. Devices and methods for treatment of heart failure by splanchnic nerve ablation
US10376308B2 (en) 2015-02-05 2019-08-13 Axon Therapies, Inc. Devices and methods for treatment of heart failure by splanchnic nerve ablation
US10207110B1 (en) 2015-10-13 2019-02-19 Axon Therapies, Inc. Devices and methods for treatment of heart failure via electrical modulation of a splanchnic nerve
US20190175912A1 (en) 2015-10-13 2019-06-13 Mark Gelfand Devices and methods for treatment of heart failure via electrical modulation of a splanchnic nerve
WO2018023132A1 (fr) 2016-07-29 2018-02-01 Axon Therepies, Inc. Dispositifs, systèmes et procédés pour le traitement de l'insuffisance cardiaque par ablation du nerf splanchnique
US20190183569A1 (en) 2017-12-17 2019-06-20 Dorin Panescu Methods and devices for endovascular ablation of a splanchnic nerve
WO2019118976A1 (fr) 2017-12-17 2019-06-20 Axon Therapies, Inc. Méthodes et dispositifs d'ablation endovasculaire d'un nerf splanchnique
WO2020257763A1 (fr) 2019-06-20 2020-12-24 Axon Therapies, Inc. Méthodes et dispositifs pour l'ablation endovasculaire d'un nerf splanchnique
US20210220043A1 (en) 2020-01-17 2021-07-22 Pajhand Iranitalab Methods and devices for endovascular ablation of a splanchnic nerve
WO2022261022A1 (fr) 2021-06-07 2022-12-15 Axon Therapies, Inc. Procédés, dispositifs et systèmes pour traiter un patient par ablation de gsn
US11672595B1 (en) 2022-06-15 2023-06-13 Corveus Medical, Inc. Systems and methods for interrupting nerve activity to treat a medical condition

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
AKSU TOLGA ET AL: "Cardioneuroablation for vasovagal syncope and atrioventricular block: A step-by-step guide", JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY., vol. 33, no. 10, 9 April 2022 (2022-04-09), US, pages 2205 - 2212, XP093348163, ISSN: 1045-3873, Retrieved from the Internet <URL:https://onlinelibrary.wiley.com/doi/full-xml/10.1111/jce.15480> DOI: 10.1111/jce.15480 *
FUDIM MARAT ET AL: "Endovascular Ablation of the Right Greater Splanchnic Nerve in Heart Failure With Preserved Ejection Fraction: Rationale, Design and Lead-in Phase Results of the REBALANCE-HF Trial", JOURNAL OF CARDIAL FAILURE., vol. 30, no. 7, 1 July 2024 (2024-07-01), US, pages 877 - 889, XP093347435, ISSN: 1071-9164, DOI: 10.1016/j.cardfail.2023.12.010 *

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