WO2026078058A1 - Composition nutritionnelle synthétique destinée à être utilisée dans la réduction du risque de diarrhée - Google Patents

Composition nutritionnelle synthétique destinée à être utilisée dans la réduction du risque de diarrhée

Info

Publication number
WO2026078058A1
WO2026078058A1 PCT/EP2025/078961 EP2025078961W WO2026078058A1 WO 2026078058 A1 WO2026078058 A1 WO 2026078058A1 EP 2025078961 W EP2025078961 W EP 2025078961W WO 2026078058 A1 WO2026078058 A1 WO 2026078058A1
Authority
WO
WIPO (PCT)
Prior art keywords
composition
phospholipid
diarrhoea
fraction
escherichia coli
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
PCT/EP2025/078961
Other languages
English (en)
Inventor
Roy Beernink
Teartse Tim Lambers
Outi Elina SIRKKA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
FrieslandCampina Nederland BV
Original Assignee
FrieslandCampina Nederland BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by FrieslandCampina Nederland BV filed Critical FrieslandCampina Nederland BV
Publication of WO2026078058A1 publication Critical patent/WO2026078058A1/fr
Pending legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/19—Dairy proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/688—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols both hydroxy compounds having nitrogen atoms, e.g. sphingomyelins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/20—Milk; Whey; Colostrum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/40—Transferrins, e.g. lactoferrins, ovotransferrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pediatric Medicine (AREA)
  • Dairy Products (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

L'invention concerne une composition nutritionnelle synthétique contenant une fraction de lait enrichie en phospholipides, 2'FL et LNnT destinée à être utilisée pour réduire le risque de diarrhée chez un sujet.
PCT/EP2025/078961 2024-10-09 2025-10-08 Composition nutritionnelle synthétique destinée à être utilisée dans la réduction du risque de diarrhée Pending WO2026078058A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP24205629.9 2024-10-09
EP24205629 2024-10-09

Publications (1)

Publication Number Publication Date
WO2026078058A1 true WO2026078058A1 (fr) 2026-04-16

Family

ID=93061674

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2025/078961 Pending WO2026078058A1 (fr) 2024-10-09 2025-10-08 Composition nutritionnelle synthétique destinée à être utilisée dans la réduction du risque de diarrhée

Country Status (1)

Country Link
WO (1) WO2026078058A1 (fr)

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110300229A1 (en) * 2007-08-09 2011-12-08 Fonterra Co-Operative Group Limited Treating or preventing rotavirus infection
WO2017194068A1 (fr) 2016-05-12 2017-11-16 Arla Foods Amba Préparation de lactosérum permettant d'améliorer le développement du cerveau
US20190160082A1 (en) * 2016-08-04 2019-05-30 Nestec S.A. Nutritional compositions with 2fl and lnnt for use in preventing and/or treating non-rotavirus diarrhea by acting on the gut microbiota dysbiosis
US20210227845A1 (en) * 2018-05-09 2021-07-29 Mead Johnson Nutrition Company Pediatric nutritional compositions and methods for infants delivered by c-section
WO2022112552A1 (fr) 2020-11-27 2022-06-02 Arla Foods Amba Nouvelle composition de lipides de lait enrichie en cholestérol appropriée pour la nutrition des nourrissons, procédé de production et compositions nutritionnelles comprenant la composition de lipides de lait
CN115669732B (zh) * 2022-12-29 2023-04-14 内蒙古伊利实业集团股份有限公司 含有母乳低聚糖LNnT的低致敏性婴儿部分水解配方食品
US20230173066A1 (en) * 2019-07-23 2023-06-08 Frieslandcampina Nederland B.V. Nutritional composition comprising milk fat and immunoglobulin
WO2024149806A1 (fr) 2023-01-11 2024-07-18 Frieslandcampina Nederland B.V. Utilisation d'une fraction de lait enrichie en phospholipides dans la prévention d'une infection par le vrs

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110300229A1 (en) * 2007-08-09 2011-12-08 Fonterra Co-Operative Group Limited Treating or preventing rotavirus infection
WO2017194068A1 (fr) 2016-05-12 2017-11-16 Arla Foods Amba Préparation de lactosérum permettant d'améliorer le développement du cerveau
US20190160082A1 (en) * 2016-08-04 2019-05-30 Nestec S.A. Nutritional compositions with 2fl and lnnt for use in preventing and/or treating non-rotavirus diarrhea by acting on the gut microbiota dysbiosis
US20210227845A1 (en) * 2018-05-09 2021-07-29 Mead Johnson Nutrition Company Pediatric nutritional compositions and methods for infants delivered by c-section
US20230173066A1 (en) * 2019-07-23 2023-06-08 Frieslandcampina Nederland B.V. Nutritional composition comprising milk fat and immunoglobulin
WO2022112552A1 (fr) 2020-11-27 2022-06-02 Arla Foods Amba Nouvelle composition de lipides de lait enrichie en cholestérol appropriée pour la nutrition des nourrissons, procédé de production et compositions nutritionnelles comprenant la composition de lipides de lait
CN115669732B (zh) * 2022-12-29 2023-04-14 内蒙古伊利实业集团股份有限公司 含有母乳低聚糖LNnT的低致敏性婴儿部分水解配方食品
WO2024149806A1 (fr) 2023-01-11 2024-07-18 Frieslandcampina Nederland B.V. Utilisation d'une fraction de lait enrichie en phospholipides dans la prévention d'une infection par le vrs

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
ANONYMOUS: "Publication on the health effects of 2'-FL", 1 June 2019 (2019-06-01), pages 1 - 4, XP093253459, Retrieved from the Internet <URL:https://www.frieslandcampinainstitute.com/uploads/sites/19/2024/03/FC-Institute-Publication-on-the-health-effects-of-2-FL.pdf> *
BRINK LAUREN R. ET AL: "In the Age of Viral Pandemic, Can Ingredients Inspired by Human Milk and Infant Nutrition Be Repurposed to Support the Immune System?", NUTRIENTS, vol. 13, no. 3, 6 March 2021 (2021-03-06), CH, pages 870, XP055922781, ISSN: 2072-6643, DOI: 10.3390/nu13030870 *
DATABASE GNPD [online] MINTEL; 2 August 2023 (2023-08-02), ANONYMOUS: "Stage 2 Follow-On Baby Formula", XP093253411, retrieved from https://www.gnpd.com/sinatra/recordpage/11008058/ Database accession no. 11008058 *
DATABASE GNPD [online] MINTEL; 24 January 2023 (2023-01-24), ANONYMOUS: "Stage 1 Baby Formula", XP093253414, retrieved from https://www.gnpd.com/sinatra/recordpage/10520098/ Database accession no. 10520098 *
FONTECHA JAVIER ET AL: "Sources, Production, and Clinical Treatments of Milk Fat Globule Membrane for Infant Nutrition and Well-Being", NUTRIENTS, vol. 12, no. 6, 30 May 2020 (2020-05-30), pages 1607, XP055947949, DOI: 10.3390/nu12061607 *
no. 13007-32-4
TEN BRUGGENCATE ET AL., J NUTR, vol. 146, 2016, pages 249 - 55

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