YU32178A - Process for obtaiing quinazoline compounds - Google Patents

Process for obtaiing quinazoline compounds

Info

Publication number: YU32178A
Authority: YU; Yugoslavia
Prior art keywords: obtaiing; quinazoline compounds; quinazoline; compounds; obtaiing quinazoline
Prior art date: 1977-02-22

Application number

YU00321/78A

Other languages

English (en)

Inventor

R R Grenshaw

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-02-22

Filing date

1978-02-13

Publication date

1983-01-21

1978-02-13 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1983-01-21 Publication of YU32178A publication Critical patent/YU32178A/xx

Links

125000002294 quinazolinyl group Chemical class N1=C(N=CC2=CC=CC=C12)* 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/06—1,2,3-Thiadiazoles; Hydrogenated 1,2,3-thiadiazoles

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

YU00321/78A 1977-02-22 1978-02-13 Process for obtaiing quinazoline compounds YU32178A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US05/770,966 US4101548A (en)	1977-02-22	1977-02-22	1,2,3-Thiadiazole amides

Publications (1)

Publication Number	Publication Date
YU32178A true YU32178A (en)	1983-01-21

Family

ID=25090261

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
YU00321/78A YU32178A (en)	1977-02-22	1978-02-13	Process for obtaiing quinazoline compounds
YU01982/82A YU198282A (en)	1977-02-22	1982-09-02	Process for obtaining quinazoline compounds
YU01983/82A YU198382A (en)	1977-02-22	1982-09-02	Process for obtaining quinazoline compounds
YU01984/82A YU198482A (en)	1977-02-22	1982-09-02	Process for obtaining quinazoline compounds

Family Applications After (3)

Application Number	Title	Priority Date	Filing Date
YU01982/82A YU198282A (en)	1977-02-22	1982-09-02	Process for obtaining quinazoline compounds
YU01983/82A YU198382A (en)	1977-02-22	1982-09-02	Process for obtaining quinazoline compounds
YU01984/82A YU198482A (en)	1977-02-22	1982-09-02	Process for obtaining quinazoline compounds

Country Status (19)

Country	Link
US (1)	US4101548A (da)
JP (1)	JPS53103485A (da)
AU (1)	AU518108B2 (da)
BE (1)	BE864095A (da)
CA (1)	CA1121820A (da)
CH (1)	CH634318A5 (da)
DE (1)	DE2807392A1 (da)
DK (1)	DK75178A (da)
FI (1)	FI780566A7 (da)
FR (1)	FR2381046A1 (da)
GB (1)	GB1586556A (da)
GR (1)	GR67024B (da)
IE (1)	IE46652B1 (da)
IT (1)	IT1105287B (da)
LU (1)	LU79087A1 (da)
NL (1)	NL7801996A (da)
SE (1)	SE7802022L (da)
YU (4)	YU32178A (da)
ZA (1)	ZA78992B (da)

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DE2728523C2 (de) *	1977-06-23	1986-02-27	Schering AG, 1000 Berlin und 4709 Bergkamen	4-Methyl-1,2,3-thiadiazol-5-carbonsäure-(cyclohexylmethyl)-amid, Mittel mit herbizider und wachstumsregulatorischer Wirkung enthaltend diese Verbindung sowie Verfahren zu seiner Herstellung
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US4351940A (en) *	1980-03-03	1982-09-28	Pfizer Inc.	Chloro- and alkoxy-substituted-2-chloro-4-aminodquinazolines
JPS5791987A (en) *	1980-11-26	1982-06-08	Sankyo Co Ltd	Aminoquinazoline derivative and its preparation
FI70411C (fi) *	1980-12-29	1986-09-19	Pfizer	Foerfarande foer framstaellning av nya antihypertensiva 4-amino-6,7-dimetoxi-2-piperazinokinazolin derivat
US4367335A (en) *	1981-08-03	1983-01-04	Mead Johnson & Company	Thiazolidinylalkylene piperazine derivatives
GB8320958D0 (en) *	1983-08-03	1983-09-07	Pfizer Ltd	Quinazoline cardiac stimulants
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US6232312B1 (en)	1995-06-07	2001-05-15	Cell Pathways, Inc.	Method for treating patient having precancerous lesions with a combination of pyrimidopyrimidine derivatives and esters and amides of substituted indenyl acetic acides
US6046206A (en) *	1995-06-07	2000-04-04	Cell Pathways, Inc.	Method of treating a patient having a precancerous lesions with amide quinazoline derivatives
US6060477A (en) *	1995-06-07	2000-05-09	Cell Pathways, Inc.	Method of treating a patient having precancerous lesions with phenyl cycloamino pyrimidinone derivatives
US6262059B1 (en)	1995-06-07	2001-07-17	Cell Pathways, Inc.	Method of treating a patient having precancerous lesions with quinazoline derivatives
US6200980B1 (en)	1995-06-07	2001-03-13	Cell Pathways, Inc.	Method of treating a patient having precancerous lesions with phenyl purinone derivatives
US5874440A (en) *	1995-06-07	1999-02-23	Cell Pathways, Inc.	Method of treating a patient having precancerous lesions with phenyl pyrimidinone derivatives
US6046216A (en) *	1995-06-07	2000-04-04	Cell Pathways, Inc.	Method of treating a patient having precancerous lesions with phenyl pyridinone derivatives
WO1997011698A1 (en) *	1995-09-29	1997-04-03	Merck & Co., Inc.	ALPHA 1b ADRENERGIC RECEPTOR ANTAGONISTS
US5858694A (en) *	1997-05-30	1999-01-12	Cell Pathways, Inc.	Method for identifying compounds for inhibition of cancerous lesions
CA2238283C (en) *	1997-05-30	2002-08-20	Cell Pathways, Inc.	Method for identifying compounds for inhibition of neoplastic lesions, pharmaceutical compositions from such compounds and uses of such compounds and compositions for treating neoplastic lesions
US5852035A (en) *	1997-12-12	1998-12-22	Cell Pathways, Inc.	Method for inhibiting neoplastic cells and related conditions by exposure to substituted N- arylmethyl and heterocyclmethyl-1H-pyrazolo (3,4-B) quinolin-4-amines
US6046199A (en) *	1998-01-14	2000-04-04	Cell Pathways, Inc.	Method of inhibiting neoplastic cells with tetracyclic pyrido[3,4-B]indole derivatives
US6410584B1 (en) *	1998-01-14	2002-06-25	Cell Pathways, Inc.	Method for inhibiting neoplastic cells with indole derivatives
US5942520A (en) *	1998-01-27	1999-08-24	Cell Pathways, Inc.	Method for inhibiting neoplastic cells by exposure to substituted N-cycloalkylmethyl-1-H-pyrazolo (3,4-B) quinolone-4 amines
US5990117A (en) *	1998-04-15	1999-11-23	Cell Pathways, Inc.	Method for inhibiting neoplastic cells and related conditions by exposure to quinazoline derivatives
US6180629B1 (en)	1998-08-14	2001-01-30	Cell Pathways, Inc.	[4,5]-Fused-1,3-disubstituted-1,2-diazine-6-one derivatives with nitrogen containing substitutents in position one for the treatment of neoplasia
US6124303A (en) *	1998-09-11	2000-09-26	Cell Pathways, Inc.	Method for inhibiting neoplastic cells and related conditions by exposure to 9-substituted 2-(2-N-aloxyphenyl) purin-6-ones
US6268372B1 (en)	1998-09-11	2001-07-31	Cell Pathways, Inc.	Method for inhibiting neoplastic cells and related conditions by exposure to 2,9-disubstituted purin-6-ones
US6130053A (en) *	1999-08-03	2000-10-10	Cell Pathways, Inc.	Method for selecting compounds for inhibition of neoplastic lesions
US6200771B1 (en)	1998-10-15	2001-03-13	Cell Pathways, Inc.	Method of using a novel phosphodiesterase in pharmaceutical screeing to identify compounds for treatment of neoplasia
US6133271A (en) *	1998-11-19	2000-10-17	Cell Pathways, Inc.	Method for inhibiting neoplastic cells and related conditions by exposure thienopyrimidine derivatives
US6187779B1 (en)	1998-11-20	2001-02-13	Cell Pathways, Inc.	Method for inhibiting neoplastic cells and related conditions by exposure to 2,8-disubstituted quinazoline derivatives
US6369092B1 (en)	1998-11-23	2002-04-09	Cell Pathways, Inc.	Method for treating neoplasia by exposure to substituted benzimidazole derivatives
US6034099A (en) *	1998-11-24	2000-03-07	Cell Pathways, Inc.	Method for inhibiting neoplastic lesions by administering 4-(arylmethylene)- 2, 3- dihydro-pyrazol-3-ones
US6486155B1 (en)	1998-11-24	2002-11-26	Cell Pathways Inc	Method of inhibiting neoplastic cells with isoquinoline derivatives
US6077842A (en) *	1998-11-24	2000-06-20	Cell Pathways, Inc.	Method of inhibiting neoplastic cells with pyrazolopyridylpyridazinone derivatives
US6025394A (en)	1999-01-29	2000-02-15	Cell Pathways, Inc.	Method for treating patients with acne by administering substituted sulfonyl indenyl acetic acids, amides and alcohols
US6020379A (en) *	1999-02-19	2000-02-01	Cell Pathways, Inc.	Position 7 substituted indenyl-3-acetic acid derivatives and amides thereof for the treatment of neoplasia
US6555547B1 (en)	2000-02-28	2003-04-29	Cell Pathways, Inc.	Method for treating a patient with neoplasia by treatment with a vinca alkaloid derivative
US6569638B1 (en)	2000-03-03	2003-05-27	Cell Pathways, Inc	Method for screening compounds for the treatment of neoplasia
US6420400B1 (en)	2000-04-07	2002-07-16	Kinetek Pharmaceuticals, Inc.	Antiproliferative 1,2,3-thiadiazole compounds
US7022702B2 (en)	2000-04-07	2006-04-04	Qlt Inc.	Antiproliferative 1,2,3-thiadiazole compounds
US6962940B2 (en)	2002-03-20	2005-11-08	Celgene Corporation	(+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione: methods of using and compositions thereof
US7276529B2 (en) *	2002-03-20	2007-10-02	Celgene Corporation	Methods of the treatment or prevention of exercise-induced asthma using (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione
US7893101B2 (en)	2002-03-20	2011-02-22	Celgene Corporation	Solid forms comprising (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions thereof, and uses thereof
US7208516B2 (en) *	2002-03-20	2007-04-24	Celgene Corporation	Methods of the treatment of psoriatic arthritis using (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione
CA2481385A1 (en) *	2002-04-12	2003-10-23	Celgene Corporation	Modulation of stem and progenitor cell differentiation, assays, and uses thereof
CN1658848A (zh) *	2002-04-12	2005-08-24	细胞基因公司	血管生成调节剂的鉴定方法,由此发现的化合物和使用该化合物的治疗方法
US20070155791A1 (en) *	2005-12-29	2007-07-05	Zeldis Jerome B	Methods for treating cutaneous lupus using aminoisoindoline compounds
WO2009120296A1 (en) *	2008-03-24	2009-10-01	Celgene Corporation	Treatment of psoriasis or psoriatic arthritis using cyclopropyl-n-{2-{(1s)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-3-oxoisoindoline-4-yl}carboxamide
WO2015200177A1 (en)	2014-06-23	2015-12-30	Celgene Corporation	Apremilast for the treatment of a liver disease or a liver function abnormality

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE942029C (de) *	1951-06-22	1956-04-26	American Cyanamid Co	Verfahren zur Herstellung von neuen, in 1-Stellung substituierten 4-Aminopiperazinderivaten
US3812127A (en) *	1966-10-31	1974-05-21	Pfizer	4-(quinolin-4-yl)piperazine-1-carboxylic acid esters
US3517005A (en) *	1967-10-26	1970-06-23	Pfizer & Co C	Certain 2- and 4-substituted quinazolines
US3511836A (en) *	1967-12-13	1970-05-12	Pfizer & Co C	2,4,6,7-tetra substituted quinazolines
US3635979A (en) *	1969-09-29	1972-01-18	Pfizer	Certain 6- and/or 7-alkoxy-substituted-2 4-bis(disubstituted amino) quinazolines
US3594980A (en) *	1969-10-03	1971-07-27	Charles C Diehl	Treating polluted gases in baffle chamber
US3669968A (en) *	1970-05-21	1972-06-13	Pfizer	Trialkoxy quinazolines
US3780040A (en) *	1972-06-02	1973-12-18	R Schnettler	2-substituted-3,4-dihydroquinazolines
JPS4966691A (da) *	1972-10-30	1974-06-27
US4001238A (en) *	1976-02-18	1977-01-04	Bristol-Myers Company	1,3,4-oxadiazole amides
US4001237A (en) *	1976-02-18	1977-01-04	Bristol-Myers Company	Oxazole, isoxazole, thiazole and isothiazole amides
US4138561A (en) *	1977-09-30	1979-02-06	Bristol-Myers Company	Cyanocarboxamidines and quinazoline process

1977
- 1977-02-22 US US05/770,966 patent/US4101548A/en not_active Expired - Lifetime
1978
- 1978-02-06 CA CA000296307A patent/CA1121820A/en not_active Expired
- 1978-02-08 GR GR55385A patent/GR67024B/el unknown
- 1978-02-13 YU YU00321/78A patent/YU32178A/xx unknown
- 1978-02-13 AU AU33224/78A patent/AU518108B2/en not_active Expired
- 1978-02-17 BE BE185288A patent/BE864095A/xx not_active IP Right Cessation
- 1978-02-17 JP JP1669078A patent/JPS53103485A/ja active Pending
- 1978-02-20 ZA ZA00780992A patent/ZA78992B/xx unknown
- 1978-02-20 LU LU79087A patent/LU79087A1/xx unknown
- 1978-02-20 DK DK75178A patent/DK75178A/da not_active Application Discontinuation
- 1978-02-21 DE DE19782807392 patent/DE2807392A1/de not_active Withdrawn
- 1978-02-21 FR FR7804955A patent/FR2381046A1/fr active Granted
- 1978-02-21 FI FI780566A patent/FI780566A7/fi not_active Application Discontinuation
- 1978-02-21 SE SE7802022A patent/SE7802022L/xx unknown
- 1978-02-21 GB GB6846/78A patent/GB1586556A/en not_active Expired
- 1978-02-21 IE IE369/78A patent/IE46652B1/en unknown
- 1978-02-21 IT IT48131/78A patent/IT1105287B/it active
- 1978-02-22 NL NL7801996A patent/NL7801996A/xx not_active Application Discontinuation
- 1978-02-22 CH CH193778A patent/CH634318A5/fr not_active IP Right Cessation
1982
- 1982-09-02 YU YU01982/82A patent/YU198282A/xx unknown
- 1982-09-02 YU YU01983/82A patent/YU198382A/xx unknown
- 1982-09-02 YU YU01984/82A patent/YU198482A/xx unknown

Also Published As

Publication number	Publication date
US4101548A (en)	1978-07-18
IT1105287B (it)	1985-10-28
SE7802022L (sv)	1978-08-23
FI780566A7 (fi)	1978-08-23
DE2807392A1 (de)	1978-08-24
IE46652B1 (en)	1983-08-10
DK75178A (da)	1978-08-23
AU518108B2 (en)	1981-09-17
FR2381046A1 (fr)	1978-09-15
YU198482A (en)	1983-01-21
YU198282A (en)	1983-01-21
JPS53103485A (en)	1978-09-08
GR67024B (da)	1981-05-20
NL7801996A (nl)	1978-08-24
YU198382A (en)	1983-01-21
FR2381046B1 (da)	1982-11-12
IE780369L (en)	1978-08-22
AU3322478A (en)	1979-08-23
CH634318A5 (fr)	1983-01-31
LU79087A1 (fr)	1978-09-28
IT7848131A0 (it)	1978-02-21
CA1121820A (en)	1982-04-13
BE864095A (fr)	1978-08-17
ZA78992B (en)	1979-09-26
GB1586556A (en)	1981-03-18

Publication	Publication Date	Title
YU198282A (en)	1983-01-21	Process for obtaining quinazoline compounds
YU211582A (en)	1983-02-28	Process for obtaining cardiostimulating quinazolines
YU42073B (en)	1988-04-30	Process for obtaining 1-oxadethiaceptham compounds
YU213078A (en)	1983-01-21	Process for obtaining sulfonylamidine compounds
YU250378A (en)	1983-04-30	Process for obtaining n-cyano-and n-alkinyl-2-(substitutedphenoxy)-butyramids
YU91478A (en)	1983-01-21	Process for obtaining hexahydro-gamma-carboline compounds
YU143678A (en)	1983-02-28	Process for obtaining substituted cyclopropylmethoxyanilides
YU137578A (en)	1983-01-21	Process for obtaining mercaptoacyl-aminobenzoylglycine
PT67821A (en)	1978-04-01	Process for preparing quinazoline derivatives
YU39417B (en)	1984-12-31	Process for obtaining auranophine
GB2003475B (en)	1982-03-17	Process for 2-chlorosulphinylazetidin-4-ones
YU42089B (en)	1988-04-30	Process for obtaining substituted 2-cyclopropyl-chromones
YU71178A (en)	1983-01-21	Process for obtaining 2-hydroxybenzothiazole compounds
YU42072B (en)	1988-04-30	Process for obtaining 1-oxadethiacepham compounds
YU160978A (en)	1982-08-31	Process for obtaining tetrahydro-s-triazine-thione
YU40674B (en)	1986-04-30	Process for obtaining di-n-propylacetonitrile
JPS53130670A (en)	1978-11-14	Substituted pireridivulpropanol derivtive related compounds and process for preparing same
YU65979A (en)	1983-01-21	Process for obtaining quinazoline
YU233278A (en)	1983-01-21	Process for obtaining quinazoline
YU42477B (en)	1988-10-31	Process for obtaining haloarylmalone amido-1-dethio-1-oxa-cephalosporins
YU54983A (en)	1984-02-29	Process for obtaining 1-oxadethiacepham compounds
JPS53116362A (en)	1978-10-11	Process for 16alphaamethylsteroid
IL54182A0 (en)	1978-06-15	Process for 3-beta-aminoazetiden-2-ones
YU7278A (en)	1983-01-21	Process for obtaining 1-formyl-dime-ring-indole-dihydroindole
YU297678A (en)	1982-10-31	Process for obtaining new 2-aryl-1h-pyrimidine compounds