YU4393A - Supstituisani heksahidroazepinoni i tetrahidrobenzazepinoni - Google Patents

Supstituisani heksahidroazepinoni i tetrahidrobenzazepinoni

Info

Publication number
YU4393A
YU4393A YU4393A YU4393A YU4393A YU 4393 A YU4393 A YU 4393A YU 4393 A YU4393 A YU 4393A YU 4393 A YU4393 A YU 4393A YU 4393 A YU4393 A YU 4393A
Authority
YU
Yugoslavia
Prior art keywords
substituted
tetrahydrobenzazepinones
hexahidroazepinones
compounds
novel
Prior art date
Application number
YU4393A
Other languages
English (en)
Serbo-Croatian (sh)
Inventor
A.J. Lowe
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of YU4393A publication Critical patent/YU4393A/sr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Pronalazak se odnosi na nove supstituisane heksahidroazepinone i tetrahidrobenzazepinone formule, u kojoj R1, Z1, Z2, Y1 i Y2 su kao što je ispod definisano, i na nove intermedijare upotrebljene pri sintezi takvih jedinjenja. Takva jedinjenja su korisna pri tretiranju i sprečavanju gastrointestinalnih poremećaja, bola i poremećaja uznemirenosti.
YU4393A 1992-01-27 1993-01-26 Supstituisani heksahidroazepinoni i tetrahidrobenzazepinoni YU4393A (sr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82567792A 1992-01-27 1992-01-27

Publications (1)

Publication Number Publication Date
YU4393A true YU4393A (sr) 1996-01-09

Family

ID=25244657

Family Applications (1)

Application Number Title Priority Date Filing Date
YU4393A YU4393A (sr) 1992-01-27 1993-01-26 Supstituisani heksahidroazepinoni i tetrahidrobenzazepinoni

Country Status (19)

Country Link
EP (1) EP0625145A1 (sr)
JP (1) JPH07503465A (sr)
KR (1) KR950700257A (sr)
CN (1) CN1074903A (sr)
AU (1) AU3276193A (sr)
BR (1) BR9207071A (sr)
CA (1) CA2117367A1 (sr)
CZ (1) CZ391092A3 (sr)
FI (1) FI943513A0 (sr)
HU (1) HUT70496A (sr)
IL (1) IL104472A0 (sr)
MX (1) MX9300409A (sr)
NO (1) NO942775L (sr)
NZ (1) NZ245759A (sr)
RU (1) RU94038063A (sr)
TW (1) TW213901B (sr)
WO (1) WO1993015059A1 (sr)
YU (1) YU4393A (sr)
ZA (1) ZA93582B (sr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2097688A1 (es) * 1993-07-14 1997-04-01 Pfizer Hexahidroazepinonas y tetrahidrobenzazepinonas sustituidas.
AU6686694A (en) * 1993-07-26 1995-02-20 Pfizer Inc. Tetrahydro-1h-benzazepinones and hexahydroazepinones as selective cholecystokinin-b receptor antagonists
DK0730581T3 (da) * 1993-11-22 2001-11-26 Merck & Co Inc 3-acylaminobezazepiner
US5453424A (en) * 1993-11-22 1995-09-26 Merck & Co., Inc. Furanodiazepines
FI971378L (fi) * 1994-10-04 1997-04-03 Pfizer Menetelmiä ja välituotteita 3-aminobentso(b)-atsepinonien valmistusta varten
JPH10511928A (ja) 1994-10-14 1998-11-17 グラクソ、ウェルカム、ソシエタ、ペル、アツィオーニ 睡眠障害の治療のためのｃｃｋ−ｂレセプター拮抗薬の使用
DE10153348A1 (de) 2001-10-29 2003-05-08 Gruenenthal Gmbh Substituierte Benzo(b)azepin-2-on-Verbindungen
KR20080031281A (ko) * 2005-06-16 2008-04-08 노파르티스 아게 락탐을 함유하는 ｈｃｖ 억제제

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0166357A3 (en) * 1984-06-26 1988-10-26 Merck & Co. Inc. Benzofused lactams and pharmaceutical compositions containing them
US4767756A (en) * 1987-07-17 1988-08-30 E. R. Squibb & Sons, Inc. 3-substituted benzazepines
EP0322779A3 (en) * 1987-12-29 1991-05-08 Yoshitomi Pharmaceutical Industries, Ltd. Benzolactam compounds and pharmaceutical uses thereof
US5206234A (en) * 1990-10-22 1993-04-27 Merck & Co., Inc. Benzolactam analogs as antagonists of cck

Also Published As

Publication number Publication date
AU3276193A (en) 1993-09-01
TW213901B (sr) 1993-10-01
FI943513A7 (fi) 1994-07-26
NO942775L (no) 1994-09-20
JPH07503465A (ja) 1995-04-13
CA2117367A1 (en) 1993-08-05
EP0625145A1 (en) 1994-11-23
IL104472A0 (en) 1993-05-13
HUT70496A (en) 1995-10-30
FI943513L (fi) 1994-07-26
BR9207071A (pt) 1995-12-05
MX9300409A (es) 1993-07-01
WO1993015059A1 (en) 1993-08-05
HU9402195D0 (en) 1994-09-28
NO942775D0 (no) 1994-07-26
CN1074903A (zh) 1993-08-04
RU94038063A (ru) 1996-05-27
KR950700257A (ko) 1995-01-16
CZ391092A3 (en) 1994-01-19
NZ245759A (en) 1997-06-24
FI943513A0 (fi) 1994-07-26
ZA93582B (en) 1994-07-27

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