YU68589A - Heteroconyugates of antibodies for use in controlling limfocite activity - Google Patents

Heteroconyugates of antibodies for use in controlling limfocite activity

Info

Publication number: YU68589A
Authority: YU; Yugoslavia
Prior art keywords: heteroconjugates; lymphocytes; antibodies; heteroconjugate; resulting
Prior art date: 1988-04-04

Application number

YU00685/89A

Other languages

English (en)

Inventor

J A Ledbetter

Original Assignee

Oncogen

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-04-04

Filing date

1989-04-04

Publication date

1991-10-31

1989-04-04 Application filed by Oncogen filed Critical Oncogen

1991-10-31 Publication of YU68589A publication Critical patent/YU68589A/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2809—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2806—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2812—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2815—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD8
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/289—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD45
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Immunology (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Microbiology (AREA)
Mycology (AREA)
Virology (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Spinning Or Twisting Of Yarns (AREA)
Coating With Molten Metal (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

YU00685/89A 1988-04-04 1989-04-04 Heteroconyugates of antibodies for use in controlling limfocite activity YU68589A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US17682588A	1988-04-04	1988-04-04
US27193488A	1988-11-14	1988-11-14

Publications (1)

Publication Number	Publication Date
YU68589A true YU68589A (en)	1991-10-31

Family

ID=26872636

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
YU00685/89A YU68589A (en)	1988-04-04	1989-04-04	Heteroconyugates of antibodies for use in controlling limfocite activity

Country Status (20)

Country	Link
EP (1)	EP0336379B1 (pt)
JP (1)	JP2613106B2 (pt)
KR (1)	KR100205833B1 (pt)
CN (1)	CN1058296C (pt)
AT (1)	ATE133866T1 (pt)
AU (1)	AU629204B2 (pt)
DE (1)	DE68925593T2 (pt)
DK (1)	DK173382B1 (pt)
ES (1)	ES2083960T3 (pt)
FI (1)	FI105320B (pt)
GR (1)	GR3019224T3 (pt)
HU (1)	HU213576B (pt)
IE (1)	IE72187B1 (pt)
IL (1)	IL89823A (pt)
MY (1)	MY106592A (pt)
NO (1)	NO178699C (pt)
NZ (1)	NZ228560A (pt)
PT (1)	PT90195B (pt)
YU (1)	YU68589A (pt)
ZA (1)	ZA892448B (pt)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5846799A (en) *	1988-06-14	1998-12-08	La Region Wallone	Human myeloperoxidase and its therapeutic application
US5460961A (en) *	1988-06-14	1995-10-24	La Region Wallonne	Human myeloperoxidase and its therapeutic application
US5681566A (en) *	1988-10-24	1997-10-28	3I Research Exploitation Limited	Antibody conjugates with two or more covalently linked FC regions
US6685941B1 (en)	1988-11-23	2004-02-03	The Regents Of The University Of Michigan	Methods of treating autoimmune disease via CTLA-4Ig
WO1991003493A1 (en) *	1989-08-29	1991-03-21	The University Of Southampton	Bi-or trispecific (fab)3 or (fab)4 conjugates
US5378815A (en) *	1989-10-20	1995-01-03	National Research Council Canada	Process for indirect targeted immunocytolysis
US6406696B1 (en)	1989-10-27	2002-06-18	Tolerance Therapeutics, Inc.	Methods of stimulating the immune system with anti-CD3 antibodies
WO1991006319A1 (en) *	1989-10-27	1991-05-16	Arch Development Corporation	Methods and compositions for promoting immunopotentiation
US5273743A (en) *	1990-03-09	1993-12-28	Hybritech Incorporated	Trifunctional antibody-like compounds as a combined diagnostic and therapeutic agent
IL97459A0 (en) *	1990-03-09	1992-06-21	Hybritech Inc	Trifunctional antibody-like compounds as a combined diagnostic and therapeutic agent
JPH05268986A (ja) *	1990-03-19	1993-10-19	Bristol Myers Squibb Co	モノクローナル抗体及びリンパ球の活性法
GB9021679D0 (en) *	1990-10-05	1990-11-21	Gorman Scott David	Antibody preparation
US6106835A (en) *	1991-04-19	2000-08-22	Tanox, Inc.	Modified binding molecules specific for T or B lymphocytes and their use as in vivo immune modulators
US6129916A (en) *	1991-04-19	2000-10-10	Tanox, Inc.	Method of Increasing activation on proliferation of T cells using antibody-microbead conjugates
CA2065658A1 (en) *	1991-04-19	1992-10-20	Tse-Wen Chang	Conjugates of liposomes or microbeads and antibodies specific for t lymphocytes and their use in vivo immune modulators
US6197298B1 (en)	1991-04-19	2001-03-06	Tanox, Inc.	Modified binding molecules specific for T lymphocytes and their use as in vivo immune modulators in animals
US5872222A (en) *	1991-04-19	1999-02-16	Tanox Biosystems, Inc.	Conjugates of polymers and antibodies specific for T lymphocytes, and their use as adjuvants
IE922233A1 (en) *	1991-07-10	1993-01-13	Augusto C Ochoa	Short-term anti-cd3 stimulation of lymphocytes to increase¹their in vivo activity
GB9206422D0 (en)	1992-03-24	1992-05-06	Bolt Sarah L	Antibody preparation
ATE173543T1 (de) *	1992-04-10	1998-12-15	Thomas Totterman	Verfahren zum nachweis einer cmv-infektion
US5635602A (en) *	1993-08-13	1997-06-03	The Regents Of The University Of California	Design and synthesis of bispecific DNA-antibody conjugates
DE69528894T2 (de)	1994-05-02	2003-03-27	Bernd Groner	Bifunktionelles protein, herstellung und verwendung
DE4421391C1 (de) *	1994-06-18	1995-11-30	Gsf Forschungszentrum Umwelt	Verwendung von Antikörpern gegen T-Zellen zur verlängerten Immunsuppression
EP0945139A1 (en) *	1998-03-23	1999-09-29	Katholieke Universiteit Nijmegen	Methods and means for the treatment of immune related diseases such as Graft vs. Host disease
AU783250B2 (en) *	1999-06-17	2005-10-06	Dartmouth College	Autologous adoptive immunotherapy with primed antigen-specific T cells or B cells
US7541184B2 (en)	2000-02-24	2009-06-02	Invitrogen Corporation	Activation and expansion of cells
US7572631B2 (en)	2000-02-24	2009-08-11	Invitrogen Corporation	Activation and expansion of T cells
DE10034607A1 (de) *	2000-07-20	2002-02-07	Gundram Jung	Multispezifisches Reagenz zur selektiven Stimulierung von Zelloberflächenrezeptoren
CA2462883A1 (en) *	2001-10-12	2003-04-17	Schering Corporation	Use of bispecific antibodies to regulate immune responses
GB0305702D0 (en) *	2003-03-12	2003-04-16	Univ Birmingham	Bispecific antibodies
JP7489407B2 (ja)	2019-05-21	2024-05-23	ノバルティスアーゲー	Ｃｄ１９結合分子及びその使用
WO2021160267A1 (en) *	2020-02-13	2021-08-19	UCB Biopharma SRL	Bispecific antibodies against cd9 and cd7
EP4378529A1 (en) *	2022-12-03	2024-06-05	Universitätsklinikum Hamburg-Eppendorf	Antibody for use in a therapy involving effector cell engagement

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4381292A (en) *	1980-11-14	1983-04-26	The Board Of Trustees Of The Leland Stanford Jr. University	Anti-human T-lymphocyte monoclonal antibody
EP0153871A3 (en) *	1984-03-01	1987-07-01	Centocor, Inc.	Antibody enhancement of immunogenicity of antigen
DE3583278D1 (de) *	1984-04-23	1991-07-25	Boston Biomed Res Inst	Doppelspezifische antikoerper-determinanten.
GB8605316D0 (en) *	1986-03-04	1986-04-09	Royal Free Hosp School Med	Immunosuppression
EP0241907A3 (en) *	1986-04-14	1989-09-13	The General Hospital Corporation	Heterobifunctional antibodies and method of use
GB8626412D0 (en) *	1986-11-05	1986-12-03	Clark M R	Antibodies
DE3850542T2 (de) *	1987-09-23	1994-11-24	Bristol Myers Squibb Co	Antikörper-Heterokonjugate zur Töting von HIV-infizierten Zellen.

1989
- 1989-03-30 FI FI891528A patent/FI105320B/fi not_active IP Right Cessation
- 1989-03-31 NO NO891375A patent/NO178699C/no not_active IP Right Cessation
- 1989-03-31 NZ NZ228560A patent/NZ228560A/xx unknown
- 1989-03-31 HU HU891607A patent/HU213576B/hu unknown
- 1989-04-03 ZA ZA892448A patent/ZA892448B/xx unknown
- 1989-04-03 IE IE105489A patent/IE72187B1/en not_active IP Right Cessation
- 1989-04-03 CN CN89101965A patent/CN1058296C/zh not_active Expired - Lifetime
- 1989-04-03 DK DK198901594A patent/DK173382B1/da not_active IP Right Cessation
- 1989-04-03 IL IL8982389A patent/IL89823A/en not_active IP Right Cessation
- 1989-04-03 MY MYPI89000419A patent/MY106592A/en unknown
- 1989-04-04 EP EP89105907A patent/EP0336379B1/en not_active Expired - Lifetime
- 1989-04-04 KR KR1019890004473A patent/KR100205833B1/ko not_active Expired - Fee Related
- 1989-04-04 PT PT90195A patent/PT90195B/pt not_active IP Right Cessation
- 1989-04-04 AT AT89105907T patent/ATE133866T1/de not_active IP Right Cessation
- 1989-04-04 DE DE68925593T patent/DE68925593T2/de not_active Expired - Lifetime
- 1989-04-04 JP JP1084148A patent/JP2613106B2/ja not_active Expired - Fee Related
- 1989-04-04 ES ES89105907T patent/ES2083960T3/es not_active Expired - Lifetime
- 1989-04-04 AU AU32423/89A patent/AU629204B2/en not_active Expired
- 1989-04-04 YU YU00685/89A patent/YU68589A/xx unknown
1996
- 1996-03-06 GR GR960400631T patent/GR3019224T3/el unknown

Also Published As

Publication number	Publication date
FI105320B (fi)	2000-07-31
KR100205833B1 (ko)	1999-07-01
ZA892448B (en)	1989-12-27
PT90195B (pt)	1994-06-30
JPH01304356A (ja)	1989-12-07
DK159489A (da)	1989-10-05
CN1058296C (zh)	2000-11-08
EP0336379A2 (en)	1989-10-11
AU629204B2 (en)	1992-10-01
DK173382B1 (da)	2000-09-11
GR3019224T3 (en)	1996-06-30
EP0336379B1 (en)	1996-02-07
KR890015751A (ko)	1989-11-25
MY106592A (en)	1995-06-30
IL89823A (en)	1994-07-31
DE68925593D1 (de)	1996-03-21
ATE133866T1 (de)	1996-02-15
PT90195A (pt)	1989-11-10
FI891528A0 (fi)	1989-03-30
ES2083960T3 (es)	1996-05-01
FI891528L (fi)	1989-10-05
HUT51338A (en)	1990-04-28
DK159489D0 (da)	1989-04-03
CN1036988A (zh)	1989-11-08
EP0336379A3 (en)	1990-01-31
NO891375L (no)	1989-10-05
JP2613106B2 (ja)	1997-05-21
IE891054L (en)	1989-10-04
AU3242389A (en)	1989-10-05
NZ228560A (en)	1991-10-25
IE72187B1 (en)	1997-03-26
HU213576B (en)	1997-08-28
IL89823A0 (en)	1989-12-15
NO178699B (no)	1996-02-05
NO178699C (no)	1996-05-15
DE68925593T2 (de)	1996-06-13
NO891375D0 (no)	1989-03-31

Publication	Publication Date	Title
YU68589A (en)	1991-10-31	Heteroconyugates of antibodies for use in controlling limfocite activity
GR3020108T3 (en)	1996-08-31	Monoclonal antibody reactive with a novel HLA determinant on MHC class I molecules and method for activating lymphocytes
ES2106195T3 (es)	1997-11-01	Anticuerpo igg aglicosilado anti cd3.
DE3380697D1 (en)	1989-11-16	Monoclonal antibody
IL88248A (en)	1993-03-15	Solid phase immunoassay for detecting hiv antigens using kc-57 monoclonal antibody, and kit for the performance thereof
EP0597829A4 (en)	1992-02-27	MONOCLONAL ANTIBODIES AGAINST A NEW ANTIQUE ASSOCIATED WITH HUMAN TUMORS.
DE69021953D1 (de)	1995-10-05	Enzymimmuntest für Antigene und dafür verwendbare feste Phase.
EP0363109A3 (en)	1991-07-10	Determination of a chlamydial or gonococcal antigen using a positively-charged ionically binding support
EP0313986A3 (en)	1990-09-26	Immunoassays using antigens produced in heterologous organisms
DE3463975D1 (en)	1987-07-02	Diagnostic test system
GB2233091B (en)	1992-05-27	Immunoassays using monoclonal antibodies directed against natural binding proteins
ES546594A0 (es)	1987-04-01	Un procedimiento para preparar un anticuerpo monocional anti-urocinasa.
DK673789D0 (da)	1989-12-29	Monoklonalt antistof, som specifikt binder til kc-48-antigenet i neutrophiler og eosinophiler, samt hybridomocellelinie, som producerer antistoffet
ATE239754T1 (de)	2003-05-15	An nukleinsäure gebundenes polypeptid, verfahren zur herstellung eines an nukleinsäure gebundenen polypeptides und immunoassay, in dem dieses polypeptid verwendung findet
NO903788D0 (no)	1990-08-29	Monoklonalt antistoff mot protein c.
DE3990097T1 (de)	1990-11-22	Immunoassays unter verwendung monoklonaler antikoerper, die gegen natuerliche bindende proteine gerichtet sind
ZA89257B (en)	1989-10-25	Antigen antibody conjugate
IT8821547A0 (it)	1988-07-29	Metodo immunologico per la determinazione di anticorpi anti antigeni di microorganismi, mediante anticorpi antiidiotipo e mezzi adatti allo scopo.