ZA200000169B - Process for the preparation of pellets with a content of up to 90 wt.% of a pharmaceutical active ingredient. - Google Patents

Process for the preparation of pellets with a content of up to 90 wt.% of a pharmaceutical active ingredient.

Info

Publication number
ZA200000169B
ZA200000169B ZA200000169A ZA200000169A ZA200000169B ZA 200000169 B ZA200000169 B ZA 200000169B ZA 200000169 A ZA200000169 A ZA 200000169A ZA 200000169 A ZA200000169 A ZA 200000169A ZA 200000169 B ZA200000169 B ZA 200000169B
Authority
ZA
South Africa
Prior art keywords
pellets
preparation
content
active ingredient
pharmaceutical active
Prior art date
Application number
ZA200000169A
Other languages
English (en)
Inventor
Johannes Heinric Bartholomaeus
Iris Ziegler
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of ZA200000169B publication Critical patent/ZA200000169B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA200000169A 1999-01-18 2000-01-17 Process for the preparation of pellets with a content of up to 90 wt.% of a pharmaceutical active ingredient. ZA200000169B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19901692A DE19901692C2 (de) 1999-01-18 1999-01-18 Verfahren zur Herstellung von Pellets mit einem Gehalt von bis zu 90 Gew.% eines pharmazeutischen Wirkstoffes

Publications (1)

Publication Number Publication Date
ZA200000169B true ZA200000169B (en) 2000-08-07

Family

ID=7894569

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200000169A ZA200000169B (en) 1999-01-18 2000-01-17 Process for the preparation of pellets with a content of up to 90 wt.% of a pharmaceutical active ingredient.

Country Status (18)

Country Link
US (1) US6558704B1 (cs)
EP (1) EP1020181A1 (cs)
JP (1) JP2000212068A (cs)
KR (1) KR20000076475A (cs)
CN (1) CN1161108C (cs)
AU (1) AU764280C (cs)
CA (1) CA2295470A1 (cs)
CO (1) CO4910118A1 (cs)
CZ (1) CZ291936B6 (cs)
DE (1) DE19901692C2 (cs)
HU (1) HUP0000141A3 (cs)
IL (1) IL134079A (cs)
NZ (1) NZ502264A (cs)
PE (1) PE20001414A1 (cs)
PL (1) PL337864A1 (cs)
RU (1) RU2221553C2 (cs)
SK (1) SK285423B6 (cs)
ZA (1) ZA200000169B (cs)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9107804B2 (en) 2002-12-10 2015-08-18 Nortec Development Associates, Inc. Method of preparing biologically active formulations

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2226886T3 (es) * 1999-08-31 2005-04-01 Grunenthal Gmbh Forma de administracion de accion retardada que contiene sacarinato de tramadol.
FR2827771B1 (fr) * 2001-07-25 2003-10-24 Apis Spheromont Formulation et procede de preparation de spheroides pouvant etre fortement titres et a dispersion rapide
US20050182056A9 (en) * 2002-02-21 2005-08-18 Seth Pawan Modified release formulations of at least one form of tramadol
US8128957B1 (en) 2002-02-21 2012-03-06 Valeant International (Barbados) Srl Modified release compositions of at least one form of tramadol
US20060153908A1 (en) * 2002-06-27 2006-07-13 Brian Strong Spherical pellet formulations
TW200404004A (en) * 2002-09-09 2004-03-16 Ss Pharmaceutical Co Molded medicament for promotion of sleeping
KR100510270B1 (ko) * 2002-11-29 2005-08-26 센츄론(주) 펠렛타이저를 이용한 서방성 제제의 제조방법
US8802139B2 (en) 2003-06-26 2014-08-12 Intellipharmaceutics Corp. Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
US8394409B2 (en) * 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
US20060024361A1 (en) * 2004-07-28 2006-02-02 Isa Odidi Disintegrant assisted controlled release technology
US10624858B2 (en) * 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
EP1629834A1 (en) † 2004-08-27 2006-03-01 KRKA, D.D., Novo Mesto Sustained release pharmaceutical composition of tolterodine
NZ565108A (en) * 2005-07-07 2011-10-28 Farnam Co Inc Sustained release pharmaceutical compositions for highly water soluble drugs
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
US20070190141A1 (en) * 2006-02-16 2007-08-16 Aaron Dely Extended release opiate composition
CN101453996B (zh) * 2006-04-03 2016-05-11 伊萨·奥迪迪 药物递送组合物
JP5457830B2 (ja) 2006-04-03 2014-04-02 オディディ，イサ オルガノゾル被膜を含む制御放出送達デバイス
US10960077B2 (en) * 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
US7979151B2 (en) * 2007-12-06 2011-07-12 International Business Machines Corporation Run-time dispatch system for enhanced product characterization capability
TWI400089B (zh) * 2009-11-24 2013-07-01 Nippon Soda Co 羥烷基纖維素微粒子
DE102012007671A1 (de) 2012-04-16 2013-10-17 Acino Pharma Ag Pellets mit hohem Wirkstoffgehalt
US11065207B2 (en) 2016-03-25 2021-07-20 Universiteit Gent Oral dosage form
US10966928B2 (en) 2016-03-25 2021-04-06 Universiteit Gent Oral dosage form
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
WO2018087109A1 (de) 2016-11-08 2018-05-17 Grünenthal GmbH Multipartikuläre arzneiform mit kontrollierter freisetzung von metamizol

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2581541B1 (fr) * 1985-05-09 1988-05-20 Rhone Poulenc Sante Nouvelles compositions pharmaceutiques permettant la liberation prolongee d'un principe actif et leur procede de preparation
GB9119052D0 (en) * 1991-09-06 1991-10-23 Boots Co Plc Pharmaceutical compositions
US5234697A (en) * 1992-06-22 1993-08-10 Digestive Care Inc. Compositions of gastric acid-resistant microspheres containing salts of bile acids
RU2034533C1 (ru) * 1993-02-25 1995-05-10 Химико-фармацевтическое акционерное общество открытого типа "Октябрь" Анальгезирующее жаропонижающее лекарственное средство и способ его получения
DE4329794C2 (de) * 1993-09-03 1997-09-18 Gruenenthal Gmbh Tramadolsalz enthaltende Arzneimittel mit verzögerter Wirkstofffreisetzung
GB9422154D0 (en) 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
DE19710008A1 (de) * 1997-03-12 1998-09-17 Basf Ag Feste, mindestens zweiphasige Zubereitungsformen eines Opioid-Analgeticums mit verzögerter Freisetzung

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9107804B2 (en) 2002-12-10 2015-08-18 Nortec Development Associates, Inc. Method of preparing biologically active formulations
US10039717B2 (en) 2002-12-10 2018-08-07 Nortec Development Associates, Inc. Method of preparing biologically active formulations
US10646444B2 (en) 2002-12-10 2020-05-12 Nortec Development Associates, Inc. Method of preparing biologically formulations active

Also Published As

Publication number Publication date
CZ2000167A3 (cs) 2000-09-13
EP1020181A1 (de) 2000-07-19
IL134079A (en) 2004-12-15
JP2000212068A (ja) 2000-08-02
PL337864A1 (en) 2000-07-31
AU764280C (en) 2004-06-24
CO4910118A1 (es) 2000-04-24
AU1244200A (en) 2000-07-20
PE20001414A1 (es) 2000-12-23
SK682000A3 (en) 2000-08-14
HU0000141D0 (en) 2000-03-28
CN1270025A (zh) 2000-10-18
HUP0000141A2 (hu) 2000-12-28
IL134079A0 (en) 2001-04-30
KR20000076475A (ko) 2000-12-26
HUP0000141A3 (en) 2001-01-29
DE19901692A1 (de) 2000-07-20
SK285423B6 (sk) 2007-01-04
CN1161108C (zh) 2004-08-11
NZ502264A (en) 2001-11-30
RU2221553C2 (ru) 2004-01-20
DE19901692C2 (de) 2002-06-20
US6558704B1 (en) 2003-05-06
CZ291936B6 (cs) 2003-06-18
CA2295470A1 (en) 2000-07-18
AU764280B2 (en) 2003-08-14

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