ZA200100607B - Methods of treating diabetic cardiomyopathy using glycogen phosphorylase inhibitors. - Google Patents
Methods of treating diabetic cardiomyopathy using glycogen phosphorylase inhibitors.Info
- Publication number
- ZA200100607B ZA200100607B ZA200100607A ZA200100607A ZA200100607B ZA 200100607 B ZA200100607 B ZA 200100607B ZA 200100607 A ZA200100607 A ZA 200100607A ZA 200100607 A ZA200100607 A ZA 200100607A ZA 200100607 B ZA200100607 B ZA 200100607B
- Authority
- ZA
- South Africa
- Prior art keywords
- methods
- glycogen phosphorylase
- treating diabetic
- phosphorylase inhibitors
- diabetic cardiomyopathy
- Prior art date
Links
- 208000032781 Diabetic cardiomyopathy Diseases 0.000 title 1
- 102000007390 Glycogen Phosphorylase Human genes 0.000 title 1
- 108010046163 Glycogen Phosphorylase Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
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- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Pulmonology (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17777000P | 2000-01-24 | 2000-01-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200100607B true ZA200100607B (en) | 2002-07-22 |
Family
ID=22649922
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200100607A ZA200100607B (en) | 2000-01-24 | 2001-01-22 | Methods of treating diabetic cardiomyopathy using glycogen phosphorylase inhibitors. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6867184B2 (fr) |
| EP (1) | EP1125580A3 (fr) |
| JP (1) | JP2001206856A (fr) |
| KR (1) | KR20010083148A (fr) |
| AU (1) | AU1639901A (fr) |
| CA (1) | CA2331847A1 (fr) |
| CO (1) | CO5271699A1 (fr) |
| HU (1) | HUP0100321A3 (fr) |
| IL (1) | IL140904A0 (fr) |
| NZ (1) | NZ509481A (fr) |
| PE (1) | PE20011053A1 (fr) |
| ZA (1) | ZA200100607B (fr) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0021831D0 (en) * | 2000-09-06 | 2000-10-18 | Astrazeneca Ab | Chemical compounds |
| WO2002034285A2 (fr) * | 2000-10-20 | 2002-05-02 | Coolidge Thomas R | Traitement du myocarde hibernant et de la cardiomiopathie diabétique par un peptide glp-1 |
| EP1452526A1 (fr) * | 2001-10-29 | 2004-09-01 | Japan Tobacco Inc. | Compose indolique, et utilisation a des fins therapeutiques |
| GB0205175D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205176D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205162D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205165D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205166D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205170D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| AU2003227257A1 (en) * | 2002-03-27 | 2003-10-08 | Mitsubishi Pharma Corporation | Medicine for prevention and/or therapy of cardiomyopathy |
| US6960610B2 (en) * | 2002-10-28 | 2005-11-01 | Novo Nordick, A/S | Use of glycogen phosphorylase inhibitors for treatment of cardiovascular diseases |
| US20040209803A1 (en) * | 2002-12-19 | 2004-10-21 | Alain Baron | Compositions for the treatment and prevention of nephropathy |
| US7790681B2 (en) * | 2002-12-17 | 2010-09-07 | Amylin Pharmaceuticals, Inc. | Treatment of cardiac arrhythmias with GLP-1 receptor ligands |
| GB0309154D0 (en) * | 2003-01-14 | 2003-05-28 | Aventis Pharma Inc | Use of insulin glargine to reduce or prevent cardiovascular events in patients being treated for dysglycemia |
| JP2006519229A (ja) * | 2003-02-13 | 2006-08-24 | アルバート・アインシュタイン・カレッジ・オヴ・メディシン・オヴ・イェシヴァ・ユニヴァーシティ | 視床下部内の長鎖脂肪アシルCoAレベルの変調による摂食量およびグルコース産生量の調節 |
| WO2006041922A2 (fr) * | 2004-10-08 | 2006-04-20 | Dara Biosciences, Inc. | Agents, et procedes d'administration au systeme nerveux central |
| WO2006055463A2 (fr) * | 2004-11-15 | 2006-05-26 | Bristol-Myers Squibb Company | Derives de 2-amino-3-tetraline fonctionnalisee et inhibiteurs de la glycogene phosphorylase associes |
| WO2006055462A1 (fr) | 2004-11-15 | 2006-05-26 | Bristol-Myers Squibb Company | Derives 2-amino-4- tetraline fonctionnalisee et inhibiteurs de la glycogene phosphorylase associes |
| WO2006053274A2 (fr) * | 2004-11-15 | 2006-05-18 | Bristol-Myers Squibb Company | Derives de tetraline 2-amino-1-fonctionnalises et inhibiteurs correspondants de glycogene phosphorylase |
| US7223786B2 (en) * | 2004-11-15 | 2007-05-29 | Bristol-Myers Squibb Company | 2-aminonaphthalene derivatives and related glycogen phosphorylase inhibitors |
| US20070026079A1 (en) * | 2005-02-14 | 2007-02-01 | Louis Herlands | Intranasal administration of modulators of hypothalamic ATP-sensitive potassium channels |
| PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
| CN101516834B (zh) * | 2006-09-13 | 2013-04-03 | 塞诺菲-安万特股份有限公司 | 用作凝血因子IXa抑制剂的异丝氨酸衍生物 |
| KR101481041B1 (ko) * | 2007-11-30 | 2015-01-12 | (주)아모레퍼시픽 | 글루코오스-6-인산 탈수소효소의 활성 억제제 및 이를포함하는 지방세포 분화 억제용 조성물 |
| CA2880432C (fr) | 2012-08-21 | 2023-03-14 | Ardelyx, Inc. | Composes et procedes destines a inhiber un antiport medie par nhe dans le traitement des troubles associes a une retention de fluide ou a une surcharge de sel et des troubles du t ractus gastro-intestinal |
| KR102687458B1 (ko) * | 2016-06-16 | 2024-07-24 | 호유 가부시키가이샤 | 생선 알레르기의 항원 |
| HUE058867T2 (hu) | 2017-12-15 | 2022-09-28 | Medizinische Hochschule Hannover | Javított vegyület szívelégtelenség kezelésére |
| CN113304149A (zh) * | 2021-06-23 | 2021-08-27 | 广州医科大学 | 一种化合物在制备治疗2型糖尿病心肌病的药物中的应用 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3629545A1 (de) | 1986-08-30 | 1988-03-10 | Bayer Ag | Dihydropyridinverbindungen, verfahren zu ihrer herstellung und ihre verwendung |
| AU1890295A (en) | 1994-03-09 | 1995-09-25 | Novo Nordisk A/S | Piperidines and pyrrolidines |
| FI974437A0 (fi) | 1995-06-06 | 1997-12-05 | Pfizer | Substituoituja N-(indoli-2-karbonyyli)amideja ja johdannaisia glykogeenifosforylaasi-inhibiittoreina |
| JP3314938B2 (ja) | 1995-06-06 | 2002-08-19 | ファイザー・インコーポレーテッド | グリコーゲンホスホリラーゼ抑制剤としての置換されたn−(インドール−2−カルボニル)−グリシンアミド類および誘導体 |
| EP1040827A3 (fr) | 1995-09-08 | 2000-10-11 | Novo Nordisk A/S | Utilisation de 3,4-dihydroxy-2-hydroxyméthylepyrrolidine pour le traitement du diabète |
| AU2090897A (en) | 1996-02-29 | 1997-09-16 | Mikael Bols | Hydroxyhexahydropyridazines |
| US5952322A (en) | 1996-12-05 | 1999-09-14 | Pfizer Inc. | Method of reducing tissue damage associated with non-cardiac ischemia using glycogen phosphorylase inhibitors |
| ZA981920B (en) | 1997-03-07 | 1998-09-07 | Novo Nordisk As | Novel heterocyclic compounds |
| IL124236A (en) | 1997-05-05 | 2003-01-12 | Pfizer | Pharmaceutical composition for treating or reversing diabetic cardiomyopathy comprising aldose reductase inhibitor |
| WO1998050359A1 (fr) | 1997-05-06 | 1998-11-12 | Novo Nordisk A/S | Nouveaux composes heterocycliques |
| UA57811C2 (uk) | 1997-11-21 | 2003-07-15 | Пфайзер Продактс Інк. | Фармацевтична композиція, що містить інгібітор альдозоредуктази та інгібітор глікогенфосфорилази (варіанти), комплект, який її включає, та способи лікування ссавців зі станом інсулінорезистентності |
| US5998463A (en) | 1998-02-27 | 1999-12-07 | Pfizer Inc | Glycogen phosphorylase inhibitors |
| EP0978279A1 (fr) | 1998-08-07 | 2000-02-09 | Pfizer Products Inc. | Inhibiteurs de la glycogene phosphorylase |
| ES2215570T3 (es) * | 1999-04-01 | 2004-10-16 | Pfizer Products Inc. | Compuestos para tratar y prevenir complicaciones diabeticas. |
| DE60007592T2 (de) | 1999-09-30 | 2004-09-16 | Pfizer Products Inc., Groton | Bicyclische Pyrrolylamide als Glycogenphosphorylase-Inhibitoren |
| PE20011184A1 (es) * | 2000-03-16 | 2001-11-15 | Pfizer Prod Inc | Composiciones farmaceuticas de inhibidores de la glucogeno-fosforilasa |
| UY26615A1 (es) | 2000-03-16 | 2001-10-25 | Pfizer Prod Inc | Inhibidor de la glucogeno fosforilasa. |
| US6277877B1 (en) * | 2000-08-15 | 2001-08-21 | Pfizer, Inc. | Substituted n-(indole-2-carbonyl)glycinamides and derivates as glycogen phosphorylase inhibitors |
| GB0021831D0 (en) | 2000-09-06 | 2000-10-18 | Astrazeneca Ab | Chemical compounds |
| US9006243B2 (en) | 2006-12-29 | 2015-04-14 | Janssen R&D Ireland | HIV inhibiting 6-substituted pyrimidines |
-
2000
- 2000-12-27 CO CO00097924A patent/CO5271699A1/es not_active Application Discontinuation
-
2001
- 2001-01-15 IL IL14090401A patent/IL140904A0/xx unknown
- 2001-01-19 NZ NZ509481A patent/NZ509481A/en unknown
- 2001-01-22 ZA ZA200100607A patent/ZA200100607B/xx unknown
- 2001-01-22 CA CA002331847A patent/CA2331847A1/fr not_active Abandoned
- 2001-01-23 HU HU0100321A patent/HUP0100321A3/hu unknown
- 2001-01-23 EP EP01300575A patent/EP1125580A3/fr not_active Withdrawn
- 2001-01-23 PE PE2001000073A patent/PE20011053A1/es not_active Application Discontinuation
- 2001-01-23 US US09/767,633 patent/US6867184B2/en not_active Expired - Fee Related
- 2001-01-23 JP JP2001014036A patent/JP2001206856A/ja active Pending
- 2001-01-23 AU AU16399/01A patent/AU1639901A/en not_active Abandoned
- 2001-01-26 KR KR1020010003820A patent/KR20010083148A/ko not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| IL140904A0 (en) | 2002-02-10 |
| JP2001206856A (ja) | 2001-07-31 |
| US6867184B2 (en) | 2005-03-15 |
| HU0100321D0 (en) | 2001-03-28 |
| EP1125580A3 (fr) | 2002-11-27 |
| NZ509481A (en) | 2005-02-25 |
| PE20011053A1 (es) | 2001-10-17 |
| CA2331847A1 (fr) | 2001-07-24 |
| HUP0100321A3 (en) | 2004-03-01 |
| US20010046958A1 (en) | 2001-11-29 |
| KR20010083148A (ko) | 2001-08-31 |
| EP1125580A2 (fr) | 2001-08-22 |
| HUP0100321A2 (en) | 2002-10-28 |
| AU1639901A (en) | 2001-07-26 |
| CO5271699A1 (es) | 2003-04-30 |
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