ZA200103755B - Use of paclitaxel stabilized with albumin for preparing a drug for the treatment of solid tumors and the drug obtained thereby. - Google Patents

Use of paclitaxel stabilized with albumin for preparing a drug for the treatment of solid tumors and the drug obtained thereby.

Info

Publication number: ZA200103755B
Authority: ZA; South Africa
Prior art keywords: drug; albumin; preparing; treatment; solid tumors
Prior art date: 2000-05-18

Application number

ZA200103755A

Other languages

English (en)

Inventor

Marco Falciani

Original Assignee

Acs Dobfar Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-05-18

Filing date

2001-05-09

Publication date

2001-11-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11445079&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200103755(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2001-05-09 Application filed by Acs Dobfar Spa filed Critical Acs Dobfar Spa

2001-11-15 Publication of ZA200103755B publication Critical patent/ZA200103755B/xx

Links

229940079593 drug Drugs 0.000 title abstract 4
239000003814 drug Substances 0.000 title abstract 4
229930012538 Paclitaxel Natural products 0.000 title abstract 3
229960001592 paclitaxel Drugs 0.000 title abstract 3
RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 title abstract 3
102000009027 Albumins Human genes 0.000 title abstract 2
108010088751 Albumins Proteins 0.000 title abstract 2
206010028980 Neoplasm Diseases 0.000 title abstract 2
239000011859 microparticle Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5169—Proteins, e.g. albumin, gelatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5052—Proteins, e.g. albumin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Nanotechnology (AREA)
Optics & Photonics (AREA)
Biomedical Technology (AREA)
Physics & Mathematics (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Dispersion Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Inorganic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

ZA200103755A 2000-05-18 2001-05-09 Use of paclitaxel stabilized with albumin for preparing a drug for the treatment of solid tumors and the drug obtained thereby. ZA200103755B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT2000MI001107A ITMI20001107A1 (it)	2000-05-18	2000-05-18	Metodo per il trattamento di tumori solici mediante microparticelle di albumina incorporanti paclitaxel

Publications (1)

Publication Number	Publication Date
ZA200103755B true ZA200103755B (en)	2001-11-15

Family

ID=11445079

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200103755A ZA200103755B (en)	2000-05-18	2001-05-09	Use of paclitaxel stabilized with albumin for preparing a drug for the treatment of solid tumors and the drug obtained thereby.

Country Status (22)

Country	Link
US (1)	US6652884B2 (fr)
EP (1)	EP1155692B1 (fr)
JP (1)	JP2001354559A (fr)
KR (2)	KR20010105248A (fr)
CN (1)	CN1198609C (fr)
AT (1)	ATE267594T1 (fr)
AU (1)	AU781517B2 (fr)
BR (1)	BR0102040A (fr)
CA (1)	CA2345482A1 (fr)
DE (1)	DE60103453T2 (fr)
DK (1)	DK1155692T3 (fr)
ES (1)	ES2221874T3 (fr)
HU (1)	HU229909B1 (fr)
IL (1)	IL142674A0 (fr)
IT (1)	ITMI20001107A1 (fr)
MX (1)	MXPA01004980A (fr)
NO (1)	NO330511B1 (fr)
NZ (1)	NZ511201A (fr)
PT (1)	PT1155692E (fr)
RU (1)	RU2270003C2 (fr)
TR (1)	TR200101353A3 (fr)
ZA (1)	ZA200103755B (fr)

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CN1925874B (zh) *	2002-12-09	2014-12-17	阿布拉西斯生物科学有限责任公司	组合物和传递药剂的方法
US7670627B2 (en) *	2002-12-09	2010-03-02	Salvona Ip Llc	pH triggered targeted controlled release systems for the delivery of pharmaceutical active ingredients
US20040224019A1 (en) *	2004-03-03	2004-11-11	Adi Shefer	Oral controlled release system for targeted drug delivery into the cell and its nucleus for gene therapy, DNA vaccination, and administration of gene based drugs
AU2006249235B2 (en)	2004-05-14	2010-11-11	Abraxis Bioscience, Llc	Sparc and methods of use thereof
KR20070114753A (ko) *	2005-02-18	2007-12-04	아브락시스 바이오사이언스 인크.	치료제의 조합 및 투여 방식, 및 조합 요법
US20070166388A1 (en) *	2005-02-18	2007-07-19	Desai Neil P	Combinations and modes of administration of therapeutic agents and combination therapy
US8735394B2 (en)	2005-02-18	2014-05-27	Abraxis Bioscience, Llc	Combinations and modes of administration of therapeutic agents and combination therapy
LT3311805T (lt)	2005-08-31	2020-04-27	Abraxis Bioscience, Llc	Kompozicijos, apimančios silpnai vandenyje tirpius farmacinius agentus ir priešmikrobinius agentus
EP3527202A1 (fr)	2005-08-31	2019-08-21	Abraxis BioScience, LLC	Compositions et procédés de préparation de médicaments faiblement solubles dans l'eau ayant une stabilité améliorée
BRPI0617663A2 (pt) *	2005-10-21	2011-08-02	Panacea Biotec Ltd	composições aperfeiçoadas para terapia de cáncer
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EP3470071A1 (fr)	2006-12-14	2019-04-17	Abraxis BioScience, LLC	Thérapie contre le cancer du sein fondée sur le statut des récepteurs hormonaux, dans laquelle sont utilisées des nanoparticules comprenant du taxane
EP2131821B1 (fr)	2007-03-07	2018-05-09	Abraxis BioScience, LLC	Nanoparticule comprenant de la rapamycine et de l'albumine utilisée comme agent anticancéreux
US20100166869A1 (en) *	2007-05-03	2010-07-01	Desai Neil P	Methods and compositions for treating pulmonary hypertension
JP5579057B2 (ja)	2007-06-01	2014-08-27	アブラクシスバイオサイエンス，エルエルシー	再発性癌の処置のための方法および組成物
MX2010011165A (es) *	2008-04-10	2011-02-22	Abraxis Bioscience Llc	Composiciones de derivados de taxano hidrofobos y sus usos.
KR101090505B1 (ko) *	2008-12-30	2011-12-06	최은아	난담반을 포함하는 암 예방 및 치료용 조성물
PT2419732T (pt)	2009-04-15	2019-12-24	Abraxis Bioscience Llc	Composições e métodos de nanopartículas isentas de priões
NZ602382A (en)	2010-03-26	2014-11-28	Abraxis Bioscience Llc	Methods of treatment of hepatocellular carcinoma
EP3141245A1 (fr)	2010-03-29	2017-03-15	Abraxis BioScience, LLC	Méthodes de traitement du cancer
MX2012011155A (es)	2010-03-29	2012-12-05	Abraxis Bioscience Llc	Metodos para mejorar suministros de farmacos y efectividad de agentes terapeuticos.
MX347225B (es)	2010-06-04	2017-04-19	Abraxis Bioscience Llc *	Metodos de tratamiento contra el cancer pancreatico.
KR101970342B1 (ko)	2011-04-28	2019-04-18	아브락시스 바이오사이언스, 엘엘씨	나노입자 조성물의 혈관내 전달 및 그의 용도
EP3560486A1 (fr)	2011-12-14	2019-10-30	Abraxis BioScience, LLC	Utilisation d'excipients polymères pour la lyophilisation ou la congélation de particules
US9149455B2 (en)	2012-11-09	2015-10-06	Abraxis Bioscience, Llc	Methods of treating melanoma
US9511046B2 (en)	2013-01-11	2016-12-06	Abraxis Bioscience, Llc	Methods of treating pancreatic cancer
EP3698784A1 (fr)	2013-03-12	2020-08-26	Abraxis BioScience, LLC	Procédés de traitement du cancer du poumon
JP6387389B2 (ja) *	2013-03-13	2018-09-05	アブラクシスバイオサイエンス，エルエルシー	小児充実性腫瘍の処置の方法
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US10527604B1 (en)	2015-03-05	2020-01-07	Abraxis Bioscience, Llc	Methods of assessing suitability of use of pharmaceutical compositions of albumin and paclitaxel
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2000
- 2000-05-18 IT IT2000MI001107A patent/ITMI20001107A1/it unknown
2001
- 2001-04-17 US US09/835,384 patent/US6652884B2/en not_active Expired - Lifetime
- 2001-04-18 IL IL14267401A patent/IL142674A0/xx active IP Right Grant
- 2001-04-19 NZ NZ511201A patent/NZ511201A/xx not_active IP Right Cessation
- 2001-04-20 AU AU38765/01A patent/AU781517B2/en not_active Expired
- 2001-04-24 JP JP2001126061A patent/JP2001354559A/ja active Pending
- 2001-04-27 DE DE60103453T patent/DE60103453T2/de not_active Expired - Lifetime
- 2001-04-27 DK DK01110509T patent/DK1155692T3/da active
- 2001-04-27 EP EP01110509A patent/EP1155692B1/fr not_active Expired - Lifetime
- 2001-04-27 CA CA002345482A patent/CA2345482A1/fr not_active Abandoned
- 2001-04-27 PT PT01110509T patent/PT1155692E/pt unknown
- 2001-04-27 ES ES01110509T patent/ES2221874T3/es not_active Expired - Lifetime
- 2001-04-27 AT AT01110509T patent/ATE267594T1/de active
- 2001-05-09 ZA ZA200103755A patent/ZA200103755B/xx unknown
- 2001-05-15 TR TR2001/01353A patent/TR200101353A3/tr unknown
- 2001-05-16 NO NO20012409A patent/NO330511B1/no not_active IP Right Cessation
- 2001-05-17 KR KR1020010026970A patent/KR20010105248A/ko not_active Ceased
- 2001-05-17 MX MXPA01004980A patent/MXPA01004980A/es active IP Right Grant
- 2001-05-17 RU RU2001113688/15A patent/RU2270003C2/ru active
- 2001-05-17 HU HU0102039A patent/HU229909B1/hu unknown
- 2001-05-18 CN CNB011192585A patent/CN1198609C/zh not_active Ceased
- 2001-05-18 BR BR0102040-4A patent/BR0102040A/pt not_active Application Discontinuation
2008
- 2008-09-26 KR KR1020080094590A patent/KR20080091747A/ko not_active Ceased

Also Published As

Publication number	Publication date
RU2270003C2 (ru)	2006-02-20
NO330511B1 (no)	2011-05-09
PT1155692E (pt)	2004-09-30
CN1324613A (zh)	2001-12-05
EP1155692B1 (fr)	2004-05-26
HUP0102039A2 (hu)	2002-05-29
HU229909B1 (en)	2014-12-29
ES2221874T3 (es)	2005-01-16
TR200101353A2 (tr)	2001-12-21
DE60103453D1 (de)	2004-07-01
JP2001354559A (ja)	2001-12-25
AU781517B2 (en)	2005-05-26
CA2345482A1 (fr)	2001-11-18
HUP0102039A3 (en)	2002-12-28
US6652884B2 (en)	2003-11-25
HK1040368A1 (en)	2002-06-07
MXPA01004980A (es)	2002-08-06
TR200101353A3 (tr)	2001-12-21
NO20012409L (no)	2001-11-19
ITMI20001107A0 (it)	2000-05-18
BR0102040A (pt)	2002-03-19
ITMI20001107A1 (it)	2001-11-18
CN1198609C (zh)	2005-04-27
AU3876501A (en)	2001-11-22
NZ511201A (en)	2002-11-26
ATE267594T1 (de)	2004-06-15
US20010046961A1 (en)	2001-11-29
HU0102039D0 (en)	2001-07-30
IL142674A0 (en)	2002-03-10
EP1155692A1 (fr)	2001-11-21
DK1155692T3 (da)	2004-08-09
KR20080091747A (ko)	2008-10-14
KR20010105248A (ko)	2001-11-28
NO20012409D0 (no)	2001-05-16
DE60103453T2 (de)	2005-06-23

Publication	Publication Date	Title
ZA200103755B (en)	2001-11-15	Use of paclitaxel stabilized with albumin for preparing a drug for the treatment of solid tumors and the drug obtained thereby.
IL152754A0 (en)	2003-06-24	Quinazoline derivatives for the treatment of tumours
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DE60117859D1 (de)	2006-05-04	HARNSTOFFSUBSTITUIERTE IMIDAZOCHINOLINETHER und Arzneimittel, die diese umfassen.
BR0207378A (pt)	2004-06-15	Tratamento de câncer
EE200300212A (et)	2003-08-15	Ravimite kombinatsioonid (näiteks kloorpromasiin ja pentamidiin) neoplastiliste haiguste raviks
BR0014930B1 (pt)	2009-01-13	cÂnula.
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