ZA200207576B - IL-8 receptor antagonists. - Google Patents

IL-8 receptor antagonists. Download PDF

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Publication number
ZA200207576B
ZA200207576B ZA200207576A ZA200207576A ZA200207576B ZA 200207576 B ZA200207576 B ZA 200207576B ZA 200207576 A ZA200207576 A ZA 200207576A ZA 200207576 A ZA200207576 A ZA 200207576A ZA 200207576 B ZA200207576 B ZA 200207576B
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South Africa
Prior art keywords
hydroxy
crgrg
cyanoguanidine
chloro
alkyl
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ZA200207576A
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English (en)
Inventor
Palovich Michael Robert
Katherine Louisa Widdowson
Hong Nie
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Smithkline Beecham Corp
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Publication of ZA200207576B publication Critical patent/ZA200207576B/en

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AR029361A1 (es) * 1999-05-28 2003-06-25 Smithkline Beecham Corp Compuestos de guanidina ciclicas antagonistas de los receptores de la il- 8, composicion farmaceutica que los comprende y el uso de los mismos para la manufactura de un medicamento
AR041834A1 (es) * 2002-10-29 2005-06-01 Smithkline Beecham Corp Compuesto de difenilurea sustituido con sulfonamida, composicion farmaceutica que lo comprende y su uso para preparar dicha composicion
WO2005113534A2 (fr) 2004-05-12 2005-12-01 Schering Corporation Antagonistes de chimiokines cxcr1 et cxcr2
WO2006043950A1 (fr) * 2004-10-20 2006-04-27 Smithkline Beecham Corporation Antagonistes du récepteur il-8
AU2007240365B2 (en) * 2006-04-21 2011-12-15 Glaxosmithkline Llc IL-8 receptor antagonists
US8097626B2 (en) * 2006-04-21 2012-01-17 Glaxosmithkline Llc IL-8 receptor antagonists
CL2007001829A1 (es) * 2006-06-23 2008-01-25 Smithkline Beecham Corp P-toluensulfonato de n-[4-cloro-2-hidroxi-3-(piperazina-1-sulfonil)fenil]-n-(2-cloro-3-fluorofenil)urea;procedimiento de preparacion;composicion farmaceutica;combinacion farmaceutica;y uso en el tratamiento de una enfermedad mediada por la quiimioquina il-8, tales como asma y epoc.
US20090131329A1 (en) * 2007-09-14 2009-05-21 Edmund John Miller Treatment for allograft rejection
RU2593759C2 (ru) * 2010-09-03 2016-08-10 ФОРМА ТиЭм, ЭлЭлСИ Гуанидиновые соединения и композиции для ингибирования nampt
US8648070B2 (en) 2010-12-17 2014-02-11 Boehringer Ingelheim International Gmbh Bicyclic ring system substituted sulfonamide functionalised phenols as medicaments
IN2014DN09251A (fr) * 2012-05-08 2015-07-10 Ishihara Sangyo Kaisha
CA3128946A1 (fr) 2019-02-07 2020-08-13 Bayer Aktiengesellschaft 3-amino-2-[2-(acylamino)pyridin-4-yl]-1,5-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one en tant qu'inhibiteurs de csnk1

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EP0809492A4 (fr) * 1995-02-17 2007-01-24 Smithkline Beecham Corp Antagonistes des recepteurs d'il-8
AR008290A1 (es) 1996-08-15 1999-12-29 Smithkline Beecham Corp Nuevos compuestos que contienen guanidina utiles como antagonistas de los receptores de il-8, composiciones farmaceuticas que los contienenprocedimiento para la preparacion de dichos compuestos y procedimiento para la preparacion de intermediarios.
KR100642184B1 (ko) * 1998-09-23 2006-11-10 암젠 인크 아릴술폰아닐리드 우레아
UY25842A1 (es) * 1998-12-16 2001-04-30 Smithkline Beecham Corp Antagonistas de receptores de il-8

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IL151210A0 (en) 2003-04-10
SK13682002A3 (sk) 2003-06-03
EP1272175A2 (fr) 2003-01-08
MA25739A1 (fr) 2003-04-01
EA200201019A1 (ru) 2003-12-25
HUP0302614A2 (hu) 2003-11-28
EP1272175A4 (fr) 2005-08-31
JP2004508287A (ja) 2004-03-18
MY128154A (en) 2007-01-31
DZ3333A1 (fr) 2001-10-04
AP1548A (en) 2006-01-16
OA12235A (en) 2003-11-06
HUP0302614A3 (en) 2005-05-30
UY26627A1 (es) 2001-09-28
MXPA02009355A (es) 2003-02-12
PL205103B1 (pl) 2010-03-31
NO20024554D0 (no) 2002-09-23
CA2403787A1 (fr) 2001-10-04
PL366315A1 (en) 2005-01-24
BG107035A (bg) 2003-04-30
US6680317B2 (en) 2004-01-20
WO2001072960A3 (fr) 2002-02-21
CZ20023192A3 (cs) 2003-02-12
ATE464893T1 (de) 2010-05-15
CN1452483A (zh) 2003-10-29
HK1053789A1 (zh) 2003-11-07
EP1272175B1 (fr) 2010-04-21
BR0108867A (pt) 2005-02-09
AR031101A1 (es) 2003-09-10
PE20020839A1 (es) 2002-12-04
AP2002002599A0 (en) 2002-09-30
WO2001072960A2 (fr) 2001-10-04
DE60141896D1 (de) 2010-06-02
AU2001249354A1 (en) 2001-10-08
KR20040014901A (ko) 2004-02-18
ES2344587T3 (es) 2010-09-01
US20030216375A1 (en) 2003-11-20

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