ZA200410324B - IgG fc/HIV-gp120/C3d fusion protein - Google Patents

IgG fc/HIV-gp120/C3d fusion protein Download PDF

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Publication number
ZA200410324B
ZA200410324B ZA200410324A ZA200410324A ZA200410324B ZA 200410324 B ZA200410324 B ZA 200410324B ZA 200410324 A ZA200410324 A ZA 200410324A ZA 200410324 A ZA200410324 A ZA 200410324A ZA 200410324 B ZA200410324 B ZA 200410324B
Authority
ZA
South Africa
Prior art keywords
component
fusion protein
hiv
hiv envelope
protein according
Prior art date
Application number
ZA200410324A
Other languages
English (en)
Inventor
Barton F Haynes
David C Montefiori
Original Assignee
Univ Duke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Duke filed Critical Univ Duke
Publication of ZA200410324B publication Critical patent/ZA200410324B/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/20Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA200410324A 2002-07-23 2004-12-22 IgG fc/HIV-gp120/C3d fusion protein ZA200410324B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US39760502P 2002-07-23 2002-07-23

Publications (1)

Publication Number Publication Date
ZA200410324B true ZA200410324B (en) 2006-07-26

Family

ID=30771086

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200410324A ZA200410324B (en) 2002-07-23 2004-12-22 IgG fc/HIV-gp120/C3d fusion protein

Country Status (13)

Country Link
US (1) US20060014148A1 (de)
EP (2) EP1523492A4 (de)
JP (2) JP2006509496A (de)
KR (1) KR20050036960A (de)
CN (1) CN100366631C (de)
AU (1) AU2003256671B2 (de)
BR (1) BR0312808A (de)
CA (1) CA2493706A1 (de)
IL (1) IL166343A0 (de)
MX (1) MXPA05000874A (de)
NZ (1) NZ537345A (de)
WO (1) WO2004009785A2 (de)
ZA (1) ZA200410324B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004503205A (ja) 2000-02-04 2004-02-05 デューク・ユニバーシティー ヒト免疫不全ウイルスワクチン
JP2004511444A (ja) 2000-09-22 2004-04-15 デューク・ユニバーシティー 免疫原
US7033593B2 (en) 2000-09-22 2006-04-25 Duke University Immunogen comprising an HIV envelope protein, a ligand and H2 peptide
WO2003039470A2 (en) 2001-11-07 2003-05-15 Duke University Polyvalent immunogen of hiv
US7195768B2 (en) 2001-11-07 2007-03-27 Duke University Polyvalent immunogen
US7172761B2 (en) 2001-11-07 2007-02-06 Duke University Polyvalent immunogen
GB0614780D0 (en) * 2006-07-25 2006-09-06 Ucb Sa Biological products
WO2009137632A2 (en) * 2008-05-06 2009-11-12 Government Of The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Hiv immunogen and method of making and using same
WO2010045613A1 (en) * 2008-10-16 2010-04-22 New York Blood Center Immunoenhancer-linked oligomeric hiv vaccines
US9592287B2 (en) 2009-10-09 2017-03-14 New York Blood Center, Inc. Immunopotentiator-linked oligomeric influenza immunogenic compositions
WO2011126576A2 (en) * 2010-04-09 2011-10-13 Duke University Genetic signatures in the envelope glycoprotein of hiv-1
EP2578309B1 (de) 2010-05-24 2017-12-13 Incorporated Administrative Agency National Agriculture And Food Research Organization Granulierverfahren
AU2012311238A1 (en) * 2011-09-23 2014-04-17 University Of Oslo Vaccibodies targeted to cross-presenting dendritic cells
EP2706356A1 (de) * 2012-09-06 2014-03-12 Laboratorios Del. Dr. Esteve, S.A. Verfahren zur Identifizierung HIV-neutralisierender Antikörper
JP6955487B2 (ja) * 2015-09-24 2021-10-27 アブビトロ, エルエルシー Hiv抗体組成物および使用方法
KR20230019227A (ko) * 2017-11-17 2023-02-07 그리폴스 다이어그노스틱 솔루션즈 인크. 신규한 포유동물 발현 인간 면역결핍 바이러스 외피 단백질 항원

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225538A (en) * 1989-02-23 1993-07-06 Genentech, Inc. Lymphocyte homing receptor/immunoglobulin fusion proteins
EP0699077B1 (de) * 1993-05-07 2001-10-31 Akzo Nobel N.V. Hiv immunogene komplexe
JP2004511444A (ja) 2000-09-22 2004-04-15 デューク・ユニバーシティー 免疫原
WO2003039470A2 (en) 2001-11-07 2003-05-15 Duke University Polyvalent immunogen of hiv

Also Published As

Publication number Publication date
AU2003256671A1 (en) 2004-02-09
CA2493706A1 (en) 2004-01-29
EP1523492A2 (de) 2005-04-20
US20060014148A1 (en) 2006-01-19
CN100366631C (zh) 2008-02-06
CN1668633A (zh) 2005-09-14
NZ537345A (en) 2007-12-21
KR20050036960A (ko) 2005-04-20
JP2006509496A (ja) 2006-03-23
MXPA05000874A (es) 2005-03-23
WO2004009785A2 (en) 2004-01-29
JP2010057490A (ja) 2010-03-18
IL166343A0 (en) 2006-01-16
EP1523492A4 (de) 2006-05-10
AU2003256671B2 (en) 2008-10-16
WO2004009785A3 (en) 2004-08-05
EP2374811A1 (de) 2011-10-12
BR0312808A (pt) 2005-04-19

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