ZA200501876B - A delivery system and a manufacturing process of adelivery system - Google Patents

A delivery system and a manufacturing process of adelivery system Download PDF

Info

Publication number: ZA200501876B
Authority: ZA; South Africa
Prior art keywords: capsule; delivery system; pharmaceutical composition; body construction; illustrates
Prior art date: 2002-09-18

Application number

ZA200501876A

Other languages

English (en)

Inventor

Esa Hallinen

Heikki Lyytikainen

Pentti Jarvela

Ilkka Kivi

Original Assignee

Schering Oy

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-09-18

Filing date

2005-03-04

Publication date

2006-05-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=31896871&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200501876(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2005-03-04 Application filed by Schering Oy filed Critical Schering Oy

2006-05-31 Publication of ZA200501876B publication Critical patent/ZA200501876B/en

Links

238000004519 manufacturing process Methods 0.000 title claims abstract description 26
239000002775 capsule Substances 0.000 claims abstract description 136
238000010276 construction Methods 0.000 claims abstract description 31
239000008194 pharmaceutical composition Substances 0.000 claims abstract description 28
239000013543 active substance Substances 0.000 claims description 11
238000000034 method Methods 0.000 claims description 11
238000002347 injection Methods 0.000 claims description 9
239000007924 injection Substances 0.000 claims description 9
229920000249 biocompatible polymer Polymers 0.000 claims description 3
-1 polyethylene Polymers 0.000 description 21
239000000203 mixture Substances 0.000 description 10
239000000463 material Substances 0.000 description 9
229920001971 elastomer Polymers 0.000 description 8
239000000806 elastomer Substances 0.000 description 8
239000012528 membrane Substances 0.000 description 8
229920001577 copolymer Polymers 0.000 description 7
VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 description 6
239000005977 Ethylene Substances 0.000 description 5
239000003814 drug Substances 0.000 description 5
229940079593 drug Drugs 0.000 description 5
230000001681 protective effect Effects 0.000 description 5
210000004291 uterus Anatomy 0.000 description 5
239000000853 adhesive Substances 0.000 description 4
230000001070 adhesive effect Effects 0.000 description 4
229920001296 polysiloxane Polymers 0.000 description 4
239000002904 solvent Substances 0.000 description 4
229940117958 vinyl acetate Drugs 0.000 description 4
RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 3
XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical compound CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 description 3
230000015572 biosynthetic process Effects 0.000 description 3
238000001746 injection moulding Methods 0.000 description 3
229920000435 poly(dimethylsiloxane) Polymers 0.000 description 3
229920000573 polyethylene Polymers 0.000 description 3
229920000642 polymer Polymers 0.000 description 3
229920000131 polyvinylidene Polymers 0.000 description 3
239000002033 PVDF binder Substances 0.000 description 2
239000004743 Polypropylene Substances 0.000 description 2
230000006866 deterioration Effects 0.000 description 2
235000013870 dimethyl polysiloxane Nutrition 0.000 description 2
229920003023 plastic Polymers 0.000 description 2
239000004033 plastic Substances 0.000 description 2
BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
229920000233 poly(alkylene oxides) Polymers 0.000 description 2
229920001155 polypropylene Polymers 0.000 description 2
239000004810 polytetrafluoroethylene Substances 0.000 description 2
229920001343 polytetrafluoroethylene Polymers 0.000 description 2
229920002689 polyvinyl acetate Polymers 0.000 description 2
239000011118 polyvinyl acetate Substances 0.000 description 2
229920002981 polyvinylidene fluoride Polymers 0.000 description 2
239000003488 releasing hormone Substances 0.000 description 2
229920002379 silicone rubber Polymers 0.000 description 2
238000003466 welding Methods 0.000 description 2
VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
239000004709 Chlorinated polyethylene Substances 0.000 description 1
102000008186 Collagen Human genes 0.000 description 1
108010035532 Collagen Proteins 0.000 description 1
JPVYNHNXODAKFH-UHFFFAOYSA-N Cu2+ Chemical compound [Cu+2] JPVYNHNXODAKFH-UHFFFAOYSA-N 0.000 description 1
IMROMDMJAWUWLK-UHFFFAOYSA-N Ethenol Chemical compound OC=C IMROMDMJAWUWLK-UHFFFAOYSA-N 0.000 description 1
239000004952 Polyamide Substances 0.000 description 1
229920002732 Polyanhydride Polymers 0.000 description 1
239000005062 Polybutadiene Substances 0.000 description 1
239000004698 Polyethylene Substances 0.000 description 1
229920000954 Polyglycolide Polymers 0.000 description 1
229920001710 Polyorthoester Polymers 0.000 description 1
239000004793 Polystyrene Substances 0.000 description 1
239000004372 Polyvinyl alcohol Substances 0.000 description 1
NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
DQXBYHZEEUGOBF-UHFFFAOYSA-N but-3-enoic acid;ethene Chemical compound C=C.OC(=O)CC=C DQXBYHZEEUGOBF-UHFFFAOYSA-N 0.000 description 1
229920005549 butyl rubber Polymers 0.000 description 1
239000003054 catalyst Substances 0.000 description 1
239000003795 chemical substances by application Substances 0.000 description 1
229920001436 collagen Polymers 0.000 description 1
229910001431 copper ion Inorganic materials 0.000 description 1
238000004132 cross linking Methods 0.000 description 1
239000003431 cross linking reagent Substances 0.000 description 1
230000007423 decrease Effects 0.000 description 1
230000003247 decreasing effect Effects 0.000 description 1
239000004205 dimethyl polysiloxane Substances 0.000 description 1
KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 description 1
239000013013 elastic material Substances 0.000 description 1
239000013536 elastomeric material Substances 0.000 description 1
229920005558 epichlorohydrin rubber Polymers 0.000 description 1
150000002148 esters Chemical class 0.000 description 1
239000005038 ethylene vinyl acetate Substances 0.000 description 1
230000003054 hormonal effect Effects 0.000 description 1
239000000017 hydrogel Substances 0.000 description 1
229920001477 hydrophilic polymer Polymers 0.000 description 1
238000007654 immersion Methods 0.000 description 1
230000001788 irregular Effects 0.000 description 1
230000007794 irritation Effects 0.000 description 1
238000002483 medication Methods 0.000 description 1
229910052751 metal Inorganic materials 0.000 description 1
239000002184 metal Substances 0.000 description 1
125000005395 methacrylic acid group Chemical class 0.000 description 1
229910052697 platinum Inorganic materials 0.000 description 1
229920001084 poly(chloroprene) Polymers 0.000 description 1
229920001200 poly(ethylene-vinyl acetate) Polymers 0.000 description 1
229920000747 poly(lactic acid) Polymers 0.000 description 1
229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
229920002647 polyamide Polymers 0.000 description 1
229920002857 polybutadiene Polymers 0.000 description 1
239000004417 polycarbonate Substances 0.000 description 1
229920000515 polycarbonate Polymers 0.000 description 1
229920000728 polyester Polymers 0.000 description 1
229920000139 polyethylene terephthalate Polymers 0.000 description 1
239000005020 polyethylene terephthalate Substances 0.000 description 1
229920001195 polyisoprene Polymers 0.000 description 1
229920000193 polymethacrylate Polymers 0.000 description 1
229920000306 polymethylpentene Polymers 0.000 description 1
239000011116 polymethylpentene Substances 0.000 description 1
229920002223 polystyrene Polymers 0.000 description 1
229920002635 polyurethane Polymers 0.000 description 1
239000004814 polyurethane Substances 0.000 description 1
229920002451 polyvinyl alcohol Polymers 0.000 description 1
229920000915 polyvinyl chloride Polymers 0.000 description 1
239000004800 polyvinyl chloride Substances 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 description 1
125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 description 1
239000000243 solution Substances 0.000 description 1
229920001897 terpolymer Polymers 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
- A61F6/06—Contraceptive devices; Pessaries; Applicators therefor for use by females
- A61F6/14—Contraceptive devices; Pessaries; Applicators therefor for use by females intra-uterine type

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Reproductive Health (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Heart & Thoracic Surgery (AREA)
Vascular Medicine (AREA)
Epidemiology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Medicinal Preparation (AREA)
Medical Preparation Storing Or Oral Administration Devices (AREA)
Vending Machines For Individual Products (AREA)
Adjustment And Processing Of Grains (AREA)
Infusion, Injection, And Reservoir Apparatuses (AREA)
Orthopedics, Nursing, And Contraception (AREA)
Macromonomer-Based Addition Polymer (AREA)
Pyrane Compounds (AREA)
Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
Automatic Assembly (AREA)
Paper (AREA)
Reverberation, Karaoke And Other Acoustics (AREA)
Apparatuses And Processes For Manufacturing Resistors (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

ZA200501876A 2002-09-18 2005-03-04 A delivery system and a manufacturing process of adelivery system ZA200501876B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP02020869A EP1400258A1 (en)	2002-09-18	2002-09-18	Pharmaceutical composition delivery device and its manufacturing process

Publications (1)

Publication Number	Publication Date
ZA200501876B true ZA200501876B (en)	2006-05-31

Family

ID=31896871

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200501876A ZA200501876B (en)	2002-09-18	2005-03-04	A delivery system and a manufacturing process of adelivery system

Country Status (26)

Country	Link
US (1)	US7252839B2 (pt)
EP (2)	EP1400258A1 (pt)
JP (1)	JP4382668B2 (pt)
KR (1)	KR100827635B1 (pt)
CN (1)	CN1310627C (pt)
AT (1)	ATE387898T1 (pt)
AU (1)	AU2003258752B2 (pt)
BR (1)	BRPI0314287B8 (pt)
CA (1)	CA2499187C (pt)
CR (1)	CR7709A (pt)
DE (1)	DE60319549T3 (pt)
DK (1)	DK1539063T4 (pt)
EC (1)	ECSP055686A (pt)
ES (1)	ES2300650T5 (pt)
HR (1)	HRP20050340B1 (pt)
IL (2)	IL166787A0 (pt)
MX (1)	MXPA05002718A (pt)
NO (1)	NO331466B1 (pt)
NZ (1)	NZ538275A (pt)
PL (1)	PL214245B1 (pt)
PT (1)	PT1539063E (pt)
RU (1)	RU2297810C2 (pt)
SI (1)	SI1539063T2 (pt)
UA (1)	UA77859C2 (pt)
WO (1)	WO2004026196A1 (pt)
ZA (1)	ZA200501876B (pt)

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USD525705S1 (en) *	2004-01-23	2006-07-25	Familplan Consulting Ltd Oy	Intrauterine device for releasing steroids
FR2881046A1 (fr) *	2005-01-25	2006-07-28	7 Med Ind Sa	Procede de fabrication d'un reservoir contenant une substance active diffusant a travers le reservoir et installation pour sa mise en oeuvre
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NL1030795C2 (nl) *	2005-12-27	2007-06-28	Willem Arthur Adriaan Van Os	Intra-uterine inrichting en huls voor het inbrengen daarvan in de uterus.
US10004584B2 (en)	2006-07-10	2018-06-26	First Quality Hygienic, Inc.	Resilient intravaginal device
US8177706B2 (en) *	2006-07-10	2012-05-15	Mcneil-Ppc, Inc.	Method of treating urinary incontinence
US10219884B2 (en)	2006-07-10	2019-03-05	First Quality Hygienic, Inc.	Resilient device
EP2057972A1 (en)	2007-11-07	2009-05-13	N.V. Organon	Intrauterine deposit
EA201070703A1 (ru)	2007-12-11	2010-12-30	Массачусетс Инститьют Оф Текнолоджи	Имплантируемое устройство для доставки лекарства и способы лечения мочевого пузыря и других полостей тела или трубчатых органов
FR2927798B1 (fr) *	2008-02-25	2011-03-04	C L Investissements	Procede de fabrication d'un dispositif contraceptif intra-uterin et installation pour la mise en oeuvre de ce procede
FR2927799B1 (fr) *	2008-02-25	2011-03-04	C L Investissements	Procede de mise en place d'une membrane autour d'un element contenant une substance active et installation de mise en oeuvre de ce procede
FI20080524A0 (fi)	2008-09-17	2008-09-17	Bayer Schering Pharma Oy	Insertteri
CN102159162B (zh)	2008-09-17	2013-04-24	拜耳公司	插入器
US11992431B2 (en)	2008-09-17	2024-05-28	Bayer Oy	Inserter
FI20080523A0 (fi)	2008-09-17	2008-09-17	Bayer Schering Pharma Oy	Insertteri
EP2352544A4 (en) *	2008-11-07	2013-12-25	Combinent Biomedical Systems Inc	DEVICES AND METHOD FOR THE TREATMENT AND / OR PREVENTION OF DISEASES
EP2395941B1 (en) *	2009-02-11	2017-01-11	Nanyang Technological University	Multi-layered surgical prosthesis
US8568374B2 (en) *	2009-05-04	2013-10-29	Merck Sharp & Dohme B.V.	Intrauterine system
WO2011117856A1 (en) *	2010-03-21	2011-09-29	Soroker, Eran	Intrauterine device and inserter for the same
ZA201107786B (en) *	2010-10-26	2012-07-25	Maurice Roger Pope	An inhibotor of pathogens
WO2014023797A1 (en)	2012-08-09	2014-02-13	Odyssea Pharma S.P.R.L.	Intrauterine device
EP2708213A1 (en) *	2012-09-13	2014-03-19	PAT&Co bvba	Multipurpose ethylene vinyl acetate fibrous drug delivery systems for long-term implantation or insertion
CN103784244B (zh) *	2012-10-30	2016-03-23	吴江永元生物科技有限公司	一种子宫内植入物
ES2949133T3 (es) *	2013-03-08	2023-09-25	Li Galli B V I O	Sistema de diagnóstico y/o administración de fármacos vaginales
US11007143B2 (en)	2013-03-15	2021-05-18	Cda Research Group, Inc.	Topical copper ion treatments and methods of treatment using topical copper ion treatments in the oral-respiratory-otic areas of the body
US10398733B2 (en)	2013-03-15	2019-09-03	Cda Research Group, Inc.	Topical copper ion treatments and methods of treatment using topical copper ion treatments in the dermatological areas of the body
US11083750B2 (en)	2013-03-15	2021-08-10	Cda Research Group, Inc.	Methods of treatment using topical copper ion formulations
US11000545B2 (en)	2013-03-15	2021-05-11	Cda Research Group, Inc.	Copper ion compositions and methods of treatment for conditions caused by coronavirus and influenza
US11318089B2 (en)	2013-03-15	2022-05-03	Cda Research Group, Inc.	Topical copper ion treatments and methods of making topical copper ion treatments for use in various anatomical areas of the body
US12318406B2 (en)	2013-03-15	2025-06-03	Cda Research Group, Inc.	Methods of treatment using topical copper ion formulations
US20150182382A1 (en) *	2013-12-27	2015-07-02	Custom Protect Ear, Inc.	Pre-lubricated earplugs and the method of production thereof
CN104001260A (zh) *	2014-06-10	2014-08-27	中国医学科学院生物医学工程研究所	可以提高药物释放速度的宫内药物释放体
EP3191030B1 (en)	2014-09-09	2021-04-14	Qpharma AB	An insertable mould assembly, an injection moulding tool therefore, a substrate and an injection moulding method
US10017115B2 (en) *	2015-11-11	2018-07-10	Ford Global Technologies, Llc	Trailer monitoring system and method
WO2019200694A1 (zh) *	2018-04-19	2019-10-24	易浦润（上海）生物技术有限公司	一种宫腔内具备重新激活内膜基底层功能的弹性膜及其制备方法
JP2020047353A (ja)	2018-09-20	2020-03-26	キオクシア株式会社	メモリシステム
US11193184B2 (en)	2019-02-22	2021-12-07	Cda Research Group, Inc.	System for use in producing a metal ion suspension and process of using same
TW202142199A (zh) *	2020-01-24	2021-11-16	芬蘭商拜耳股份有限公司	具有護套之子宮內系統
TW202131879A (zh) *	2020-01-24	2021-09-01	芬蘭商拜耳股份有限公司	具備鎖定部件之子宮內系統
WO2025110136A1 (ja) *	2023-11-21	2025-05-30	国立大学法人東京科学大学	胚移植デバイス

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2002
- 2002-09-18 EP EP02020869A patent/EP1400258A1/en not_active Withdrawn
2003
- 2003-04-09 UA UAA200503581A patent/UA77859C2/uk unknown
- 2003-09-04 AU AU2003258752A patent/AU2003258752B2/en not_active Expired
- 2003-09-04 MX MXPA05002718A patent/MXPA05002718A/es active IP Right Grant
- 2003-09-04 CN CNB038220083A patent/CN1310627C/zh not_active Expired - Lifetime
- 2003-09-04 HR HRP20050340AA patent/HRP20050340B1/hr not_active IP Right Cessation
- 2003-09-04 IL IL16678703A patent/IL166787A0/xx active IP Right Grant
- 2003-09-04 AT AT03797325T patent/ATE387898T1/de active
- 2003-09-04 NZ NZ538275A patent/NZ538275A/en not_active IP Right Cessation
- 2003-09-04 BR BRPI0314287A patent/BRPI0314287B8/pt not_active IP Right Cessation
- 2003-09-04 SI SI200331232T patent/SI1539063T2/sl unknown
- 2003-09-04 DK DK03797325.2T patent/DK1539063T4/da active
- 2003-09-04 CA CA002499187A patent/CA2499187C/en not_active Expired - Fee Related
- 2003-09-04 WO PCT/FI2003/000647 patent/WO2004026196A1/en not_active Ceased
- 2003-09-04 EP EP03797325A patent/EP1539063B2/en not_active Expired - Lifetime
- 2003-09-04 PT PT03797325T patent/PT1539063E/pt unknown
- 2003-09-04 US US10/528,237 patent/US7252839B2/en not_active Expired - Lifetime
- 2003-09-04 ES ES03797325T patent/ES2300650T5/es not_active Expired - Lifetime
- 2003-09-04 PL PL374112A patent/PL214245B1/pl unknown
- 2003-09-04 RU RU2005111234/14A patent/RU2297810C2/ru active
- 2003-09-04 KR KR1020057004535A patent/KR100827635B1/ko not_active Expired - Lifetime
- 2003-09-04 DE DE60319549T patent/DE60319549T3/de not_active Expired - Lifetime
- 2003-09-04 JP JP2004537173A patent/JP4382668B2/ja not_active Expired - Lifetime
2005
- 2005-02-09 IL IL166787A patent/IL166787A/en unknown
- 2005-02-20 CR CR7709A patent/CR7709A/es unknown
- 2005-03-04 ZA ZA200501876A patent/ZA200501876B/en unknown
- 2005-03-18 EC EC2005005686A patent/ECSP055686A/es unknown
- 2005-04-15 NO NO20051858A patent/NO331466B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
BR0314287A (pt)	2005-07-26
IL166787A0 (en)	2006-01-15
CA2499187A1 (en)	2004-04-01
JP2005538791A (ja)	2005-12-22
DE60319549D1 (de)	2008-04-17
NO331466B1 (no)	2012-01-09
NO20051858L (no)	2005-04-15
PL214245B1 (pl)	2013-07-31
CN1681455A (zh)	2005-10-12
US20060016451A1 (en)	2006-01-26
IL166787A (en)	2011-02-28
MXPA05002718A (es)	2005-09-08
ECSP055686A (es)	2005-07-06
RU2297810C2 (ru)	2007-04-27
RU2005111234A (ru)	2006-01-20
SI1539063T1 (sl)	2008-08-31
EP1539063B1 (en)	2008-03-05
SI1539063T2 (sl)	2013-02-28
CA2499187C (en)	2007-11-20
JP4382668B2 (ja)	2009-12-16
HRP20050340B1 (hr)	2014-04-11
AU2003258752A1 (en)	2004-04-08
BRPI0314287B8 (pt)	2021-06-22
KR100827635B1 (ko)	2008-05-07
PL374112A1 (en)	2005-10-03
ES2300650T3 (es)	2008-06-16
DE60319549T3 (de)	2013-03-21
EP1539063A1 (en)	2005-06-15
AU2003258752B2 (en)	2008-03-06
DE60319549T2 (de)	2009-04-02
UA77859C2 (en)	2007-01-15
DK1539063T3 (da)	2008-06-09
NZ538275A (en)	2006-07-28
WO2004026196A1 (en)	2004-04-01
CR7709A (es)	2005-06-30
ES2300650T5 (es)	2013-01-04
EP1539063B2 (en)	2012-10-10
HRP20050340A2 (en)	2006-06-30
ATE387898T1 (de)	2008-03-15
EP1400258A1 (en)	2004-03-24
CN1310627C (zh)	2007-04-18
BR0314287B1 (pt)	2014-02-18
PT1539063E (pt)	2008-04-22
DK1539063T4 (da)	2013-02-04
KR20050057381A (ko)	2005-06-16
HK1076023A1 (en)	2006-01-06
US7252839B2 (en)	2007-08-07

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