ZA200607700B - Pharmaceutical formulations for dry powder inhalers comprising a low-dosage strength active ingredient - Google Patents

Pharmaceutical formulations for dry powder inhalers comprising a low-dosage strength active ingredient Download PDF

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Publication number
ZA200607700B
ZA200607700B ZA200607700A ZA200607700A ZA200607700B ZA 200607700 B ZA200607700 B ZA 200607700B ZA 200607700 A ZA200607700 A ZA 200607700A ZA 200607700 A ZA200607700 A ZA 200607700A ZA 200607700 B ZA200607700 B ZA 200607700B
Authority
ZA
South Africa
Prior art keywords
particles
microparticles
excipient
active ingredient
comprised
Prior art date
Application number
ZA200607700A
Other languages
English (en)
Inventor
Bilzi Roberto
Armanni Angela
Rastelli Roberto
Cocconi Daniela
Musa Rossella
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34962706&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200607700(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Publication of ZA200607700B publication Critical patent/ZA200607700B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA200607700A 2004-03-17 2005-03-16 Pharmaceutical formulations for dry powder inhalers comprising a low-dosage strength active ingredient ZA200607700B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04006430 2004-03-17

Publications (1)

Publication Number Publication Date
ZA200607700B true ZA200607700B (en) 2008-05-28

Family

ID=34962706

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200607700A ZA200607700B (en) 2004-03-17 2005-03-16 Pharmaceutical formulations for dry powder inhalers comprising a low-dosage strength active ingredient

Country Status (19)

Country Link
US (1) US8153104B2 (fr)
EP (1) EP1729728B1 (fr)
KR (1) KR20060130216A (fr)
CN (1) CN1942172B (fr)
AR (1) AR049010A1 (fr)
AU (1) AU2005224008B2 (fr)
BR (1) BRPI0508170A (fr)
CA (1) CA2560226C (fr)
ES (1) ES2566618T3 (fr)
JO (1) JO3102B1 (fr)
MA (1) MA28514B1 (fr)
MX (1) MXPA06010593A (fr)
NO (1) NO342481B1 (fr)
NZ (1) NZ549870A (fr)
PE (1) PE20060716A1 (fr)
RU (1) RU2371171C2 (fr)
TN (1) TNSN06277A1 (fr)
WO (1) WO2005089717A1 (fr)
ZA (1) ZA200607700B (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1944018A1 (fr) * 2007-01-10 2008-07-16 CHIESI FARMACEUTICI S.p.A. Particules micronisées comprenant des principes actifs agissant même à faible dose pour préparations en poudre pour inhalation
WO2008102128A2 (fr) * 2007-02-19 2008-08-28 Cipla Limited Combinaisons pharmaceutiques
EP2191821A1 (fr) * 2008-11-26 2010-06-02 CHIESI FARMACEUTICI S.p.A. Microparticles contenant une sel de 8-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]-2(1H)-quinolinone avec adhesion ameliorée pour l'inhalation de poudre sèche
TWI491416B (zh) * 2008-12-24 2015-07-11 Daiichi Sankyo Co Ltd 吸入用乾燥粉末醫藥組成物
CA2770714A1 (fr) * 2009-08-27 2011-03-17 Stc.Unm Procedes et systemes de dosage et d'enduction de poudres destinees a l'inhalation sur des particules supports
EP2360147A1 (fr) * 2010-02-22 2011-08-24 CHIESI FARMACEUTICI S.p.A. Procédé de préparation de particules crystallines d'un sel de 8-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino] ethyl]-2(1H)-quinolinone (carmoterol)
RU2585101C2 (ru) * 2010-04-01 2016-05-27 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Способ приготовления частиц носителя для сухих порошков для ингаляции
DE102011102614A1 (de) * 2011-05-27 2012-11-29 Roland Nied Verfahren zum Betrieb einer Strahlmühle sowie Strahlmühle
WO2013077830A1 (fr) * 2011-11-25 2013-05-30 Mahmut Bilgic Associations actives sur le plan synergique contenant du roflumilast et du carmotérol
MX368199B (es) * 2012-01-25 2019-09-24 Chiesi Farm Spa Formulación en polvo seco que comprende un corticoesteroide y un beta-adrenérgico para administración por inhalación.
WO2013128283A2 (fr) 2012-02-28 2013-09-06 Iceutica Holdings Inc. Bvi Compositions pharmaceutiques inhalables
US9763965B2 (en) 2012-04-13 2017-09-19 Glaxosmithkline Intellectual Property Development Limited Aggregate particles
JP5087182B1 (ja) * 2012-06-13 2012-11-28 クリニプロ株式会社 吸入用パウダーの製造方法
BR112015022831A2 (pt) * 2013-03-13 2017-08-22 Forest Laboratories Holdings Ltd Composições farmacêuticas micronizadas
GB201305825D0 (en) 2013-03-28 2013-05-15 Vectura Ltd New use
SI3569222T1 (sl) * 2013-07-11 2024-10-30 Chiesi Farmaceutici S.P.A. Formulacija suhega praška, obsegajoča antiholinergik, kortikosteroid in beta-adrenergik, za dajanje z inhalacijo
US9427376B2 (en) * 2013-10-10 2016-08-30 Chiesi Farmaceutici S.P.A. Process for preparing pharmaceutical formulations for inhalation comprising a high-dosage strength active ingredient
CN104800192A (zh) * 2014-01-27 2015-07-29 成都英诺新科技有限公司 一种罗氟司特吸入粉雾剂及制备方法
SG11201700536XA (en) 2014-09-09 2017-02-27 Vectura Ltd Formulation comprising glycopyrrolate, method and apparatus
US10583085B2 (en) * 2017-05-17 2020-03-10 Chiesi Farmaceutici S.P.A. Carrier particles for dry powder formulations for inhalation
CN109200034A (zh) * 2017-06-30 2019-01-15 正大天晴药业集团股份有限公司 一种可吸入干粉形式的组合物及其制备方法
GB201911517D0 (en) * 2019-08-12 2019-09-25 Verona Pharma Plc Pharmaceutical composition
CN114929359B (zh) * 2019-12-16 2024-12-24 西根公司 赋形剂的高效液相色谱量化
US20210353650A1 (en) * 2020-05-18 2021-11-18 Cai Gu Huang Pharmaceutical formulation containing remdesivir and its active metabolites for dry powder inhalation

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE94801T1 (de) 1990-01-29 1993-10-15 Ciba Geigy Ag Verfahren und vorrichtung zur dosierung eines feinkoernigen pulvers.
US6673335B1 (en) * 1992-07-08 2004-01-06 Nektar Therapeutics Compositions and methods for the pulmonary delivery of aerosolized medicaments
IS1796B (is) * 1993-06-24 2001-12-31 Ab Astra Fjölpeptíð lyfjablanda til innöndunar sem einnig inniheldur eykjaefnasamband
SE9700135D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
US20010006939A1 (en) 1997-10-03 2001-07-05 Ralph W. Niven Secretory leukocyte protease inhibitor dry powder pharmaceutical compositions
IT1309592B1 (it) 1999-03-05 2002-01-24 Chiesi Farma Spa Particelle veicolo modificate da utilizzarsi nella preparazione diformulazioni farmaceutiche sotto forma di polimeri per inalazione e
GB9925934D0 (en) * 1999-11-03 1999-12-29 Glaxo Group Ltd Novel apparatus and process
PE20011227A1 (es) * 2000-04-17 2002-01-07 Chiesi Farma Spa Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros
WO2002011695A2 (fr) * 2000-08-07 2002-02-14 Inhale Therapeutic Systems, Inc. Poudres a inhaler de proteines en faisceau a quatre helices sechees par atomisation presentant une agregation reduite au minimum
US6587025B2 (en) * 2001-01-31 2003-07-01 Vishay Dale Electronics, Inc. Side-by-side coil inductor
JP2009513531A (ja) 2003-07-11 2009-04-02 グラクソ グループ リミテッド 糖エステルを含む吸入可能医薬製剤
EP2080508A1 (fr) * 2008-01-15 2009-07-22 CHIESI FARMACEUTICI S.p.A. Formulation de poudre sèche comprenant un médicament anticholinérgique

Also Published As

Publication number Publication date
EP1729728B1 (fr) 2016-03-16
RU2006133038A (ru) 2008-03-20
EP1729728A1 (fr) 2006-12-13
CA2560226C (fr) 2013-07-23
KR20060130216A (ko) 2006-12-18
NZ549870A (en) 2010-05-28
CN1942172A (zh) 2007-04-04
JO3102B1 (ar) 2017-09-20
AU2005224008B2 (en) 2010-09-16
PE20060716A1 (es) 2006-07-25
MXPA06010593A (es) 2007-02-16
AR049010A1 (es) 2006-06-21
ES2566618T3 (es) 2016-04-14
BRPI0508170A (pt) 2007-08-07
AU2005224008A1 (en) 2005-09-29
TNSN06277A1 (en) 2007-12-03
US8153104B2 (en) 2012-04-10
CA2560226A1 (fr) 2005-09-29
WO2005089717A1 (fr) 2005-09-29
RU2371171C2 (ru) 2009-10-27
NO342481B1 (no) 2018-05-28
HK1101346A1 (en) 2007-10-18
US20070202053A1 (en) 2007-08-30
MA28514B1 (fr) 2007-04-03
CN1942172B (zh) 2010-10-06
NO20064161L (no) 2006-10-17

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