ZA200610664B - Process for formulating fast dispersing dosage forms comprising at least one fish gelatin selected on the basis of molecular weight - Google Patents

Process for formulating fast dispersing dosage forms comprising at least one fish gelatin selected on the basis of molecular weight Download PDF

Info

Publication number: ZA200610664B
Authority: ZA; South Africa
Prior art keywords: molecular weight; gelatin; process according; oral; dosage form
Prior art date: 2004-06-03

Application number

ZA200610664A

Other languages

English (en)

Inventor

Wong Desmond Yik Teng

Grother Leon Paul

Brzozowski Andrzej Jan

Original Assignee

Scherer Technologies Inc R P

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-06-03

Filing date

2006-12-18

Publication date

2007-12-27

2006-12-18 Application filed by Scherer Technologies Inc R P filed Critical Scherer Technologies Inc R P

2007-12-27 Publication of ZA200610664B publication Critical patent/ZA200610664B/en

Links

108010010803 Gelatin Proteins 0.000 title claims description 107
229920000159 gelatin Polymers 0.000 title claims description 107
235000019322 gelatine Nutrition 0.000 title claims description 107
235000011852 gelatine desserts Nutrition 0.000 title claims description 107
239000008273 gelatin Substances 0.000 title claims description 101
238000000034 method Methods 0.000 title claims description 53
239000002552 dosage form Substances 0.000 title claims description 47
241000251468 Actinopterygii Species 0.000 title claims description 44
239000000203 mixture Substances 0.000 claims description 25
239000007787 solid Substances 0.000 claims description 24
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 23
239000004480 active ingredient Substances 0.000 claims description 21
239000002904 solvent Substances 0.000 claims description 20
239000013543 active substance Substances 0.000 claims description 17
239000003814 drug Substances 0.000 claims description 13
238000009826 distribution Methods 0.000 claims description 10
238000009472 formulation Methods 0.000 claims description 10
239000012530 fluid Substances 0.000 claims description 7
238000004108 freeze drying Methods 0.000 claims description 7
210000000214 mouth Anatomy 0.000 claims description 7
238000004519 manufacturing process Methods 0.000 claims description 4
239000008194 pharmaceutical composition Substances 0.000 claims description 4
238000007605 air drying Methods 0.000 claims description 3
239000003086 colorant Substances 0.000 claims description 2
239000013020 final formulation Substances 0.000 claims description 2
239000000796 flavoring agent Substances 0.000 claims description 2
235000013355 food flavoring agent Nutrition 0.000 claims description 2
239000000546 pharmaceutical excipient Substances 0.000 claims description 2
229940124597 therapeutic agent Drugs 0.000 claims description 2
238000010521 absorption reaction Methods 0.000 description 8
239000006185 dispersion Substances 0.000 description 6
229940079593 drug Drugs 0.000 description 6
239000007788 liquid Substances 0.000 description 5
239000006186 oral dosage form Substances 0.000 description 5
239000003795 chemical substances by application Substances 0.000 description 4
239000000499 gel Substances 0.000 description 4
239000002775 capsule Substances 0.000 description 3
230000002496 gastric effect Effects 0.000 description 3
239000000463 material Substances 0.000 description 3
239000011159 matrix material Substances 0.000 description 3
238000004806 packaging method and process Methods 0.000 description 3
239000006187 pill Substances 0.000 description 3
239000007909 solid dosage form Substances 0.000 description 3
238000000859 sublimation Methods 0.000 description 3
230000008022 sublimation Effects 0.000 description 3
230000000153 supplemental effect Effects 0.000 description 3
230000009747 swallowing Effects 0.000 description 3
239000003826 tablet Substances 0.000 description 3
238000012360 testing method Methods 0.000 description 3
239000012876 carrier material Substances 0.000 description 2
239000006260 foam Substances 0.000 description 2
238000012545 processing Methods 0.000 description 2
210000003296 saliva Anatomy 0.000 description 2
210000003491 skin Anatomy 0.000 description 2
239000000725 suspension Substances 0.000 description 2
230000007704 transition Effects 0.000 description 2
241000283690 Bos taurus Species 0.000 description 1
241001465754 Metazoa Species 0.000 description 1
208000027089 Parkinsonian disease Diseases 0.000 description 1
206010034010 Parkinsonism Diseases 0.000 description 1
235000017276 Salvia Nutrition 0.000 description 1
240000007164 Salvia officinalis Species 0.000 description 1
238000013459 approach Methods 0.000 description 1
238000010009 beating Methods 0.000 description 1
230000009286 beneficial effect Effects 0.000 description 1
210000001124 body fluid Anatomy 0.000 description 1
210000000988 bone and bone Anatomy 0.000 description 1
210000005178 buccal mucosa Anatomy 0.000 description 1
239000000084 colloidal system Substances 0.000 description 1
150000001875 compounds Chemical class 0.000 description 1
238000013461 design Methods 0.000 description 1
238000011161 development Methods 0.000 description 1
238000004090 dissolution Methods 0.000 description 1
230000000694 effects Effects 0.000 description 1
238000011067 equilibration Methods 0.000 description 1
238000010579 first pass effect Methods 0.000 description 1
235000013305 food Nutrition 0.000 description 1
-1 for example Substances 0.000 description 1
238000007710 freezing Methods 0.000 description 1
230000008014 freezing Effects 0.000 description 1
230000036571 hydration Effects 0.000 description 1
238000006703 hydration reaction Methods 0.000 description 1
230000007062 hydrolysis Effects 0.000 description 1
238000006460 hydrolysis reaction Methods 0.000 description 1
238000001727 in vivo Methods 0.000 description 1
210000003041 ligament Anatomy 0.000 description 1
210000004185 liver Anatomy 0.000 description 1
238000005259 measurement Methods 0.000 description 1
238000002483 medication Methods 0.000 description 1
230000000926 neurological effect Effects 0.000 description 1
239000003960 organic solvent Substances 0.000 description 1
230000008447 perception Effects 0.000 description 1
239000000825 pharmaceutical preparation Substances 0.000 description 1
230000000704 physical effect Effects 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
108090000623 proteins and genes Proteins 0.000 description 1
102000004169 proteins and genes Human genes 0.000 description 1
238000011160 research Methods 0.000 description 1
210000002784 stomach Anatomy 0.000 description 1
238000003860 storage Methods 0.000 description 1
239000000126 substance Substances 0.000 description 1
230000009885 systemic effect Effects 0.000 description 1
210000002435 tendon Anatomy 0.000 description 1
210000001519 tissue Anatomy 0.000 description 1
239000006208 topical dosage form Substances 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2063—Proteins, e.g. gelatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Biomedical Technology (AREA)
Gastroenterology & Hepatology (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Physiology (AREA)
Nutrition Science (AREA)
Emergency Medicine (AREA)
Botany (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

ZA200610664A 2004-06-03 2006-12-18 Process for formulating fast dispersing dosage forms comprising at least one fish gelatin selected on the basis of molecular weight ZA200610664B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US10/860,106 US7972621B2 (en)	2004-06-03	2004-06-03	Process for formulating fast dispersing dosage forms comprising at least one fish gelatin selected on the basis of molecular weight

Publications (1)

Publication Number	Publication Date
ZA200610664B true ZA200610664B (en)	2007-12-27

Family

ID=35449231

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200610664A ZA200610664B (en)	2004-06-03	2006-12-18	Process for formulating fast dispersing dosage forms comprising at least one fish gelatin selected on the basis of molecular weight

Country Status (19)

Country	Link
US (1)	US7972621B2 (pt)
EP (1)	EP1765299B1 (pt)
JP (1)	JP5144258B2 (pt)
KR (1)	KR101161430B1 (pt)
CN (2)	CN102172345B (pt)
AU (1)	AU2005251773B2 (pt)
BR (1)	BRPI0511067B8 (pt)
CA (1)	CA2567830C (pt)
DK (1)	DK1765299T3 (pt)
ES (1)	ES2654293T3 (pt)
HU (1)	HU230429B1 (pt)
IL (1)	IL179777A (pt)
IS (1)	IS8588A (pt)
MX (1)	MXPA06013921A (pt)
NO (1)	NO342135B1 (pt)
PL (2)	PL218958B1 (pt)
RU (1)	RU2415665C2 (pt)
WO (1)	WO2005120464A1 (pt)
ZA (1)	ZA200610664B (pt)

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* Cited by examiner, † Cited by third party
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GB9908014D0 (en) *	1999-04-08	1999-06-02	Scherer Corp R P	Pharmaceutical compositions
US20060210590A1 (en)	2005-02-03	2006-09-21	Alk-Abello A/S	Minor allergen control to increase safety of immunotherapy
AU2006248743B2 (en) *	2005-05-19	2012-02-02	Aqua Bio Technology Asa	Gelatin-containing topical composition
DE102006033168A1 (de) *	2006-07-10	2008-01-17	Gelita Ag	Verwendung von Gelatine und einem Vernetzungsmittel zur Herstellung einer vernetzenden therapeutischen Zusammensetzung
MX2010009493A (es) *	2008-02-28	2010-12-20	Rp Scherer Technologies Llc	Proceso para minimizar el polimorfismo.
US10548839B2 (en)	2010-03-16	2020-02-04	Wei Tian	Process of manufacturing a lyophilized fast dissolving, multi-phasic dosage form
AU2011312107B2 (en) *	2010-10-08	2016-06-23	R.P. Scherer Technologies, Llc	Oral vaccine fast-dissolving dosage form using starch
KR102793584B1 (ko)	2016-12-31	2025-04-09	바이오엑셀 테라퓨틱스 인코포레이티드	불안의 치료를 위한 설하 덱스메데토미딘의 용도
PL3813802T3 (pl)	2018-06-27	2025-04-22	Bioxcel Therapeutics, Inc.	Formulacje błony zawierające deksmedetomidynę i sposoby ich wytwarzania
US11523988B2 (en)	2018-11-29	2022-12-13	Catalent U.K. Swindon Zydis Limited	Oral dispersible vaccine comprising virosomes
EP3999058A4 (en)	2019-07-19	2023-05-03	Bioxcel Therapeutics, Inc.	NON-SEDATIVE DEXMEDETOMIDINE-BASED TREATMENT REGIMEN
US20240000705A1 (en) *	2020-09-17	2024-01-04	Catalent U.K. Swindon Zydis Limited	Use of surfactant with high molecular weight fish gelatin based dosage formulations to improve flow characteristics
WO2022074127A2 (en) *	2020-10-08	2022-04-14	Catalent U.K. Swindon Zydis Limited	Stable oral dispersible formulation for epinephrine and salts or solvates thereof
US11672761B2 (en)	2020-11-16	2023-06-13	Orcosa Inc.	Rapidly infusing platform and compositions for therapeutic treatment in humans
WO2022103638A1 (en)	2020-11-16	2022-05-19	Orcosa Inc.	Cannabinoids in the treatment of autism spectrum disorder
EP4351585A1 (en)	2021-06-11	2024-04-17	Orphai Therapeutics Inc.	Stabilized apilimod compositions and uses thereof
US11806334B1 (en)	2023-01-12	2023-11-07	Bioxcel Therapeutics, Inc.	Non-sedating dexmedetomidine treatment regimens

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GB1548022A (en)	1976-10-06	1979-07-04	Wyeth John & Brother Ltd	Pharmaceutial dosage forms
GB2111423B (en)	1981-12-02	1985-06-26	Wyeth John & Brother Ltd	Making quick-dissolving pills
US4760093A (en) *	1986-10-21	1988-07-26	American Home Products Corporation (Del.)	Spray dried acetaminophen
US4767789A (en) *	1986-10-21	1988-08-30	American Home Products Corporation (Del.)	Spray dried acetaminophen
US4760094A (en) *	1986-10-21	1988-07-26	American Home Products Corporation (Del.)	Spray dried acetaminophen
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US5215756A (en) *	1989-12-22	1993-06-01	Gole Dilip J	Preparation of pharmaceutical and other matrix systems by solid-state dissolution
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IL105553A (en) *	1992-05-06	1998-01-04	Janssen Pharmaceutica Inc	Solid dosage form comprising a porous network of matrix forming material which disperses rapidly in water
EP0622413B1 (en)	1992-11-11	2002-02-27	Toray Industries, Inc.	Polyester films for magnetic recording media
US6726928B2 (en) *	1994-10-28	2004-04-27	R.P. Scherer Technologies, Inc.	Process for preparing solid dosage forms for unpalatable pharmaceuticals
GB9517062D0 (en) *	1995-08-18	1995-10-25	Scherer Ltd R P	Pharmaceutical compositions
EP0910339B1 (en) *	1996-04-12	2005-02-02	Novadel Pharma Inc.	Buccal polar spray
US6258380B1 (en) *	1999-03-05	2001-07-10	Banner Pharmacaps, Inc.	Chewable soft capsule
GB9908014D0 (en)	1999-04-08	1999-06-02	Scherer Corp R P	Pharmaceutical compositions
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US6709699B2 (en) *	2000-09-27	2004-03-23	Kabushiki Kaisha Toshiba	Film-forming method, film-forming apparatus and liquid film drying apparatus
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GB0210397D0 (en) *	2002-05-07	2002-06-12	Ferring Bv	Pharmaceutical formulations
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GB2388776B (en) *	2002-05-21	2004-08-25	Croda Int Plc	Succinylated fish gelatin for use as a blood plasma expander
GB0226076D0 (en)	2002-11-08	2002-12-18	Rp Scherer Technologies Inc	Improved formulations containing substituted imidazole derivatives

2004
- 2004-06-03 US US10/860,106 patent/US7972621B2/en active Active
2005
- 2005-06-03 EP EP05758824.6A patent/EP1765299B1/en not_active Expired - Lifetime
- 2005-06-03 CN CN201110058244.1A patent/CN102172345B/zh not_active Expired - Lifetime
- 2005-06-03 CA CA2567830A patent/CA2567830C/en not_active Expired - Lifetime
- 2005-06-03 ES ES05758824.6T patent/ES2654293T3/es not_active Expired - Lifetime
- 2005-06-03 RU RU2006147244/15A patent/RU2415665C2/ru active
- 2005-06-03 KR KR1020077000078A patent/KR101161430B1/ko not_active Expired - Lifetime
- 2005-06-03 MX MXPA06013921A patent/MXPA06013921A/es active IP Right Grant
- 2005-06-03 CN CNA2005800178323A patent/CN1960710A/zh active Pending
- 2005-06-03 AU AU2005251773A patent/AU2005251773B2/en not_active Expired
- 2005-06-03 WO PCT/US2005/019589 patent/WO2005120464A1/en not_active Ceased
- 2005-06-03 HU HU0700043A patent/HU230429B1/hu unknown
- 2005-06-03 JP JP2007515624A patent/JP5144258B2/ja not_active Expired - Lifetime
- 2005-06-03 DK DK05758824.6T patent/DK1765299T3/en active
- 2005-06-03 PL PL382307A patent/PL218958B1/pl unknown
- 2005-06-03 BR BRPI0511067A patent/BRPI0511067B8/pt not_active IP Right Cessation
- 2005-06-03 PL PL05758824T patent/PL1765299T3/pl unknown
2006
- 2006-11-30 IL IL179777A patent/IL179777A/en active IP Right Grant
- 2006-12-18 ZA ZA200610664A patent/ZA200610664B/en unknown
- 2006-12-28 IS IS8588A patent/IS8588A/is unknown
- 2006-12-29 NO NO20066070A patent/NO342135B1/no unknown

Also Published As

Publication number	Publication date
DK1765299T3 (en)	2018-01-22
RU2415665C2 (ru)	2011-04-10
CN102172345A (zh)	2011-09-07
PL1765299T3 (pl)	2018-05-30
ES2654293T3 (es)	2018-02-13
HU230429B1 (hu)	2016-06-28
JP2008501709A (ja)	2008-01-24
AU2005251773A1 (en)	2005-12-22
JP5144258B2 (ja)	2013-02-13
BRPI0511067B8 (pt)	2021-05-25
IL179777A0 (en)	2007-05-15
PL218958B1 (pl)	2015-02-27
HUP0700043A2 (en)	2009-03-02
IL179777A (en)	2015-09-24
WO2005120464A1 (en)	2005-12-22
BRPI0511067A (pt)	2007-12-26
CA2567830C (en)	2013-08-13
HUP0700043A3 (en)	2012-09-28
AU2005251773B2 (en)	2010-12-16
CN1960710A (zh)	2007-05-09
CA2567830A1 (en)	2005-12-22
EP1765299A1 (en)	2007-03-28
KR101161430B1 (ko)	2012-07-02
PL382307A1 (pl)	2007-08-20
NO342135B1 (no)	2018-03-26
RU2006147244A (ru)	2008-07-20
EP1765299A4 (en)	2011-03-09
US20050271719A1 (en)	2005-12-08
US7972621B2 (en)	2011-07-05
CN102172345B (zh)	2018-05-04
NO20066070L (no)	2007-02-27
KR20070039524A (ko)	2007-04-12
MXPA06013921A (es)	2007-01-26
IS8588A (is)	2006-12-28
BRPI0511067B1 (pt)	2018-11-06
EP1765299B1 (en)	2017-11-15

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