ZA200704254B - LNA oligonucleotides and the treatment of cancer - Google Patents

LNA oligonucleotides and the treatment of cancer

Info

Publication number: ZA200704254B
Authority: ZA; South Africa
Prior art keywords: cancer; treatment; lna oligonucleotides; lna; oligonucleotides
Prior art date: 2004-11-09

Application number

ZA200704254A

Other languages

English (en)

Inventor

Kjaerulff Lene Soenderbye

Asklund Marlene

Westergaard Majken

Rosenbohm Christoph

Wissenbach Margit

Hansen Bo

Original Assignee

Santaris Pharma As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-11-09

Filing date

2005-11-09

Publication date

2009-09-30

2005-11-09 Application filed by Santaris Pharma As filed Critical Santaris Pharma As

2009-09-30 Publication of ZA200704254B publication Critical patent/ZA200704254B/xx

Links

206010028980 Neoplasm Diseases 0.000 title 1
108091034117 Oligonucleotide Proteins 0.000 title 1
JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 title 1
201000011510 cancer Diseases 0.000 title 1

ZA200704254A 2004-11-09 2005-11-09 LNA oligonucleotides and the treatment of cancer ZA200704254B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DKPA200401728		2004-11-09

Publications (1)

Publication Number	Publication Date
ZA200704254B true ZA200704254B (en)	2009-09-30

Family

ID=38965697

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200704254A ZA200704254B (en)	2004-11-09	2005-11-09	LNA oligonucleotides and the treatment of cancer

Country Status (6)

Country	Link
CN (1)	CN101065485B (de)
AT (1)	ATE482271T1 (de)
DE (1)	DE602005023772D1 (de)
DK (1)	DK1824975T3 (de)
ES (1)	ES2353638T3 (de)
ZA (1)	ZA200704254B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN102361985B (zh) *	2008-12-04	2017-06-20	库尔纳公司	通过抑制肿瘤抑制基因的天然反义转录物治疗肿瘤抑制基因相关性疾病

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1178999B1 (de) *	1999-05-04	2007-03-14	Santaris Pharma A/S	L-ribo-lna analoge
WO2003091384A2 (en) *	2002-04-24	2003-11-06	Eirx Therapeutics Limited	A role for survivin in apoptosis of myeloid cells
PT1592793E (pt) *	2003-02-10	2009-09-30	Santaris Pharma As	Compostos oligoméricos para a modulação da expressão de survivina

2005
- 2005-11-09 ZA ZA200704254A patent/ZA200704254B/xx unknown
- 2005-11-09 AT AT05800759T patent/ATE482271T1/de not_active IP Right Cessation
- 2005-11-09 ES ES05800759T patent/ES2353638T3/es not_active Expired - Lifetime
- 2005-11-09 DE DE602005023772T patent/DE602005023772D1/de not_active Expired - Lifetime
- 2005-11-09 DK DK05800759.2T patent/DK1824975T3/da active
- 2005-11-09 CN CN2005800409084A patent/CN101065485B/zh not_active Expired - Fee Related

Also Published As

Publication number	Publication date
ES2353638T9 (es)	2011-06-16
ES2353638T3 (es)	2011-03-03
CN101065485B (zh)	2011-12-07
CN101065485A (zh)	2007-10-31
ATE482271T1 (de)	2010-10-15
DK1824975T3 (da)	2011-06-06
DE602005023772D1 (de)	2010-11-04

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