ZA200706692B - Orally disintegrating composition of olanzapine of donepezil - Google Patents

Orally disintegrating composition of olanzapine of donepezil Download PDF

Info

Publication number: ZA200706692B
Authority: ZA; South Africa
Prior art keywords: composition according; weight; donepezil; tablets; olanzapine
Prior art date: 2005-01-14

Application number

ZA200706692A

Other languages

English (en)

Inventor

Kroselj Vesna

Kolaric Sasa

Jakse Renata

Vrbinc Miha

Original Assignee

Krka Tovarna Zdravil D D Novo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-01-14

Filing date

2007-08-13

Publication date

2008-07-30

2007-08-13 Application filed by Krka Tovarna Zdravil D D Novo filed Critical Krka Tovarna Zdravil D D Novo

2008-07-30 Publication of ZA200706692B publication Critical patent/ZA200706692B/en

Links

239000000203 mixture Substances 0.000 title claims abstract description 75
ADEBPBSSDYVVLD-UHFFFAOYSA-N donepezil Chemical compound O=C1C=2C=C(OC)C(OC)=CC=2CC1CC(CC1)CCN1CC1=CC=CC=C1 ADEBPBSSDYVVLD-UHFFFAOYSA-N 0.000 title claims abstract description 48
KVWDHTXUZHCGIO-UHFFFAOYSA-N olanzapine Chemical compound C1CN(C)CCN1C1=NC2=CC=CC=C2NC2=C1C=C(C)S2 KVWDHTXUZHCGIO-UHFFFAOYSA-N 0.000 title claims abstract description 30
229960005017 olanzapine Drugs 0.000 title claims abstract description 29
229960003530 donepezil Drugs 0.000 title claims abstract description 24
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OYACROKNLOSFPA-UHFFFAOYSA-N calcium;dioxido(oxo)silane Chemical compound [Ca+2].[O-][Si]([O-])=O OYACROKNLOSFPA-UHFFFAOYSA-N 0.000 claims description 29
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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Inorganic Chemistry (AREA)
Zoology (AREA)
Nutrition Science (AREA)
Physiology (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Hydrogenated Pyridines (AREA)

ZA200706692A 2005-01-14 2007-08-13 Orally disintegrating composition of olanzapine of donepezil ZA200706692B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP05000664A EP1681048A1 (de)	2005-01-14	2005-01-14	Im Munde zerfallende Zusammensetzungen mit Olanzapin oder Donepezil

Publications (1)

Publication Number	Publication Date
ZA200706692B true ZA200706692B (en)	2008-07-30

Family

ID=34933289

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200706692A ZA200706692B (en)	2005-01-14	2007-08-13	Orally disintegrating composition of olanzapine of donepezil

Country Status (15)

Country	Link
EP (2)	EP1681048A1 (de)
AT (1)	ATE465719T1 (de)
AU (1)	AU2006205817A1 (de)
DE (1)	DE602006013940D1 (de)
DK (1)	DK1845954T3 (de)
EA (1)	EA013742B1 (de)
ES (1)	ES2344959T3 (de)
HR (1)	HRP20100399T1 (de)
NO (1)	NO20074087L (de)
PL (1)	PL1845954T3 (de)
PT (1)	PT1845954E (de)
SI (1)	SI1845954T1 (de)
UA (1)	UA89394C2 (de)
WO (1)	WO2006074951A2 (de)
ZA (1)	ZA200706692B (de)

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US7879382B2 (en)	2005-09-30	2011-02-01	Fmc Corporation	Stabilizers and compositions and products comprising same
DE102005060377A1 (de) *	2005-12-16	2007-06-21	Ratiopharm Gmbh	Pharmazeutische Zusammensetzung enthaltend Donepezilhydrochlorid, Tablette hieraus und Verfahren zu deren Herstellung
JP5535616B2 (ja) *	2006-03-31	2014-07-02	ルビコンリサーチプライベートリミテッド	口腔内崩壊錠剤のための直接圧縮性複合材
GB0614586D0 (en) *	2006-07-22	2006-08-30	Pliva Istrazivacki Inst D O O	Pharmaceutical Formulation
AU2007304425B2 (en)	2006-10-02	2013-12-05	Spepharma Ag	Non-mucoadhesive film dosage forms
EP2076249A2 (de) *	2006-10-27	2009-07-08	FMC Corporation	Trockene granulationsbindemittel, produkte und ihre verwendung
BRPI0808889A2 (pt)	2007-03-13	2014-11-11	Dainippon Sumitomo Pharma Co	Comprimido desintegrante oral
PT2572705T (pt)	2007-10-01	2017-11-08	Lesvi Laboratorios Sl	Comprimidos orodispersíveis
CN101756917A (zh) *	2008-10-24	2010-06-30	北京科信必成医药科技发展有限公司	盐酸多奈哌齐口腔崩解片及其制备方法
WO2010070611A1 (en) *	2008-12-18	2010-06-24	Ranbaxy Laboratories Limited	Atazanavir formulations
EP2198857A1 (de)	2008-12-19	2010-06-23	Ratiopharm GmbH	Orale dispergierbare Tablette
TR200903293A1 (tr) *	2009-04-28	2010-11-22	Sanovel İlaç San. Ve Ti̇c. A.Ş.	Oral yolla dağılan olanzapin tablet.
TR201002084A1 (tr) *	2010-03-19	2011-10-21	Sanovel İlaç Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇	Oral yolla dağılan donepezil tablet formülasyonları ve hazırlama yöntemi
FR2962331B1 (fr) *	2010-07-06	2020-04-24	Ethypharm	Forme pharmaceutique pour lutter contre la soumission chimique, methode la mettant en oeuvre
WO2012014012A1 (es) *	2010-07-27	2012-02-02	Laboratorios Andrómaco S.A.	Procedimiento para preparar comprimidos de disolucion rapida oral que comprenden la forma i de olanzapina, los comprimidos obtenidos y su uso para el tratamiento de la esquizofrenia.
JP6188030B2 (ja)	2011-10-05	2017-08-30	エフエムシーコーポレーションＦｍｃＣｏｒｐｏｒａｔｉｏｎ	微結晶セルロースおよびカルボキシメチルセルロースの安定化剤組成物、該組成物の製造方法並びに食品製品
CN103857739B (zh)	2011-10-05	2017-04-19	Fmc有限公司	共磨碎微晶纤维素和羧甲基纤维素的稳定剂组合物、制备方法和应用
CN104010522A (zh)	2011-12-09	2014-08-27	Fmc有限公司	共磨碎稳定剂组合物
US20150216798A1 (en) *	2012-08-17	2015-08-06	Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi	Novel orally administered pharmaceutical formulations
FR2999432B1 (fr) *	2012-12-17	2014-12-12	Ethypharm Sa	Comprimes orodispersibles obtenus par compression moulage
CN104510717B (zh) *	2013-09-27	2019-02-05	江苏豪森药业集团有限公司	奥氮平口崩片及其制备方法
CN108261399A (zh) *	2016-12-30	2018-07-10	江苏豪森药业集团有限公司	奥氮平口腔崩解片及其制备方法
CN108926543A (zh) *	2017-05-26	2018-12-04	万全万特制药江苏有限公司	一种奥氮平口腔崩解片及其制备方法
CN109498544A (zh) *	2017-09-15	2019-03-22	万全万特制药江苏有限公司	稳定的奥氮平组合物及其制备方法

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EP1260215B1 (de) *	2000-03-01	2009-07-29	Eisai R&D Management Co., Ltd.	Schnellzerfallende polyvinylhaltige tablette
WO2003086361A1 (en) *	2002-04-18	2003-10-23	Dr. Reddy's Laboratories Ltd.	Rapidly dispersing solid oral compositions

2005
- 2005-01-14 EP EP05000664A patent/EP1681048A1/de not_active Withdrawn
2006
- 2006-01-13 DK DK06701464.7T patent/DK1845954T3/da active
- 2006-01-13 PL PL06701464T patent/PL1845954T3/pl unknown
- 2006-01-13 EP EP06701464A patent/EP1845954B1/de not_active Expired - Lifetime
- 2006-01-13 PT PT06701464T patent/PT1845954E/pt unknown
- 2006-01-13 SI SI200630726T patent/SI1845954T1/sl unknown
- 2006-01-13 AT AT06701464T patent/ATE465719T1/de active
- 2006-01-13 WO PCT/EP2006/000284 patent/WO2006074951A2/en not_active Ceased
- 2006-01-13 DE DE602006013940T patent/DE602006013940D1/de not_active Expired - Lifetime
- 2006-01-13 ES ES06701464T patent/ES2344959T3/es not_active Expired - Lifetime
- 2006-01-13 HR HR20100399T patent/HRP20100399T1/hr unknown
- 2006-01-13 EA EA200701462A patent/EA013742B1/ru not_active IP Right Cessation
- 2006-01-13 AU AU2006205817A patent/AU2006205817A1/en not_active Abandoned
- 2006-01-13 UA UAA200709252A patent/UA89394C2/uk unknown
2007
- 2007-08-07 NO NO20074087A patent/NO20074087L/no not_active Application Discontinuation
- 2007-08-13 ZA ZA200706692A patent/ZA200706692B/en unknown

Also Published As

Publication number	Publication date
AU2006205817A1 (en)	2006-07-20
PT1845954E (pt)	2010-08-02
WO2006074951A2 (en)	2006-07-20
WO2006074951A3 (en)	2007-04-26
DE602006013940D1 (de)	2010-06-10
SI1845954T1 (sl)	2010-08-31
ES2344959T3 (es)	2010-09-10
PL1845954T3 (pl)	2010-10-29
NO20074087L (no)	2007-10-09
DK1845954T3 (da)	2010-08-16
EP1681048A1 (de)	2006-07-19
EA200701462A1 (ru)	2008-02-28
UA89394C2 (uk)	2010-01-25
EP1845954A2 (de)	2007-10-24
ATE465719T1 (de)	2010-05-15
EP1845954B1 (de)	2010-04-28
HRP20100399T1 (hr)	2010-09-30
EA013742B1 (ru)	2010-06-30

Publication	Publication Date	Title
EP1845954B1 (de)	2010-04-28	Oral zerfallende zusammensetzung von olanzapin oder donepezil
EP3024442B1 (de)	2019-01-16	Zusammensetzungen mit amorphem dapagliflozin
EP2842549B1 (de)	2018-08-08	Im mund zerfallende tablette und verfahren zur herstellung davon
EP2988733B1 (de)	2019-03-27	Pharmazeutische zusammensetzungen mit kristallinem macitentan
WO2008104996A2 (en)	2008-09-04	Water dispersible pharmaceutical formulation and process for preparing the same
EP1260215A1 (de)	2002-11-27	Schnellzerfallende polyvinylhaltige tablette
NZ582690A (en)	2011-12-22	A composition comprising lercanidipine and an amount of a colloidal silicon dioxide from 5% to 25% by weight to enhance bioavailabilty and/or solubility
US20120276199A1 (en)	2012-11-01	Taste masked pharmaceutical formulations
KR20140030212A (ko)	2014-03-11	구강내 속붕괴성정
JP2011526612A (ja)	2011-10-13	口腔内崩壊性マンニトール
ES2596324T3 (es)	2017-01-05	Preparación de teneligliptina con elución estabilizada
WO2010041277A2 (en)	2010-04-15	Stable pharmaceutical compositions of montelukast or its salts or solvates or hydrates
JP4446177B2 (ja)	2010-04-07	耐湿性口腔内崩壊錠の製造方法
KR20150003726A (ko)	2015-01-09	프라수그렐을 함유하는 안정한 즉시방출형 경구 약제학적 조성물
JP2019019125A (ja)	2019-02-07	口腔内崩壊錠及びその製造方法
JP5572321B2 (ja)	2014-08-13	被覆微粒子含有口腔内崩壊錠
Amrutkar et al.	2010	Design and evaluation of taste masked chewable dispersible tablet of lamotrigine by melt granulation
WO2006008512A2 (en)	2006-01-26	Anti-histaminic composition
JP7650274B2 (ja)	2025-03-24	ゾニサミド口腔分散性錠剤
AU2012241189A1 (en)	2014-04-24	Fast Dissolving Solid Dosage Form
US20100179202A1 (en)	2010-07-15	Orally disintegrating composition of zolmitriptan
JP5226732B2 (ja)	2013-07-03	催眠用圧縮成型製剤
WO2010100658A2 (en)	2010-09-10	Stable olanzapine tablets and the process for its preparation
KR20250042819A (ko)	2025-03-27	드로타베린의 맛좋은 경구 붕해성 제형 및 이의 제조 방법
HK1087948B (en)	2007-05-18	Fast water-dispersible domperidone tablets