ZA200905447B - Multivariable antigens complexed with targeting humanized monoclonal antibody - Google Patents
Multivariable antigens complexed with targeting humanized monoclonal antibodyInfo
- Publication number
- ZA200905447B ZA200905447B ZA200905447A ZA200905447A ZA200905447B ZA 200905447 B ZA200905447 B ZA 200905447B ZA 200905447 A ZA200905447 A ZA 200905447A ZA 200905447 A ZA200905447 A ZA 200905447A ZA 200905447 B ZA200905447 B ZA 200905447B
- Authority
- ZA
- South Africa
- Prior art keywords
- monoclonal antibody
- humanized monoclonal
- antigens complexed
- targeting humanized
- multivariable
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/44—Antibodies bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/35—Valency
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/54—F(ab')2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Transplantation (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US88802907P | 2007-02-02 | 2007-02-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200905447B true ZA200905447B (en) | 2010-05-26 |
Family
ID=39682338
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200905447A ZA200905447B (en) | 2007-02-02 | 2009-08-04 | Multivariable antigens complexed with targeting humanized monoclonal antibody |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US7786267B2 (fr) |
| EP (2) | EP2114985B1 (fr) |
| JP (1) | JP5543785B2 (fr) |
| KR (1) | KR20090114425A (fr) |
| CN (1) | CN101657464A (fr) |
| AU (1) | AU2008214077B2 (fr) |
| BR (1) | BRPI0807344A2 (fr) |
| CA (1) | CA2715042C (fr) |
| DK (1) | DK2114985T3 (fr) |
| ES (1) | ES2536900T3 (fr) |
| IL (1) | IL200092A0 (fr) |
| MX (1) | MX2009008143A (fr) |
| NZ (2) | NZ578657A (fr) |
| TW (1) | TW200846371A (fr) |
| WO (1) | WO2008097817A2 (fr) |
| ZA (1) | ZA200905447B (fr) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ578657A (en) * | 2007-02-02 | 2012-02-24 | Baylor Res Inst | Multivariable antigens complexed with targeting humanized monoclonal antibody |
| TWI422594B (zh) | 2007-02-02 | 2014-01-11 | Baylor Res Inst | 經由樹狀細胞去唾液酸糖蛋白受體(dc-asgpr)接合抗原呈現細胞之藥劑 |
| MX2009008140A (es) | 2007-02-02 | 2009-10-26 | Baylor Res Inst | Vacunas a base de antigeno dirigido a dcir expresado en celulas que presentan antigeno. |
| CN101679949B (zh) * | 2007-02-23 | 2015-08-19 | 贝勒研究院 | 通过dectin-1激活人抗原呈递细胞的治疗性应用 |
| CA2717656A1 (fr) * | 2007-02-23 | 2008-08-28 | Baylor Research Institute | Activation de cellules humaines presentant un antigene par l'intermediaire de clec-6 |
| US8574577B2 (en) | 2008-01-03 | 2013-11-05 | The Scripps Research Institute | VEGF antibodies comprising modular recognition domains |
| US8557243B2 (en) | 2008-01-03 | 2013-10-15 | The Scripps Research Institute | EFGR antibodies comprising modular recognition domains |
| US8454960B2 (en) | 2008-01-03 | 2013-06-04 | The Scripps Research Institute | Multispecific antibody targeting and multivalency through modular recognition domains |
| KR101658247B1 (ko) | 2008-01-03 | 2016-09-22 | 더 스크립스 리서치 인스티튜트 | 모듈 인식 도메인을 통한 항체 표적화 |
| US8557242B2 (en) | 2008-01-03 | 2013-10-15 | The Scripps Research Institute | ERBB2 antibodies comprising modular recognition domains |
| US8518410B2 (en) * | 2009-03-10 | 2013-08-27 | Baylor Research Institute | Fusion protein with HIV antigen |
| US20110151538A1 (en) * | 2008-08-07 | 2011-06-23 | Ramot At Tel-Aviv University Ltd. | Affinity purification by cohesin-dockerin interaction |
| AU2010222942B2 (en) | 2009-03-10 | 2013-01-10 | Baylor Research Institute | Anti-CD40 antibodies and uses thereof |
| EP2406288B1 (fr) | 2009-03-10 | 2016-12-14 | Baylor Research Institute | Vaccins ciblés vers des cellules présentant des antigènes |
| WO2011071574A2 (fr) * | 2009-09-02 | 2011-06-16 | United States Deparment Of The Army, As Represented By The Secretary Of The Army | Anticorps monoclonaux dirigés contre la glycoprotéine du virus ebola souche soudan boniface |
| AU2010291939B2 (en) * | 2009-09-14 | 2012-11-15 | Baylor Research Institute | Vaccines directed to Langerhans cells |
| MX2012012833A (es) * | 2010-05-07 | 2012-11-30 | Baylor Res Inst | Cebado cruzado de celulas t cd8 positivas humanos moderada por inmunoreceptores de celulas dendriticas (dcir). |
| WO2012009705A1 (fr) | 2010-07-15 | 2012-01-19 | Zyngenia, Inc. | Complexes liant ang-2 et leurs utilisations |
| US9850296B2 (en) | 2010-08-10 | 2017-12-26 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| US9517257B2 (en) | 2010-08-10 | 2016-12-13 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| JP6017422B2 (ja) | 2010-08-10 | 2016-11-02 | エコール・ポリテクニーク・フェデラル・ドゥ・ローザンヌ(ウペエフエル)Ecole Polytechnique Federale de Lausanne (EPFL) | 赤血球結合療法 |
| US20120128710A1 (en) * | 2010-11-02 | 2012-05-24 | Baylor Research Institute | Enhancement of Pathogen-Specific Memory Th17 Cell Responses |
| US9078878B2 (en) | 2010-12-01 | 2015-07-14 | Alderbio Holdings Llc | Anti-NGF antibodies that selectively inhibit the association of NGF with TrkA, without affecting the association of NGF with p75 |
| US11214610B2 (en) | 2010-12-01 | 2022-01-04 | H. Lundbeck A/S | High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris |
| US9884909B2 (en) | 2010-12-01 | 2018-02-06 | Alderbio Holdings Llc | Anti-NGF compositions and use thereof |
| NZ611076A (en) | 2010-12-01 | 2015-09-25 | Alderbio Holdings Llc | Anti-ngf compositions and use thereof |
| US9539324B2 (en) | 2010-12-01 | 2017-01-10 | Alderbio Holdings, Llc | Methods of preventing inflammation and treating pain using anti-NGF compositions |
| US9067988B2 (en) | 2010-12-01 | 2015-06-30 | Alderbio Holdings Llc | Methods of preventing or treating pain using anti-NGF antibodies |
| US9623117B2 (en) * | 2011-04-04 | 2017-04-18 | Wisconsin Alumni Research Foundation | Method for selective targeting and entry of bacterial toxins to cells |
| EP2714738B1 (fr) | 2011-05-24 | 2018-10-10 | Zyngenia, Inc. | Complexes plurispécifiques multivalents et monovalents, et leurs utilisations |
| CN102850458B (zh) * | 2011-06-28 | 2014-10-01 | 华博生物医药技术(上海)有限公司 | 新型重组双功能融合蛋白及其制法和用途 |
| AR088428A1 (es) * | 2011-08-25 | 2014-06-11 | Baylor Res Inst | Ensayo multiplexado basado en esferas autoensambladas para anticuerpos especificos de antigenos |
| WO2013033104A1 (fr) * | 2011-08-29 | 2013-03-07 | Baylor Research Institute | Contrôle de l'allergie et de l'asthme par l'activation de cellules dendritiques humaines par le biais de la dectine-1 ou de la dectine-1 et du récepteur 2 de type toll (tlr2) |
| BR112014012460B1 (pt) * | 2011-11-23 | 2021-01-12 | Bioven 3 Limited | proteínas recombinantes |
| JP6629069B2 (ja) * | 2012-06-06 | 2020-01-15 | ゾエティス・エルエルシー | イヌ化抗ngf抗体およびその方法 |
| WO2014031984A1 (fr) * | 2012-08-24 | 2014-02-27 | Baylor Research Institute | Procédés de détection immunologique et compositions |
| CN103044552B (zh) * | 2012-12-11 | 2019-01-29 | 中国医学科学院病原生物学研究所 | 人源化的抗树突状细胞表面dec-205分子的单克隆抗体 |
| MX2015013163A (es) | 2013-03-15 | 2016-04-04 | Zyngenia Inc | Complejos multiespecificos multivalente y monovalentes y sus usos. |
| CA2916694C (fr) | 2013-06-28 | 2023-01-17 | Baylor Research Institute | Immunotherapie par ciblage d'asgpr de cellules dendritiques pour la sclerose en plaques |
| CN103409451A (zh) * | 2013-06-28 | 2013-11-27 | 扬州维克斯生物科技有限公司 | 一种向树突状细胞dc靶向加载肿瘤抗原肽的方法 |
| EP3094652B1 (fr) | 2014-01-13 | 2021-09-29 | Baylor Research Institute | Nouveaux vaccins contre le vph et maladies liées au vph |
| IL285403B2 (en) | 2014-01-27 | 2023-10-01 | Molecular Templates Inc | Polypeptides that remove an epitope for MHC group I |
| US10953101B2 (en) | 2014-02-21 | 2021-03-23 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
| US10946079B2 (en) | 2014-02-21 | 2021-03-16 | Ecole Polytechnique Federale De Lausanne | Glycotargeting therapeutics |
| KR20240154672A (ko) | 2014-02-21 | 2024-10-25 | 에꼴 뽈리떼끄닉 뻬데랄 드 로잔느 (으뻬에프엘) | 글리코타겟팅 치료제 |
| US10046056B2 (en) | 2014-02-21 | 2018-08-14 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
| JP6836500B2 (ja) | 2014-05-16 | 2021-03-03 | ベイラー リサーチ インスティテュートBaylor Research Institute | 自己免疫状態および炎症状態を治療するための方法および組成物 |
| KR20170110601A (ko) * | 2015-02-05 | 2017-10-11 | 몰레큘러 템플레이츠, 인코퍼레이션. | 시가 독소 a 서브유닛 작동체 영역을 포함하는 다가 cd20 결합 분자 및 이들의 강화된 조성물 |
| JP7075134B2 (ja) | 2016-12-07 | 2022-05-25 | モレキュラー テンプレーツ,インク. | 部位特異的コンジュゲーションのための志賀毒素aサブユニットエフェクターポリペプチド、志賀毒素エフェクター足場、及び細胞標的化分子 |
| EP3638296A1 (fr) | 2017-06-16 | 2020-04-22 | The University Of Chicago | Compositions et procédés d'induction d'une tolérance immunitaire |
| EP3424538A1 (fr) | 2017-07-06 | 2019-01-09 | Centre National De La Recherche Scientifique | Bioconjugués ayant un degré contrôlé de conjugaison, leur procédé de préparation et réactifs pour leur préparation |
| US10610585B2 (en) | 2017-09-26 | 2020-04-07 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods and compositions for treating and preventing HIV |
| SG11202011078VA (en) | 2018-05-09 | 2020-12-30 | Univ Chicago | Compositions and methods concerning immune tolerance |
| US20230053449A1 (en) | 2018-10-31 | 2023-02-23 | Novartis Ag | Dc-sign antibody drug conjugates |
| IL263409B2 (en) | 2018-12-02 | 2023-06-01 | Linet Spol Sro | Detection of tiny movement in the human body |
| EP3947454A1 (fr) | 2019-03-27 | 2022-02-09 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Protéines recombinantes ayant des propriétés d'activation de cd40 |
| CN110790836A (zh) * | 2019-11-22 | 2020-02-14 | 郑州安图生物工程股份有限公司 | 一种人抑制素b的单克隆抗体及其应用和试剂盒 |
| US20230183366A1 (en) | 2020-05-13 | 2023-06-15 | Inserm (Institut National De La Santé Et De La Recherch Médicale) | Recombinant proteins with ox40 activating properties |
| JP7858550B2 (ja) | 2020-05-26 | 2026-05-14 | アンスティチュート、ナシオナル、ドゥ、ラ、サンテ、エ、ドゥ、ラ、ルシェルシュ、メディカル | 重症急性呼吸器症候群コロナウイルス2(sars-cov-2)ポリペプチドおよびワクチン目的でのその使用 |
| KR20230107260A (ko) | 2020-11-12 | 2023-07-14 | 인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔) | Sars-cov-2 스파이크 단백질의 수용체-결합 도메인에 접합되거나 융합된 항체, 및 백신 목적을 위한 이의 용도 |
| US20240131138A1 (en) | 2020-12-23 | 2024-04-25 | Institut National De La Santé Et De La Recherche Médicale (Inserm) | Chlamydia vaccine based on targeting momp vs4 antigen to antigen presenting cells |
| EP4284832A1 (fr) | 2021-01-29 | 2023-12-06 | (INSERM) Institut National de la Santé et de la Recherche Médicale | Polypeptides antigéniques de chlamydia trachomatis et leurs utilisations à des fins vaccinales |
| EP4433504A1 (fr) | 2021-11-17 | 2024-09-25 | Institut National de la Santé et de la Recherche Médicale | Vaccins universels contre les sarbecovirus |
| EP4598953A1 (fr) | 2022-10-05 | 2025-08-13 | Institut National de la Santé et de la Recherche Médicale | Vaccin ciblant dc dirigé contre une infection par le virus nipah |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL154600B (nl) | 1971-02-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen. |
| US3949064A (en) | 1973-10-26 | 1976-04-06 | Baxter Laboratories, Inc. | Method of detecting antigens or antibodies |
| US4174384A (en) | 1975-06-30 | 1979-11-13 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4554101A (en) | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
| US20040258688A1 (en) * | 1995-01-31 | 2004-12-23 | Daniel Hawiger | Enhanced antigen delivery and modulation of the immune response therefrom |
| AU726108B2 (en) * | 1995-10-17 | 2000-11-02 | Genencor International, Inc. | Enzymatic array and process of making same |
| FR2748479A1 (fr) * | 1996-05-10 | 1997-11-14 | Pasteur Institut | Polypeptide comportant un nouveau domaine cohesine de type ii, composition enzymatique en comportant et fragments d'adn codant pour ces polypeptides |
| US6541011B2 (en) | 1998-02-11 | 2003-04-01 | Maxygen, Inc. | Antigen library immunization |
| JP2000157282A (ja) * | 1998-11-30 | 2000-06-13 | Toyota Central Res & Dev Lab Inc | 酵素配列複合体及び固定化酵素配列複合体とそれらの製造方法、担体分子及び酵素 |
| CA2365981A1 (fr) | 1999-03-24 | 2000-09-28 | Board Of Regents, The University Of Texas System | Elements d'expression lineaires et circulaires |
| EP1046651A1 (fr) * | 1999-04-19 | 2000-10-25 | Koninklijke Universiteit Nijmegen | Composition et méthode pour moduler l'interaction des cellules dendritiques et les cellules T |
| US7560534B2 (en) * | 2000-05-08 | 2009-07-14 | Celldex Research Corporation | Molecular conjugates comprising human monoclonal antibodies to dendritic cells |
| IL152747A0 (en) * | 2000-05-11 | 2003-06-24 | Altarex Inc | Therapeutic method and composition utilizing antigen-antibody complexation and presentation by dendritic cells |
| AU2002332598A1 (en) * | 2001-08-22 | 2003-03-10 | Shengfeng Li | Compositions and methods for generating antigen-binding units |
| US20050106700A1 (en) * | 2001-10-11 | 2005-05-19 | Tsuyoshi Nomura | Method of purifying recombinant fused protein and method of producing protein using the same |
| JP2004236504A (ja) * | 2003-02-03 | 2004-08-26 | Toyota Central Res & Dev Lab Inc | 酵素配列複合体及び固定化酵素配列複合体とそれらの製造方法、担体分子及び酵素 |
| US20050064509A1 (en) * | 2003-09-23 | 2005-03-24 | The Regents Of The University Of California | Use of templated self assembly to create novel multifunctional species |
| WO2005058244A2 (fr) * | 2003-12-15 | 2005-06-30 | Alexion Pharmaceuticals, Inc. | Nouveaux anticorps anti-dc-sign |
| CA2604032C (fr) * | 2005-04-06 | 2017-08-22 | Ibc Pharmaceuticals, Inc. | Methodes de generation de complexes lies stablement composes d'homodimeres, d'homotetrameres ou de dimeres de dimeres et utilisations associees |
| NZ578657A (en) * | 2007-02-02 | 2012-02-24 | Baylor Res Inst | Multivariable antigens complexed with targeting humanized monoclonal antibody |
| MX2009008140A (es) * | 2007-02-02 | 2009-10-26 | Baylor Res Inst | Vacunas a base de antigeno dirigido a dcir expresado en celulas que presentan antigeno. |
| TWI422594B (zh) * | 2007-02-02 | 2014-01-11 | Baylor Res Inst | 經由樹狀細胞去唾液酸糖蛋白受體(dc-asgpr)接合抗原呈現細胞之藥劑 |
-
2008
- 2008-01-31 NZ NZ578657A patent/NZ578657A/en not_active IP Right Cessation
- 2008-01-31 BR BRPI0807344-9A2A patent/BRPI0807344A2/pt not_active IP Right Cessation
- 2008-01-31 AU AU2008214077A patent/AU2008214077B2/en not_active Ceased
- 2008-01-31 WO PCT/US2008/052714 patent/WO2008097817A2/fr not_active Ceased
- 2008-01-31 MX MX2009008143A patent/MX2009008143A/es active IP Right Grant
- 2008-01-31 US US12/024,036 patent/US7786267B2/en active Active
- 2008-01-31 EP EP08728767.8A patent/EP2114985B1/fr active Active
- 2008-01-31 EP EP13178012.4A patent/EP2684889A3/fr not_active Withdrawn
- 2008-01-31 DK DK08728767T patent/DK2114985T3/en active
- 2008-01-31 JP JP2009548460A patent/JP5543785B2/ja not_active Expired - Fee Related
- 2008-01-31 NZ NZ592859A patent/NZ592859A/xx not_active IP Right Cessation
- 2008-01-31 ES ES08728767.8T patent/ES2536900T3/es active Active
- 2008-01-31 CN CN200880010934A patent/CN101657464A/zh active Pending
- 2008-01-31 KR KR1020097018149A patent/KR20090114425A/ko not_active Ceased
- 2008-01-31 CA CA2715042A patent/CA2715042C/fr active Active
- 2008-02-01 TW TW097104117A patent/TW200846371A/zh unknown
-
2009
- 2009-07-27 IL IL200092A patent/IL200092A0/en unknown
- 2009-08-04 ZA ZA200905447A patent/ZA200905447B/xx unknown
-
2010
- 2010-06-21 US US12/819,618 patent/US20100330115A1/en not_active Abandoned
-
2015
- 2015-10-19 US US14/887,151 patent/US20160031988A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2008214077B2 (en) | 2012-12-13 |
| EP2684889A3 (fr) | 2014-03-05 |
| US20100330115A1 (en) | 2010-12-30 |
| US20160031988A1 (en) | 2016-02-04 |
| US7786267B2 (en) | 2010-08-31 |
| KR20090114425A (ko) | 2009-11-03 |
| CN101657464A (zh) | 2010-02-24 |
| EP2684889A2 (fr) | 2014-01-15 |
| CA2715042C (fr) | 2021-02-02 |
| AU2008214077A1 (en) | 2008-08-14 |
| US20080254044A1 (en) | 2008-10-16 |
| CA2715042A1 (fr) | 2008-08-14 |
| EP2114985A2 (fr) | 2009-11-11 |
| JP2010518020A (ja) | 2010-05-27 |
| ES2536900T3 (es) | 2015-05-29 |
| WO2008097817A2 (fr) | 2008-08-14 |
| TW200846371A (en) | 2008-12-01 |
| EP2114985A4 (fr) | 2010-09-22 |
| BRPI0807344A2 (pt) | 2014-05-20 |
| EP2114985B1 (fr) | 2014-12-17 |
| MX2009008143A (es) | 2009-10-20 |
| DK2114985T3 (en) | 2015-03-30 |
| IL200092A0 (en) | 2010-04-15 |
| NZ578657A (en) | 2012-02-24 |
| NZ592859A (en) | 2012-05-25 |
| WO2008097817A3 (fr) | 2008-10-30 |
| JP5543785B2 (ja) | 2014-07-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL200092A0 (en) | Multivariable antigens complexed with targeting humanized monoclonal antibody | |
| IL202232A0 (en) | Novel rabbit antibody humanization methods and humanized rabbit antibodies | |
| IL206639A0 (en) | Humanized anti-human nkg2a monoclonal antibody | |
| IL239947A (en) | 21-il monoclonal antibody from human origin | |
| IL197928A (en) | A monoclonal antibody munched on steap-1, its immunoconjugates its uses | |
| IL205502A0 (en) | Humanized antibodies against tl1a | |
| ZA200807903B (en) | Humanized monoclonal antibodies to hepatocyte growth factor | |
| IL193871A0 (en) | Humanized anti-cd20 monoclonal antibody | |
| SG10201601279SA (en) | Monoclonal Antibody STRO-4 | |
| IL204835A0 (en) | Humanized antibody | |
| ZA200809662B (en) | Modified humanised anti-interleukin-18 antibodies | |
| IL243375B (en) | A human monoclonal antibody that binds to mesothelin | |
| EP2331579A4 (fr) | Anticorps monoclonaux | |
| IL200168A0 (en) | Monoclonal anti-cxcl13 antibodies | |
| EP2021373A4 (fr) | Anticorps monoclonal vcam-1 spécifique | |
| IL206147A0 (en) | Humanized antibody molecules specific for il-31 | |
| HUE037671T2 (hu) | Rák kezelésére szolgáló GT468 elleni monoklonális antitestek | |
| IL199974A0 (en) | Humanized antibodies against cxcr3 | |
| ZA201004770B (en) | Improved humanized anti-human x9-integrin antibody | |
| TWI348915B (en) | Anti-vegf monoclonal antibody | |
| GB0706965D0 (en) | Humanized antibody | |
| GB0706963D0 (en) | Humanized antibody | |
| GB0706964D0 (en) | Humanized antibody | |
| HK1147206A (en) | Anti-human il-21 monoclonal antibodies | |
| HK1146412A (en) | Humanized antibodies against tl1a |