ZA201407668B - Substituted pyrazole compounds as crac modulators - Google Patents

Substituted pyrazole compounds as crac modulators

Info

Publication number: ZA201407668B
Authority: ZA; South Africa
Prior art keywords: pyrazole compounds; substituted pyrazole; crac modulators; crac; modulators
Prior art date: 2012-05-02

Application number

ZA2014/07668A

Other languages

English (en)

Inventor

Rajender Kumar Kamboj

Venkata P Palle

Neelima Sinha

Zubair Abdul Wajid Shaikh

Kiran Chandrashekhar Kulkarni

Nilesh Raghunath Khedkar

Gokul Keruji Deshmukh

Nageswara Rao Irlapati

Original Assignee

Lupin Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2012-05-02

Filing date

2014-10-22

Publication date

2015-11-25

2014-10-22 Application filed by Lupin Ltd filed Critical Lupin Ltd

2015-11-25 Publication of ZA201407668B publication Critical patent/ZA201407668B/en

Links

NOIXNOMHHWGUTG-UHFFFAOYSA-N 2-[[4-[4-pyridin-4-yl-1-(2,2,2-trifluoroethyl)pyrazol-3-yl]phenoxy]methyl]quinoline Chemical class C=1C=C(OCC=2N=C3C=CC=CC3=CC=2)C=CC=1C1=NN(CC(F)(F)F)C=C1C1=CC=NC=C1 NOIXNOMHHWGUTG-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Rheumatology (AREA)
Pulmonology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Dermatology (AREA)
Immunology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ZA2014/07668A 2012-05-02 2014-10-22 Substituted pyrazole compounds as crac modulators ZA201407668B (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
IN6KO2012		2012-05-02
IN1474KO2012		2012-12-28
PCT/IB2013/053446 WO2013164773A1 (en)	2012-05-02	2013-05-01	Substituted pyrazole compounds as crac modulators

Publications (1)

Publication Number	Publication Date
ZA201407668B true ZA201407668B (en)	2015-11-25

Family

ID=48428566

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA2014/07668A ZA201407668B (en)	2012-05-02	2014-10-22	Substituted pyrazole compounds as crac modulators

Country Status (7)

Country	Link
US (2)	US9409898B2 (2)
EP (1)	EP2844656A1 (2)
AU (1)	AU2013255441B2 (2)
CA (1)	CA2871222A1 (2)
IN (1)	IN2014MN02127A (2)
WO (1)	WO2013164773A1 (2)
ZA (1)	ZA201407668B (2)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
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WO2015197187A1 (en) *	2014-06-24	2015-12-30	Grünenthal GmbH	Pyrazolyl-based carboxamides v
WO2015197188A1 (en) *	2014-06-24	2015-12-30	Grünenthal GmbH	Pyrazolyl-based carboxamides as crac inhibitors
US20180161388A1 (en)	2015-05-18	2018-06-14	Beth Israel Deaconess Medical Center, Inc.	Substance p, mast cell degranulation inhibitors, and peripheral neuropathy
WO2020053834A1 (en)	2018-09-14	2020-03-19	Rhizen Pharmaceuticals Sa	Compositions comprising a crac inhibitor and a corticosteroid and methods of use thereof
CA3121202A1 (en)	2018-11-30	2020-06-04	Nuvation Bio Inc.	Pyrrole and pyrazole compounds and methods of use thereof
AU2020286573A1 (en)	2019-06-06	2021-12-23	Basf Se	Fungicidal n-(pyrid-3-yl)carboxamides
CN110604735B (zh) *	2019-09-18	2022-10-25	华东师范大学	一种治疗肝纤维化、硬皮病的化合物及其应用
WO2021063735A1 (en)	2019-10-02	2021-04-08	Basf Se	New bicyclic pyridine derivatives

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AU751139B2 (en)	1997-10-13	2002-08-08	Astellas Pharma Inc.	Amide derivative
WO1999051580A1 (en)	1998-04-08	1999-10-14	Abbott Laboratories	Pyrazole inhibitors of cytokine production
WO1999062885A1 (en)	1998-06-05	1999-12-09	Boehringer Ingelheim Pharmaceuticals, Inc.	Substituted 1-(4-aminophenyl)pyrazoles and their use as anti-inflammatory agents
TWI376370B (en)	2003-07-23	2012-11-11	Synta Pharmaceuticals Corp	Compounds for inflammation and immune-related uses
KR20070057965A (ko)	2004-09-21	2007-06-07	신타 파마슈티칼스 코프.	염증 및 면역 관련 용도를 위한 화합물
KR20140018997A (ko)	2005-01-07	2014-02-13	신타 파마슈티칼스 코프.	염증 및 면역 관련 용도를 위한 화합물
EP1846388A4 (en)	2005-01-25	2011-12-07	Synta Pharmaceuticals Corp	THIOPHEN COMPOUNDS FOR IGNITIONS AND THE IMMUNE SYSTEM APPLICATIONS
PL1848435T3 (pl)	2005-01-25	2016-08-31	Synta Pharmaceuticals Corp	Związki przeciwko zapaleniom i zastosowania związane z odpornością
WO2007087429A2 (en)	2006-01-25	2007-08-02	Synta Pharmaceuticals Corp.	Phenyl and pyridyl compounds for inflammation and immune-related uses
TW200806641A (en)	2006-01-25	2008-02-01	Synta Pharmaceuticals Corp	Substituted aromatic compounds for inflammation and immune-related uses
TW200806290A (en)	2006-01-25	2008-02-01	Synta Pharmaceuticals Corp	Substituted biaryl compounds for inflammation and immune-related uses
US20070254926A1 (en)	2006-01-31	2007-11-01	Jun Jiang	Pyridylphenyl compounds for inflammation and immune-related uses
CA2695148A1 (en)	2007-08-01	2009-02-05	Synta Pharmaceuticals Corp.	Pyridine compounds for inflammation and immune-related uses
US8263641B2 (en)	2007-09-10	2012-09-11	Calcimedica, Inc.	Compounds that modulate intracellular calcium
US8389567B2 (en)	2007-12-12	2013-03-05	Calcimedica, Inc.	Compounds that modulate intracellular calcium
TWI392673B (zh)	2008-08-27	2013-04-11	Calcimedica Inc	調控細胞內鈣離子濃度之化合物
US8524763B2 (en)	2008-09-22	2013-09-03	Calcimedica, Inc.	Inhibitors of store operated calcium release
AU2009300318A1 (en)	2008-10-01	2010-04-08	Synta Pharmaceuticals Corp.	Compounds for inflammation and immune-related uses
EP2477982A4 (en)	2009-09-16	2013-04-03	Calcimedica Inc	COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM
US8377970B2 (en) *	2009-10-08	2013-02-19	Rhizen Pharmaceuticals Sa	Modulators of calcium release-activated calcium channel
AU2011291034A1 (en)	2010-08-20	2013-03-14	Grünenthal GmbH	Substituted cyclic carboxamide and urea derivatives as ligands of the vanilloid receptor
JP5387541B2 (ja)	2010-10-29	2014-01-15	住友電装株式会社	グロメット
AU2011322068B2 (en) *	2010-10-30	2015-11-05	Lupin Limited	Oxazoline and isoxazoline derivatives as CRAC modulators
JP2013545740A (ja)	2010-11-10	2013-12-26	グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング	バニロイド受容体リガンドとしての置換された複素芳香族カルボキサミド誘導体および尿素誘導体
CA2834928C (en)	2011-05-03	2017-10-17	Synta Pharmaceuticals Corp.	Compounds for inflammation and immune-related uses
WO2013059666A1 (en)	2011-10-19	2013-04-25	Calcimedica, Inc.	Compounds that modulate intracellular calcium
WO2013059677A1 (en)	2011-10-19	2013-04-25	Calcimedica, Inc.	Compounds that modulate intracellular calcium

2013
- 2013-05-01 WO PCT/IB2013/053446 patent/WO2013164773A1/en not_active Ceased
- 2013-05-01 AU AU2013255441A patent/AU2013255441B2/en not_active Expired - Fee Related
- 2013-05-01 US US14/398,161 patent/US9409898B2/en not_active Expired - Fee Related
- 2013-05-01 IN IN2127MUN2014 patent/IN2014MN02127A/en unknown
- 2013-05-01 CA CA 2871222 patent/CA2871222A1/en not_active Abandoned
- 2013-05-01 EP EP13722112.3A patent/EP2844656A1/en not_active Withdrawn
2014
- 2014-10-22 ZA ZA2014/07668A patent/ZA201407668B/en unknown
2016
- 2016-06-28 US US15/194,795 patent/US20160304507A1/en not_active Abandoned

Also Published As

Publication number	Publication date
CA2871222A1 (en)	2013-11-07
US9409898B2 (en)	2016-08-09
WO2013164773A1 (en)	2013-11-07
AU2013255441A1 (en)	2014-11-13
EP2844656A1 (en)	2015-03-11
AU2013255441B2 (en)	2017-11-09
IN2014MN02127A (2)	2015-09-11
US20160304507A1 (en)	2016-10-20
US20150111925A1 (en)	2015-04-23

Publication	Publication Date	Title
IL268013A (en)	2019-09-26	Tetrahydropyrazolopyrimidine compounds
ZA201407685B (en)	2015-11-25	Substituted pyridine compounds as crac modulators
AP2014007810A0 (en)	2014-07-31	Imidazopyrrolidinone compounds
IL237341A0 (en)	2015-04-30	Compounds that promote neurogenesis
GB201209138D0 (en)	2012-07-04	Compounds
GB201215357D0 (en)	2012-10-10	Compounds
GB201214750D0 (en)	2012-10-03	Compounds
EP2828262A4 (en)	2015-09-23	IMIDAZOTRIAZINONVERBINDUNGEN
GB201204985D0 (en)	2012-05-02	Compounds
ZA201508864B (en)	2017-07-26	Substituted heterocyclic compounds as crac modulators
GB201204125D0 (en)	2012-04-25	Compounds
ZA201407668B (en)	2015-11-25	Substituted pyrazole compounds as crac modulators
IL236091A0 (en)	2015-02-01	Pyrazole compounds are converted as lpar antagonists
PL2836495T3 (pl)	2016-11-30	Związki tetrahydropirolotiazynowe
GB201209096D0 (en)	2012-07-04	Compounds
ZA201407531B (en)	2016-05-25	Pyrazole compounds as sglt1 inhibitors
IL250684B (en)	2018-03-29	Processes for the preparation of 1-aryl-5-alkyl pyrazole
GB201219820D0 (en)	2012-12-19	Compounds
GB201217310D0 (en)	2012-11-14	Compounds
ZA201303800B (en)	2014-07-30	Pyrazole compounds
GB201223429D0 (en)	2013-02-06	Compounds
GB201220029D0 (en)	2012-12-19	Compounds
GB201219819D0 (en)	2012-12-19	Compounds
GB201218799D0 (en)	2012-12-05	Compounds
GB201218776D0 (en)	2012-12-05	Compounds