ZA735660B - Process for preparing 2-amino and 4-amino-quinazolines - Google Patents

Process for preparing 2-amino and 4-amino-quinazolines

Info

Publication number: ZA735660B
Authority: ZA; South Africa
Prior art keywords: amino; quinazolines; preparing
Prior art date: 1972-09-09

Application number

ZA735660A

Other languages

English (en)

Inventor

J Danillewicz

J Kemp

J Wright

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1972-09-09

Filing date

1973-08-20

Publication date

1974-07-31

1973-08-20 Application filed by Pfizer filed Critical Pfizer

1974-07-31 Publication of ZA735660B publication Critical patent/ZA735660B/xx

Links

GOJUJUVQIVIZAV-UHFFFAOYSA-N 2-amino-4,6-dichloropyrimidine-5-carbaldehyde Chemical group NC1=NC(Cl)=C(C=O)C(Cl)=N1 GOJUJUVQIVIZAV-UHFFFAOYSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
DRYRBWIFRVMRPV-UHFFFAOYSA-N quinazolin-4-amine Chemical class C1=CC=C2C(N)=NC=NC2=C1 DRYRBWIFRVMRPV-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

ZA735660A 1972-09-09 1973-08-20 Process for preparing 2-amino and 4-amino-quinazolines ZA735660B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB4199272A GB1383409A (en)	1972-09-09	1972-09-09	Derivatives of 2-amino- and 4-amino-quinazoline and pharmaceutical compositions containing them

Publications (1)

Publication Number	Publication Date
ZA735660B true ZA735660B (en)	1974-07-31

Family

ID=10422335

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA735660A ZA735660B (en)	1972-09-09	1973-08-20	Process for preparing 2-amino and 4-amino-quinazolines

Country Status (17)

Country	Link
US (1)	US3960861A (de)
JP (1)	JPS4985078A (de)
AR (1)	AR203373A1 (de)
AT (1)	AT330785B (de)
BE (1)	BE804558A (de)
CA (1)	CA995673A (de)
DE (2)	DE2366106C2 (de)
DK (1)	DK131725C (de)
ES (1)	ES418612A1 (de)
FR (1)	FR2198751B1 (de)
GB (1)	GB1383409A (de)
IE (1)	IE38318B1 (de)
IN (2)	IN139088B (de)
LU (1)	LU68373A1 (de)
NL (1)	NL161152C (de)
SU (1)	SU555850A3 (de)
ZA (1)	ZA735660B (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4044136A (en) *	1972-09-09	1977-08-23	Pfizer Inc.	Aminoquinazoline therapeutic agents
GR79603B (de) *	1982-07-24	1984-10-31	Pfizer
DE3464247D1 (de) *	1983-06-28	1987-07-23	Ciba Geigy Ag	Chromogenic quinazoline compounds
DK0556310T3 (da) *	1990-11-06	1995-08-21	Pfizer	Quinazolinderivater til forhøjelse af antitumoraktivitet
KR0144833B1 (ko) *	1992-12-28	1998-07-15	김태훈	신규의 퀴나졸린 유도체 및 그의 제조방법
DE4338396A1 (de) *	1993-11-10	1995-05-11	Basf Ag	N-Substituierte Azabicycloalkan-Derivate, ihre Herstellung und Verwendung
IT1286302B1 (it) *	1996-04-10	1998-07-08	Rotta Research Lab	Chinazoline-4-amino-2-(piperidino-1-il-4-sostituite) ad attivita' anti-ipertensiva, procedimento per la loro preparazione e loro uso
IN188411B (de)	1997-03-27	2002-09-21	Yuhan Corp
KR100272471B1 (ko)	1998-11-17	2000-11-15	김선진	신규의 피리미딘 유도체 및 그의 제조방법
US6900220B2 (en)	2001-01-02	2005-05-31	Syntex (U.S.A.) Llc	Quinazolone derivatives as alpha 1A/B adrenergic receptor antagonists
EP1560816A1 (de) *	2002-07-05	2005-08-10	F. Hoffmann-La Roche Ag	Chinazoline derivate
MX2009001036A (es) *	2006-08-04	2009-04-23	Merz Pharma Gmbh & Co Kgaa	Pirazolopirimidinas, proceso para su preparacion y su uso como medicina.
US8871756B2 (en) *	2011-08-11	2014-10-28	Hoffmann-La Roche Inc.	Compounds for the treatment and prophylaxis of Respiratory Syncytial Virus disease
WO2015018797A2 (en) *	2013-08-05	2015-02-12	Haplogen Gmbh	Antiviral compounds
AR099134A1 (es) *	2014-01-24	2016-06-29	Hoffmann La Roche	Procedimiento para la preparación de n-[(3-aminooxetán-3-il)metil]-2-(1,1-dioxo-3,5-dihidro-1,4-benzotiazepín-4-il)-6-metil-quinazolín-4-amina
EP3298017B1 (de)	2015-05-20	2019-08-14	H. Hoffnabb-La Roche Ag	Verbindungen zur behandlung von spinaler muskelatrophie
EP3322704B1 (de)	2015-07-16	2019-11-27	H. Hoffnabb-La Roche Ag	Krystalline form des n-[(3-amino-3-oxetanyl)methyl]-2-(2,3-dihydro-1,1-dioxido-1,4-benzothiazepin-4(5h)-yl)-6-methyl-4-quinazolinamins zur behandlung von infektionen durch das respiratorische synzytialvirus (rsv)
JP6659841B2 (ja)	2015-11-12	2020-03-04	エフ．ホフマン−ラロシュアーゲーＦ．Ｈｏｆｆｍａｎｎ−ＬａＲｏｃｈｅＡｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ	脊髄性筋萎縮症を処置するための組成物
IL294124B2 (en)	2015-12-10	2024-02-01	Ptc Therapeutics Inc	Methods for treating huntington's disease
WO2017097728A1 (en)	2015-12-10	2017-06-15	F. Hoffmann-La Roche Ag	Bridged piperidine derivatives
FR3061494B1 (fr)	2016-12-29	2020-07-03	Arkema France	Procede de synthese de dithiocarbamates cycliques fonctionnalises
US11407753B2 (en)	2017-06-05	2022-08-09	Ptc Therapeutics, Inc.	Compounds for treating Huntington's disease
US11382918B2 (en)	2017-06-28	2022-07-12	Ptc Therapeutics, Inc.	Methods for treating Huntington's Disease
WO2019005993A1 (en)	2017-06-28	2019-01-03	Ptc Therapeutics, Inc.	METHODS OF TREATING HUNTINGTON'S DISEASE
MX2020009957A (es)	2018-03-27	2021-01-15	Ptc Therapeutics Inc	Compuestos para el tratamiento de enfermedad de hungtinton.
PL3814357T3 (pl)	2018-06-27	2024-09-16	Ptc Therapeutics, Inc.	Związki heterocykliczne i heteroarylowe do leczenia choroby huntingtona
EP3814360B8 (de)	2018-06-27	2024-11-06	PTC Therapeutics, Inc.	Heteroaryl verbindungen zur behandlung von morbus huntington
EP3814345B8 (de)	2018-06-27	2024-10-30	PTC Therapeutics, Inc.	Heteroaryl verbindungen zur behandlung von morbus huntington
WO2020231977A1 (en)	2019-05-13	2020-11-19	Ptc Therapeutics, Inc.	Compounds for treating huntington's disease

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2945859A (en) *		1960-07-19		Diaminoquinazolines and method of
BE501634A (de) *	1950-03-02
US3155572A (en) *	1959-04-13	1964-11-03	Merck & Co Inc	Compositions and methods for treating coccidiosis
GB1062357A (en) *	1965-03-23	1967-03-22	Pfizer & Co C	Quinazolone derivatives
GB1131126A (en) *	1966-03-10	1968-10-23	Pfizer Ltd	2-vinyl-1,4-dihydroquinazoline derivatives
US3511836A (en) *	1967-12-13	1970-05-12	Pfizer & Co C	2,4,6,7-tetra substituted quinazolines
US3637701A (en) *	1969-03-03	1972-01-25	Sandoz Ag	Certain nitrate derivatives of 4-aminoquinazolines
US3635979A (en) *	1969-09-29	1972-01-18	Pfizer	Certain 6- and/or 7-alkoxy-substituted-2 4-bis(disubstituted amino) quinazolines
US3669968A (en) *	1970-05-21	1972-06-13	Pfizer	Trialkoxy quinazolines

1972
- 1972-09-09 GB GB4199272A patent/GB1383409A/en not_active Expired
1973
- 1973-08-20 ZA ZA735660A patent/ZA735660B/xx unknown
- 1973-08-21 IN IN1920/CAL/73A patent/IN139088B/en unknown
- 1973-08-30 DK DK478273*A patent/DK131725C/da active
- 1973-08-31 CA CA180,089A patent/CA995673A/en not_active Expired
- 1973-09-03 IE IE1560/73A patent/IE38318B1/xx unknown
- 1973-09-03 AR AR249880A patent/AR203373A1/es active
- 1973-09-04 JP JP48098934A patent/JPS4985078A/ja active Pending
- 1973-09-05 US US05/394,491 patent/US3960861A/en not_active Expired - Lifetime
- 1973-09-06 DE DE2366106A patent/DE2366106C2/de not_active Expired
- 1973-09-06 DE DE2345064A patent/DE2345064C3/de not_active Expired
- 1973-09-06 AT AT774573A patent/AT330785B/de active
- 1973-09-06 BE BE135402A patent/BE804558A/xx unknown
- 1973-09-07 LU LU68373A patent/LU68373A1/xx unknown
- 1973-09-07 NL NL7312350.A patent/NL161152C/xx not_active IP Right Cessation
- 1973-09-07 FR FR7332315A patent/FR2198751B1/fr not_active Expired
- 1973-09-08 ES ES418612A patent/ES418612A1/es not_active Expired
1975
- 1975-01-08 SU SU2095549A patent/SU555850A3/ru active
- 1975-07-11 IN IN1357/CAL/75A patent/IN141109B/en unknown

Also Published As

Publication number	Publication date
LU68373A1 (de)	1975-05-21
ES418612A1 (es)	1976-07-16
FR2198751B1 (de)	1977-01-28
NL161152B (nl)	1979-08-15
GB1383409A (en)	1974-02-12
DK131725C (da)	1976-01-26
US3960861A (en)	1976-06-01
DE2345064C3 (de)	1979-10-25
AR203373A1 (es)	1975-09-08
DE2345064A1 (de)	1974-04-11
AU5960673A (en)	1975-02-27
CA995673A (en)	1976-08-24
DE2345064B2 (de)	1979-03-08
SU555850A3 (ru)	1977-04-25
IE38318L (en)	1974-03-09
BE804558A (fr)	1974-03-06
JPS4985078A (de)	1974-08-15
IE38318B1 (en)	1978-02-15
AT330785B (de)	1976-07-26
DE2366106B1 (de)	1979-06-21
NL161152C (nl)	1980-01-15
DE2366106C2 (de)	1980-02-14
ATA774573A (de)	1975-10-15
IN139088B (de)	1976-05-08
NL7312350A (de)	1974-03-12
IN141109B (de)	1977-01-22
FR2198751A1 (de)	1974-04-05
DK131725B (da)	1975-08-25

Publication	Publication Date	Title
ZA735660B (en)	1974-07-31	Process for preparing 2-amino and 4-amino-quinazolines
IL42469A0 (en)	1973-08-29	Process for preparing urea
IL41809A0 (en)	1973-05-31	Trifluoromethyl-salicylanilides and process for preparing them
IL42183A0 (en)	1973-07-30	Acylamino-cephem-carboxylic acids and process for preparing them
EG11870A (en)	1978-09-30	Benzenesulfonyl-ureas and process for preparing them
IL40802A0 (en)	1973-03-30	Cephalosphorin derivatives and process for their preparation
MY7900116A (en)	1979-12-31	Process for the production of 6-piperazinyl-morphanthridinies and related triylcics
HU170929B (hu)	1977-10-28	Sposob poluchenija novykh 2-beta-gidroksi-3-al'fa-amino-steroidov i roizvodnykh
YU35118B (en)	1980-09-25	Process for preparing n-(1-ethyl-delta-pyrrolyly-methyl)-2-methoxy-5-sulfamidobenzamide
IL42558A0 (en)	1973-08-29	Benzenesulfonyl-ureas and process for preparing them
ZA733051B (en)	1974-12-24	Pyrazine derivatives and process for preparing
IL41352A0 (en)	1973-03-30	Nitroimidazolyl-triazolo-pyridazines and process for the preparation thereof
CA1034131A (en)	1978-07-04	2-amino-2-oxazolines and process for preparing them
ZA735342B (en)	1974-07-31	New cyclohexanepentol derivative and process for preparing the same
ZA721523B (en)	1973-10-31	17a-ethynylestriols and process for preparing same
AU478610B2 (en)	1975-02-27	Process for preparing 2-amino and 4-amino-quinazolines
IL42603A0 (en)	1973-08-29	Process for 6-alkoxypenicillanic and 7-alkoxycephalosporin acids
PH10211A (en)	1976-09-29	Novel evrninomicin derivatives and process for their preparation
IL38794A0 (en)	1972-04-27	Thienobenzazepines and process for preparing them
CA907617A (en)	1972-08-15	Process for preparing n-trityl-imidazoles and n-trityl-triazoles
CA895396A (en)	1972-03-14	Process for preparing polyamide-nitriles and polyiminoimides
IL42529A0 (en)	1973-08-29	Process for preparing desacetoxy-cephalosporin compounds and novel 3-nitrooxycepham compounds
CA915676A (en)	1972-11-28	Dexamethasone-17-valerate and process for preparing it
ZA733053B (en)	1974-04-24	Acylamino-cephem-carboxylic acids and process for preparing them
AU479922B2 (en)	1975-05-01	2-amino-2-oxazolines and process for preparing them