ZA772484B - Thiazole cardiovascular agents - Google Patents

Thiazole cardiovascular agents

Info

Publication number
ZA772484B
ZA772484B ZA00772484A ZA772484A ZA772484B ZA 772484 B ZA772484 B ZA 772484B ZA 00772484 A ZA00772484 A ZA 00772484A ZA 772484 A ZA772484 A ZA 772484A ZA 772484 B ZA772484 B ZA 772484B
Authority
ZA
South Africa
Prior art keywords
thiazole
cardiovascular agents
cardiovascular
agents
thiazole cardiovascular
Prior art date
Application number
ZA00772484A
Other languages
English (en)
Inventor
B Lewis
S Unger
K Untch
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of ZA772484B publication Critical patent/ZA772484B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C31/00—Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C31/13—Monohydroxylic alcohols containing saturated rings
    • C07C31/137—Monohydroxylic alcohols containing saturated rings polycyclic with condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/36—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/18—All rings being cycloaliphatic the ring system containing six carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA00772484A 1976-07-19 1977-04-25 Thiazole cardiovascular agents ZA772484B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/706,342 US4064258A (en) 1976-07-19 1976-07-19 Thiazole cardiovascular agents

Publications (1)

Publication Number Publication Date
ZA772484B true ZA772484B (en) 1978-11-29

Family

ID=24837146

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00772484A ZA772484B (en) 1976-07-19 1977-04-25 Thiazole cardiovascular agents

Country Status (16)

Country Link
US (1) US4064258A (da)
JP (1) JPS5312858A (da)
AU (1) AU2482177A (da)
BE (1) BE855014A (da)
DD (1) DD130731A5 (da)
DE (1) DE2721262A1 (da)
DK (1) DK238577A (da)
ES (1) ES458570A1 (da)
FR (1) FR2359131A1 (da)
GB (1) GB1550519A (da)
IL (1) IL51955A0 (da)
NL (1) NL7705879A (da)
NZ (1) NZ183945A (da)
SE (1) SE7704731L (da)
SU (1) SU645573A3 (da)
ZA (1) ZA772484B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4177280A (en) * 1978-07-03 1979-12-04 Syntex (U.S.A.) Inc. Bicyclo[3.1.0]hexyl-substituted carbonylaminophenoxy cardiovascular agents
US4477460A (en) * 1982-10-19 1984-10-16 Syntex (U.S.A.) Inc. Topical treatment of ocular hypertension
CA2450073C (en) 2001-07-25 2017-08-29 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
EP2671508B1 (en) 2005-04-28 2020-09-16 Proteus Digital Health, Inc. Pharma-informatics system
WO2009085033A1 (en) * 2007-12-27 2009-07-09 Cibus Llc Alkylester fatty acid blends and uses therefor
JP2010503710A (ja) 2006-09-18 2010-02-04 ラプトール ファーマシューティカル インコーポレイテッド 受容体関連タンパク質(rap)結合体の投与による肝障害の処置
ES2919563T3 (es) 2009-02-20 2022-07-27 Enhanx Biopharm Inc Sistema de administración de medicamentos a base de glutatión
KR20180114970A (ko) 2009-05-06 2018-10-19 라보라토리 스킨 케어, 인크. 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3897441A (en) * 1971-10-27 1975-07-29 Syntex Inc Certain thiazole-carboxamides and acylamino-thiazoles

Also Published As

Publication number Publication date
BE855014A (fr) 1977-11-25
FR2359131A1 (fr) 1978-02-17
NL7705879A (nl) 1978-01-23
SU645573A3 (ru) 1979-01-30
GB1550519A (en) 1979-08-15
NZ183945A (en) 1979-11-01
SE7704731L (sv) 1978-01-20
US4064258A (en) 1977-12-20
DK238577A (da) 1978-01-20
IL51955A0 (en) 1977-06-30
ES458570A1 (es) 1978-11-16
DE2721262A1 (de) 1978-01-26
DD130731A5 (de) 1978-04-26
AU2482177A (en) 1978-11-09
JPS5312858A (en) 1978-02-04

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