ZA78476B - 11 beta-substituted steroids - Google Patents

11 beta-substituted steroids

Info

Publication number: ZA78476B
Authority: ZA; South Africa
Prior art keywords: beta; substituted steroids; steroids; substituted
Prior art date: 1977-02-10

Application number

ZA00780476A

Other languages

English (en)

Inventor

G Overbeek

Original Assignee

Akzo Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-02-10

Filing date

1978-01-26

Publication date

1978-12-27

1978-01-26 Application filed by Akzo Nv filed Critical Akzo Nv

1978-12-27 Publication of ZA78476B publication Critical patent/ZA78476B/xx

Links

150000003431 steroids Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0081—Substituted in position 17 alfa and 17 beta
- C07J1/0085—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being a saturated hydrocarbon group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0059—Estrane derivatives substituted in position 17 by a keto group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
- C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0081—Substituted in position 17 alfa and 17 beta
- C07J1/0088—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J11/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
- C07J21/008—Ketals at position 17
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J33/005—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
- C07J33/007—Cyclic thioketals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ZA00780476A 1977-02-10 1978-01-26 11 beta-substituted steroids ZA78476B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
NL7701384A NL7701384A (nl)	1977-02-10	1977-02-10	Werkwijze voor het bereiden van nieuwe steroiden van de oestraanreeks.

Publications (1)

Publication Number	Publication Date
ZA78476B true ZA78476B (en)	1978-12-27

Family

ID=19827952

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA00780476A ZA78476B (en)	1977-02-10	1978-01-26	11 beta-substituted steroids

Country Status (16)

Country	Link
US (1)	US4292251A (fr)
JP (1)	JPS53101357A (fr)
AU (1)	AU519916B2 (fr)
BE (1)	BE863872A (fr)
CA (1)	CA1109458A (fr)
DE (1)	DE2805490A1 (fr)
DK (1)	DK62278A (fr)
ES (2)	ES466843A1 (fr)
FI (1)	FI780424A7 (fr)
FR (1)	FR2380300A1 (fr)
GB (1)	GB1595661A (fr)
IE (1)	IE46384B1 (fr)
LU (1)	LU79036A1 (fr)
NL (1)	NL7701384A (fr)
SE (1)	SE7801539L (fr)
ZA (1)	ZA78476B (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3042136A1 (de) *	1980-11-03	1982-06-09	Schering Ag, 1000 Berlin Und 4619 Bergkamen	Verfahren zur herstellung von 3 (beta), 7 (beta) -dihydroxy- (delta) (pfeil hoch)5(pfeil hoch) -steroiden
FR2528434B1 (fr) *	1982-06-11	1985-07-19	Roussel Uclaf	Nouveaux 19-nor steroides substitues en 11b et eventuellement en 2, leur procede de preparation et leur application comme medicament
AU572589B2 (en)	1983-12-14	1988-05-12	Upjohn Company, The	11(alpha)-difluoromethyl and (e)-and (z)-11-fluoromethylene steroids
US4567000A (en) *	1984-08-31	1986-01-28	The Upjohn Company	11-Difluoromethylene steroids
DE3702383A1 (de) *	1987-01-23	1988-08-04	Schering Ag	11ss-alkinylestrene und -estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate
FR2618783B1 (fr) *	1987-07-30	1991-02-01	Roussel Uclaf	Nouveaux 17-aryle steroides, leurs procedes et des intermediaires de preparation comme medicaments et les compositions pharmaceutiques les renfermant
US6037339A (en) *	1993-02-08	2000-03-14	Akzo Nobel N.V.	C-11 substituted steroids for treating menopausal complaints
US5710144A (en) *	1993-02-08	1998-01-20	Akzo Nobel N.V.	C-11 substituted steroids for treating menopausal complaints
ZA94715B (en) *	1993-02-08	1994-10-24	Akzo Nv	Steroids for treating menopausal complaints
CN1292702A (zh) *	1998-03-09	2001-04-25	阿克佐诺贝尔公司	新型避孕药盒
US20030083231A1 (en) *	1998-11-24	2003-05-01	Ahlem Clarence N.	Blood cell deficiency treatment method
CN1250563C (zh)	1999-05-04	2006-04-12	斯特拉坎有限公司	雄激素糖苷及其产生雄性征的活性
DE102007027637A1 (de)	2007-06-12	2008-12-18	Bayer Schering Pharma Aktiengesellschaft	17ß-Cyano-19-nor-androst-4-en-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007027636A1 (de) *	2007-06-12	2008-12-18	Bayer Schering Pharma Aktiengesellschaft	17ß-Cyano-18a-homo-19-nor-androst-4-en-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007027635A1 (de)	2007-06-12	2008-12-18	Bayer Schering Pharma Aktiengesellschaft	17ß-Cyano-19-androst-4-en-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007063501A1 (de)	2007-12-29	2009-07-02	Bayer Schering Pharma Aktiengesellschaft	15, 16-Methylen-17-hydroxy-19-nor-21-carbonsäure-Steroid y-Lacton-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007063500A1 (de)	2007-12-29	2009-07-02	Bayer Schering Pharma Aktiengesellschaft	17-(1'-Propenyl)-17-3'-oxidoestra-4-en-3-on-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007063503A1 (de)	2007-12-29	2009-07-02	Bayer Schering Pharma Aktiengesellschaft	17-Hydroxy-19-nor-21-carbonsäure-Steroid y-Lacton-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007063499A1 (de)	2007-12-29	2009-07-02	Bayer Schering Pharma Aktiengesellschaft	Steroid-17,17-Lactol-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007063498A1 (de)	2007-12-29	2009-07-02	Bayer Schering Pharma Aktiengesellschaft	15,16-Methylen-steroid-17,17-Lactol-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007063496A1 (de)	2007-12-29	2009-07-02	Bayer Schering Pharma Aktiengesellschaft	15,16-Methylen-17-(1'-propenyl)-17-3'-oxidoestra-4-en-3-on-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007063495A1 (de)	2007-12-29	2009-09-17	Bayer Schering Pharma Aktiengesellschaft	19-Nor-Steroidderivate mit einer 15α,16α-Methylengruppe und einem gesättigten 17,17-Spirolactonring, deren Verwendung sowie diese Derivate enthaltende Arzneimittel

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3299108A (en) *	1965-10-18	1967-01-17	Searle & Co	17alpha-alkynyl/alkenyl-13beta-alkyl-11-alkylgona-1, 3, 5 (10)-triene-3, 17beta-diols, ethers and esters thereof and intermediates thereto
US3346602A (en) *	1966-10-12	1967-10-10	Searle & Co	13beta-alkyl-11-alkylgona-1, 3, 5 (10)-trien-17-ones, ethers and esters thereof
US3465010A (en) *	1966-11-22	1969-09-02	Searle & Co	17 - (unsaturated hydrocarbon - substituted) 11,13beta - dialkylgon -4 - ene - 3,17beta-diols and esters thereof
US3377366A (en) *	1966-12-02	1968-04-09	Searle & Co	17alpha-alkynyl/alkenyl-11, 13beta-dialkylgon-5(10)-en-3-ones and esters thereof
GB1255345A (en)	1969-08-15	1971-12-01	Searle & Co	3-(3-OXO-11beta13beta-DIALKYL-17beta-HYDROXYGON-4-EN-17alpha-YL) PROPIONIC ACID gamma-LACTONE
US3755301A (en) *	1972-06-23	1973-08-28	Searle & Co	Manufacture of 11-alkyl steroids
FI54128C (fi) *	1972-12-09	1978-10-10	Akzo Nv	Foerfarande foer framstaellning av nya 11,11-alkylidensteroider ur oestran- och 19-norpregnanserien med foerbaettrad hormonell verkan
FR2235949B1 (fr) *	1973-06-18	1978-03-17	Roussel Uclaf
NL7317358A (nl) *	1973-12-19	1975-06-23	Akzo Nv	Nieuwe 11(beta)-alkylsteroiden van de oestraanreeks.
FR2377419A1 (fr) *	1977-01-13	1978-08-11	Roussel Uclaf	Nouveaux derives steroides 11b-substitues 1,3,5 (10) trieniques, leur procede de preparation et leur application comme medicament

1977
- 1977-02-10 NL NL7701384A patent/NL7701384A/xx not_active Application Discontinuation
1978
- 1978-01-26 IE IE178/78A patent/IE46384B1/en unknown
- 1978-01-26 ZA ZA00780476A patent/ZA78476B/xx unknown
- 1978-01-27 GB GB3424/78A patent/GB1595661A/en not_active Expired
- 1978-01-31 US US05/873,784 patent/US4292251A/en not_active Expired - Lifetime
- 1978-02-08 AU AU33103/78A patent/AU519916B2/en not_active Expired
- 1978-02-09 DE DE19782805490 patent/DE2805490A1/de not_active Withdrawn
- 1978-02-09 SE SE7801539A patent/SE7801539L/xx unknown
- 1978-02-09 JP JP1401078A patent/JPS53101357A/ja active Pending
- 1978-02-09 CA CA296,519A patent/CA1109458A/fr not_active Expired
- 1978-02-09 LU LU79036A patent/LU79036A1/fr unknown
- 1978-02-09 ES ES466843A patent/ES466843A1/es not_active Expired
- 1978-02-09 FI FI780424A patent/FI780424A7/fi not_active Application Discontinuation
- 1978-02-10 BE BE185089A patent/BE863872A/fr unknown
- 1978-02-10 DK DK62278A patent/DK62278A/da unknown
- 1978-02-10 FR FR7803781A patent/FR2380300A1/fr active Granted
- 1978-11-16 ES ES475164A patent/ES475164A1/es not_active Expired

Also Published As

Publication number	Publication date
US4292251A (en)	1981-09-29
CA1109458A (fr)	1981-09-22
IE46384B1 (en)	1983-05-18
NL7701384A (nl)	1978-08-14
AU519916B2 (en)	1982-01-07
FR2380300A1 (fr)	1978-09-08
JPS53101357A (en)	1978-09-04
FI780424A7 (fi)	1978-07-11
IE780178L (en)	1978-08-10
BE863872A (fr)	1978-08-10
AU3310378A (en)	1979-08-16
DE2805490A1 (de)	1978-08-17
ES466843A1 (es)	1979-06-01
ES475164A1 (es)	1979-06-16
GB1595661A (en)	1981-08-12
FR2380300B1 (fr)	1981-05-08
SE7801539L (sv)	1978-08-11
DK62278A (da)	1978-08-11
LU79036A1 (fr)	1978-06-26

Publication	Publication Date	Title
JPS5492201A (en)	1979-07-21	Sounddproof material
ZA78476B (en)	1978-12-27	11 beta-substituted steroids
JPS53144592A (en)	1978-12-15	122alkyll147*100tetrazacyclotridecane
JPS5484554A (en)	1979-07-05	11nn466diiooaminoglycocyl*133diamino sicritol derivatives
AU3526278A (en)	1979-10-25	L-sucrose
CS394878A2 (en)	1985-06-13	Zpusob pripravy produktu obsahujiciho fruktozu ze sacharozy
JPS5467199A (en)	1979-05-30	Radiationnshielding nonnelectroconductive material
MTP837B (en)	1979-10-22	Derivatives 2 finino-imidazolidire
JPS53130685A (en)	1978-11-14	11substitutedd33amimoo677dialkoxyy12*44 benzothiadiazinee11oxides
JPS54163581A (en)	1979-12-26	2*22di substitutedd77substituteddchromann44 onee55carboxyaldehyde
JPS5398981A (en)	1978-08-29	Semiisynthesis 4**aminoooreandomycine derivative
JPS5412313A (en)	1979-01-30	Glycerylltrii3555trimethylhexanoate
JPS5419978A (en)	1979-02-15	1244oxadiazol derivative
JPS5463095A (en)	1979-05-21	Semiisynthesized 4**ureiddoleandomycin derivative
AU3533578A (en)	1979-10-25	Micro-mill-mixer
JPS5476586A (en)	1979-06-19	2*44diaminoo55benzylpyrimidines
JPS5466657A (en)	1979-05-29	55isopropyll11oxaspiro24*heptoo44ene
JPS5388626A (en)	1978-08-04	Complex portion material
JPS5388627A (en)	1978-08-04	Complex portion material
JPS5431433A (en)	1979-03-08	Heattinsulating fireeresistant material
AU3355078A (en)	1979-08-30	Aryl-hexafuranosides
JPS53112827A (en)	1978-10-02	Novel 11phenyll22aminoo133 propanediolennalkyl derivative
CS610278A1 (en)	1985-07-16	Zarizeni pro dopravu kapalin v nadobach
JPS5484574A (en)	1979-07-05	Andiotensin 2 derivative
JPS53149990A (en)	1978-12-27	Semiisynthesis 4**sulfonylaminoo oreando mycine derivative