ZA787156B - 4a-aryl-octahydro-1h-2-pyrindines - Google Patents

4a-aryl-octahydro-1h-2-pyrindines

Info

Publication number
ZA787156B
ZA787156B ZA787156A ZA787156A ZA787156B ZA 787156 B ZA787156 B ZA 787156B ZA 787156 A ZA787156 A ZA 787156A ZA 787156 A ZA787156 A ZA 787156A ZA 787156 B ZA787156 B ZA 787156B
Authority
ZA
South Africa
Prior art keywords
pyrindines
octahydro
aryl
Prior art date
Application number
ZA787156A
Other languages
English (en)
Inventor
D Zimmerman
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ZA787156B publication Critical patent/ZA787156B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA787156A 1977-12-27 1978-12-20 4a-aryl-octahydro-1h-2-pyrindines ZA787156B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86489977A 1977-12-27 1977-12-27

Publications (1)

Publication Number Publication Date
ZA787156B true ZA787156B (en) 1980-08-27

Family

ID=25344312

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA787156A ZA787156B (en) 1977-12-27 1978-12-20 4a-aryl-octahydro-1h-2-pyrindines

Country Status (24)

Country Link
EP (1) EP0002937A1 (fr)
JP (1) JPS5498770A (fr)
AR (1) AR221352A1 (fr)
AU (1) AU4286678A (fr)
BE (1) BE872990A (fr)
BG (1) BG30927A3 (fr)
CA (1) CA1105026A (fr)
CS (1) CS203940B2 (fr)
DD (1) DD141156A5 (fr)
DK (1) DK577078A (fr)
ES (1) ES476385A1 (fr)
FI (1) FI783992A7 (fr)
FR (1) FR2413370A1 (fr)
GB (1) GB2010806A (fr)
GR (1) GR70349B (fr)
IL (1) IL56268A0 (fr)
IT (1) IT1101682B (fr)
LU (1) LU80719A1 (fr)
NZ (1) NZ189230A (fr)
PL (1) PL117572B1 (fr)
PT (1) PT68934A (fr)
RO (1) RO75805A (fr)
SU (1) SU841586A3 (fr)
ZA (1) ZA787156B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4579952A (en) * 1981-12-28 1986-04-01 E. I. Du Pont De Nemours And Company Intermediates for octahydrobenzofuro[3,2-e]isoquinolines
US4415736A (en) * 1981-12-28 1983-11-15 E. I. Du Pont De Nemours & Co. Certain tetrahydropyridine intermediates
US4537963A (en) * 1981-12-28 1985-08-27 E. I. Du Pont De Nemours And Company Intermediates for octahydrobenzofuro[3,2-E]isoquinolines
FR2617481B1 (fr) * 1987-07-03 1989-11-10 Roussel Uclaf Nouveaux derives de la tetrahydropyridine, leur procede de preparation et les intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
US8598164B2 (en) 2010-05-06 2013-12-03 Vertex Pharmaceuticals Incorporated Heterocyclic chromene-spirocyclic piperidine amides as modulators of ion channels
KR101923367B1 (ko) 2011-02-02 2018-12-04 버텍스 파마슈티칼스 인코포레이티드 이온 채널의 조절제로서의 피롤로피라진―스피로사이클릭 피페리딘 아미드
WO2012112743A1 (fr) 2011-02-18 2012-08-23 Vertex Pharmaceuticals Incorporated Amides de pipéridine spirocyclique chromanique en tant que modulateurs des canaux ioniques
US8828996B2 (en) 2011-03-14 2014-09-09 Vertex Pharmaceuticals Incorporated Morpholine-spirocyclic piperidine amides as modulators of ion channels
AU2014287471C1 (en) * 2013-07-10 2019-11-28 Vertex Pharmaceuticals Incorporated Fused piperidine amides as modulators of ion channels

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2336559A1 (de) * 1972-07-20 1974-01-31 Du Pont 4a-aryl-trans-decahydrochinoline und verfahren zu ihrer herstellung
AT330179B (de) * 1972-07-20 1976-06-25 Du Pont Verfahren zur herstellung von neuen 4a-aryl- transdecahydroisochinolinderivaten sowie deren optischen isomeren
PT67194B (en) * 1976-11-02 1979-03-23 Lilly Co Eli Process for preparing 4a-aryl-octahydro-1h-2-pyrindines

Also Published As

Publication number Publication date
PL211919A1 (pl) 1979-09-10
AU4286678A (en) 1979-07-05
RO75805A (fr) 1981-02-28
DK577078A (da) 1979-06-28
FR2413370A1 (fr) 1979-07-27
EP0002937A1 (fr) 1979-07-11
IL56268A0 (en) 1979-03-12
NZ189230A (en) 1981-05-15
CS203940B2 (en) 1981-03-31
SU841586A3 (ru) 1981-06-23
ES476385A1 (es) 1979-11-16
IT1101682B (it) 1985-10-07
DD141156A5 (de) 1980-04-16
PL117572B1 (en) 1981-08-31
AR221352A1 (es) 1981-01-30
CA1105026A (fr) 1981-07-14
BE872990A (fr) 1979-06-22
IT7831268A0 (it) 1978-12-22
GB2010806A (en) 1979-07-04
GR70349B (fr) 1982-09-23
LU80719A1 (fr) 1979-04-13
JPS5498770A (en) 1979-08-03
PT68934A (en) 1979-01-01
BG30927A3 (bg) 1981-09-15
FI783992A7 (fi) 1979-06-28

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