ZA803338B - Novel enkephalin derivatives - Google Patents

Novel enkephalin derivatives

Info

Publication number: ZA803338B
Authority: ZA; South Africa
Prior art keywords: enkephalin derivatives; novel; novel enkephalin; derivatives; enkephalin
Prior art date: 1979-06-21

Application number

ZA00803338A

Other languages

English (en)

Inventor

A Carr

R Farr

J Kane

Original Assignee

Richardson Merrell Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-06-21

Filing date

1980-06-04

Publication date

1981-05-27

1980-06-04 Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc

1981-05-27 Publication of ZA803338B publication Critical patent/ZA803338B/xx

Links

URLZCHNOLZSCCA-VABKMULXSA-N Leu-enkephalin Chemical class C([C@@H](C(=O)N[C@@H](CC(C)C)C(O)=O)NC(=O)CNC(=O)CNC(=O)[C@@H](N)CC=1C=CC(O)=CC=1)C1=CC=CC=C1 URLZCHNOLZSCCA-VABKMULXSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/82—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

ZA00803338A 1979-06-21 1980-06-04 Novel enkephalin derivatives ZA803338B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/050,940 US4236009A (en)	1979-06-21	1979-06-21	Method of preparing 4A-arylhexahydro-1H-2-pyrindines and 4A-aryloctahydroisoquinolines

Publications (1)

Publication Number	Publication Date
ZA803338B true ZA803338B (en)	1981-05-27

Family

ID=21968457

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA00803338A ZA803338B (en)	1979-06-21	1980-06-04	Novel enkephalin derivatives

Country Status (3)

Country	Link
US (1)	US4236009A (fr)
BE (1)	BE883943A (fr)
ZA (1)	ZA803338B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4419517A (en) *	1973-06-01	1983-12-06	E. I. Du Pont De Nemours & Co.	4a-Aryl-trans-decahydroisoquinolines
US4537963A (en) *	1981-12-28	1985-08-27	E. I. Du Pont De Nemours And Company	Intermediates for octahydrobenzofuro[3,2-E]isoquinolines
US4692528A (en) *	1981-12-28	1987-09-08	E. I. Du Pont De Nemours And Company	Intermediates for octahydrobenzofuro[3,2-e]isoquinolines
DK568482A (da) *	1981-12-28	1983-06-29	Du Pont	Fremgangsmaade til fremstilling af octahydrobenzofuro(3,2-e)-isoquinoliner med analgetisk og narkotisk-antagonistisk virkning samt intermediater til brug derved
US4421916A (en) *	1981-12-28	1983-12-20	E. I. Du Pont De Nemours & Co.	Intermediates for octahydrobenzofuro[3,2-e]isoquinolines
US4579952A (en) *	1981-12-28	1986-04-01	E. I. Du Pont De Nemours And Company	Intermediates for octahydrobenzofuro[3,2-e]isoquinolines
US4415736A (en) *	1981-12-28	1983-11-15	E. I. Du Pont De Nemours & Co.	Certain tetrahydropyridine intermediates
US4485109A (en) *	1982-05-07	1984-11-27	E. I. Du Pont De Nemours And Company	4-Aryl-4-piperidinecarbinols

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA734895B (en) *	1972-07-20	1974-06-26	Du Pont	Analgesigs and/or narcotic antagonists
US4001247A (en) *	1974-06-07	1977-01-04	Eli Lilly And Company	1-ethyl 3a-(substituted-phenyl) decahydroisoquinoline
US4029796A (en) *	1974-06-07	1977-06-14	Eli Lilly And Company	Novel N-cycloalkylmethyl decahydroisoquinolines for producing opiate-like analgesia
US4001248A (en) *	1974-06-07	1977-01-04	Eli Lilly And Company	N-cycloalkylmethyl decahydroisoquinolines
PT67194B (en) *	1976-11-02	1979-03-23	Lilly Co Eli	Process for preparing 4a-aryl-octahydro-1h-2-pyrindines

1979
- 1979-06-21 US US06/050,940 patent/US4236009A/en not_active Expired - Lifetime
1980
- 1980-06-04 ZA ZA00803338A patent/ZA803338B/xx unknown
- 1980-06-20 BE BE0/201125A patent/BE883943A/fr not_active IP Right Cessation

Also Published As

Publication number	Publication date
US4236009A (en)	1980-11-25
BE883943A (fr)	1980-10-16

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