ZA81374B - Process for obtaining human relaxin - Google Patents

Process for obtaining human relaxin

Info

Publication number: ZA81374B
Authority: ZA; South Africa
Prior art keywords: obtaining human; human relaxin; relaxin; obtaining; human
Prior art date: 1980-02-01

Application number

ZA81374A

Other languages

English (en)

Inventor

Mario Bigazzi

Original Assignee

Medipharm Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-02-01

Filing date

1981-01-20

Publication date

1982-08-25

1981-01-20 Application filed by Medipharm Ltd filed Critical Medipharm Ltd

1982-08-25 Publication of ZA81374B publication Critical patent/ZA81374B/xx

Links

BJRCFZKVYNDCJE-WBSNEMHCSA-N 99489-95-9 Chemical compound C([C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@@H]2CSSC[C@@H](C(=O)N[C@H](C(N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)NCC(=O)N2)[C@@H](C)CC)=O)CSSC[C@@H](C(NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@H](NC1=O)C(O)=O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(O)=O)[C@@H](C)CC)[C@@H](C)CC)C(C)C)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@@H](N)CCCCN)C(C)C)[C@@H](C)CC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H]1N(CCC1)C(=O)[C@@H](N)CCCNC(N)=N)C(C)C)C1=CC=C(O)C=C1 BJRCFZKVYNDCJE-WBSNEMHCSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/64—Relaxins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/85—Reproductive organs or embryos
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/85—Reproductive organs or embryos
- Y10S530/851—Placenta; amniotic fluid
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/85—Reproductive organs or embryos
- Y10S530/852—Sperm
- Y10S530/853—Ovary; eggs; embryos

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Endocrinology (AREA)
Medicinal Chemistry (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Toxicology (AREA)
Reproductive Health (AREA)
Gynecology & Obstetrics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pregnancy & Childbirth (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

ZA81374A 1980-02-01 1981-01-20 Process for obtaining human relaxin ZA81374B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/117,444 US4267101A (en)	1980-02-01	1980-02-01	Process for obtaining human relaxin from fetal membranes

Publications (1)

Publication Number	Publication Date
ZA81374B true ZA81374B (en)	1982-08-25

Family

ID=22372986

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA81374A ZA81374B (en)	1980-02-01	1981-01-20	Process for obtaining human relaxin

Country Status (18)

Country	Link
US (1)	US4267101A (fr)
JP (1)	JPS56127315A (fr)
AR (2)	AR227907A1 (fr)
AT (1)	AT372856B (fr)
AU (1)	AU540310B2 (fr)
BE (1)	BE887324A (fr)
CA (1)	CA1143286A (fr)
CH (1)	CH647530A5 (fr)
DE (1)	DE3102487C2 (fr)
DK (1)	DK44181A (fr)
ES (1)	ES498941A0 (fr)
FR (1)	FR2475047A1 (fr)
GB (1)	GB2068383B (fr)
IL (1)	IL61931A (fr)
IT (1)	IT8147648A0 (fr)
NL (1)	NL8100243A (fr)
SE (1)	SE8100614L (fr)
ZA (1)	ZA81374B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5320953A (en) *	1982-08-12	1994-06-14	Howard Florey Institute Of Experimental Physiology And Medicine	Process for synthesizing human H1-prorelaxin, H1-relaxin and fusion proteins thereof
EP0101309B1 (fr) *	1982-08-12	1991-01-16	Howard Florey Institute Of Experimental Physiology And Medicine	Clonage moléculaire et caractérisation de la séquence de gène codant pour la relaxine humaine
US5053488A (en) *	1982-08-12	1991-10-01	Howard Florey Institute Of Experimental Physiology & Medicine	Molecular cloning and characterization of a gene sequence coding for human relaxin
DE3236264A1 (de) *	1982-09-30	1984-04-05	Serono Pharmazeutische Präparate GmbH, 7800 Freiburg	Verfahren zur gewinnung von relaxin
IL70414A (en) *	1982-12-13	1991-06-10	Florey Howard Inst	Polypeptide having human h2-relaxin activity,double-stranded dna fragments coding therefor,vectors containing the dna fragments and methods for preparing the polypeptide,dna fragments and vectors
US5023321A (en) *	1982-12-13	1991-06-11	Howard Florey Institute Of Experimental Physiology & Medicine	Molecular cloning and characterization of a further gene sequence coding for human relaxin
EP0260149A1 (fr) *	1986-09-12	1988-03-16	Howard Florey Institute Of Experimental Physiology And Medicine	Prorélaxine humaine pour utilisation thérapeutique
WO1989007945A1 (fr) *	1988-02-26	1989-09-08	Genentech, Inc.	Formulation de relaxine humaine
US6348327B1 (en)	1991-12-06	2002-02-19	Genentech, Inc.	Non-endocrine animal host cells capable of expressing variant proinsulin and processing the same to form active, mature insulin and methods of culturing such cells
US5612051A (en) *	1995-11-17	1997-03-18	Yue; Samuel K.	Method of treating involuntary muscle dysfunction with relaxin hormone
US6251863B1 (en)	1998-09-08	2001-06-26	Samuel K. Yue	Method of preventing and treating symptoms of aging and neurodegenerative dysfunctions with relaxin
WO2005115435A2 (fr) *	2004-04-30	2005-12-08	Bas Medical, Inc.	Methodes et compositions de lutte contre les maladies de la croissance foetale par modulation de la relaxine

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2852432A (en) *	1953-08-11	1958-09-16	Warner Lambert Pharmaceutical	Process for purification of relaxin by ion exchange
US2852431A (en) *	1954-05-17	1958-09-16	Warner Lambert Pharmaceutical	Process for the extraction and purification of relaxin using trichloracetic acid
US2930737A (en) *	1955-11-15	1960-03-29	Princeton Lab Inc	Process for the isolation of relaxin using glacial acetic acid
US2995494A (en) *	1957-12-27	1961-08-08	Ortho Pharma Corp	Process for purifying relaxin

1980
- 1980-02-01 US US06/117,444 patent/US4267101A/en not_active Expired - Lifetime
1981
- 1981-01-19 IL IL61931A patent/IL61931A/xx unknown
- 1981-01-20 NL NL8100243A patent/NL8100243A/nl not_active Application Discontinuation
- 1981-01-20 ZA ZA81374A patent/ZA81374B/xx unknown
- 1981-01-22 AT AT0026281A patent/AT372856B/de not_active IP Right Cessation
- 1981-01-26 DE DE3102487A patent/DE3102487C2/de not_active Expired
- 1981-01-26 CA CA000369263A patent/CA1143286A/fr not_active Expired
- 1981-01-27 AU AU66614/81A patent/AU540310B2/en not_active Ceased
- 1981-01-28 IT IT8147648A patent/IT8147648A0/it unknown
- 1981-01-29 SE SE8100614A patent/SE8100614L/xx not_active Application Discontinuation
- 1981-01-29 FR FR8101698A patent/FR2475047A1/fr active Granted
- 1981-01-29 CH CH598/81A patent/CH647530A5/de not_active IP Right Cessation
- 1981-01-29 ES ES498941A patent/ES498941A0/es active Granted
- 1981-01-30 AR AR284142A patent/AR227907A1/es active
- 1981-01-30 BE BE0/203662A patent/BE887324A/fr not_active IP Right Cessation
- 1981-01-30 DK DK44181A patent/DK44181A/da not_active Application Discontinuation
- 1981-01-31 JP JP1222881A patent/JPS56127315A/ja active Granted
- 1981-02-02 GB GB8103103A patent/GB2068383B/en not_active Expired
1982
- 1982-02-09 AR AR288374A patent/AR227959A1/es active

Also Published As

Publication number	Publication date
BE887324A (fr)	1981-05-14
ES8203914A1 (es)	1982-05-01
AT372856B (de)	1983-11-25
FR2475047A1 (fr)	1981-08-07
AU540310B2 (en)	1984-11-08
GB2068383A (en)	1981-08-12
CH647530A5 (de)	1985-01-31
ES498941A0 (es)	1982-05-01
GB2068383B (en)	1983-05-11
JPS56127315A (en)	1981-10-06
IT8147648A0 (it)	1981-01-28
FR2475047B1 (fr)	1983-07-29
IL61931A0 (en)	1981-02-27
ATA26281A (de)	1983-04-15
IL61931A (en)	1984-06-29
SE8100614L (sv)	1981-08-02
AR227959A1 (es)	1982-12-30
NL8100243A (nl)	1981-09-01
AU6661481A (en)	1981-08-06
DK44181A (da)	1981-08-02
JPS6157809B2 (fr)	1986-12-09
DE3102487A1 (de)	1982-01-07
DE3102487C2 (de)	1983-06-16
AR227907A1 (es)	1982-12-30
US4267101A (en)	1981-05-12
CA1143286A (fr)	1983-03-22

Publication	Publication Date	Title
JPS56145295A (en)	1981-11-11	Method of obtaining pure recithin directly usable for physiological purpose
JPS5564300A (en)	1980-05-14	Human identification method
GB2087217B (en)	1984-05-02	Canning process
YU105283A (en)	1983-10-31	Process for obtaining 2-guanidino-4-heteroarylthiazoles
YU221581A (en)	1983-09-30	Process for obtaining isoxazolyl-benzamides
GB2068383B (en)	1983-05-11	Process for obtaining human relaxin
RO82720B (ro)	1984-07-30	Procedeu de stabilizare a unui agent antibacterian liofilizat de beta-lactama
YU149482A (en)	1984-12-31	Process for obtaining amido-benzamides
YU164481A (en)	1984-02-29	Process for obtaining isoxazolyl-imidazolidinone
DE3279301D1 (en)	1989-02-02	Blood pressuremeasuring apparatus
YU163582A (en)	1985-03-20	Process for obtaining s-benzylthiocarbamates
YU122181A (en)	1983-06-30	Process for obtaining carbapenam and carbapen-2-em
YU125882A (en)	1985-03-20	Process for obtaining imidazolyl-propionitrile
YU243681A (en)	1984-02-29	Process for obtaining buspyrone
YU193781A (en)	1984-02-29	Process for obtaining 11-hydroxy-13-oxa-prostaglandins
YU42584B (en)	1988-10-31	Process for obtaining 4-carbamoyloxy-oxazaphosphorine
YU71081A (en)	1983-10-31	Process for obtaining 2-haloacetamides
YU184881A (en)	1984-02-29	Process for obtaining 4-amino-12-dihydrocarbyl-pyrazolidine
DE3174506D1 (en)	1986-06-05	Imaging process
GB2082160B (en)	1984-03-14	Process for obtaining senarmontite
YU133980A (en)	1983-02-28	Process for obtaining estradiol-17-polyphosphate
YU68280A (en)	1983-12-31	Process for obtaining n-alkyl-n-nitroso-urea
YU43219B (en)	1989-06-30	Process for obtaining l-lyzine
JPS56112230A (en)	1981-09-04	Foot shape taking apparatus
BG31134A1 (en)	1981-11-16	Method for obtaining of tubocin s