ZA816712B - 1-ethyl-6-fluoro-1,4-dihydro-4-oxo 7-(1-piperazinyl)-3-quino-line carboxylic acid and metal salts thereof useful in burn therapy - Google Patents

1-ethyl-6-fluoro-1,4-dihydro-4-oxo 7-(1-piperazinyl)-3-quino-line carboxylic acid and metal salts thereof useful in burn therapy

Info

Publication number: ZA816712B
Authority: ZA; South Africa
Prior art keywords: piperazinyl; dihydro; oxo; fluoro; ethyl
Prior art date: 1980-10-02

Application number

ZA816712A

Other languages

English (en)

Inventor

Charles L Fox Jr

Shanta M Modak

Original Assignee

Fox Charles L Jun

Shanta M Modak

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-10-02

Filing date

1981-09-28

Publication date

1983-01-26

1981-09-28 Application filed by Fox Charles L Jun, Shanta M Modak filed Critical Fox Charles L Jun

1983-01-26 Publication of ZA816712B publication Critical patent/ZA816712B/xx

Links

229910052751 metal Chemical class 0.000 title abstract 3
239000002184 metal Chemical class 0.000 title abstract 3
OGJPXUAPXNRGGI-UHFFFAOYSA-N norfloxacin Chemical class C1=C2N(CC)C=C(C(O)=O)C(=O)C2=CC(F)=C1N1CCNCC1 OGJPXUAPXNRGGI-UHFFFAOYSA-N 0.000 title abstract 2
150000003839 salts Chemical class 0.000 title abstract 2
238000002560 therapeutic procedure Methods 0.000 title 1
229910052684 Cerium Inorganic materials 0.000 abstract 1
BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 abstract 1
HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract 1
ZMIGMASIKSOYAM-UHFFFAOYSA-N cerium Chemical compound [Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce] ZMIGMASIKSOYAM-UHFFFAOYSA-N 0.000 abstract 1
229910017052 cobalt Inorganic materials 0.000 abstract 1
239000010941 cobalt Substances 0.000 abstract 1
GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000012052 hydrophilic carrier Substances 0.000 abstract 1
229910052709 silver Inorganic materials 0.000 abstract 1
239000004332 silver Substances 0.000 abstract 1
229910052725 zinc Inorganic materials 0.000 abstract 1
239000011701 zinc Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Dermatology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Quinoline Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicinal Preparation (AREA)

ZA816712A 1980-10-02 1981-09-28 1-ethyl-6-fluoro-1,4-dihydro-4-oxo 7-(1-piperazinyl)-3-quino-line carboxylic acid and metal salts thereof useful in burn therapy ZA816712B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US19330780A	1980-10-02	1980-10-02

Publications (1)

Publication Number	Publication Date
ZA816712B true ZA816712B (en)	1983-01-26

Family

ID=22713084

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA816712A ZA816712B (en)	1980-10-02	1981-09-28	1-ethyl-6-fluoro-1,4-dihydro-4-oxo 7-(1-piperazinyl)-3-quino-line carboxylic acid and metal salts thereof useful in burn therapy

Country Status (13)

Country	Link
EP (1)	EP0049593B1 (da)
JP (1)	JPS57183762A (da)
AT (1)	ATE21692T1 (da)
AU (1)	AU546922B2 (da)
BR (1)	BR8106318A (da)
CA (1)	CA1208644A (da)
DE (1)	DE3175220D1 (da)
DK (1)	DK435781A (da)
ES (1)	ES8206514A1 (da)
IE (1)	IE52125B1 (da)
IL (1)	IL63945A (da)
PT (1)	PT73750B (da)
ZA (1)	ZA816712B (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3142854A1 (de) *	1981-10-29	1983-05-11	Bayer Ag, 5090 Leverkusen	1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7-piperazino-chinolin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
DE3308908A1 (de) *	1983-03-12	1984-09-13	Bayer Ag, 5090 Leverkusen	Bakterizide mittel
DE3318145A1 (de) *	1983-05-18	1984-11-22	Bayer Ag, 5090 Leverkusen	7-amino-1-cyclopropyl-6,8-difluor-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
US4551456A (en) *	1983-11-14	1985-11-05	Merck & Co., Inc.	Ophthalmic use of norfloxacin and related antibiotics
JPS61180771A (ja) *	1985-01-05	1986-08-13	バイエル・アクチエンゲゼルシヤフト	安定な抗バクテリア剤水溶液
FR2595355B1 (fr) *	1986-03-05	1988-11-25	Edmond Pharma Srl	Nouveau sel d'argent derive de quinolone, utile notamment comme antibacterien, et sa fabrication
DE3635062A1 (de) *	1986-10-15	1988-04-21	Bayer Ag	Neue metallsalze von 1-cyclopropyl-chinoloncarbonsaeuren und diese enthaltende arzneimittel
FR2665635A1 (fr) *	1990-08-10	1992-02-14	Merck Sharp & Dohme	Composition pharmaceutique fluide a base d'un complexe metallique et son procede de preparation.
US6200968B1 (en) *	1998-08-06	2001-03-13	Cephalon, Inc.	Particle-forming compositions containing fused pyrrolocarbazoles
US6863825B2 (en)	2003-01-29	2005-03-08	Union Oil Company Of California	Process for removing arsenic from aqueous streams
JP2008205418A (ja) *	2007-02-19	2008-09-04	Mikio Shimoyama	いつでもスイッチ
US8349764B2 (en)	2007-10-31	2013-01-08	Molycorp Minerals, Llc	Composition for treating a fluid
IN2012DN00829A (da) *	2009-07-06	2015-06-26	Molycorp Minerals Llc
US9233863B2 (en)	2011-04-13	2016-01-12	Molycorp Minerals, Llc	Rare earth removal of hydrated and hydroxyl species
US9975787B2 (en)	2014-03-07	2018-05-22	Secure Natural Resources Llc	Removal of arsenic from aqueous streams with cerium (IV) oxide compositions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS53141286A (en) *	1977-05-16	1978-12-08	Kyorin Seiyaku Kk	Novel substituted quinolinecarboxylic acid
JPS5466686A (en) *	1977-09-20	1979-05-29	Dainippon Pharmaceut Co Ltd	Quinoline-3-carboxylic acid derivative, its preparation, and pharmaceutical composition containig the same

1981
- 1981-09-24 IE IE2225/81A patent/IE52125B1/en unknown
- 1981-09-25 CA CA000386743A patent/CA1208644A/en not_active Expired
- 1981-09-27 IL IL63945A patent/IL63945A/xx unknown
- 1981-09-28 ZA ZA816712A patent/ZA816712B/xx unknown
- 1981-09-29 EP EP81304481A patent/EP0049593B1/en not_active Expired
- 1981-09-29 DE DE8181304481T patent/DE3175220D1/de not_active Expired
- 1981-09-29 AT AT81304481T patent/ATE21692T1/de active
- 1981-09-30 PT PT73750A patent/PT73750B/pt unknown
- 1981-10-01 DK DK435781A patent/DK435781A/da not_active Application Discontinuation
- 1981-10-01 ES ES505941A patent/ES8206514A1/es not_active Expired
- 1981-10-01 BR BR8106318A patent/BR8106318A/pt unknown
- 1981-10-02 AU AU76010/81A patent/AU546922B2/en not_active Ceased
- 1981-10-02 JP JP56157694A patent/JPS57183762A/ja active Pending

Also Published As

Publication number	Publication date
IL63945A0 (en)	1981-12-31
DK435781A (da)	1982-04-03
ATE21692T1 (de)	1986-09-15
DE3175220D1 (en)	1986-10-02
AU7601081A (en)	1982-04-08
IL63945A (en)	1986-03-31
PT73750B (en)	1983-01-13
ES505941A0 (es)	1982-08-16
EP0049593B1 (en)	1986-08-27
ES8206514A1 (es)	1982-08-16
IE812225L (en)	1982-04-02
AU546922B2 (en)	1985-09-26
CA1208644A (en)	1986-07-29
JPS57183762A (en)	1982-11-12
PT73750A (en)	1981-10-01
IE52125B1 (en)	1987-06-24
EP0049593A1 (en)	1982-04-14
BR8106318A (pt)	1982-06-22

Publication	Publication Date	Title
ZA816712B (en)	1983-01-26	1-ethyl-6-fluoro-1,4-dihydro-4-oxo 7-(1-piperazinyl)-3-quino-line carboxylic acid and metal salts thereof useful in burn therapy
NO162236C (no)	1989-11-29	Analogifremgangsmaate for fremstilling av terapeutisk aktive 1-cyklopropyl-6-fluor-1,4-dihydro-4-okso-7-(alkyl-1-piperazinyl)-3-kinolinkarboksylsyrer.
EP0013077A3 (en)	1980-10-01	Glass composition and its use in a therapeutic composition, in a subcutaneous implant or in a fertilizer, algicide, fungicide, or molluscicide
ZA921268B (en)	1992-11-25	2-substituted quinolines,processes for their preparation and their use in medicaments
ES8500931A1 (es)	1984-11-01	Procedimiento para la obtencion de acidos quinoloncarboxilicos
ZA877149B (da)	1988-04-12
MY101808A (en)	1992-01-31	Polycyclic quinoline, naphthyridine and pyrazinopyridine derivatives.
ES2051225A1 (es)	1994-06-01	Procedimiento de preparacion del acido 1-etil-6-fluoro-7-(pirrol-1-il) -1,4-dihidro-4-oxo-3-quinoleincarboxilico.
AU2039483A (en)	1985-04-11	Antimicrobial compositions containing 1-ethyl-6-fluoro-1,4- dihydro-4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinoline carboxylic acid or metal salts thereof & silver sulfadiazine
AU4344279A (en)	1979-07-26	Heat treatment of ferrous metals under controlled atmosphere
ES448933A1 (es)	1977-07-01	Metodo para preparar nuevos derivados de acidos carboxili- cos.
ES8303367A1 (es)	1983-02-01	Un procedimiento para la preparacion de un derivado de tetrazol.