ZA82125B - Substituted pyrimidin-2-ones and the salts thereof - Google Patents

Substituted pyrimidin-2-ones and the salts thereof

Info

Publication number: ZA82125B
Authority: ZA; South Africa
Prior art keywords: sup; sub; group; ring; heterocyclic
Prior art date: 1981-01-09

Application number

ZA82125A

Other languages

English (en)

Inventor

Tore Benneche

Kjell Undheim

Original Assignee

Nyegaard & Co As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-01-09

Filing date

1982-01-08

Publication date

1982-12-29

1982-01-08 Application filed by Nyegaard & Co As filed Critical Nyegaard & Co As

1982-12-29 Publication of ZA82125B publication Critical patent/ZA82125B/xx

Links

150000003839 salts Chemical class 0.000 title abstract 2
VTGOHKSTWXHQJK-UHFFFAOYSA-N pyrimidin-2-ol Chemical class OC1=NC=CC=N1 VTGOHKSTWXHQJK-UHFFFAOYSA-N 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 4
125000000623 heterocyclic group Chemical group 0.000 abstract 4
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
125000006615 aromatic heterocyclic group Chemical group 0.000 abstract 2
125000003710 aryl alkyl group Chemical group 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
230000002159 abnormal effect Effects 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
230000029936 alkylation Effects 0.000 abstract 1
238000005804 alkylation reaction Methods 0.000 abstract 1
125000000304 alkynyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000001589 carboacyl group Chemical group 0.000 abstract 1
125000002837 carbocyclic group Chemical group 0.000 abstract 1
230000004663 cell proliferation Effects 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
125000005842 heteroatom Chemical group 0.000 abstract 1
230000003647 oxidation Effects 0.000 abstract 1
238000007254 oxidation reaction Methods 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
238000006798 ring closing metathesis reaction Methods 0.000 abstract 1
125000003107 substituted aryl group Chemical group 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
- C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/38—One sulfur atom

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Cephalosporin Compounds (AREA)

ZA82125A 1981-01-09 1982-01-08 Substituted pyrimidin-2-ones and the salts thereof ZA82125B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB8100613		1981-01-09

Publications (1)

Publication Number	Publication Date
ZA82125B true ZA82125B (en)	1982-12-29

Family

ID=10518891

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA82125A ZA82125B (en)	1981-01-09	1982-01-08	Substituted pyrimidin-2-ones and the salts thereof

Country Status (12)

Country	Link
US (2)	US4596870A (da)
EP (1)	EP0056319B1 (da)
JP (1)	JPS57136575A (da)
AT (1)	ATE19242T1 (da)
AU (1)	AU7929482A (da)
CA (1)	CA1180710A (da)
DE (1)	DE3270525D1 (da)
DK (1)	DK5382A (da)
ES (2)	ES8304945A1 (da)
NO (1)	NO160514C (da)
NZ (1)	NZ199447A (da)
ZA (1)	ZA82125B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NO161440C (no) *	1982-02-24	1989-08-16	Nyegaard & Co As	Analogifremgangsmaate for fremstilling av fysiologisk aktive pyrimidin-2-oner.
GB2135992B (en) *	1983-01-11	1986-09-24	Nyegaard & Co As	Substituted pyrimidines and processes for their preparation
DE3461796D1 (en) *	1983-02-23	1987-02-05	Bayer Ag	Agent for regulating the growth of plants
GB8411291D0 (en) *	1984-05-02	1984-06-06	Nyegaard & Co As	Chemical compounds
US4864021A (en) *	1984-10-30	1989-09-05	Otsuka Pharmaceutical Co., Ltd.	5-fluorouracil derivatives
US4675321A (en) *	1986-02-07	1987-06-23	Merck & Co., Inc.	Substituted pyrimidines useful as calcium channel blockers
US4820711A (en) *	1987-05-15	1989-04-11	Pearlman Dale L	Method for treating actinic keratosis with cytotoxic agents
US4853388A (en) *	1987-05-15	1989-08-01	Pearlman Dale L	Method for treating psoriasis with cytotoxic agents
US4849426A (en) *	1987-05-15	1989-07-18	Pearlman Dale L	Method for treating actinic keratosis with cytotoxic agents
US8933239B1 (en) *	2013-07-16	2015-01-13	Dow Global Technologies Llc	Bis(aryl)acetal compounds
GB201321734D0 (en)	2013-12-09	2014-01-22	Ucb Pharma Sa	Therapeutic Agents

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1561290A (en) *	1975-10-16	1980-02-20	Nyegaard & Co As	Pyrimid - 2 - ones
US4044008A (en) *	1976-10-06	1977-08-23	Morton-Norwich Products, Inc.	1-[2-Hydroxy-3-(2-naphthoxy)propyl]-2(1H)pyrimidone hydrochloride
ES498337A0 (es) *	1980-01-07	1982-06-01	Nyegaard & Co As	Un procedimiento para la preparacion de 5-halo-pirimidin-2- onas
ATE16799T1 (de) *	1980-01-10	1985-12-15	Nyegaard & Co As	Pyrimidin-2-sulfide und ihre s-oxide zur verwendung in der medizin, die verbindungen enthaltende pharmazeutische zusammensetzungen, verfahren zu ihrer herstellung und die verbindungen an sich, sofern sie neu sind.
NO161440C (no) *	1982-02-24	1989-08-16	Nyegaard & Co As	Analogifremgangsmaate for fremstilling av fysiologisk aktive pyrimidin-2-oner.

1982
- 1982-01-08 JP JP57001098A patent/JPS57136575A/ja active Pending
- 1982-01-08 EP EP82300106A patent/EP0056319B1/en not_active Expired
- 1982-01-08 NZ NZ199447A patent/NZ199447A/en unknown
- 1982-01-08 NO NO820049A patent/NO160514C/no unknown
- 1982-01-08 ES ES508593A patent/ES8304945A1/es not_active Expired
- 1982-01-08 AU AU79294/82A patent/AU7929482A/en not_active Abandoned
- 1982-01-08 DK DK5382A patent/DK5382A/da not_active Application Discontinuation
- 1982-01-08 DE DE8282300106T patent/DE3270525D1/de not_active Expired
- 1982-01-08 CA CA000393785A patent/CA1180710A/en not_active Expired
- 1982-01-08 US US06/337,988 patent/US4596870A/en not_active Expired - Fee Related
- 1982-01-08 AT AT82300106T patent/ATE19242T1/de not_active IP Right Cessation
- 1982-01-08 ZA ZA82125A patent/ZA82125B/xx unknown
- 1982-12-01 ES ES517865A patent/ES8405771A1/es not_active Expired
1986
- 1986-04-08 US US06/849,271 patent/US4705791A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
NO160514B (no)	1989-01-16
US4705791A (en)	1987-11-10
NO820049L (no)	1982-07-12
ES508593A0 (es)	1983-03-16
ES517865A0 (es)	1984-06-16
ES8304945A1 (es)	1983-03-16
AU7929482A (en)	1982-07-15
DK5382A (da)	1982-07-10
DE3270525D1 (en)	1986-05-22
EP0056319A3 (en)	1982-10-27
NO160514C (no)	1989-04-26
ES8405771A1 (es)	1984-06-16
EP0056319A2 (en)	1982-07-21
EP0056319B1 (en)	1986-04-16
CA1180710A (en)	1985-01-08
NZ199447A (en)	1985-08-16
ATE19242T1 (de)	1986-05-15
US4596870A (en)	1986-06-24
JPS57136575A (en)	1982-08-23

Publication	Publication Date	Title
DE3362222D1 (en)	1986-04-03	Ether derivatives from substituted 1-hydroxyalkyl azoles, process for their preparation as well as their use as fungicides and plant-growth regulators
ES8800246A1 (es)	1987-11-01	Un procedimiento para la preparacion de silileteres.
ES8400100A1 (es)	1983-10-16	Procedimiento para la obtencion de derivados de 1-hidroxialquilazolilo sustituidos.
DE3270525D1 (en)	1986-05-22	Substituted pyrimidin-2-ones and the salts thereof
ES8406440A1 (es)	1984-07-01	Procedimiento para preparar derivados de 2-amino-3-acilamino-6-bencilamino-piridina
DE3163277D1 (en)	1984-05-30	Novel substituted oxonicotinates, their use as plant growth regulators and plant growth regulating compositions containing them
ES8505959A1 (es)	1985-06-16	Un procedimiento para preparar derivados de alcohol sustituidos con azol
DK162044C (da)	1992-02-10	Fungicidt indanylbenzamidderivat, fremgangsmaade til fremstilling heraf samt fungicidt middel indeholdende det
ES462671A1 (es)	1978-07-16	Procedimiento para la obtencion de sales de alfa-(4-bifeni- lil)-bencil-azolium.
DE3375917D1 (en)	1988-04-14	Thiomethylpyridine derivatives, process for their preparation and medicaments containing them
ES8800167A1 (es)	1987-11-01	Un procedimiento para preparar imidazol-5-carboximidatos
ES8403879A1 (es)	1984-04-01	Un procedimiento para la preparacion de pirimidin-2-onas sustituidas.
DE3561061D1 (en)	1988-01-07	N-(arylpropyl) azolylureas and fungicides containing them
ATE20466T1 (de)	1986-07-15	Triazolyl-ketonoxime und -dioxime, verfahren zu ihrer herstellung und ihre verwendung als pflanzenwachstumsregulatoren.
AU576888B2 (en)	1988-09-08	Benzodisultams
AU618444B2 (en)	1991-12-19	New process for separating optical isomers of 1,4-dihydropyridine derivatives
ATE5720T1 (de)	1984-01-15	2-pyridyloxyacetanilid-verbindungen, verfahren zu ihrer herstellung und ihre verwendung.