ZA845940B - New compounds derived from diphenyl-methylene-ethylamine - Google Patents

New compounds derived from diphenyl-methylene-ethylamine

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Publication number
ZA845940B
ZA845940B ZA845940A ZA845940A ZA845940B ZA 845940 B ZA845940 B ZA 845940B ZA 845940 A ZA845940 A ZA 845940A ZA 845940 A ZA845940 A ZA 845940A ZA 845940 B ZA845940 B ZA 845940B
Authority
ZA
South Africa
Prior art keywords
ethylamine
diphenyl
methylene
new compounds
compounds derived
Prior art date
Application number
ZA845940A
Other languages
English (en)
Inventor
Xavier D Cirera
Romeo R Andreoli
Pedro P Lloveras
Leonida Bruseghini
Jose P Irurre
Original Assignee
Espanola Farma Therapeut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Espanola Farma Therapeut filed Critical Espanola Farma Therapeut
Publication of ZA845940B publication Critical patent/ZA845940B/xx

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    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical
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    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
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    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
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    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
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    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
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    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms

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ZA845940A 1983-08-02 1984-08-01 New compounds derived from diphenyl-methylene-ethylamine ZA845940B (en)

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ES524680A ES8502099A1 (es) 1983-08-02 1983-08-02 Procedimiento de obtencion de nuevos compuestos derivados de la difenil-metilen-etilamina.

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EP (2) EP0357956A3 (de)
JP (1) JPH0625091B2 (de)
KR (1) KR900007198B1 (de)
AT (1) ATE59632T1 (de)
AU (1) AU580963B2 (de)
CA (1) CA1243018A (de)
DE (1) DE3483798D1 (de)
ES (1) ES8502099A1 (de)
NZ (1) NZ208691A (de)
ZA (1) ZA845940B (de)

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ES8502099A1 (es) * 1983-08-02 1984-12-16 Espanola Farma Therapeut Procedimiento de obtencion de nuevos compuestos derivados de la difenil-metilen-etilamina.
US4882351A (en) * 1987-10-14 1989-11-21 Roussel Uclaf Tricyclic compounds
IT1222986B (it) * 1987-10-23 1990-09-12 Texcontor Ets Derivati dell'efedrina esterificata aventi attivita' antiulcera prolungata nel tempo
US5508280A (en) * 1990-05-18 1996-04-16 Merrell Pharmaceuticals, Inc. 5H-Dibenzo (A,D) cycloheptenes as muscarinic receptor antagonists
AU7957191A (en) * 1990-05-18 1991-12-10 Merrell Dow Pharmaceuticals Inc. 5h-dibenzo(a,d)cycloheptenes as muscarinic receptor antagonists
JP2574733Y2 (ja) * 1991-09-04 1998-06-18 松下電器産業株式会社 車両用ハーネス案内装置
IL129123A (en) * 1996-10-04 2004-07-25 Novo Nordisk As Piperzines 1, 4 - Imaging methods, methods for their preparation and their use in the preparation of medicinal preparations
US6613905B1 (en) * 1998-01-21 2003-09-02 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
US7541365B2 (en) 2001-11-21 2009-06-02 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
TWI291467B (en) 2002-11-13 2007-12-21 Millennium Pharm Inc CCR1 antagonists and methods of use therefor
US9784726B2 (en) 2013-01-08 2017-10-10 Atrogi Ab Screening method, a kit, a method of treatment and a compound for use in a method of treatment
GB201714745D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714734D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714736D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714740D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201903832D0 (en) 2019-03-20 2019-05-01 Atrogi Ab New compounds and methods
GB202205895D0 (en) 2022-04-22 2022-06-08 Atrogi Ab New medical uses

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NL268880A (de) * 1960-09-13
NL6507535A (de) * 1965-06-11 1966-12-12
NL130988C (de) * 1966-07-21 Boehringer Mannheim Gmbh
JPS5111622B2 (de) * 1972-08-31 1976-04-13
US3906110A (en) * 1973-02-07 1975-09-16 Ciba Geigy Corp Antihypertensive {60 -(1-aralkylaminoalkyl)-aralkoxybenzyl alcohols
JPS525504B2 (de) * 1973-02-21 1977-02-14
JPS5231336B2 (de) * 1974-05-23 1977-08-13
JPS52105155A (en) * 1976-03-02 1977-09-03 Hokuriku Pharmaceutical Diphenylarylaminoalkanol quarternary salt derivatives and process for preparing same
NO154582C (no) * 1978-10-20 1986-11-05 Ferrosan Ab Analogifremgangsmaate for fremstilling av terapeutisk aktive difenyl-dibutylpiperazinkarboksamider.
US4308587A (en) * 1979-12-26 1981-12-29 Becton Dickinson And Company Apparatus for displaying at least two parameters of populations of particles on a cathode ray tube
IT1150959B (it) * 1980-06-10 1986-12-17 Simes Sostanze datate di attivita' antispastica vasale e procedimenti per la loro preparazione
US4381505A (en) * 1980-12-10 1983-04-26 The Arthur G. Russell Company, Incorporated System for displaying alphanumerical messages having stored and real time components
CA1160219A (en) * 1981-01-16 1984-01-10 Werner Aschwanden Cycloheptene derivatives
ES8502099A1 (es) * 1983-08-02 1984-12-16 Espanola Farma Therapeut Procedimiento de obtencion de nuevos compuestos derivados de la difenil-metilen-etilamina.
AU612437B2 (en) * 1987-12-14 1991-07-11 Kyowa Hakko Kogyo Co. Ltd. Tricyclic compounds

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CA1243018A (en) 1988-10-11
EP0132764B1 (de) 1991-01-02
EP0357956A2 (de) 1990-03-14
JPS60126265A (ja) 1985-07-05
US4835156A (en) 1989-05-30
ATE59632T1 (de) 1991-01-15
ES524680A0 (es) 1984-12-16
AU3131684A (en) 1985-02-07
US4835179A (en) 1989-05-30
AU580963B2 (en) 1989-02-09
JPH0625091B2 (ja) 1994-04-06
EP0132764A3 (en) 1985-12-04
NZ208691A (en) 1989-06-28
EP0132764A2 (de) 1985-02-13
KR850002261A (ko) 1985-05-10
EP0357956A3 (de) 1990-08-29
KR900007198B1 (ko) 1990-10-05
ES8502099A1 (es) 1984-12-16
DE3483798D1 (de) 1991-02-07
US5112826A (en) 1992-05-12

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