ZA847030B - Preparation of 2-(methylthiomethyl)-6-(trifluoromethyl)aniline from ortho-aminobenzotrifluoride - Google Patents

Preparation of 2-(methylthiomethyl)-6-(trifluoromethyl)aniline from ortho-aminobenzotrifluoride

Info

Publication number: ZA847030B
Authority: ZA; South Africa
Prior art keywords: succinimide; sulfilimine; hydrochloride salt; aminobenzotrifluoride; methylthiomethyl
Prior art date: 1983-09-07

Application number

ZA847030A

Other languages

English (en)

Inventor

Audrey Yeh Ku

John Paul Chupp

Terry Mack Balthazor

Original Assignee

Monsanto Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-09-07

Filing date

1984-09-06

Publication date

1985-06-26

1984-09-06 Application filed by Monsanto Co filed Critical Monsanto Co

1985-06-26 Publication of ZA847030B publication Critical patent/ZA847030B/xx

Links

AWUFEMPPABUXSZ-UHFFFAOYSA-N 2-(methylsulfanylmethyl)-6-(trifluoromethyl)aniline Chemical compound CSCC1=CC=CC(C(F)(F)F)=C1N AWUFEMPPABUXSZ-UHFFFAOYSA-N 0.000 title abstract 2
KZNICNPSHKQLFF-UHFFFAOYSA-N succinimide Chemical compound O=C1CCC(=O)N1 KZNICNPSHKQLFF-UHFFFAOYSA-N 0.000 abstract 8
GLBQVJGBPFPMMV-UHFFFAOYSA-N sulfilimine Chemical compound S=N GLBQVJGBPFPMMV-UHFFFAOYSA-N 0.000 abstract 6
JRNVZBWKYDBUCA-UHFFFAOYSA-N N-chlorosuccinimide Chemical compound ClN1C(=O)CCC1=O JRNVZBWKYDBUCA-UHFFFAOYSA-N 0.000 abstract 4
229960002317 succinimide Drugs 0.000 abstract 4
QCQCHGYLTSGIGX-GHXANHINSA-N 4-[[(3ar,5ar,5br,7ar,9s,11ar,11br,13as)-5a,5b,8,8,11a-pentamethyl-3a-[(5-methylpyridine-3-carbonyl)amino]-2-oxo-1-propan-2-yl-4,5,6,7,7a,9,10,11,11b,12,13,13a-dodecahydro-3h-cyclopenta[a]chrysen-9-yl]oxy]-2,2-dimethyl-4-oxobutanoic acid Chemical compound N([C@@]12CC[C@@]3(C)[C@]4(C)CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(O)=O)CC[C@]5(C)[C@H]4CC[C@@H]3C1=C(C(C2)=O)C(C)C)C(=O)C1=CN=CC(C)=C1 QCQCHGYLTSGIGX-GHXANHINSA-N 0.000 abstract 3
QMMFVYPAHWMCMS-UHFFFAOYSA-N Dimethyl sulfide Chemical compound CSC QMMFVYPAHWMCMS-UHFFFAOYSA-N 0.000 abstract 3
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
239000008346 aqueous phase Substances 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
238000006386 neutralization reaction Methods 0.000 abstract 2
239000012074 organic phase Substances 0.000 abstract 2
238000005191 phase separation Methods 0.000 abstract 2
RFIZPYFNEYSHKG-UHFFFAOYSA-N pyrrolidine-2,5-dione;sodium Chemical compound [Na].O=C1CCC(=O)N1 RFIZPYFNEYSHKG-UHFFFAOYSA-N 0.000 abstract 2
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
239000003054 catalyst Substances 0.000 abstract 1
230000003197 catalytic effect Effects 0.000 abstract 1
239000000460 chlorine Substances 0.000 abstract 1
229910052801 chlorine Inorganic materials 0.000 abstract 1
238000006464 oxidative addition reaction Methods 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1
230000009466 transformation Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C381/00—Compounds containing carbon and sulfur and having functional groups not covered by groups C07C301/00 - C07C337/00
- C07C381/10—Compounds containing sulfur atoms doubly-bound to nitrogen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Catalysts (AREA)

ZA847030A 1983-09-07 1984-09-06 Preparation of 2-(methylthiomethyl)-6-(trifluoromethyl)aniline from ortho-aminobenzotrifluoride ZA847030B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/530,153 US4496765A (en)	1983-09-07	1983-09-07	Preparation of 2-(methylthiomethyl)-6-(trifluoromethyl)aniline from ortho-aminobenzotrifluoride

Publications (1)

Publication Number	Publication Date
ZA847030B true ZA847030B (en)	1985-06-26

Family

ID=24112634

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA847030A ZA847030B (en)	1983-09-07	1984-09-06	Preparation of 2-(methylthiomethyl)-6-(trifluoromethyl)aniline from ortho-aminobenzotrifluoride

Country Status (7)

Country	Link
US (1)	US4496765A (fr)
EP (1)	EP0136995B1 (fr)
AT (1)	ATE30416T1 (fr)
BR (1)	BR8404474A (fr)
CA (1)	CA1218078A (fr)
DE (1)	DE3466980D1 (fr)
ZA (1)	ZA847030B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4777292A (en) *	1982-03-17	1988-10-11	Monsanto Company	Preparation of ortho-methyl anilines from ortho-amino benzyl sulfoxides
US4618713A (en) *	1983-09-07	1986-10-21	Monsanto Company	Preparation of 2'-methyl-2-haloacetanilides
DK0598396T3 (da) *	1992-11-18	1998-11-23	Boehringer Ingelheim Pharma	Forbedret fremgangsmåde til fremstilling af 3-amino-2-chlor-4-alkylpyridiner
US5654429A (en) *	1992-11-18	1997-08-05	Boehringer Ingelheim Pharma	Method for the preparation of 3-amino-2-chloro-4-alkylpyridines
AR015104A1 (es) *	1996-11-13	2001-04-18	Dowelanco	Compuestos de n-arilsulfilimina sustituidos, utiles como catalizadores en la preparacion de compuestos de n-arilarilsulfonamida; proceso para preparar dichos compuestos y su uso para catalizar dicha preparacion.
JP2004525128A (ja) *	2001-03-14	2004-08-19	イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー	オルトアルキル化の改良された方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3894034A (en) *	1973-01-29	1975-07-08	Ohio State Res Found	A process for producing azasulfonium salts
US3985756A (en) *	1973-01-29	1976-10-12	The Ohio State University Research Foundation	Process for producing azasulfonium salts and rearrangement thereof to thio-ethers
US3954797A (en) *	1973-12-28	1976-05-04	Chromalloy American Corporation	Process for preparing azasulfonium halide salts
US3960926A (en) *	1973-12-28	1976-06-01	The Ohio State University Research Foundation	Process for preparing azasulfonium halide salts
US4035375A (en) *	1975-02-27	1977-07-12	The Ohio State University Research Foundation	N-Substituted amino pyridines and derivatives thereof
US4172095A (en) *	1977-06-10	1979-10-23	Schering Corporation	Novel synthesis of 3-amino-2-methylbenzotrifluoride and the intermediates thereof

1983
- 1983-09-07 US US06/530,153 patent/US4496765A/en not_active Expired - Fee Related
1984
- 1984-09-04 DE DE8484870128T patent/DE3466980D1/de not_active Expired
- 1984-09-04 AT AT84870128T patent/ATE30416T1/de not_active IP Right Cessation
- 1984-09-04 EP EP84870128A patent/EP0136995B1/fr not_active Expired
- 1984-09-06 ZA ZA847030A patent/ZA847030B/xx unknown
- 1984-09-06 CA CA000462528A patent/CA1218078A/fr not_active Expired
- 1984-09-06 BR BR8404474A patent/BR8404474A/pt unknown

Also Published As

Publication number	Publication date
EP0136995B1 (fr)	1987-10-28
BR8404474A (pt)	1985-07-30
CA1218078A (fr)	1987-02-17
US4496765A (en)	1985-01-29
EP0136995A3 (en)	1985-12-11
ATE30416T1 (de)	1987-11-15
EP0136995A2 (fr)	1985-04-10
DE3466980D1 (en)	1987-12-03

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