ZA84757B - Novel pharmaceutically active 1,2,3,4,4a,5,10,10a-octahydrobenzo(g)quinoline derivatives,their production and use - Google Patents

Novel pharmaceutically active 1,2,3,4,4a,5,10,10a-octahydrobenzo(g)quinoline derivatives,their production and use

Info

Publication number
ZA84757B
ZA84757B ZA84757A ZA84757A ZA84757B ZA 84757 B ZA84757 B ZA 84757B ZA 84757 A ZA84757 A ZA 84757A ZA 84757 A ZA84757 A ZA 84757A ZA 84757 B ZA84757 B ZA 84757B
Authority
ZA
South Africa
Prior art keywords
octahydrobenzo
production
pharmaceutically active
quinoline derivatives
novel pharmaceutically
Prior art date
Application number
ZA84757A
Other languages
English (en)
Inventor
Max Peter Seiler
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of ZA84757B publication Critical patent/ZA84757B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/08—Aza-anthracenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA84757A 1983-02-01 1984-02-01 Novel pharmaceutically active 1,2,3,4,4a,5,10,10a-octahydrobenzo(g)quinoline derivatives,their production and use ZA84757B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH56083 1983-02-01

Publications (1)

Publication Number Publication Date
ZA84757B true ZA84757B (en) 1985-09-25

Family

ID=4189841

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA84757A ZA84757B (en) 1983-02-01 1984-02-01 Novel pharmaceutically active 1,2,3,4,4a,5,10,10a-octahydrobenzo(g)quinoline derivatives,their production and use

Country Status (17)

Country Link
US (1) US4692453A (fr)
JP (1) JPS59144761A (fr)
AU (1) AU571482B2 (fr)
BE (1) BE898761A (fr)
DE (1) DE3402601A1 (fr)
DK (1) DK40984A (fr)
FR (1) FR2540112B1 (fr)
GB (1) GB2134515B (fr)
IE (1) IE56653B1 (fr)
IL (1) IL70845A (fr)
IT (1) IT1199056B (fr)
LU (1) LU85191A1 (fr)
NL (1) NL8400259A (fr)
NZ (1) NZ206981A (fr)
PH (1) PH22782A (fr)
SE (1) SE8400445L (fr)
ZA (1) ZA84757B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT393997B (de) * 1983-06-22 1992-01-10 Heidelberger Druckmasch Ag Vorrichtung zur entnahme von bedruckten bogen fuer deren begutachtung
JP3005287B2 (ja) * 1989-07-13 2000-01-31 ファルマシア・アンド・アップジョン・カンパニー （１，２ｎ）および（３，２ｎ）―炭素環式―２―アミノテトラリン誘導体
US4939259A (en) * 1989-07-24 1990-07-03 Eli Lilly And Company 2-oxo-pyrido[2,3-g]quinoline derivatives
DE4114325A1 (de) * 1991-05-02 1992-11-05 Sandoz Ag Octahydrobenzo(g)chinolin, seine herstellung und verwendung
EP0586553A1 (fr) * 1991-05-20 1994-03-16 The Upjohn Company Derives de carboxamido-(3,2n)-2-aminotetralinecarbocyclique
US20090124651A1 (en) * 2007-08-31 2009-05-14 H. Lundbeck A/S Catecholamine derivatives and prodrugs thereof
JP2011525893A (ja) * 2008-06-27 2011-09-29 ハー・ルンドベック・アクチエゼルスカベット 新規のフェノールアミン類およびカテコールアミン類ならびにそのプロドラッグ
CR20200225A (es) 2017-11-24 2020-07-25 H Lundbeck As Nuevos fármacos de catecolamina para uso en el tratamiento de la enfermedad de parkinson
US11104697B2 (en) 2019-05-20 2021-08-31 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4AR,10AR)-7-hydroxy-1- propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11130775B2 (en) 2019-05-20 2021-09-28 H. Lundbeck A/S Solid forms of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11111263B2 (en) 2019-05-20 2021-09-07 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11168056B2 (en) 2019-05-20 2021-11-09 H. Lundbeck A/S Process for the manufacturing of (6aR,10aR)-7-propyl-6,6a,7,8,9,10,10a,11-octahydro-[1,3]dioxolo[4′,5′:5,6]benzo[1,2-G]quinoline and (4aR,10aR)-1-propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[G]quinoline-6,7-diol
EP3972600B1 (fr) 2019-05-21 2026-02-18 H. Lundbeck A/S Promédicaments de carbamate de catécholamine destinés à être utilisés dans le traitement de la maladie de parkinson
JP7562562B2 (ja) 2019-05-21 2024-10-07 ハー・ルンドベック・アクチエゼルスカベット パーキンソン病の治療に使用するための新規なカテコールアミンプロドラッグ
EP3972971A1 (fr) 2019-05-21 2022-03-30 H. Lundbeck A/S Nouveaux promédicaments de catécholamine destinés à être utilisés dans le traitement de maladies de parkinson
JP7641234B2 (ja) 2019-05-21 2025-03-06 ハー・ルンドベック・アクチエゼルスカベット パーキンソン病の治療に使用するための新規なカテコールアミンプロドラッグ

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3639411A (en) * 1968-05-09 1972-02-01 Sterling Drug Inc 1-substituted-2-(phenyl or benzyl)-3- or 3 3 - piperidine(mono or dicarboxylic) acids and esters thereo fand octahydrobenzo(g) - quinolines and hexahydro-5h-inden (12-b)pyridines produced therefrom
US3839338A (en) * 1968-05-09 1974-10-01 W Michne 1,2,3,4,4A,5,10,10A-OCTAHYDROBENZO{8 g{9 QUINOLINES
US3898235A (en) * 1970-12-02 1975-08-05 Sterling Drug Inc Octahydrobenzo {8 g{9 {0 quinolines and hexahydroindeno {8 1,2,b{9 {0 pyridines
LU88619I2 (fr) * 1981-10-16 1995-07-10 Sandoz Ag QUINAGOLIDE, éventuellement sous forme de sel, par exemple du chlorhydrate

Also Published As

Publication number Publication date
DK40984A (da) 1984-08-02
JPS59144761A (ja) 1984-08-18
AU571482B2 (en) 1988-04-21
IL70845A (en) 1986-09-30
FR2540112A1 (fr) 1984-08-03
DK40984D0 (da) 1984-01-30
GB8402358D0 (en) 1984-02-29
NZ206981A (en) 1987-03-31
IL70845A0 (en) 1984-05-31
FR2540112B1 (fr) 1986-08-29
SE8400445D0 (sv) 1984-01-30
IE56653B1 (en) 1991-10-23
SE8400445L (sv) 1984-08-02
DE3402601A1 (de) 1984-08-02
GB2134515B (en) 1986-07-02
NL8400259A (nl) 1984-09-03
PH22782A (en) 1988-12-12
GB2134515A (en) 1984-08-15
LU85191A1 (fr) 1984-10-24
BE898761A (fr) 1984-07-26
IE840209L (en) 1984-08-01
AU2391184A (en) 1984-08-02
IT1199056B (it) 1988-12-30
IT8447626A1 (it) 1985-08-01
US4692453A (en) 1987-09-08
IT8447626A0 (it) 1984-02-01

Similar Documents

Publication Publication Date Title
DE3461466D1 (en) 3',4',5,7-tetrahydroxyflavone derivatives, process for their preparation and their therapeutical use
EP0161877A3 (en) 1,4-dihydropyridine derivatives, methods for their production and pharmaceutical compositions comprising the same
PT80349A (en) Process for the preparation of 1,4-dihydro-4-oxonaphthyridine derivatives and salts thereof and of antibacterial agents comprising the same
AU582808B2 (en) Benzimidazole derivatives and their production and use
GR3001210T3 (en) Thiolactam-n-acetic acid derivatives, their production and use
DE3466688D1 (en) Benzimidazole derivatives, and their production and use
IL70845A0 (en) 1,2,3,4,4a,5,10,10a-octahydrobenzo(g)quinoline derivatives,their production and pharmaceutical compositions containing them
DE3568435D1 (en) 2-acetoacetylglycerol derivatives, their production and use
EP0260121A3 (en) Inosose derivatives, production and use thereof
EP0128010A3 (en) 1,4-dihydropyridine derivative, process for production thereof and pharmaceutical use thereof
IL85183A0 (en) Substituted amine derivatives,their production and use
KR960016541B1 (en) 2,5,6,7-tetranor-4,8-inter-m-phenylene pgi2 derivatives, process for their preparation and use thereof
PL268260A1 (en) Weedicidal specific and the method of manufacturing of new derivatives of 2-benzoylcyclohexandion-1,3
ZA867940B (en) Delta2-1,2,4-triazolin-5-one derivatives,process for production thereof and uses thereof
DE3268047D1 (en) Production of 11,11,12,12-tetracyano-9,10-anthraquinodimethane and derivatives thereof
GR82623B (en) Novel 1,4- naphthochinone derivatives, method for the preparation therof and their use as medicaments
ZA845708B (en) Novel 1,8-naphthyridine derivatives,and processes for preparation thereof
PT79630A (en) Process for the preparation of 1,2,4-oxo(tio)diazoline-3-one derivatives
IL73302A0 (en) Benzoylurea derivatives,their production and their use as insecticides
ZA895305B (en) Quinoline derivatives,their production and use
EP0140154A3 (en) 1,2,4-triazolylpropanols, and their production and use
ZA856402B (en) Process for the preparation of optically active,substituted 1,4-dihydropyridines and their use as medicaments
IL74010A0 (en) Sulfonylguanidine derivatives,their production and their use as herbicides
JPS6470470A (en) Novel 1,2-diamino compound, manufacture and drug
GB2178034B (en) 7,7,8,8-tetracyanoquinodimethane-2,5-ylene-(3-propionic acid), derivatives thereof and process for preparing same