ZA849274B - 5-phenyl-2(1h)pyrazinone derivatives with inotropic activity - Google Patents

5-phenyl-2(1h)pyrazinone derivatives with inotropic activity

Info

Publication number: ZA849274B
Authority: ZA; South Africa
Prior art keywords: phenyl; inotropic activity; pyrazinone derivatives; pyrazinone; derivatives
Prior art date: 1983-12-02

Application number

ZA849274A

Other languages

English (en)

Inventor

John Colin Emmett

Robert Antony Slater

Original Assignee

Smith Kline French Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-12-02

Filing date

1984-11-28

Publication date

1986-07-30

1984-11-28 Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab

1986-07-30 Publication of ZA849274B publication Critical patent/ZA849274B/xx

Links

BMGVFXUMEAYBAO-UHFFFAOYSA-N 5-phenyl-1h-pyrazin-2-one Chemical class N1C(=O)C=NC(C=2C=CC=CC=2)=C1 BMGVFXUMEAYBAO-UHFFFAOYSA-N 0.000 title 1
230000000297 inotrophic effect Effects 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/18—Oxygen or sulfur atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Heart & Thoracic Surgery (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ZA849274A 1983-12-02 1984-11-28 5-phenyl-2(1h)pyrazinone derivatives with inotropic activity ZA849274B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB838332313A GB8332313D0 (en)	1983-12-02	1983-12-02	Chemical compounds

Publications (1)

Publication Number	Publication Date
ZA849274B true ZA849274B (en)	1986-07-30

Family

ID=10552775

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA849274A ZA849274B (en)	1983-12-02	1984-11-28	5-phenyl-2(1h)pyrazinone derivatives with inotropic activity

Country Status (10)

Country	Link
US (1)	US4632924A (de)
EP (1)	EP0146282A3 (de)
JP (1)	JPS60132967A (de)
AU (1)	AU3601784A (de)
DK (1)	DK564284A (de)
ES (1)	ES8604392A1 (de)
GB (1)	GB8332313D0 (de)
GR (1)	GR81105B (de)
PT (1)	PT79570B (de)
ZA (1)	ZA849274B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8332313D0 (en) *	1983-12-02	1984-01-11	Smith Kline French Lab	Chemical compounds
AU6999996A (en) *	1995-09-22	1997-04-09	Sumitomo Chemical Company, Limited	Pyrazin-2-one derivatives, their use, and intermediates for their production

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3745161A (en) *	1970-04-20	1973-07-10	Merck & Co Inc	Phenyl-hydroxy-pyrazine carboxylic acids and derivatives
EP0052442B1 (de) *	1980-11-14	1985-09-11	Imperial Chemical Industries Plc	Heterocyclische Derivate
ZA827641B (en) *	1981-11-12	1983-09-28	Ici Plc	Thiadiazine, oxadiazine and triazine derivatives which possess cardiotonic and/or antihypertensive activity
US4402958A (en) *	1981-11-19	1983-09-06	American Cyanamid Company	Novel (substituted phenyl)-1,2,4-triazolo (4,3-A)pyrazines and novel 2-hydrazino-(substituted phenyl)pyrazine intermediates
EP0096517A3 (de) *	1982-06-05	1985-04-03	Smith Kline & French Laboratories Limited	Arylpyrazinone
US4489074A (en) *	1982-11-12	1984-12-18	Imperial Chemical Industries, Plc	1,3,4-Thiadiazin-2-ones
JPS59144772A (ja) *	1983-02-08	1984-08-18	Ube Ind Ltd	液晶性ピラジン誘導体およびその製法
GB8332313D0 (en) *	1983-12-02	1984-01-11	Smith Kline French Lab	Chemical compounds

1983
- 1983-12-02 GB GB838332313A patent/GB8332313D0/en active Pending
1984
- 1984-11-26 EP EP84308172A patent/EP0146282A3/de not_active Withdrawn
- 1984-11-28 PT PT79570A patent/PT79570B/pt unknown
- 1984-11-28 ZA ZA849274A patent/ZA849274B/xx unknown
- 1984-11-28 DK DK564284A patent/DK564284A/da not_active Application Discontinuation
- 1984-11-28 ES ES538037A patent/ES8604392A1/es not_active Expired
- 1984-11-29 GR GR81105A patent/GR81105B/el unknown
- 1984-11-29 AU AU36017/84A patent/AU3601784A/en not_active Abandoned
- 1984-11-30 US US06/677,006 patent/US4632924A/en not_active Expired - Fee Related
- 1984-12-01 JP JP59254924A patent/JPS60132967A/ja active Pending

Also Published As

Publication number	Publication date
GR81105B (en)	1985-04-01
US4632924A (en)	1986-12-30
DK564284A (da)	1985-06-03
PT79570B (en)	1986-11-14
GB8332313D0 (en)	1984-01-11
PT79570A (en)	1984-12-01
EP0146282A3 (de)	1986-03-26
EP0146282A2 (de)	1985-06-26
AU3601784A (en)	1985-06-06
ES538037A0 (es)	1986-01-16
ES8604392A1 (es)	1986-01-16
JPS60132967A (ja)	1985-07-16
DK564284D0 (da)	1984-11-28

Publication	Publication Date	Title
GB8709294D0 (en)	1987-05-20	Substituted aniline derivatives
GB8513062D0 (en)	1985-06-26	Multidriver loudspeaker
EP0123907A3 (en)	1985-10-23	Halogenopyrimidine derivatives
ZA844476B (en)	1986-02-26	Amino-pyrimidine derivatives
DE3474913D1 (en)	1988-12-08	Amino-pyrimidine derivatives
GB8421979D0 (en)	1984-10-03	Loudspeaker assembly
GB8722777D0 (en)	1987-11-04	Geometric compensation
AU92325S (en)	1986-06-05	Loudspeaker
GB8325047D0 (en)	1983-10-19	Nebulizers
AU92422S (en)	1986-06-19	Loudspeaker
GB2142025B (en)	1986-11-12	Pyrimidine derivatives
DE3462503D1 (en)	1987-04-09	Novel 5-acyl-2-(1h)-pyridinones
PH19219A (en)	1986-02-12	Novel pyrimidone derivatives
ZA849274B (en)	1986-07-30	5-phenyl-2(1h)pyrazinone derivatives with inotropic activity
GB2152508B (en)	1986-10-15	Pyrimidine derivatives
GR80749B (en)	1985-02-20	Substituted pyrimidine
ZA841166B (en)	1985-10-30	Pyrimidine derivatives
GB8308290D0 (en)	1983-05-05	Pyrimidinone derivatives
GB8407867D0 (en)	1984-05-02	Supporting feeder assembly
ZA842595B (en)	1985-11-27	Pyrimidine derivatives
AU92339S (en)	1986-06-19	Loudspeaker
GB8403282D0 (en)	1984-03-14	Loudspeaker
IE831314L (en)	1983-12-05	Pyrazinone derivatives
GB8314931D0 (en)	1983-07-06	Pyrimidine derivatives
GB8315332D0 (en)	1983-07-06	Pyrimidine derivatives