ZA854901B - Antibacterial 7-oxo-4-thia-1-azabicyclo(3,2,0)hept-2-ene derivatives - Google Patents

Antibacterial 7-oxo-4-thia-1-azabicyclo(3,2,0)hept-2-ene derivatives

Info

Publication number
ZA854901B
ZA854901B ZA854901A ZA854901A ZA854901B ZA 854901 B ZA854901 B ZA 854901B ZA 854901 A ZA854901 A ZA 854901A ZA 854901 A ZA854901 A ZA 854901A ZA 854901 B ZA854901 B ZA 854901B
Authority
ZA
South Africa
Prior art keywords
thia
azabicyclo
hept
oxo
antibacterial
Prior art date
Application number
ZA854901A
Other languages
English (en)
Inventor
Barry Clive Ross
Andrew John Barker
Nicholas Iain Carruthers
Michael David Cooke
Original Assignee
Hoechst Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Uk Ltd filed Critical Hoechst Uk Ltd
Publication of ZA854901B publication Critical patent/ZA854901B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
    • C07C69/90—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with esterified hydroxyl and carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1896—Compounds having one or more Si-O-acyl linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA854901A 1984-06-29 1985-06-28 Antibacterial 7-oxo-4-thia-1-azabicyclo(3,2,0)hept-2-ene derivatives ZA854901B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848416565A GB8416565D0 (en) 1984-06-29 1984-06-29 Antibacterial derivatives

Publications (1)

Publication Number Publication Date
ZA854901B true ZA854901B (en) 1986-02-26

Family

ID=10563160

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA854901A ZA854901B (en) 1984-06-29 1985-06-28 Antibacterial 7-oxo-4-thia-1-azabicyclo(3,2,0)hept-2-ene derivatives

Country Status (17)

Country Link
US (1) US4795748A (mo)
EP (1) EP0170028A1 (mo)
JP (1) JPS6118760A (mo)
KR (1) KR860000300A (mo)
AU (1) AU583521B2 (mo)
DK (1) DK296085A (mo)
ES (11) ES8707963A1 (mo)
FI (1) FI852554A7 (mo)
GB (2) GB8416565D0 (mo)
GR (1) GR851584B (mo)
HU (3) HU194890B (mo)
IL (1) IL75675A0 (mo)
NO (3) NO852356L (mo)
NZ (1) NZ212572A (mo)
PH (1) PH22117A (mo)
PT (1) PT80736B (mo)
ZA (1) ZA854901B (mo)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2195627A (en) * 1986-08-12 1988-04-13 Hoechst Uk Ltd Penem derivatives
EP0278911B1 (de) * 1987-02-11 1993-08-04 Ciba-Geigy Ag Bicyclische beta-Lactam-carbonsäuren
AT392903B (de) * 1987-10-08 1991-07-10 Hoechst Ag Pharmazeutische zubereitung enthaltend ein cephalosporin und ein penemantibiotikum
SE535691C2 (sv) * 2011-03-08 2012-11-13 Kat2Biz Ab Reduktion av C-O-bindningar via katalytisk transfer hydrogenolys
MX2015004636A (es) * 2012-10-12 2015-10-22 Lilly Co Eli Motores químicos y métodos para su uso, especialmente en la inyección de fluidos altamente viscosos.
JP6841937B2 (ja) 2017-02-17 2021-03-10 イーライ リリー アンド カンパニー 化学反応による流体の送達のためのプロセスおよびデバイス
CN111050826B (zh) 2017-09-08 2022-05-31 伊莱利利公司 用于控制药物递送装置内的气体生成的系统
CN113226404B (zh) 2018-12-19 2024-08-23 伊莱利利公司 用于输送治疗流体的设备
EP3897779B1 (en) 2018-12-19 2024-08-07 Eli Lilly and Company Devices and processes for delivery of therapeutic fluids

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4168314A (en) * 1977-11-17 1979-09-18 Merck & Co., Inc. 6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid
JPS5625110A (en) * 1978-12-18 1981-03-10 Bristol Myers Co Antibacterial
EP0069378B1 (en) * 1981-07-08 1987-01-07 Hoechst Uk Limited Antibacterial penem derivatives
ES8305366A1 (es) * 1981-07-08 1983-04-01 Hoechst Uk Ltd "procedimiento para la preparacion de derivados de penem".
FI77662C (fi) * 1982-07-08 1989-04-10 Hoechst Uk Ltd Foerfarande foer framstaellning av nya antibakteriella penemderivat.
GB2164334B (en) * 1984-09-10 1988-08-03 Hoechst Uk Ltd Antibacterial 7-oxo-4-thia-1-azabicyclo 3,2,0 hept-2-ene derivativess

Also Published As

Publication number Publication date
ES8801661A1 (es) 1988-02-16
FI852554L (fi) 1985-12-30
ES8800898A1 (es) 1987-12-01
ES8707540A1 (es) 1987-08-01
DK296085A (da) 1985-12-30
GR851584B (mo) 1985-11-25
ES551562A0 (es) 1988-02-16
GB2161161A (en) 1986-01-08
PH22117A (en) 1988-06-01
HU194890B (en) 1988-03-28
NO860975L (no) 1985-12-30
US4795748A (en) 1989-01-03
ES9000004A1 (es) 1988-12-16
DK296085D0 (da) 1985-06-28
HUT37942A (en) 1986-03-28
GB8416565D0 (en) 1984-08-01
HU196748B (en) 1989-01-30
ES557087A0 (es) 1987-08-01
ES8707495A1 (es) 1987-08-01
ES557535A0 (es) 1988-02-16
AU4440885A (en) 1986-01-02
NZ212572A (en) 1989-02-24
KR860000300A (ko) 1986-01-27
ES557088A0 (es) 1987-08-01
NO852356L (no) 1985-12-30
ES551561A0 (es) 1988-12-16
JPS6118760A (ja) 1986-01-27
ES8707963A1 (es) 1987-09-01
ES8707539A1 (es) 1987-08-01
ES557086A0 (es) 1987-08-01
ES557090A0 (es) 1987-08-01
FI852554A7 (fi) 1985-12-30
ES557092A0 (es) 1987-12-01
ES8707497A1 (es) 1987-08-01
EP0170028A1 (en) 1986-02-05
ES8801660A1 (es) 1988-02-16
GB2161161B (en) 1989-05-24
ES557091A0 (es) 1987-08-01
ES544625A0 (es) 1987-09-01
ES557089A0 (es) 1987-08-01
ES8707498A1 (es) 1987-08-01
HU196809B (en) 1989-01-30
NO860974L (no) 1985-12-30
PT80736A (en) 1985-10-01
AU583521B2 (en) 1989-05-04
ES8707496A1 (es) 1987-08-01
IL75675A0 (en) 1985-10-31
PT80736B (en) 1987-03-17
FI852554A0 (fi) 1985-06-27
GB8516493D0 (en) 1985-07-31

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