ZA856807B - A tumor therapeutic agent and a process for its preparation - Google Patents

A tumor therapeutic agent and a process for its preparation

Info

Publication number
ZA856807B
ZA856807B ZA856807A ZA856807A ZA856807B ZA 856807 B ZA856807 B ZA 856807B ZA 856807 A ZA856807 A ZA 856807A ZA 856807 A ZA856807 A ZA 856807A ZA 856807 B ZA856807 B ZA 856807B
Authority
ZA
South Africa
Prior art keywords
therapeutic agent
preparation
tumor therapeutic
monoclonal antibodies
antigens
Prior art date
Application number
ZA856807A
Inventor
Klaus Bosslet
Hans-Harald Sedlacek
Original Assignee
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke Ag filed Critical Behringwerke Ag
Publication of ZA856807B publication Critical patent/ZA856807B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Window Of Vehicle (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)

Abstract

The process entails either tumour cells which carry antigens which are bound by the monoclonal antibodies described in German Offenlegungsschrift 33 29 184 being dried or stabilised by a chemical treatment, or antigens being isolated from human cells using these monoclonal antibodies, and converted into a therapeutic agent, adding neuraminidase where appropriate.
ZA856807A 1984-09-06 1985-09-05 A tumor therapeutic agent and a process for its preparation ZA856807B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843432714 DE3432714A1 (en) 1984-09-06 1984-09-06 TUMOR THERAPEUTICS AND METHOD FOR THE PRODUCTION THEREOF

Publications (1)

Publication Number Publication Date
ZA856807B true ZA856807B (en) 1986-04-30

Family

ID=6244749

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA856807A ZA856807B (en) 1984-09-06 1985-09-05 A tumor therapeutic agent and a process for its preparation

Country Status (13)

Country Link
EP (1) EP0173951B1 (en)
JP (1) JPS6168427A (en)
AT (1) ATE64531T1 (en)
CA (1) CA1277600C (en)
DE (2) DE3432714A1 (en)
DK (1) DK172253B1 (en)
ES (1) ES8704082A1 (en)
FI (1) FI88360C (en)
GR (1) GR852149B (en)
IE (1) IE58638B1 (en)
IL (1) IL76289A (en)
PT (1) PT81093B (en)
ZA (1) ZA856807B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3806565A1 (en) * 1988-03-01 1989-09-14 Deutsches Krebsforsch VIRUS-MODIFIED TUMOR VACCINES FOR THE IMMUNOTHERAPY OF TUMOR METAL KEYS
AT398900B (en) * 1991-02-12 1995-02-27 Pekar Rudolf Dr Vaccine for immunotherapy
US7070782B1 (en) 1992-11-05 2006-07-04 Sloan-Kettering Institute For Cancer Research Prostate-specific membrane antigen
US7105159B1 (en) 1992-11-05 2006-09-12 Sloan-Kettering Institute For Cancer Research Antibodies to prostate-specific membrane antigen
DE69334071T2 (en) * 1992-11-05 2007-10-25 Sloan-Kettering Institute For Cancer Research PROSTATE-SPECIFIC MEMBRANEANT
US6953668B1 (en) 1992-11-05 2005-10-11 Sloan-Kettering Institute For Cancer Research Prostate-specific membrane antigen
US6569432B1 (en) 1995-02-24 2003-05-27 Sloan-Kettering Institute For Cancer Research Prostate-specific membrane antigen and uses thereof
DE19506483A1 (en) * 1995-02-24 1996-08-29 Jens Dr Dr Atzpodien Antitumour vaccines
AU717937B2 (en) 1995-02-24 2000-04-06 Sloan-Kettering Institute For Cancer Research Prostate-specific membrane antigen and uses thereof
JP5355839B2 (en) 2001-10-23 2013-11-27 ピーエスエムエー デベロプメント カンパニー， エル．エル．シー． PSMA antibodies and protein multimers
US20050215472A1 (en) 2001-10-23 2005-09-29 Psma Development Company, Llc PSMA formulations and uses thereof
CN1315536C (en) * 2002-09-13 2007-05-16 李进 Novel vaccine of tumor antigen, its preparation method and vaccine composition

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4152410A (en) * 1975-09-03 1979-05-01 Eisai Co., Ltd. Diagnosis reagent for neoplasm and method for diagnosis of neoplasm
DE2643215A1 (en) * 1976-09-25 1978-04-06 Bayer Ag CANCEROSTATICALLY EFFECTIVE PREPARATIONS FROM TUMOR CELLS AND A METHOD FOR THEIR PRODUCTION
ZA776822B (en) * 1976-11-24 1979-06-27 D Mccollester Vaccine and method for immunotherapy of neoplastic disease
DE2918927A1 (en) * 1979-05-10 1980-11-20 Hans Prof Dr Limburg MEDICINAL PRODUCT FOR TREATING CARCINOMAS AND METHOD FOR THE PRODUCTION THEREOF
US4446122A (en) * 1979-12-28 1984-05-01 Research Corporation Purified human prostate antigen
US4468457A (en) * 1981-06-01 1984-08-28 David M. Goldenberg Method for producing a CSAp tryptic peptide and anti-CSAp antibodies
DE3329184A1 (en) * 1983-08-12 1985-02-21 Behringwerke Ag, 3550 Marburg MONOCLONAL ANTIBODIES WITH SPECIFICITY FOR MEMBRANE-ASSOCIATED ANTIGENS
DE3416774A1 (en) * 1984-05-07 1985-11-14 Behringwerke Ag, 3550 Marburg MONOCLONAL ANTIBODIES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE

Also Published As

Publication number Publication date
ATE64531T1 (en) 1991-07-15
PT81093A (en) 1985-10-01
IE58638B1 (en) 1993-10-20
DK172253B1 (en) 1998-02-09
IL76289A (en) 1992-01-15
DK402485D0 (en) 1985-09-03
JPS6168427A (en) 1986-04-08
GR852149B (en) 1986-01-03
EP0173951B1 (en) 1991-06-19
EP0173951A3 (en) 1988-06-08
FI88360B (en) 1993-01-29
PT81093B (en) 1988-07-01
DK402485A (en) 1986-03-07
FI853389L (en) 1986-03-07
IL76289A0 (en) 1986-01-31
FI853389A0 (en) 1985-09-04
CA1277600C (en) 1990-12-11
EP0173951A2 (en) 1986-03-12
FI88360C (en) 1993-05-10
DE3432714A1 (en) 1986-04-24
IE852191L (en) 1986-03-06
ES546701A0 (en) 1987-03-16
DE3583265D1 (en) 1991-07-25
ES8704082A1 (en) 1987-03-16

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