ZA872565B - 4-substituted octahydroquinolizine analgesic compounds and octahydroquinolizinium intermediates - Google Patents

4-substituted octahydroquinolizine analgesic compounds and octahydroquinolizinium intermediates

Info

Publication number
ZA872565B
ZA872565B ZA872565A ZA872565A ZA872565B ZA 872565 B ZA872565 B ZA 872565B ZA 872565 A ZA872565 A ZA 872565A ZA 872565 A ZA872565 A ZA 872565A ZA 872565 B ZA872565 B ZA 872565B
Authority
ZA
South Africa
Prior art keywords
octahydroquinolizinium
intermediates
analgesic compounds
octahydroquinolizine
substituted
Prior art date
Application number
ZA872565A
Other languages
English (en)
Inventor
Richard Joel Carmosin
Joel Carmosin Richard
John Robert Carson
Robert Carson John
Original Assignee
Mcneilab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcneilab Inc filed Critical Mcneilab Inc
Publication of ZA872565B publication Critical patent/ZA872565B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA872565A 1986-04-10 1987-04-09 4-substituted octahydroquinolizine analgesic compounds and octahydroquinolizinium intermediates ZA872565B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/850,631 US4716172A (en) 1986-04-10 1986-04-10 4-substituted octahydroquinolizine analgesic compounds and octahydroquinolizinium intermediates

Publications (1)

Publication Number Publication Date
ZA872565B true ZA872565B (en) 1988-11-30

Family

ID=25308700

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA872565A ZA872565B (en) 1986-04-10 1987-04-09 4-substituted octahydroquinolizine analgesic compounds and octahydroquinolizinium intermediates

Country Status (6)

Country Link
US (1) US4716172A (da)
EP (1) EP0241292A3 (da)
JP (1) JPS62270579A (da)
AU (1) AU599644B2 (da)
DK (1) DK182487A (da)
ZA (1) ZA872565B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4800207A (en) * 1987-11-02 1989-01-24 Mcneilab, Inc. Hexahydropyrrolizine compounds useful as analgesics
GB9314973D0 (en) * 1993-07-20 1993-09-01 Smithkline Beecham Plc Medicaments
WO1999065897A1 (en) 1998-06-19 1999-12-23 Chiron Corporation Inhibitors of glycogen synthase kinase 3
US7045519B2 (en) 1998-06-19 2006-05-16 Chiron Corporation Inhibitors of glycogen synthase kinase 3

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1545661A1 (de) * 1964-03-30 1969-08-07 Chugai Pharmaceutical Co Ltd Verfahren zur Herstellung von neuen Chinolizidin-Derivaten
GB1096589A (en) * 1964-03-31 1967-12-29 Chugai Pharmaceutical Co Ltd Novel quinolizidine derivatives or salts thereof and process for preparing the same
DK116181A (da) * 1980-04-11 1981-10-12 Hoffmann La Roche Fremgangsmaade til fremstilling af quinolizidinderivater
US4582836A (en) * 1985-01-09 1986-04-15 Mcneilab, Inc. Octahydroindolizine compounds useful as analgesics

Also Published As

Publication number Publication date
AU599644B2 (en) 1990-07-26
DK182487A (da) 1987-10-11
DK182487D0 (da) 1987-04-09
EP0241292A2 (en) 1987-10-14
AU7136187A (en) 1987-10-15
JPS62270579A (ja) 1987-11-24
EP0241292A3 (en) 1989-03-15
US4716172A (en) 1987-12-29

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