ZA875897B - Estradiol implant composition and method for preparation - Google Patents

Estradiol implant composition and method for preparation

Info

Publication number
ZA875897B
ZA875897B ZA875897A ZA875897A ZA875897B ZA 875897 B ZA875897 B ZA 875897B ZA 875897 A ZA875897 A ZA 875897A ZA 875897 A ZA875897 A ZA 875897A ZA 875897 B ZA875897 B ZA 875897B
Authority
ZA
South Africa
Prior art keywords
preparation
estradiol
implant composition
time
extended periods
Prior art date
Application number
ZA875897A
Other languages
English (en)
Inventor
Mimi Yih-Pei Chou Schaaf
Yih-Pei Chou Schaaf Mimi
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of ZA875897B publication Critical patent/ZA875897B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
ZA875897A 1986-08-11 1987-08-10 Estradiol implant composition and method for preparation ZA875897B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/895,415 US4758435A (en) 1986-08-11 1986-08-11 Estradiol implant composition and method for preparation

Publications (1)

Publication Number Publication Date
ZA875897B true ZA875897B (en) 1988-05-25

Family

ID=25404471

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA875897A ZA875897B (en) 1986-08-11 1987-08-10 Estradiol implant composition and method for preparation

Country Status (10)

Country Link
US (1) US4758435A (de)
EP (1) EP0257369B1 (de)
AT (1) ATE74751T1 (de)
AU (1) AU599406B2 (de)
CA (1) CA1297020C (de)
DE (1) DE3778244D1 (de)
ES (1) ES2031096T3 (de)
GR (1) GR3004370T3 (de)
NZ (1) NZ221390A (de)
ZA (1) ZA875897B (de)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4846844A (en) * 1987-08-31 1989-07-11 Eli Lilly And Company Antimicrobial coated implants
DE3734223A1 (de) * 1987-10-09 1989-04-20 Boehringer Ingelheim Kg Implantierbares, biologisch abbaubares wirkstofffreigabesystem
US5250584A (en) * 1988-08-31 1993-10-05 G-C Dental Industrial Corp. Periodontium-regenerative materials
FR2654337B1 (fr) * 1989-11-15 1994-08-05 Roussel Uclaf Nouvelles microspheres injectables biodegradables procede de preparation et suspensions injectables les renfermant.
US5198220A (en) * 1989-11-17 1993-03-30 The Procter & Gamble Company Sustained release compositions for treating periodontal disease
EP0447719B1 (de) * 1990-03-05 1993-11-03 Minnesota Mining And Manufacturing Company Vorrichtung zur verzögerten Abgabe von pharmakologisch aktiven Verbindungen ins Ohr
US5350580A (en) * 1990-03-05 1994-09-27 Minnesota Mining And Manufacturing Company Device and method for extended delivery of pharmacologically active agents to the ear
US5288496A (en) * 1990-05-15 1994-02-22 Stolle Research & Development Corporation Growth promoters for animals
US5686092A (en) * 1992-11-24 1997-11-11 Alkermes Controlled Therapeutics Inc. Ii Growth promoters for animals
US20020111603A1 (en) 1996-12-02 2002-08-15 Societe De Conseils De Recherches Et D'application Device for local administration of solid or semi-solid formulations and delayed-release formulations for proposal parental administration and preparation process
FR2756493B1 (fr) * 1996-12-02 2001-04-13 Delab Dispositif d'administration locale de formulations solides ou semi-solides
DE19744135C1 (de) * 1997-09-29 1999-03-25 Schering Ag Beschichtete medizinische Implantate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Restenoseprophylaxe
US6022554A (en) * 1997-12-15 2000-02-08 American Home Products Corporation Polymeric microporous film coated subcutaneous implant
ES2359973T3 (es) 1998-03-19 2011-05-30 MERCK SHARP & DOHME CORP. Composiciones poliméricas líquidas para la liberación controlada de sustancias bioactivas.
FR2770134B1 (fr) * 1998-10-28 2002-06-07 Delab Formulations solides ou semi-solides pour administration locale
US7767708B2 (en) * 1998-11-04 2010-08-03 Schering-Plough Animal Health Corp. Growth stimulant compositions
US6498153B1 (en) 1998-12-31 2002-12-24 Akzo Nobel N.V. Extended release growth promoting two component composition
US6787342B2 (en) 2000-02-16 2004-09-07 Merial Limited Paste formulations
US6953586B1 (en) * 2000-06-08 2005-10-11 Ivy Animal Health, Inc. Growth promoting pharmaceutical implant
WO2007011708A2 (en) 2005-07-15 2007-01-25 Micell Technologies, Inc. Stent with polymer coating containing amorphous rapamycin
WO2007011707A2 (en) 2005-07-15 2007-01-25 Micell Technologies, Inc. Polymer coatings containing drug powder of controlled morphology
US8362086B2 (en) 2005-08-19 2013-01-29 Merial Limited Long acting injectable formulations
CA2996768C (en) 2006-04-26 2020-12-08 Micell Technologies, Inc. Coatings containing multiple drugs
EP2236546B1 (de) * 2006-10-31 2011-12-28 Surmodics Pharmaceuticals, Inc. Kugelförmige Polymer-Partikel
CA2679712C (en) 2007-01-08 2016-11-15 Micell Technologies, Inc. Stents having biodegradable layers
US11426494B2 (en) 2007-01-08 2022-08-30 MT Acquisition Holdings LLC Stents having biodegradable layers
SG192523A1 (en) 2008-04-17 2013-08-30 Micell Technologies Inc Stents having bioabsorbable layers
KR20130097813A (ko) 2008-04-21 2013-09-03 오토노미, 인코포레이티드 귀 질환 및 병태를 치료하기 위한 귀 조제물
EP2313122B1 (de) 2008-07-17 2019-03-06 Micell Technologies, Inc. Medizinische wirkstofffreisetzungsvorrichtung
AU2009270695A1 (en) 2008-07-17 2010-01-21 Ap Pharma Methods for enhancing the stability of polyorthoesters and their formulations
US9510856B2 (en) 2008-07-17 2016-12-06 Micell Technologies, Inc. Drug delivery medical device
US8784870B2 (en) 2008-07-21 2014-07-22 Otonomy, Inc. Controlled release compositions for modulating free-radical induced damage and methods of use thereof
JP5421366B2 (ja) 2008-07-21 2014-02-19 オトノミ―，インク． 制御放出性の耳の構造体調節および生来の免疫システム調節化合物および耳の障害の処置のための方法
WO2010120552A2 (en) 2009-04-01 2010-10-21 Micell Technologies, Inc. Coated stents
WO2010121187A2 (en) 2009-04-17 2010-10-21 Micell Techologies, Inc. Stents having controlled elution
US11369498B2 (en) 2010-02-02 2022-06-28 MT Acquisition Holdings LLC Stent and stent delivery system with improved deliverability
CA2797110C (en) 2010-04-22 2020-07-21 Micell Technologies, Inc. Stents and other devices having extracellular matrix coating
EP2590628A1 (de) * 2010-06-30 2013-05-15 Evonik Corporation Implantatverarbeitungsverfahren für thermisch labile und andere bioaktive mittel sowie daraus hergestellte implantate
EP2593039B1 (de) 2010-07-16 2022-11-30 Micell Technologies, Inc. Medizinische wirkstofffreisetzungsvorrichtung
US10117972B2 (en) 2011-07-15 2018-11-06 Micell Technologies, Inc. Drug delivery medical device
US10188772B2 (en) 2011-10-18 2019-01-29 Micell Technologies, Inc. Drug delivery medical device
BR112014013371B1 (pt) * 2011-12-02 2020-04-07 Merial Ltd formulações de moxidectina injetável de ação prolongada e novas formas de cristal de moxidectina
AU2014248508B2 (en) 2013-03-12 2018-11-08 Micell Technologies, Inc. Bioabsorbable biomedical implants
WO2014186532A1 (en) 2013-05-15 2014-11-20 Micell Technologies, Inc. Bioabsorbable biomedical implants
US10226419B2 (en) 2014-09-08 2019-03-12 ProMed Pharma, LLC Methods for manufacturing implants
CA2993645A1 (en) 2015-07-28 2017-02-02 Otonomy, Inc. Trkb or trkc agonist compositions and methods for the treatment of otic conditions
JP7033789B2 (ja) 2016-06-29 2022-03-11 オトノミー，インク． トリグリセリド耳用製剤とその使用
CA3087574A1 (en) 2018-01-09 2019-07-18 Otonomy, Inc. Growth factor otic formulations
US20230355542A1 (en) * 2022-05-04 2023-11-09 Yasin Oduk Drug-eluting device with genetic and chemical therapeutics for treating or preventing vascular access dysfunctions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
CA1076480A (en) * 1975-04-28 1980-04-29 John S. Kent Inert core implant pellet
US4191741A (en) * 1978-09-22 1980-03-04 Eli Lilly And Company Removable drug implant
US4293539A (en) * 1979-09-12 1981-10-06 Eli Lilly And Company Controlled release formulations and method of treatment
DK119884A (da) * 1983-03-18 1984-09-19 Lilly Co Eli Fast, cylindrisk, subkutan implantation og dens anvendelse
CA1256638A (en) * 1984-07-06 1989-06-27 Motoaki Tanaka Polymer and its production

Also Published As

Publication number Publication date
EP0257369B1 (de) 1992-04-15
CA1297020C (en) 1992-03-10
AU599406B2 (en) 1990-07-19
GR3004370T3 (de) 1993-03-31
DE3778244D1 (de) 1992-05-21
EP0257369A1 (de) 1988-03-02
US4758435A (en) 1988-07-19
NZ221390A (en) 1990-10-26
ES2031096T3 (es) 1992-12-01
ATE74751T1 (de) 1992-05-15
AU7672487A (en) 1988-02-18

Similar Documents

Publication Publication Date Title
ZA875897B (en) Estradiol implant composition and method for preparation
MY113488A (en) Compounds with growth hormone releasing properties
IL78826A (en) Precursor composition for the preparation of a biodegradable implant for the sustained release of an active material and such implants prepared therefrom
HUT58058A (en) Insecticidal composition and process for producing its active ingredient, 1-phenylimidazole derivatives
EP0152148A3 (en) Pharmaceutica composition for the treatment of acute myocardial ischemia
CA2195119A1 (en) Formulations and methods for providing prolonged local anesthesia
HUT47390A (en) Fungicidal and plant growth regulating compositions comprising 1-azolyl-2-cyclopropyl-3-phenyl-2-propanol derivatives as active ingredient and process for producing the active ingredients and their intermediates
CA2121674A1 (en) Biocompatible implant for the timing of ovulation in mares
HUT53873A (en) Insecticides comprising nitro compounds as active ingredient and process for producing the active ingredients
EP0268463A3 (en) Zinc based ceramics
HU900221D0 (en) Fungicid composition comprising acyl-amino-benzamides as active ingredient and process for preparation thereof
HUT52083A (en) Herbicidal compositions comprising cyclohexenone oxymetres as active ingredient and process for producing the active ingredients
ES545744A0 (es) Un procedimiento para la preparacion de bencenoacetonitrilos.
HUT45531A (en) Process for producing bactericidal compositions, fodder additives and 7-azabicycloalkyl-quinolonecarboxylic acid and naphthiridinecarboxylic acid derivatives applicable as active ingredient
HUT49591A (en) Plant growth regulating and fungicidal compositions comprising pyrimidine derivatives as active ingredient and process for producing the active ingredients
IL79134A (en) Continuous release peptide implants for parenteral administration
EP1721617A3 (de) Zahnärztliche Therapeutika enthaltend Parathyroidhormon
HUT46508A (en) Insecticidal compositions comprising 6-member heterocyclic derivatives of n'-substituted-n,n'-diacylhydrazine and process for producing the active ingredients
HUT54358A (en) Process for producing substituted 1,3,5-triazinetrione derivatives and medical compositions comprising such compounds as active ingredient
IL106288A0 (en) Skin regenerating cosmetic compositions
HUT39962A (en) Herbicide compositions containing 2,4-diamino-pyrimidine derivatives as active ingredients and process for preparing the active ingredients
HUT54289A (en) Fungicidal compositions comprising guanidine derivatives as active ingredient and process for producing the active ingredients
HUT63306A (en) Insecticidal compositions comprising guanide derivatives as active ingredient and process for producing the active ingredient
HUT48096A (en) Insecticides comprising 2-imino-1,3-dithiethane derivatives as active ingredient and process for producing the active ingredients
HUT46364A (en) Process for producing 1,12-dihydroxy-1,6,12,13-tetraaza-dicyclodocosane-2,5,13,16-tetron and pharmaceutical compositions comprising this compound as active ingredient